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Painful mouth

MedGen UID:
67463
•Concept ID:
C0221776
•
Sign or Symptom
Synonyms: Oral Pain; Oral pain
SNOMED CT: Painful mouth (102616008); Oral pain (102616008)

Definition

Painful sensation in the mouth, tongue, or lips. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPainful mouth

Professional guidelines

PubMed

Temporomandibular disorder and generalized joint hypermobility: application of diagnostic criteria.
Pasinato F, Souza JA, Corrêa ECR, Silva AMTD
Braz J Otorhinolaryngol 2011 Jul-Aug;77(4):418-425. doi: 10.1590/S1808-86942011000400003. PMID: 21860966Free PMC Article

Recent clinical studies

Etiology

BET 2: Does topical lidocaine improve oral intake in children with painful mouth ulcers?
Daniel RMD, Jason SDO, Jeffrey SJ
Emerg Med J 2020 Feb;37(2):113-114. doi: 10.1136/emermed-2019-209390.3. PMID: 31980553
Temporomandibular disorder and generalized joint hypermobility: application of diagnostic criteria.
Pasinato F, Souza JA, Corrêa ECR, Silva AMTD
Braz J Otorhinolaryngol 2011 Jul-Aug;77(4):418-425. doi: 10.1590/S1808-86942011000400003. PMID: 21860966Free PMC Article
Cyclic and chronic neutropenia.
Dale DC, Welte K
Cancer Treat Res 2011;157:97-108. doi: 10.1007/978-1-4419-7073-2_6. PMID: 21052952
Oral symptoms at menopause--the role of hormone replacement therapy.
Tarkkila L, Linna M, Tiitinen A, Lindqvist C, Meurman JH
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001 Sep;92(3):276-80. doi: 10.1067/moe.2001.117452. PMID: 11552144
Lidocaine overdose: another preventable case?
Gonzalez del Rey J, Wason S, Druckenbrod RW
Pediatr Emerg Care 1994 Dec;10(6):344-6. doi: 10.1097/00006565-199412000-00011. PMID: 7899121

Diagnosis

Recurrent Aphthous Stomatitis.
Sánchez-Bernal J, Conejero C, Conejero R
Actas Dermosifiliogr (Engl Ed) 2020 Jul-Aug;111(6):471-480. Epub 2020 May 22 doi: 10.1016/j.ad.2019.09.004. PMID: 32451064
Oral Histoplasmosis.
Folk GA, Nelson BL
Head Neck Pathol 2017 Dec;11(4):513-516. Epub 2017 Feb 20 doi: 10.1007/s12105-017-0797-y. PMID: 28220360Free PMC Article
Temporomandibular disorder and generalized joint hypermobility: application of diagnostic criteria.
Pasinato F, Souza JA, Corrêa ECR, Silva AMTD
Braz J Otorhinolaryngol 2011 Jul-Aug;77(4):418-425. doi: 10.1590/S1808-86942011000400003. PMID: 21860966Free PMC Article
Cyclic and chronic neutropenia.
Dale DC, Welte K
Cancer Treat Res 2011;157:97-108. doi: 10.1007/978-1-4419-7073-2_6. PMID: 21052952
The painful mouth.
Quail G
Aust Fam Physician 2008 Nov;37(11):935-8. PMID: 19037469

Therapy

BET 2: Does topical lidocaine improve oral intake in children with painful mouth ulcers?
Daniel RMD, Jason SDO, Jeffrey SJ
Emerg Med J 2020 Feb;37(2):113-114. doi: 10.1136/emermed-2019-209390.3. PMID: 31980553
Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis.
Reyes-Gibby CC, Melkonian SC, Wang J, Yu RK, Shelburne SA, Lu C, Gunn GB, Chambers MS, Hanna EY, Yeung SJ, Shete S
PLoS One 2017;12(7):e0180396. Epub 2017 Jul 5 doi: 10.1371/journal.pone.0180396. PMID: 28678827Free PMC Article
Thalidomide's comeback.
Vazquez E
Posit Aware 1998 Jul-Aug;9(4):53-4. PMID: 11365634
Treatment of primary Sjögren's syndrome with hydroxychloroquine: a retrospective, open-label study.
Fox RI, Dixon R, Guarrasi V, Krubel S
Lupus 1996 Jun;5 Suppl 1:S31-6. PMID: 8803908
Lidocaine overdose: another preventable case?
Gonzalez del Rey J, Wason S, Druckenbrod RW
Pediatr Emerg Care 1994 Dec;10(6):344-6. doi: 10.1097/00006565-199412000-00011. PMID: 7899121

Prognosis

Which symptoms negatively affect the oral health-related quality of life in patients with osteonecrosis of the jaw?
Sato T, Kusumoto J, Takeda D, Kishimoto M, Kashin M, Furudoi S, Akashi M
Oral Surg Oral Med Oral Pathol Oral Radiol 2020 Aug;130(2):175-180. Epub 2020 May 31 doi: 10.1016/j.oooo.2020.03.051. PMID: 32493679
Painful mouth ulcers.
Rosa G, Piliang M
Cutis 2018 May;101(5):327;341;342;345. PMID: 29894533
Palliative sedation for cancer patients included in a home care program: a retrospective study.
Calvo-Espinos C, Ruiz de Gaona E, Gonzalez C, Ruiz de Galarreta L, Lopez C
Palliat Support Care 2015 Jun;13(3):619-24. Epub 2014 Apr 24 doi: 10.1017/S1478951514000200. PMID: 24762539
The painful mouth.
Quail G
Aust Fam Physician 2008 Nov;37(11):935-8. PMID: 19037469
Oral symptoms at menopause--the role of hormone replacement therapy.
Tarkkila L, Linna M, Tiitinen A, Lindqvist C, Meurman JH
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001 Sep;92(3):276-80. doi: 10.1067/moe.2001.117452. PMID: 11552144

Clinical prediction guides

Which symptoms negatively affect the oral health-related quality of life in patients with osteonecrosis of the jaw?
Sato T, Kusumoto J, Takeda D, Kishimoto M, Kashin M, Furudoi S, Akashi M
Oral Surg Oral Med Oral Pathol Oral Radiol 2020 Aug;130(2):175-180. Epub 2020 May 31 doi: 10.1016/j.oooo.2020.03.051. PMID: 32493679
Temporomandibular disorder and generalized joint hypermobility: application of diagnostic criteria.
Pasinato F, Souza JA, Corrêa ECR, Silva AMTD
Braz J Otorhinolaryngol 2011 Jul-Aug;77(4):418-425. doi: 10.1590/S1808-86942011000400003. PMID: 21860966Free PMC Article
Administration of morphine sulfate extended-release capsules via gastrostomy: dissolution study and case reports.
Shaiova L, Mori M, Anderson K, Loewen G, Ghalie R, Homel P, Portenoy R
J Palliat Med 2007 Oct;10(5):1063-7. doi: 10.1089/jpm.2006.0262. PMID: 17985962
Oral symptoms at menopause--the role of hormone replacement therapy.
Tarkkila L, Linna M, Tiitinen A, Lindqvist C, Meurman JH
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001 Sep;92(3):276-80. doi: 10.1067/moe.2001.117452. PMID: 11552144
Treatment of primary Sjögren's syndrome with hydroxychloroquine: a retrospective, open-label study.
Fox RI, Dixon R, Guarrasi V, Krubel S
Lupus 1996 Jun;5 Suppl 1:S31-6. PMID: 8803908

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