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Vaginal squamous cell carcinoma

MedGen UID:
66775
Concept ID:
C0238518
Neoplastic Process
Synonyms: carcinoma of vagina squamous cell; epidermoid carcinoma of the vagina; epidermoid carcinoma of vagina; epidermoid cell carcinoma of the vagina; epidermoid cell carcinoma of vagina; Squamous cell cancer of vagina; squamous cell carcinoma of the vagina; squamous cell carcinoma of the vulva/vagina; Squamous cell carcinoma of vagina; squamous cell carcinoma of vagina; vagina epidermoid carcinoma; vagina epidermoid cell carcinoma; vagina squamous cell carcinoma; vaginal epidermoid carcinoma; vaginal epidermoid cell carcinoma; vaginal squamous cell cancer; vaginal squamous cell cancer, NOS; Vaginal Squamous Cell Carcinoma; vaginal squamous cell carcinoma; Vaginal Squamous Cell Carcinoma, NOS; Vaginal Squamous Cell Carcinoma, Not Otherwise Specified
SNOMED CT: Squamous cell carcinoma of vagina (105121000119102); Squamous cell cancer of vagina (105121000119102)
 
Monarch Initiative: MONDO:0006490

Definition

Vaginal squamous cell carcinoma in which information on the p16 immunohistochemistry or HPV testing status is not available. [from NCI]

Professional guidelines

PubMed

Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Yang J, Delara R, Magrina J, Magtibay P, Langstraat C, Dinh T, Karlin N, Vora SA, Butler K
Gynecol Oncol 2020 Nov;159(2):456-463. Epub 2020 Sep 22 doi: 10.1016/j.ygyno.2020.08.036. PMID: 32972784
Shrivastava SB, Agrawal G, Mittal M, Mishra P
Rev Recent Clin Trials 2015;10(4):289-97. doi: 10.2174/1574887110666150923112958. PMID: 26411952

Recent clinical studies

Etiology

Romano E, Janati S, Monnier L, Darai É, Bendifallah S, Schlienger M, Touboul E, Rivin Del Campo E, Huguet F
Clin Transl Oncol 2020 Aug;22(8):1345-1354. Epub 2019 Dec 23 doi: 10.1007/s12094-019-02264-y. PMID: 31873914
Lima M, Rio G, Horta M, Cunha TM
J Obstet Gynaecol 2019 Aug;39(6):827-832. Epub 2019 Apr 25 doi: 10.1080/01443615.2019.1579786. PMID: 31020870
Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Ghezelayagh T, Rauh-Hain JA, Growdon WB
Obstet Gynecol 2015 Jun;125(6):1353-1361. doi: 10.1097/AOG.0000000000000861. PMID: 26000506
Lee YC, Holcomb K, Buhl A, Holden J, Abulafia O
Gynecol Oncol 2000 Sep;78(3 Pt 1):380-2. doi: 10.1006/gyno.2000.5924. PMID: 10985898

Diagnosis

Shen Y, Meng X, Wang L, Wang X, Chang H
Front Immunol 2022;13:1007462. Epub 2022 Nov 22 doi: 10.3389/fimmu.2022.1007462. PMID: 36483563Free PMC Article
Bertoli HK, Baandrup L, Aalborg GL, Kjaer AK, Thomsen LT, Kjaer SK
Gynecol Oncol 2020 Sep;158(3):734-739. Epub 2020 Jun 19 doi: 10.1016/j.ygyno.2020.05.683. PMID: 32571683
Lima M, Rio G, Horta M, Cunha TM
J Obstet Gynaecol 2019 Aug;39(6):827-832. Epub 2019 Apr 25 doi: 10.1080/01443615.2019.1579786. PMID: 31020870
Lee YC, Holcomb K, Buhl A, Holden J, Abulafia O
Gynecol Oncol 2000 Sep;78(3 Pt 1):380-2. doi: 10.1006/gyno.2000.5924. PMID: 10985898
Raptis S, Haber G, Ferenczy A
Gynecol Oncol 1993 Apr;49(1):100-6. doi: 10.1006/gyno.1993.1094. PMID: 8482552

Therapy

Romano E, Janati S, Monnier L, Darai É, Bendifallah S, Schlienger M, Touboul E, Rivin Del Campo E, Huguet F
Clin Transl Oncol 2020 Aug;22(8):1345-1354. Epub 2019 Dec 23 doi: 10.1007/s12094-019-02264-y. PMID: 31873914
Bertoli HK, Rasmussen CL, Sand FL, Albieri V, Norrild B, Verdoodt F, Kjaer SK
Int J Cancer 2019 Jul 1;145(1):78-86. Epub 2019 Jan 11 doi: 10.1002/ijc.32078. PMID: 30561092
Laliscia C, Gadducci A, Fabrini MG, Barcellini A, Guerrieri ME, Parietti E, Ursino S, Morganti R, Cafaro I, Paiar F
Oncol Res Treat 2017;40(11):697-701. Epub 2017 Oct 20 doi: 10.1159/000480350. PMID: 29065399
Mabuchi Y, Yahata T, Kobayashi A, Tanizaki Y, Minami S, Ino K
J Obstet Gynaecol Res 2015 Jun;41(6):989-92. Epub 2014 Dec 16 doi: 10.1111/jog.12638. PMID: 25512111
de Crevoisier R, Sanfilippo N, Gerbaulet A, Morice P, Pomel C, Castaigne D, Pautier P, Lhomme C, Duvillard P, Haie-meder C
Radiother Oncol 2007 Dec;85(3):362-70. Epub 2007 Oct 25 doi: 10.1016/j.radonc.2007.09.015. PMID: 17963909

Prognosis

Bertoli HK, Baandrup L, Aalborg GL, Kjaer AK, Thomsen LT, Kjaer SK
Gynecol Oncol 2020 Sep;158(3):734-739. Epub 2020 Jun 19 doi: 10.1016/j.ygyno.2020.05.683. PMID: 32571683
Romano E, Janati S, Monnier L, Darai É, Bendifallah S, Schlienger M, Touboul E, Rivin Del Campo E, Huguet F
Clin Transl Oncol 2020 Aug;22(8):1345-1354. Epub 2019 Dec 23 doi: 10.1007/s12094-019-02264-y. PMID: 31873914
Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Ghezelayagh T, Rauh-Hain JA, Growdon WB
Obstet Gynecol 2015 Jun;125(6):1353-1361. doi: 10.1097/AOG.0000000000000861. PMID: 26000506
de Crevoisier R, Sanfilippo N, Gerbaulet A, Morice P, Pomel C, Castaigne D, Pautier P, Lhomme C, Duvillard P, Haie-meder C
Radiother Oncol 2007 Dec;85(3):362-70. Epub 2007 Oct 25 doi: 10.1016/j.radonc.2007.09.015. PMID: 17963909

Clinical prediction guides

Bertoli HK, Baandrup L, Aalborg GL, Kjaer AK, Thomsen LT, Kjaer SK
Gynecol Oncol 2020 Sep;158(3):734-739. Epub 2020 Jun 19 doi: 10.1016/j.ygyno.2020.05.683. PMID: 32571683
Bertoli HK, Rasmussen CL, Sand FL, Albieri V, Norrild B, Verdoodt F, Kjaer SK
Int J Cancer 2019 Jul 1;145(1):78-86. Epub 2019 Jan 11 doi: 10.1002/ijc.32078. PMID: 30561092
Di Domenico A
Gynecol Oncol 1989 Nov;35(2):181-7. doi: 10.1016/0090-8258(89)90040-1. PMID: 2680798

Recent systematic reviews

Bertoli HK, Rasmussen CL, Sand FL, Albieri V, Norrild B, Verdoodt F, Kjaer SK
Int J Cancer 2019 Jul 1;145(1):78-86. Epub 2019 Jan 11 doi: 10.1002/ijc.32078. PMID: 30561092

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