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Neurological symptom

MedGen UID:
66714
Concept ID:
C0235031
Sign or Symptom
Synonyms: Neurologic Symptom; Neurologic Symptoms; Symptom, Neurologic; Symptoms, Neurologic
SNOMED CT: Neurological symptom (308921004); Symptom of nervous system (308921004)

Definition

A term that refers to the clinical manifestations resulting from pathologic processes that affect the central and peripheral nervous system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurological symptom

Professional guidelines

PubMed

Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N
Lancet Infect Dis 2021 Oct;21(10):1441-1447. Epub 2021 May 26 doi: 10.1016/S1473-3099(20)30857-4. PMID: 34051142
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Geberhiwot T, Moro A, Dardis A, Ramaswami U, Sirrs S, Marfa MP, Vanier MT, Walterfang M, Bolton S, Dawson C, Héron B, Stampfer M, Imrie J, Hendriksz C, Gissen P, Crushell E, Coll MJ, Nadjar Y, Klünemann H, Mengel E, Hrebicek M, Jones SA, Ory D, Bembi B, Patterson M; International Niemann-Pick Disease Registry (INPDR)
Orphanet J Rare Dis 2018 Apr 6;13(1):50. doi: 10.1186/s13023-018-0785-7. PMID: 29625568Free PMC Article

Recent clinical studies

Etiology

Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N
Lancet Infect Dis 2021 Oct;21(10):1441-1447. Epub 2021 May 26 doi: 10.1016/S1473-3099(20)30857-4. PMID: 34051142
El-Nahas MR, Elkannishy G, Abdelhafez H, Elkhamisy ET, El-Sehrawy AA
Endocr Metab Immune Disord Drug Targets 2020;20(9):1531-1534. doi: 10.2174/1871530320666200506081407. PMID: 32370731
Wang H
Curr Pharm Des 2020;25(43):4579-4588. doi: 10.2174/1381612825666191210155059. PMID: 31820697
Fobian AD, Elliott L
J Psychiatry Neurosci 2019 Jan 1;44(1):8-18. doi: 10.1503/jpn.170190. PMID: 30565902Free PMC Article
Dworetzky BA, Baslet G
Semin Neurol 2017 Dec;37(6):624-631. Epub 2017 Dec 21 doi: 10.1055/s-0037-1607971. PMID: 29270935

Diagnosis

Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N
Lancet Infect Dis 2021 Oct;21(10):1441-1447. Epub 2021 May 26 doi: 10.1016/S1473-3099(20)30857-4. PMID: 34051142
El-Nahas MR, Elkannishy G, Abdelhafez H, Elkhamisy ET, El-Sehrawy AA
Endocr Metab Immune Disord Drug Targets 2020;20(9):1531-1534. doi: 10.2174/1871530320666200506081407. PMID: 32370731
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Galli S, Tatu L, Bogousslavsky J, Aybek S
Front Neurol Neurosci 2018;42:72-80. Epub 2017 Nov 17 doi: 10.1159/000475699. PMID: 29151092
Spiegel D, Lewis-Fernández R, Lanius R, Vermetten E, Simeon D, Friedman M
Annu Rev Clin Psychol 2013;9:299-326. Epub 2013 Feb 1 doi: 10.1146/annurev-clinpsy-050212-185531. PMID: 23394228

Therapy

Valencia-Sanchez C, Sechi E, Dubey D, Flanagan EP, McKeon A, Pittock SJ, Zekeridou A
Eur J Neurol 2023 Aug;30(8):2418-2429. Epub 2023 May 18 doi: 10.1111/ene.15835. PMID: 37151179
Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N
Lancet Infect Dis 2021 Oct;21(10):1441-1447. Epub 2021 May 26 doi: 10.1016/S1473-3099(20)30857-4. PMID: 34051142
El-Nahas MR, Elkannishy G, Abdelhafez H, Elkhamisy ET, El-Sehrawy AA
Endocr Metab Immune Disord Drug Targets 2020;20(9):1531-1534. doi: 10.2174/1871530320666200506081407. PMID: 32370731
Wang H
Curr Pharm Des 2020;25(43):4579-4588. doi: 10.2174/1381612825666191210155059. PMID: 31820697
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article

Prognosis

Thom RP, Balaj K, Keary CJ, Pober BR, McDougle CJ
J Acad Consult Liaison Psychiatry 2022 Mar-Apr;63(2):170-179. Epub 2021 Oct 5 doi: 10.1016/j.jaclp.2021.09.007. PMID: 34619410
Takahashi H, Isogawa M
Chin Clin Oncol 2018 Jun;7(3):30. doi: 10.21037/cco.2018.05.06. PMID: 30056732
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Geberhiwot T, Moro A, Dardis A, Ramaswami U, Sirrs S, Marfa MP, Vanier MT, Walterfang M, Bolton S, Dawson C, Héron B, Stampfer M, Imrie J, Hendriksz C, Gissen P, Crushell E, Coll MJ, Nadjar Y, Klünemann H, Mengel E, Hrebicek M, Jones SA, Ory D, Bembi B, Patterson M; International Niemann-Pick Disease Registry (INPDR)
Orphanet J Rare Dis 2018 Apr 6;13(1):50. doi: 10.1186/s13023-018-0785-7. PMID: 29625568Free PMC Article
Vasudevan C, Levene M
Semin Fetal Neonatal Med 2013 Aug;18(4):185-91. Epub 2013 Jun 5 doi: 10.1016/j.siny.2013.05.008. PMID: 23746578

Clinical prediction guides

Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N
Lancet Infect Dis 2021 Oct;21(10):1441-1447. Epub 2021 May 26 doi: 10.1016/S1473-3099(20)30857-4. PMID: 34051142
El-Nahas MR, Elkannishy G, Abdelhafez H, Elkhamisy ET, El-Sehrawy AA
Endocr Metab Immune Disord Drug Targets 2020;20(9):1531-1534. doi: 10.2174/1871530320666200506081407. PMID: 32370731
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Geberhiwot T, Moro A, Dardis A, Ramaswami U, Sirrs S, Marfa MP, Vanier MT, Walterfang M, Bolton S, Dawson C, Héron B, Stampfer M, Imrie J, Hendriksz C, Gissen P, Crushell E, Coll MJ, Nadjar Y, Klünemann H, Mengel E, Hrebicek M, Jones SA, Ory D, Bembi B, Patterson M; International Niemann-Pick Disease Registry (INPDR)
Orphanet J Rare Dis 2018 Apr 6;13(1):50. doi: 10.1186/s13023-018-0785-7. PMID: 29625568Free PMC Article
Vasudevan C, Levene M
Semin Fetal Neonatal Med 2013 Aug;18(4):185-91. Epub 2013 Jun 5 doi: 10.1016/j.siny.2013.05.008. PMID: 23746578

Recent systematic reviews

Patwal R, Jolly AJ, Kumar A, Yadav R, Desai G, Thippeswamy H
J Psychosom Res 2023 May;168:111196. Epub 2023 Feb 21 doi: 10.1016/j.jpsychores.2023.111196. PMID: 36868109
Wang C, Zhang L, Li T, Xi Z, Wu H, Li D
J Cardiothorac Surg 2022 Jun 3;17(1):140. doi: 10.1186/s13019-022-01894-8. PMID: 35659278Free PMC Article
Rossetti MG, Delvecchio G, Calati R, Perlini C, Bellani M, Brambilla P
Neurosci Biobehav Rev 2021 Mar;122:66-78. Epub 2020 Dec 20 doi: 10.1016/j.neubiorev.2020.12.017. PMID: 33359097
Collantes MEV, Espiritu AI, Sy MCC, Anlacan VMM, Jamora RDG
Can J Neurol Sci 2021 Jan;48(1):66-76. Epub 2020 Jul 15 doi: 10.1017/cjn.2020.146. PMID: 32665054Free PMC Article
Chao TK, Hu J, Pringsheim T
Neurotoxicology 2017 Jul;61:79-99. Epub 2017 Jan 20 doi: 10.1016/j.neuro.2017.01.005. PMID: 28111121

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