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Vaginal clear cell adenocarcinoma

MedGen UID:
66774
Concept ID:
C0238517
Neoplastic Process
Synonyms: Clear cell adenocarcinoma of the vagina; Clear Cell Adenocarcinoma of the Vagina; Clear Cell Adenocarcinoma of Vagina; Vagina Clear Cell Adenocarcinoma; Vaginal Clear Cell Adenocarcinoma
 
HPO: HP:0031521

Definition

A type of adenocarcinoma originating in the vagina and characterized by large cells with moderate to abundant clear cytoplasm. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal clear cell adenocarcinoma

Professional guidelines

PubMed

Talia KL, Wong RW, McCluggage WG
Int J Gynecol Pathol 2019 May;38(3):276-282. doi: 10.1097/PGP.0000000000000529. PMID: 29901522
Hong JC, Foote J, Broadwater G, Gaillard S, Havrilesky LJ, Chino JP
Int J Gynecol Cancer 2017 May;27(4):720-729. doi: 10.1097/IGC.0000000000000926. PMID: 28375927
Huang HJ, Tang YH, Chou HH, Yang LY, Chao A, Huang YT, Lin G, Liu FY, Chang TC, Lai CH
Int J Gynecol Cancer 2014 Jun;24(5):885-93. doi: 10.1097/IGC.0000000000000131. PMID: 24819657

Recent clinical studies

Etiology

Tournaire M, Gondry J, Mauny L, Devouche E, Morice P
J Gynecol Obstet Hum Reprod 2023 Oct;52(8):102630. Epub 2023 Jul 13 doi: 10.1016/j.jogoh.2023.102630. PMID: 37451413
Conlon JL
JAAPA 2017 Feb;30(2):49-52. doi: 10.1097/01.JAA.0000511800.91372.34. PMID: 28098674
Magné N, Chargari C, Levy A, Rodriguez C, De Vos V, Gerbaulet A, Duvillard P, Morice P, Haie-Meder C
Int J Gynecol Cancer 2012 Oct;22(8):1378-82. doi: 10.1097/IGC.0b013e318264a51d. PMID: 22932263
Senekjian EK, Frey KW, Stone C, Herbst AL
Gynecol Oncol 1988 Sep;31(1):56-64. doi: 10.1016/0090-8258(88)90269-7. PMID: 3410356
Sander R, Nuss RC, Rhatigan RM
Int J Gynecol Pathol 1986;5(4):362-70. doi: 10.1097/00004347-198612000-00008. PMID: 3643169

Diagnosis

Tournaire M, Gondry J, Mauny L, Devouche E, Morice P
J Gynecol Obstet Hum Reprod 2023 Oct;52(8):102630. Epub 2023 Jul 13 doi: 10.1016/j.jogoh.2023.102630. PMID: 37451413
Alipour P, Arjmandi K, Hallaji F
Pediatr Hematol Oncol 2008 Sep;25(7):679-84. doi: 10.1080/08880010802313723. PMID: 18850481
Waggoner SE, Mittendorf R, Biney N, Anderson D, Herbst AL
Gynecol Oncol 1994 Nov;55(2):238-44. doi: 10.1006/gyno.1994.1284. PMID: 7959291
Sharp GB, Cole P, Anderson D, Herbst AL
Cancer 1990 Nov 15;66(10):2215-20. doi: 10.1002/1097-0142(19901115)66:10<2215::aid-cncr2820661029>3.0.co;2-q. PMID: 2224777
Sander R, Nuss RC, Rhatigan RM
Int J Gynecol Pathol 1986;5(4):362-70. doi: 10.1097/00004347-198612000-00008. PMID: 3643169

Therapy

Tournaire M, Gondry J, Mauny L, Devouche E, Morice P
J Gynecol Obstet Hum Reprod 2023 Oct;52(8):102630. Epub 2023 Jul 13 doi: 10.1016/j.jogoh.2023.102630. PMID: 37451413
Conlon JL
JAAPA 2017 Feb;30(2):49-52. doi: 10.1097/01.JAA.0000511800.91372.34. PMID: 28098674
Harris RM, Waring RH
Maturitas 2012 Jun;72(2):108-12. Epub 2012 Mar 29 doi: 10.1016/j.maturitas.2012.03.002. PMID: 22464649
Sharp GB, Cole P, Anderson D, Herbst AL
Cancer 1990 Nov 15;66(10):2215-20. doi: 10.1002/1097-0142(19901115)66:10<2215::aid-cncr2820661029>3.0.co;2-q. PMID: 2224777
Sander R, Nuss RC, Rhatigan RM
Int J Gynecol Pathol 1986;5(4):362-70. doi: 10.1097/00004347-198612000-00008. PMID: 3643169

Prognosis

Magné N, Chargari C, Levy A, Rodriguez C, De Vos V, Gerbaulet A, Duvillard P, Morice P, Haie-Meder C
Int J Gynecol Cancer 2012 Oct;22(8):1378-82. doi: 10.1097/IGC.0b013e318264a51d. PMID: 22932263
Trimble EL, Rubinstein LV, Menck HR, Hankey BF, Kosary C, Giusti RM
Gynecol Oncol 1996 Apr;61(1):113-5. doi: 10.1006/gyno.1996.0107. PMID: 8626097
Waggoner SE, Mittendorf R, Biney N, Anderson D, Herbst AL
Gynecol Oncol 1994 Nov;55(2):238-44. doi: 10.1006/gyno.1994.1284. PMID: 7959291
Senekjian EK, Frey KW, Anderson D, Herbst AL
Cancer 1987 Sep 15;60(6):1319-24. doi: 10.1002/1097-0142(19870915)60:6<1319::aid-cncr2820600626>3.0.co;2-h. PMID: 3621114
Blythe JG, Michael H, Hodel KA
J Reprod Med 1983 Feb;28(2):137-46. PMID: 6834354

Clinical prediction guides

Tournaire M, Gondry J, Mauny L, Devouche E, Morice P
J Gynecol Obstet Hum Reprod 2023 Oct;52(8):102630. Epub 2023 Jul 13 doi: 10.1016/j.jogoh.2023.102630. PMID: 37451413
Magné N, Chargari C, Levy A, Rodriguez C, De Vos V, Gerbaulet A, Duvillard P, Morice P, Haie-Meder C
Int J Gynecol Cancer 2012 Oct;22(8):1378-82. doi: 10.1097/IGC.0b013e318264a51d. PMID: 22932263
Blythe JG, Michael H, Hodel KA
J Reprod Med 1983 Feb;28(2):137-46. PMID: 6834354
Netzloff ML
Ann Clin Lab Sci 1979 Jul-Aug;9(4):263-7. PMID: 485089

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