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Benign Skull Neoplasm

MedGen UID:
671540
•Concept ID:
C0684517
•
Neoplastic Process
Synonym: Benign neoplasm of bone of skull
SNOMED CT: Benign neoplasm of bone of skull (92025003)

Definition

A neoplasm that arises from the bones and structures of skull and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.
Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Ameloblastoma: current etiopathological concepts and management.
Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

Recent clinical studies

Etiology

Surgical management of skull base meningiomas and vestibular schwannomas.
Gambacciani C, Grimod G, Sameshima T, Santonocito OS
Curr Opin Oncol 2022 Nov 1;34(6):713-722. Epub 2022 Sep 7 doi: 10.1097/CCO.0000000000000904. PMID: 36093884
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Sinonasal seromucinous hamartoma.
Huang YW, Kuo YJ, Ho CY, Lan MY
Eur Arch Otorhinolaryngol 2018 Mar;275(3):743-749. Epub 2018 Jan 30 doi: 10.1007/s00405-018-4885-8. PMID: 29380040
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455
Ameloblastoma.
Mendenhall WM, Werning JW, Fernandes R, Malyapa RS, Mendenhall NP
Am J Clin Oncol 2007 Dec;30(6):645-8. doi: 10.1097/COC.0b013e3181573e59. PMID: 18091060

Diagnosis

Imaging of Skull Base Tumors.
Battal B, Zamora C
Tomography 2023 Jun 21;9(4):1196-1235. doi: 10.3390/tomography9040097. PMID: 37489465Free PMC Article
Skull Base Tumor Mimics.
Huang JH, Hagiwara M
Neuroimaging Clin N Am 2022 May;32(2):327-344. doi: 10.1016/j.nic.2022.02.001. PMID: 35526960
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Ameloblastoma-Clinical, radiological, and therapeutic findings.
Kreppel M, Zöller J
Oral Dis 2018 Mar;24(1-2):63-66. doi: 10.1111/odi.12702. PMID: 29480593
Ameloblastoma: current etiopathological concepts and management.
Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

Therapy

Management of osteosarcoma of the head and neck.
Sharin F, Pai A, Mair M
Curr Opin Otolaryngol Head Neck Surg 2023 Aug 1;31(4):269-275. Epub 2023 May 3 doi: 10.1097/MOO.0000000000000900. PMID: 37144500
Innovative treatments for meningiomas.
Graillon T, Tabouret E, Salgues B, Horowitz T, Padovani L, Appay R, Farah K, Dufour H, Régis J, Guedj E, Barlier A, Chinot O
Rev Neurol (Paris) 2023 Jun;179(5):449-463. Epub 2023 Mar 21 doi: 10.1016/j.neurol.2023.03.006. PMID: 36959063
Tumor-Induced Osteomalacia.
Florenzano P, Hartley IR, Jimenez M, Roszko K, Gafni RI, Collins MT
Calcif Tissue Int 2021 Jan;108(1):128-142. Epub 2020 Jun 5 doi: 10.1007/s00223-020-00691-6. PMID: 32504138
Pediatric pituitary adenomas.
Walz PC, Drapeau A, Shaikhouni A, Eide J, Rugino AJ, Mohyeldin A, Carrau R, Prevedello D
Childs Nerv Syst 2019 Nov;35(11):2107-2118. Epub 2019 Jul 13 doi: 10.1007/s00381-019-04293-y. PMID: 31302729
Meningioma.
Marosi C, Hassler M, Roessler K, Reni M, Sant M, Mazza E, Vecht C
Crit Rev Oncol Hematol 2008 Aug;67(2):153-71. Epub 2008 Mar 14 doi: 10.1016/j.critrevonc.2008.01.010. PMID: 18342535

Prognosis

Surgical management of skull base meningiomas and vestibular schwannomas.
Gambacciani C, Grimod G, Sameshima T, Santonocito OS
Curr Opin Oncol 2022 Nov 1;34(6):713-722. Epub 2022 Sep 7 doi: 10.1097/CCO.0000000000000904. PMID: 36093884
Rare Diseases of the Orbit.
Kisser U, Heichel J, Glien A
Laryngorhinootologie 2021 Apr;100(S 01):S1-S79. Epub 2021 Apr 30 doi: 10.1055/a-1384-4641. PMID: 34352903Free PMC Article
Ameloblastoma-Clinical, radiological, and therapeutic findings.
Kreppel M, Zöller J
Oral Dis 2018 Mar;24(1-2):63-66. doi: 10.1111/odi.12702. PMID: 29480593
Sinonasal seromucinous hamartoma.
Huang YW, Kuo YJ, Ho CY, Lan MY
Eur Arch Otorhinolaryngol 2018 Mar;275(3):743-749. Epub 2018 Jan 30 doi: 10.1007/s00405-018-4885-8. PMID: 29380040
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Clinical prediction guides

Benign Tumors of the Anterior Cranial Base.
Snyderman CH, Lavigne P
Adv Otorhinolaryngol 2020;84:106-113. Epub 2020 Jul 30 doi: 10.1159/000457930. PMID: 32731223
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Orbital Paraganglioma.
Zhu B, Yan J
J Craniofac Surg 2019 Sep;30(6):e503-e506. doi: 10.1097/SCS.0000000000005408. PMID: 30896513
Orbital Metastases: When to Suspect? When to biopsy?
Allen RC
Middle East Afr J Ophthalmol 2018 Apr-Jun;25(2):60-64. doi: 10.4103/meajo.MEAJO_93_18. PMID: 30122850Free PMC Article
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Recent systematic reviews

Assessing survival outcomes and complication profiles following surgical excision and radiotherapy as interventions for skull base chordoma: a systematic review of operative margins and surgical approaches.
Brown NJ, Gendreau J, Kuo CC, Nguyen O, Yang C, Catapano JS, Lawton MT
J Neurooncol 2023 Oct;165(1):41-51. Epub 2023 Oct 25 doi: 10.1007/s11060-023-04477-2. PMID: 37880419
Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review.
Runge A, Randhawa A, Mayo-Patiño M, Santer M, Hartl R, Dejaco D, Eloy JA
Am J Rhinol Allergy 2023 Sep;37(5):586-592. Epub 2023 Apr 24 doi: 10.1177/19458924231170464. PMID: 37093753
Management of inverted papilloma: review.
Attlmayr B, Derbyshire SG, Kasbekar AV, Swift AC
J Laryngol Otol 2017 Apr;131(4):284-289. Epub 2017 Feb 9 doi: 10.1017/S0022215117000172. PMID: 28179032
Seizures in supratentorial meningioma: a systematic review and meta-analysis.
Englot DJ, Magill ST, Han SJ, Chang EF, Berger MS, McDermott MW
J Neurosurg 2016 Jun;124(6):1552-61. Epub 2015 Dec 4 doi: 10.3171/2015.4.JNS142742. PMID: 26636386Free PMC Article
Sinonasal and ventral skull base inflammatory pseudotumor: a systematic review.
Desai SV, Spinazzi EF, Fang CH, Huang G, Tomovic S, Liu JK, Baredes S, Eloy JA
Laryngoscope 2015 Apr;125(4):813-21. Epub 2014 Nov 6 doi: 10.1002/lary.24993. PMID: 25376630

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