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Epidural hemorrhage

MedGen UID:
66764
Concept ID:
C0238154
Finding; Pathologic Function
Synonyms: Cranial Epidural Hematoma; Cranial Epidural Hematomas; Cranial Epidural Hemorrhage; Cranial Epidural Hemorrhages; Cranial Extradural Hematoma; Cranial Extradural Hematomas; Cranial Extradural Hemorrhage; Cranial Extradural Hemorrhages; Epidural Hematoma, Cranial; Epidural Hematoma, Intracranial; Epidural Hematomas, Cranial; Epidural Hematomas, Intracranial; Epidural Hemorrhage, Cranial; Epidural Hemorrhages, Cranial; Extradural Hematoma, Cranial; Extradural Hematomas, Cranial; Extradural Hemorrhage, Cranial; Extradural Hemorrhages, Cranial; Hematoma, Cranial Epidural; Hematoma, Cranial Extradural; Hematoma, Epidural, Cranial; Hematoma, Epidural, Intracranial; Hematoma, Intracranial Epidural; Hematomas, Cranial Epidural; Hematomas, Cranial Extradural; Hematomas, Intracranial Epidural; Hemorrhage, Cranial Epidural; Hemorrhage, Cranial Extradural; Hemorrhages, Cranial Epidural; Hemorrhages, Cranial Extradural; Intracranial Epidural Hematoma; Intracranial Epidural Hematomas
SNOMED CT: Epidural hemorrhage (82999001); Extradural hemorrhage (82999001); Extradural hematoma (428268007); Epidural intracranial hematoma (428268007); Epidural intracranial hemorrhage (82999001); Extradural intracranial hematoma (428268007)
 
HPO: HP:0100310

Definition

Hemorrhage occurring between the dura mater and the skull. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidural hemorrhage

Conditions with this feature

Congenital afibrinogenemia
MedGen UID:
749036
Concept ID:
C2584774
Disease or Syndrome
Inherited disorders of fibrinogen affect either the quantity (afibrinogenemia and hypofibrinogenemia; 202400) or the quality (dysfibrinogenemia; 616004) of the circulating fibrinogen or both (hypodysfibrinogenemia; see 616004). Afibrinogenemia is characterized by the complete absence of immunoreactive fibrinogen. Bleeding due to afibrinogenemia usually manifests in the neonatal period, with 85% of cases presenting umbilical cord bleeding, but a later age of onst is not unusual. Bleeding may occur in the skin, gastrointestinal tract, genitourinary tract, or the central nervous system, with intracranial hemorrhage being reported as the major cause of death. Patients are susceptible to spontaneous rupture of the spleen. Menstruating women may experience menometrorrhagia. First-trimester abortion is common. Both arterial and venous thromboembolic complications have been reported (summary by de Moerloose and Neerman-Arbez, 2009). Hypofibrinogenemia is characterized by reduced amounts of immunoreactive fibrinogen. Patients are often heterozygous carriers of afibrinogenemia mutations and are usually asymptomatic. However, they may bleed when exposed to trauma or if they have a second associated hemostatic abnormality. Women may experience miscarriages. Liver disease occurs in rare cases (summary by de Moerloose and Neerman-Arbez, 2009).
VISS syndrome
MedGen UID:
1794165
Concept ID:
C5561955
Disease or Syndrome
VISS syndrome is a generalized connective tissue disorder characterized by early-onset thoracic aortic aneurysm and other connective tissue findings, such as aneurysm and tortuosity of other arteries, joint hypermobility, skin laxity, and hernias, as well as craniofacial dysmorphic features, structural cardiac defects, skeletal anomalies, and motor developmental delay (Van Gucht et al., 2021). Immune dysregulation has been observed in some patients (Ziegler et al., 2021).

Professional guidelines

PubMed

Liao Y, Tian Y, Ye R, Tang C, Tang Q, Ma F, Yang S, He H, Zhong D
Medicine (Baltimore) 2020 Jan;99(2):e18711. doi: 10.1097/MD.0000000000018711. PMID: 31914081Free PMC Article
Samples DC, Bounajem MT, Wallace DJ, Liao L, Tarasiewicz I
Childs Nerv Syst 2019 Nov;35(11):2195-2203. Epub 2019 Jun 8 doi: 10.1007/s00381-019-04236-7. PMID: 31177323
Abou-Al-Shaar H, Gozal YM, Alzhrani G, Karsy M, Shelton C, Couldwell WT
Neurosurg Focus 2018 Jul;45(1):E4. doi: 10.3171/2018.4.FOCUS18112. PMID: 29961375

Recent clinical studies

Etiology

Agashe S, Brinkmann BH, Cox BC, Wong-Kisiel L, Van Gompel JJ, Marsh RW, Miller KJ, Krecke KN, Britton JW
Clin Neurophysiol 2023 Nov;155:86-93. Epub 2023 Sep 6 doi: 10.1016/j.clinph.2023.08.016. PMID: 37806180
Chen L, Li J, Huang S, Ma J, Zhou L
J Plast Reconstr Aesthet Surg 2023 Sep;84:71-78. Epub 2023 May 18 doi: 10.1016/j.bjps.2023.05.019. PMID: 37327735
Hirschmann D, Kranawetter B, Kirchschlager C, Tomschik M, Wais J, Winter F, Millesi M, Herta J, Roessler K, Dorfer C
Acta Neurochir (Wien) 2021 Feb;163(2):441-446. Epub 2020 Oct 3 doi: 10.1007/s00701-020-04597-y. PMID: 33009932Free PMC Article
Domenicucci M, Mancarella C, Santoro G, Dugoni DE, Ramieri A, Arezzo MF, Missori P
J Neurosurg Spine 2017 Aug;27(2):198-208. Epub 2017 Jun 2 doi: 10.3171/2016.12.SPINE15475. PMID: 28574329
Zuckerman SL, Morgan CD, Burks S, Forbes JA, Chambless LB, Solomon GS, Sills AK
World Neurosurg 2015 Jun;83(6):1098-113. Epub 2014 Dec 19 doi: 10.1016/j.wneu.2014.12.030. PMID: 25535066

Diagnosis

Neves G, Warman PI, Warman A, Warman R, Bueso T, Vadhan JD, Windisch T
World Neurosurg 2023 May;173:e800-e807. Epub 2023 Mar 9 doi: 10.1016/j.wneu.2023.03.019. PMID: 36906085
Özdöl Ç, Gediz T, Aghayev K
Ulus Travma Acil Cerrahi Derg 2019 Mar;25(2):167-171. doi: 10.14744/tjtes.2019.46116. PMID: 30892669
Shaban A, Moritani T, Al Kasab S, Sheharyar A, Limaye KS, Adams HP Jr
J Stroke Cerebrovasc Dis 2018 Jun;27(6):1435-1446. Epub 2018 Mar 16 doi: 10.1016/j.jstrokecerebrovasdis.2018.02.014. PMID: 29555403
Piteau SJ, Ward MG, Barrowman NJ, Plint AC
Pediatrics 2012 Aug;130(2):315-23. Epub 2012 Jul 9 doi: 10.1542/peds.2011-1545. PMID: 22778309
Connolly ES Jr, Winfree CJ, McCormick PC
Spine (Phila Pa 1976) 1996 Jul 15;21(14):1694-8. doi: 10.1097/00007632-199607150-00016. PMID: 8839474

Therapy

Chen L, Li J, Huang S, Ma J, Zhou L
J Plast Reconstr Aesthet Surg 2023 Sep;84:71-78. Epub 2023 May 18 doi: 10.1016/j.bjps.2023.05.019. PMID: 37327735
Yüce I, Kahyaoğlu O, Çavuşoğlu H, Kara S, Aydın Y
Neurochirurgie 2021 Jul;67(4):362-368. Epub 2020 Nov 21 doi: 10.1016/j.neuchi.2020.10.009. PMID: 33232714
Hung SL, Chen CY, Chin WL, Lee CH, Chen JH
Langenbecks Arch Surg 2021 Feb;406(1):189-196. Epub 2020 Nov 10 doi: 10.1007/s00423-020-02027-2. PMID: 33174167
Hirschmann D, Kranawetter B, Kirchschlager C, Tomschik M, Wais J, Winter F, Millesi M, Herta J, Roessler K, Dorfer C
Acta Neurochir (Wien) 2021 Feb;163(2):441-446. Epub 2020 Oct 3 doi: 10.1007/s00701-020-04597-y. PMID: 33009932Free PMC Article
Connolly ES Jr, Winfree CJ, McCormick PC
Spine (Phila Pa 1976) 1996 Jul 15;21(14):1694-8. doi: 10.1097/00007632-199607150-00016. PMID: 8839474

Prognosis

Agashe S, Brinkmann BH, Cox BC, Wong-Kisiel L, Van Gompel JJ, Marsh RW, Miller KJ, Krecke KN, Britton JW
Clin Neurophysiol 2023 Nov;155:86-93. Epub 2023 Sep 6 doi: 10.1016/j.clinph.2023.08.016. PMID: 37806180
Zhang JY, Li Y, Ma YS, Sun XJ, Liu YZ, Yin YK, Hu B, Su MH, Li QL, Mi YC, Li DP
Ann Hematol 2022 Dec;101(12):2617-2625. Epub 2022 Sep 30 doi: 10.1007/s00277-022-04982-w. PMID: 36178488Free PMC Article
Hirschmann D, Kranawetter B, Kirchschlager C, Tomschik M, Wais J, Winter F, Millesi M, Herta J, Roessler K, Dorfer C
Acta Neurochir (Wien) 2021 Feb;163(2):441-446. Epub 2020 Oct 3 doi: 10.1007/s00701-020-04597-y. PMID: 33009932Free PMC Article
Shaban A, Moritani T, Al Kasab S, Sheharyar A, Limaye KS, Adams HP Jr
J Stroke Cerebrovasc Dis 2018 Jun;27(6):1435-1446. Epub 2018 Mar 16 doi: 10.1016/j.jstrokecerebrovasdis.2018.02.014. PMID: 29555403
Piteau SJ, Ward MG, Barrowman NJ, Plint AC
Pediatrics 2012 Aug;130(2):315-23. Epub 2012 Jul 9 doi: 10.1542/peds.2011-1545. PMID: 22778309

Clinical prediction guides

Chen L, Li J, Huang S, Ma J, Zhou L
J Plast Reconstr Aesthet Surg 2023 Sep;84:71-78. Epub 2023 May 18 doi: 10.1016/j.bjps.2023.05.019. PMID: 37327735
Özdöl Ç, Gediz T, Aghayev K
Ulus Travma Acil Cerrahi Derg 2019 Mar;25(2):167-171. doi: 10.14744/tjtes.2019.46116. PMID: 30892669
Wang H, Zhou Y, Liu J, Ou L, Han J, Xiang L
Injury 2018 Feb;49(2):219-225. Epub 2017 Nov 29 doi: 10.1016/j.injury.2017.11.039. PMID: 29203200
Zhao Q, Zhong E, Shi B, Li Y, Sun C, Ding Z
Spine J 2016 Aug;16(8):1001-6. Epub 2016 Apr 6 doi: 10.1016/j.spinee.2016.03.048. PMID: 27060710
Shi B, Li X, Li H, Ding Z
Spine (Phila Pa 1976) 2012 Aug 15;37(18):E1093-8. doi: 10.1097/BRS.0b013e31825c05ea. PMID: 22565391

Recent systematic reviews

Peng J, Luo T, Li X, Li B, Cheng Y, Huang Q, Su J
Sci Rep 2024 Mar 12;14(1):5961. doi: 10.1038/s41598-024-56232-w. PMID: 38472247Free PMC Article
Zuckerman SL, Yengo-Kahn AM, Tang AR, Bailes JE, Beauchamp K, Berger MS, Bonfield CM, Camarata PJ, Cantu RC, Davis GA, Ellenbogen RG, Ellis MJ, Feuer H, Guazzo E, Harris OA, Heppner P, Honeybul S, Manley G, Maroon JC, Miele VJ, Nahed BV, Okonkwo DO, Oppenlander ME, Petty J, Sabin HI, Samadani U, Sherburn EW, Sheridan M, Tator CH, Theodore N, Timmons SD, Woodworth GF, Solomon GS, Sills AK
Neurosurgery 2021 May 13;88(6):E495-E504. doi: 10.1093/neuros/nyab041. PMID: 33693899
Piteau SJ, Ward MG, Barrowman NJ, Plint AC
Pediatrics 2012 Aug;130(2):315-23. Epub 2012 Jul 9 doi: 10.1542/peds.2011-1545. PMID: 22778309

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