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Foreign body granuloma

MedGen UID:
6672
•Concept ID:
C0018193
•
Pathologic Function
Synonyms: Foreign Body Granuloma; Foreign-Body Granuloma; Foreign-Body Granulomas; Granuloma, Foreign Body; Granuloma, Foreign-Body; Granulomas, Foreign-Body
SNOMED CT: Foreign body granuloma (37058002)

Definition

An inflammatory lesion comprised of epithelioid histiocytes and chronic inflammation that is caused by the presence of extraneous material. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVForeign body granuloma

Professional guidelines

PubMed

Orbital Approaches for Treatment of Carotid Cavernous Fistulas: A Systematic Review.
Phan K, Xu J, Leung V, Teng I, Sheik-Ali S, Maharaj M, Mobbs R, Rao PJ
World Neurosurg 2016 Dec;96:243-251. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.087. PMID: 27586179
Amalgam tattoo (amalgam pigmentation) of the oral mucosa: clinical manifestations, diagnosis and treatment.
Buchner A
Refuat Hapeh Vehashinayim (1993) 2004 Jul;21(3):25-8, 92. PMID: 15503979
Amalgam tattoo (amalgam pigmentation) of the oral mucosa: clinical manifestations, diagnosis and treatment.
Buchner A
Refuat Hapeh Vehashinayim (1993) 2004 Apr;21(2):19-22, 96. PMID: 15503543

Recent clinical studies

Etiology

Foreign Body Granuloma Originating From the Lateral Process of Malleus: A Case Series of 19 Children.
Mao Y, Li L, Yan W, Lu Y, Li W, Zheng J, Fan Z, Wang H, Han Y
Otol Neurotol 2023 Aug 1;44(7):702-708. Epub 2023 Jun 12 doi: 10.1097/MAO.0000000000003918. PMID: 37311639Free PMC Article
Conjunctival Foreign Body Granuloma after Pterygium Excision and Adaptation by Polyglactin Sutures.
Gerding H, Lipke K, Raak P, Brabeck C, Schlageter M, Tappeiner C, Goldblum D
Klin Monbl Augenheilkd 2023 Apr;240(4):391-393. Epub 2023 Apr 25 doi: 10.1055/a-2004-5330. PMID: 37164416
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Intracranial Foreign Body Granuloma Mimicking Brain Tumor Recurrence: A Case Series.
Winter SF, Forst DA, Oakley DH, Batchelor TT, Dietrich J
Oncologist 2021 May;26(5):e893-e897. Epub 2021 Apr 11 doi: 10.1002/onco.13766. PMID: 33780077Free PMC Article
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360

Diagnosis

Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Clinical and histopathological features of conjunctival "Teddy bear" granuloma: A case series.
Lozano-Bustillo A, Ríos Y Valles-Valles D, Hernández-Ayuso I, Rodríguez-Reyes AA
Eur J Ophthalmol 2022 Nov;32(6):3674-3678. Epub 2022 Mar 1 doi: 10.1177/11206721221083135. PMID: 35230194
Foreign body granuloma from a gunshot injury to the breast.
Chung HL, Leung JWT
Clin Imaging 2020 Dec;68:197-201. Epub 2020 Aug 27 doi: 10.1016/j.clinimag.2020.08.021. PMID: 32892104
Occupational dermatosis.
Alchorne Ade O, Alchorne MM, Silva MM
An Bras Dermatol 2010 Mar-Apr;85(2):137-45; quiz 146-7. doi: 10.1590/s0365-05962010000200003. PMID: 20520928
Chondroid syringoma.
Satter EK, Graham BS
Cutis 2003 Jan;71(1):49-52, 55. PMID: 12553630

Therapy

Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Analysis of nine cases of oral foreign body granuloma related to biomaterials.
Rolim LSA, Barros CCDS, Pinheiro JC, DE Oliveira PT, DE Souza LB, Santos PPA
J Biosci 2019 Sep;44(4) PMID: 31502556
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360
Foreign Body Granuloma After Cranial Surgery: A Systematic Review of Reported Cases.
Akhaddar A, Turgut AT, Turgut M
World Neurosurg 2018 Dec;120:457-475. Epub 2018 Sep 27 doi: 10.1016/j.wneu.2018.09.143. PMID: 30267951
Understanding the safety and tolerability of facial filling therapeutics.
Kulichova D, Borovaya A, Ruzicka T, Thomas P, Gauglitz GG
Expert Opin Drug Saf 2014 Sep;13(9):1215-26. Epub 2014 Jul 18 doi: 10.1517/14740338.2014.939168. PMID: 25036318

Prognosis

Foreign Body Granuloma Originating From the Lateral Process of Malleus: A Case Series of 19 Children.
Mao Y, Li L, Yan W, Lu Y, Li W, Zheng J, Fan Z, Wang H, Han Y
Otol Neurotol 2023 Aug 1;44(7):702-708. Epub 2023 Jun 12 doi: 10.1097/MAO.0000000000003918. PMID: 37311639Free PMC Article
Conjunctival Foreign Body Granuloma after Pterygium Excision and Adaptation by Polyglactin Sutures.
Gerding H, Lipke K, Raak P, Brabeck C, Schlageter M, Tappeiner C, Goldblum D
Klin Monbl Augenheilkd 2023 Apr;240(4):391-393. Epub 2023 Apr 25 doi: 10.1055/a-2004-5330. PMID: 37164416
Clinical and histopathological features of conjunctival "Teddy bear" granuloma: A case series.
Lozano-Bustillo A, Ríos Y Valles-Valles D, Hernández-Ayuso I, Rodríguez-Reyes AA
Eur J Ophthalmol 2022 Nov;32(6):3674-3678. Epub 2022 Mar 1 doi: 10.1177/11206721221083135. PMID: 35230194
The case of the eyelid silicone granulomas.
Wulu JA, Garcia-Rodriguez L, Prilutskiy A, Spiegel JH
Am J Otolaryngol 2019 Sep-Oct;40(5):776-778. Epub 2019 May 14 doi: 10.1016/j.amjoto.2019.05.010. PMID: 31133360
Foreign-body granuloma of the penis in sexually active individuals (penile paraffinoma).
Pehlivanov G, Kavaklieva S, Kazandjieva J, Kapnilov D, Tsankov N
J Eur Acad Dermatol Venereol 2008 Jul;22(7):845-51. Epub 2008 Mar 19 doi: 10.1111/j.1468-3083.2008.02677.x. PMID: 18355202

Clinical prediction guides

Characterization of innate and adaptive immune cells involved in the foreign body reaction to polypropylene meshes in the human abdomen.
Dievernich A, Achenbach P, Davies L, Klinge U
Hernia 2022 Feb;26(1):309-323. Epub 2021 Mar 31 doi: 10.1007/s10029-021-02396-7. PMID: 33788008Free PMC Article
Morphological features of pilonidal cysts of the sacrococcygeal region.
Feleshtynskyi Y, Balan I, Dyadyk O, Beketova J
Pol Przegl Chir 2021 Jun 21;94(1):20-27. doi: 10.5604/01.3001.0015.7694. PMID: 35195080
A peritoneal defect covered by intraperitoneal mesh prosthesis effects an increased and distinctive foreign body reaction in a minipig model.
Eickhoff RM, Kroh A, Eickhoff S, Heise D, Helmedag MJ, Tolba RH, Klinge U, Neumann UP, Klink CD, Lambertz A
J Biomater Appl 2021 Jan;35(6):732-739. Epub 2020 Oct 8 doi: 10.1177/0885328220963918. PMID: 33331198
Activation of Herpes Simplex Infection after Tattoo.
Begolli Gerqari A, Ferizi M, Kotori M, Daka A, Hapciu S, Begolli I, Begolli M, Gerqari I
Acta Dermatovenerol Croat 2018 Apr;26(1):75-76. PMID: 29782308
Clinical outcome in a series of 173 cases of foreign body granuloma: improved outcomes with a novel surgical technique.
Park TH, Seo SW, Kim JK, Chang CH
J Plast Reconstr Aesthet Surg 2012 Jan;65(1):29-34. Epub 2011 Aug 31 doi: 10.1016/j.bjps.2011.07.033. PMID: 21885359

Recent systematic reviews

Cyanoacrylate glue reactions: A systematic review, cases, and proposed mechanisms.
Athavale A, Thao M, Sassaki VS, Lewis M, Chandra V, Fukaya E
J Vasc Surg Venous Lymphat Disord 2023 Jul;11(4):876-888.e1. Epub 2023 Apr 11 doi: 10.1016/j.jvsv.2023.03.018. PMID: 37054883
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review.
Machado RA, Oliveira LQ, Martelli-Júnior H, Pires FR, Carvas JB, Rogerio VE, Rabelo VD, Coletta RD
Med Oral Patol Oral Cir Bucal 2023 May 1;28(3):e278-e284. doi: 10.4317/medoral.25713. PMID: 36565218Free PMC Article
Foreign Body Granuloma After Cranial Surgery: A Systematic Review of Reported Cases.
Akhaddar A, Turgut AT, Turgut M
World Neurosurg 2018 Dec;120:457-475. Epub 2018 Sep 27 doi: 10.1016/j.wneu.2018.09.143. PMID: 30267951
Intracranial foreign material granulomas after cranial surgery.
Al-Afif S, Hatipoglu Majernik G, Hermann EJ, Esmaeilzadeh M, Hartmann C, Krauss JK
Acta Neurochir (Wien) 2018 Nov;160(11):2069-2075. Epub 2018 Sep 6 doi: 10.1007/s00701-018-3663-0. PMID: 30187219
Orbital Approaches for Treatment of Carotid Cavernous Fistulas: A Systematic Review.
Phan K, Xu J, Leung V, Teng I, Sheik-Ali S, Maharaj M, Mobbs R, Rao PJ
World Neurosurg 2016 Dec;96:243-251. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.087. PMID: 27586179

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