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Brucellosis

MedGen UID:
674
Concept ID:
C0006309
Disease or Syndrome
Synonyms: Cyprus fever; Gibraltar fever; Malta fever; Rock fever; Undulant fever
SNOMED CT: Brucellosis (75702008); Malta fever (75702008); Mediterranean fever (75702008); Undulant fever (75702008); Cyprus fever (75702008); Rock fever (75702008); Gibraltar fever (75702008)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005683
Orphanet: ORPHA1304

Definition

Brucellosis is an anthropozoonotic infection, endemic in the Mediterranean region, the Middle East, Latin America and parts of Asia and Africa, that is caused by gram-negative coccobacilli of the genus <i>Brucella</i> transmitted through consumption of unpasteurized dairy products or through direct contact with infected animals, placentas or aborted fetuses. Brucellosis is characterized by fever, fatigue, malaise, headache, anorexia, weight loss, sweating, osteomuscular pain (joint and lumbar pain), and arthritis. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBrucellosis
Follow this link to review classifications for Brucellosis in Orphanet.

Professional guidelines

PubMed

Qureshi KA, Parvez A, Fahmy NA, Abdel Hady BH, Kumar S, Ganguly A, Atiya A, Elhassan GO, Alfadly SO, Parkkila S, Aspatwar A
Ann Med 2023;55(2):2295398. Epub 2024 Jan 2 doi: 10.1080/07853890.2023.2295398. PMID: 38165919Free PMC Article
Głowacka P, Żakowska D, Naylor K, Niemcewicz M, Bielawska-Drózd A
Pol J Microbiol 2018 Jun 30;67(2):151-161. doi: 10.21307/pjm-2018-029. PMID: 30015453Free PMC Article
Pappas G
BMJ 2008 Mar 29;336(7646):678-9. Epub 2008 Mar 5 doi: 10.1136/bmj.39497.431528.80. PMID: 18321958Free PMC Article

Recent clinical studies

Etiology

Djokic V, Freddi L, de Massis F, Lahti E, van den Esker MH, Whatmore A, Haughey A, Ferreira AC, Garofolo G, Melzer F, Sacchini F, Koets A, Wyllie S, Fontbonne A, Girault G, Vicente AF, McGiven J, Ponsart C
Emerg Microbes Infect 2023 Dec;12(2):2249126. Epub 2023 Aug 31 doi: 10.1080/22221751.2023.2249126. PMID: 37649455Free PMC Article
Laine CG, Johnson VE, Scott HM, Arenas-Gamboa AM
Emerg Infect Dis 2023 Sep;29(9):1789-1797. doi: 10.3201/eid2909.230052. PMID: 37610167Free PMC Article
Bouferraa Y, Bou Zerdan M, Hamouche R, Azar E, Afif C, Jabbour R
Neurologist 2021 Nov 4;26(6):248-252. doi: 10.1097/NRL.0000000000000348. PMID: 34734902
Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV
Lancet Infect Dis 2006 Feb;6(2):91-9. doi: 10.1016/S1473-3099(06)70382-6. PMID: 16439329
Jeroudi MO, Halim MA, Harder EJ, Al-Siba'i MB, Ziady G, Mercer EN
Br Heart J 1987 Sep;58(3):279-83. doi: 10.1136/hrt.58.3.279. PMID: 3311098Free PMC Article

Diagnosis

Jin M, Fan Z, Gao R, Li X, Gao Z, Wang Z
Front Cell Infect Microbiol 2023;13:1136674. Epub 2023 Mar 31 doi: 10.3389/fcimb.2023.1136674. PMID: 37065189Free PMC Article
Crecelius EM, Burnett MW
J Spec Oper Med 2021 Summer;21(2):98-99. doi: 10.55460/QMQR-TI7J. PMID: 34105131
Khurana SK, Sehrawat A, Tiwari R, Prasad M, Gulati B, Shabbir MZ, Chhabra R, Karthik K, Patel SK, Pathak M, Iqbal Yatoo M, Gupta VK, Dhama K, Sah R, Chaicumpa W
Vet Q 2021 Jan 1;41(1):61-88. doi: 10.1080/01652176.2020.1868616. PMID: 33353489Free PMC Article
Tali ET, Koc AM, Oner AY
Neuroimaging Clin N Am 2015 May;25(2):233-45. doi: 10.1016/j.nic.2015.01.004. PMID: 25952175
Franco MP, Mulder M, Gilman RH, Smits HL
Lancet Infect Dis 2007 Dec;7(12):775-86. doi: 10.1016/S1473-3099(07)70286-4. PMID: 18045560

Therapy

Qureshi KA, Parvez A, Fahmy NA, Abdel Hady BH, Kumar S, Ganguly A, Atiya A, Elhassan GO, Alfadly SO, Parkkila S, Aspatwar A
Ann Med 2023;55(2):2295398. Epub 2024 Jan 2 doi: 10.1080/07853890.2023.2295398. PMID: 38165919Free PMC Article
Deng Y, Liu X, Duan K, Peng Q
Curr Med Chem 2019;26(30):5598-5608. doi: 10.2174/0929867325666180510125009. PMID: 29745323
Harrison ER, Posada R
Pediatr Rev 2018 Apr;39(4):222-224. doi: 10.1542/pir.2017-0126. PMID: 29610436
Tali ET, Koc AM, Oner AY
Neuroimaging Clin N Am 2015 May;25(2):233-45. doi: 10.1016/j.nic.2015.01.004. PMID: 25952175
Bouza E, García de la Torre M, Parras F, Guerrero A, Rodríguez-Créixems M, Gobernado J
Rev Infect Dis 1987 Jul-Aug;9(4):810-22. doi: 10.1093/clinids/9.4.810. PMID: 3326128

Prognosis

Laine CG, Johnson VE, Scott HM, Arenas-Gamboa AM
Emerg Infect Dis 2023 Sep;29(9):1789-1797. doi: 10.3201/eid2909.230052. PMID: 37610167Free PMC Article
Jin M, Fan Z, Gao R, Li X, Gao Z, Wang Z
Front Cell Infect Microbiol 2023;13:1136674. Epub 2023 Mar 31 doi: 10.3389/fcimb.2023.1136674. PMID: 37065189Free PMC Article
Zheng R, Xie S, Lu X, Sun L, Zhou Y, Zhang Y, Wang K
Biomed Res Int 2018;2018:5712920. Epub 2018 Apr 22 doi: 10.1155/2018/5712920. PMID: 29850535Free PMC Article
Bouza E, García de la Torre M, Parras F, Guerrero A, Rodríguez-Créixems M, Gobernado J
Rev Infect Dis 1987 Jul-Aug;9(4):810-22. doi: 10.1093/clinids/9.4.810. PMID: 3326128
Jeroudi MO, Halim MA, Harder EJ, Al-Siba'i MB, Ziady G, Mercer EN
Br Heart J 1987 Sep;58(3):279-83. doi: 10.1136/hrt.58.3.279. PMID: 3311098Free PMC Article

Clinical prediction guides

Arslan Y, Baran Aİ, Çelik M
Ir J Med Sci 2024 Feb;193(1):149-156. Epub 2023 May 16 doi: 10.1007/s11845-023-03382-x. PMID: 37191870
Giambartolomei GH, Delpino MV
Front Cell Infect Microbiol 2019;9:423. Epub 2019 Dec 20 doi: 10.3389/fcimb.2019.00423. PMID: 31956605Free PMC Article
Solera J, Solís García Del Pozo J
Expert Rev Anti Infect Ther 2017 Jan;15(1):33-42. Epub 2016 Nov 10 doi: 10.1080/14787210.2017.1254042. PMID: 27790937
Arkun R, Mete BD
Semin Musculoskelet Radiol 2011 Nov;15(5):470-9. Epub 2011 Nov 11 doi: 10.1055/s-0031-1293493. PMID: 22081282
Bodur H, Erbay A, Colpan A, Akinci E
Rheumatol Int 2004 Jul;24(4):221-6. Epub 2003 Jul 16 doi: 10.1007/s00296-003-0350-z. PMID: 12879273

Recent systematic reviews

Alsaif M, Dabelah K, Girim H, Featherstone R, Robinson JL
Vector Borne Zoonotic Dis 2018 Aug;18(8):393-403. Epub 2018 Jun 29 doi: 10.1089/vbz.2018.2280. PMID: 29957148
Zheng R, Xie S, Lu X, Sun L, Zhou Y, Zhang Y, Wang K
Biomed Res Int 2018;2018:5712920. Epub 2018 Apr 22 doi: 10.1155/2018/5712920. PMID: 29850535Free PMC Article
Mirnejad R, Jazi FM, Mostafaei S, Sedighi M
Microb Pathog 2017 Aug;109:239-247. Epub 2017 Jun 7 doi: 10.1016/j.micpath.2017.06.005. PMID: 28602839
Solera J, Solís García Del Pozo J
Expert Rev Anti Infect Ther 2017 Jan;15(1):33-42. Epub 2016 Nov 10 doi: 10.1080/14787210.2017.1254042. PMID: 27790937
Musallam II, Abo-Shehada MN, Hegazy YM, Holt HR, Guitian FJ
Epidemiol Infect 2016 Mar;144(4):671-85. Epub 2015 Oct 28 doi: 10.1017/S0950268815002575. PMID: 26508323

Supplemental Content

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