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Hospital acquired pneumonia

MedGen UID:
679247
•Concept ID:
C0949083
•
Disease or Syndrome
Synonyms: Hospital Acquired Pneumonia; Hospital Acquired Pneumonias; Pneumonia, Hospital Acquired
SNOMED CT: Nosocomial pneumonia (425464007); Hospital acquired pneumonia (425464007); HAP - hospital acquired pneumonia (425464007)

Definition

Pneumonia acquired during a hospital stay. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHospital acquired pneumonia

Professional guidelines

PubMed

Hospital-acquired and ventilator-associated pneumonia: Diagnosis, management, and prevention.
Modi AR, Kovacs CS
Cleve Clin J Med 2020 Oct 1;87(10):633-639. doi: 10.3949/ccjm.87a.19117. PMID: 33004324
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT).
Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, Timsit JF, Welte T, Wunderink R
Eur Respir J 2017 Sep;50(3) Epub 2017 Sep 10 doi: 10.1183/13993003.00582-2017. PMID: 28890434
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society.
Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB, Napolitano LM, O'Grady NP, Bartlett JG, Carratalà J, El Solh AA, Ewig S, Fey PD, File TM Jr, Restrepo MI, Roberts JA, Waterer GW, Cruse P, Knight SL, Brozek JL
Clin Infect Dis 2016 Sep 1;63(5):e61-e111. Epub 2016 Jul 14 doi: 10.1093/cid/ciw353. PMID: 27418577Free PMC Article

Recent clinical studies

Etiology

New Antibiotics for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia.
Bassetti M, Mularoni A, Giacobbe DR, Castaldo N, Vena A
Semin Respir Crit Care Med 2022 Apr;43(2):280-294. Epub 2022 Jan 27 doi: 10.1055/s-0041-1740605. PMID: 35088403
Antibiotics for hospital-acquired pneumonia in neonates and children.
Korang SK, Nava C, Mohana SP, Nygaard U, Jakobsen JC
Cochrane Database Syst Rev 2021 Nov 2;11(11):CD013864. doi: 10.1002/14651858.CD013864.pub2. PMID: 34727368Free PMC Article
Community-acquired Pneumonia and Hospital-acquired Pneumonia.
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
New guidelines for hospital-acquired pneumonia/ventilator-associated pneumonia: USA vs. Europe.
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491
Prevention of hospital-acquired pneumonia.
Lyons PG, Kollef MH
Curr Opin Crit Care 2018 Oct;24(5):370-378. doi: 10.1097/MCC.0000000000000523. PMID: 30015635

Diagnosis

Pneumonia.
Torres A, Cilloniz C, Niederman MS, Menéndez R, Chalmers JD, Wunderink RG, van der Poll T
Nat Rev Dis Primers 2021 Apr 8;7(1):25. doi: 10.1038/s41572-021-00259-0. PMID: 33833230
Hospital-acquired and ventilator-associated pneumonia: Diagnosis, management, and prevention.
Modi AR, Kovacs CS
Cleve Clin J Med 2020 Oct 1;87(10):633-639. doi: 10.3949/ccjm.87a.19117. PMID: 33004324
Community-acquired Pneumonia and Hospital-acquired Pneumonia.
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT).
Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, Timsit JF, Welte T, Wunderink R
Eur Respir J 2017 Sep;50(3) Epub 2017 Sep 10 doi: 10.1183/13993003.00582-2017. PMID: 28890434
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society.
Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB, Napolitano LM, O'Grady NP, Bartlett JG, Carratalà J, El Solh AA, Ewig S, Fey PD, File TM Jr, Restrepo MI, Roberts JA, Waterer GW, Cruse P, Knight SL, Brozek JL
Clin Infect Dis 2016 Sep 1;63(5):e61-e111. Epub 2016 Jul 14 doi: 10.1093/cid/ciw353. PMID: 27418577Free PMC Article

Therapy

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update.
Klompas M, Branson R, Cawcutt K, Crist M, Eichenwald EC, Greene LR, Lee G, Maragakis LL, Powell K, Priebe GP, Speck K, Yokoe DS, Berenholtz SM
Infect Control Hosp Epidemiol 2022 Jun;43(6):687-713. Epub 2022 May 20 doi: 10.1017/ice.2022.88. PMID: 35589091
New Antibiotics for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia.
Bassetti M, Mularoni A, Giacobbe DR, Castaldo N, Vena A
Semin Respir Crit Care Med 2022 Apr;43(2):280-294. Epub 2022 Jan 27 doi: 10.1055/s-0041-1740605. PMID: 35088403
Community-acquired Pneumonia and Hospital-acquired Pneumonia.
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
Prevention of hospital-acquired pneumonia.
Lyons PG, Kollef MH
Curr Opin Crit Care 2018 Oct;24(5):370-378. doi: 10.1097/MCC.0000000000000523. PMID: 30015635
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT).
Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, Timsit JF, Welte T, Wunderink R
Eur Respir J 2017 Sep;50(3) Epub 2017 Sep 10 doi: 10.1183/13993003.00582-2017. PMID: 28890434

Prognosis

Current treatment of nosocomial pneumonia and ventilator-associated pneumonia.
Plata-Menchaca EP, Ferrer R
Rev Esp Quimioter 2022 Oct;35 Suppl 3(Suppl 3):25-29. Epub 2022 Oct 24 doi: 10.37201/req/s03.06.2022. PMID: 36285853Free PMC Article
HAP and VAP after Guidelines.
Wicky PH, Martin-Loeches I, Timsit JF
Semin Respir Crit Care Med 2022 Apr;43(2):248-254. Epub 2022 Jan 18 doi: 10.1055/s-0041-1740246. PMID: 35042265
Management of Ventilator-Associated Pneumonia: Guidelines.
Metersky ML, Kalil AC
Clin Chest Med 2018 Dec;39(4):797-808. doi: 10.1016/j.ccm.2018.08.002. PMID: 30390750
New guidelines for hospital-acquired pneumonia/ventilator-associated pneumonia: USA vs. Europe.
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491
Legionnaires' disease.
Cunha BA, Burillo A, Bouza E
Lancet 2016 Jan 23;387(10016):376-385. Epub 2015 Jul 28 doi: 10.1016/S0140-6736(15)60078-2. PMID: 26231463

Clinical prediction guides

New guidelines for hospital-acquired pneumonia/ventilator-associated pneumonia: USA vs. Europe.
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491
Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial.
Boden I, Skinner EH, Browning L, Reeve J, Anderson L, Hill C, Robertson IK, Story D, Denehy L
BMJ 2018 Jan 24;360:j5916. doi: 10.1136/bmj.j5916. PMID: 29367198Free PMC Article
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults.
Pugh R, Grant C, Cooke RP, Dempsey G
Cochrane Database Syst Rev 2015 Aug 24;2015(8):CD007577. doi: 10.1002/14651858.CD007577.pub3. PMID: 26301604Free PMC Article
Pneumonia due to Pseudomonas aeruginosa: part I: epidemiology, clinical diagnosis, and source.
Fujitani S, Sun HY, Yu VL, Weingarten JA
Chest 2011 Apr;139(4):909-919. doi: 10.1378/chest.10-0166. PMID: 21467058
Nurse staffing and quality of patient care.
Kane RL, Shamliyan T, Mueller C, Duval S, Wilt TJ
Evid Rep Technol Assess (Full Rep) 2007 Mar;(151):1-115. PMID: 17764206Free PMC Article

Recent systematic reviews

Antibiotics for hospital-acquired pneumonia in neonates and children.
Korang SK, Nava C, Mohana SP, Nygaard U, Jakobsen JC
Cochrane Database Syst Rev 2021 Nov 2;11(11):CD013864. doi: 10.1002/14651858.CD013864.pub2. PMID: 34727368Free PMC Article
Strategies to reduce non-ventilator-associated hospital-acquired pneumonia: A systematic review.
Mitchell BG, Russo PL, Cheng AC, Stewardson AJ, Rosebrock H, Curtis SJ, Robinson S, Kiernan M
Infect Dis Health 2019 Nov;24(4):229-239. Epub 2019 Jul 4 doi: 10.1016/j.idh.2019.06.002. PMID: 31279704
The preventable proportion of healthcare-associated infections 2005-2016: Systematic review and meta-analysis.
Schreiber PW, Sax H, Wolfensberger A, Clack L, Kuster SP; Swissnoso
Infect Control Hosp Epidemiol 2018 Nov;39(11):1277-1295. Epub 2018 Sep 20 doi: 10.1017/ice.2018.183. PMID: 30234463
Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.
Chu DK, Kim LH, Young PJ, Zamiri N, Almenawer SA, Jaeschke R, Szczeklik W, Schünemann HJ, Neary JD, Alhazzani W
Lancet 2018 Apr 28;391(10131):1693-1705. Epub 2018 Apr 26 doi: 10.1016/S0140-6736(18)30479-3. PMID: 29726345
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults.
Pugh R, Grant C, Cooke RP, Dempsey G
Cochrane Database Syst Rev 2015 Aug 24;2015(8):CD007577. doi: 10.1002/14651858.CD007577.pub3. PMID: 26301604Free PMC Article

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