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Hemorrhagic disease

MedGen UID:
6799
Concept ID:
C0019087
Disease or Syndrome
Synonyms: Diatheses, Hemorrhagic; Diathesis, Hemorrhagic; Disorder, Hemorrhagic; Disorders, Hemorrhagic; Hemorrhagic Diatheses; Hemorrhagic Diathesis; Hemorrhagic Disorder; Hemorrhagic Disorders
 
Monarch Initiative: MONDO:0002243

Definition

Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels (hemostatic disorders). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHemorrhagic disease

Professional guidelines

PubMed

Wright WF, Pritt BS
Diagn Microbiol Infect Dis 2012 Jul;73(3):215-20. Epub 2012 Apr 26 doi: 10.1016/j.diagmicrobio.2012.03.021. PMID: 22541792
Thomas SV
J Postgrad Med 2006 Jan-Mar;52(1):57-64. PMID: 16534170
Valaes TN, Harvey-Wilkes K
Clin Perinatol 1990 Jun;17(2):245-73. PMID: 2196130

Recent clinical studies

Etiology

Söbü E, Özdemir N, Uysal S, Buyru N, Celkan T
J Pediatr Hematol Oncol 2019 Oct;41(7):519-524. doi: 10.1097/MPH.0000000000001539. PMID: 31259821
Hubálek Z, Rudolf I
Parasitol Res 2012 Jul;111(1):9-36. Epub 2012 Apr 18 doi: 10.1007/s00436-012-2910-1. PMID: 22526290
Barrette RW, Xu L, Rowland JM, McIntosh MT
Infect Genet Evol 2011 Oct;11(7):1514-9. Epub 2011 Jun 30 doi: 10.1016/j.meegid.2011.06.017. PMID: 21742058Free PMC Article
Gardner CL, Ryman KD
Clin Lab Med 2010 Mar;30(1):237-60. doi: 10.1016/j.cll.2010.01.001. PMID: 20513550Free PMC Article
Huysman MW, Sauer PJ
Curr Opin Pediatr 1994 Apr;6(2):129-34. doi: 10.1097/00008480-199404000-00002. PMID: 8032391

Diagnosis

Gardner CL, Ryman KD
Clin Lab Med 2010 Mar;30(1):237-60. doi: 10.1016/j.cll.2010.01.001. PMID: 20513550Free PMC Article
Hossler EW
Dermatol Ther 2009 Jul-Aug;22(4):353-66. doi: 10.1111/j.1529-8019.2009.01247.x. PMID: 19580579
Nurden AT
Orphanet J Rare Dis 2006 Apr 6;1:10. doi: 10.1186/1750-1172-1-10. PMID: 16722529Free PMC Article
Lashkevich VA, Koroleva GA, Lukashev AN, Denisova EV, Katargina LA
Rev Med Virol 2004 Jul-Aug;14(4):241-54. doi: 10.1002/rmv.433. PMID: 15248252
Huysman MW, Sauer PJ
Curr Opin Pediatr 1994 Apr;6(2):129-34. doi: 10.1097/00008480-199404000-00002. PMID: 8032391

Therapy

Zhou M, Hu Z, Zhang C, Wu L, Li Z, Liang D
Curr Gene Ther 2020;20(2):142-151. doi: 10.2174/1566523220666200806110849. PMID: 32767930
Furuyama W, Marzi A
Annu Rev Virol 2019 Sep 29;6(1):435-458. doi: 10.1146/annurev-virology-092818-015708. PMID: 31567063
Marcinkiewicz J, Bryniarski K, Nazimek K
Folia Med Cracov 2014;54(3):39-48. PMID: 25694094
Hossler EW
Dermatol Ther 2009 Jul-Aug;22(4):353-66. doi: 10.1111/j.1529-8019.2009.01247.x. PMID: 19580579
Nurden AT
Orphanet J Rare Dis 2006 Apr 6;1:10. doi: 10.1186/1750-1172-1-10. PMID: 16722529Free PMC Article

Prognosis

Bezerra EH, Melo-Hanchuk TD, Marques RE
Exp Biol Med (Maywood) 2023 Oct;248(19):1624-1634. Epub 2023 Nov 8 doi: 10.1177/15353702231199071. PMID: 37937408Free PMC Article
Broeckel RM, Feldmann F, McNally KL, Chiramel AI, Sturdevant GL, Leung JM, Hanley PW, Lovaglio J, Rosenke R, Scott DP, Saturday G, Bouamr F, Rasmussen AL, Robertson SJ, Best SM
PLoS Pathog 2021 Dec;17(12):e1009678. Epub 2021 Dec 2 doi: 10.1371/journal.ppat.1009678. PMID: 34855915Free PMC Article
Liu C, Zhang K, Shen H, Yao X, Sun Q, Chen G
Int J Mol Med 2018 Feb;41(2):624-630. Epub 2017 Nov 22 doi: 10.3892/ijmm.2017.3279. PMID: 29207014
Barrette RW, Xu L, Rowland JM, McIntosh MT
Infect Genet Evol 2011 Oct;11(7):1514-9. Epub 2011 Jun 30 doi: 10.1016/j.meegid.2011.06.017. PMID: 21742058Free PMC Article
Nurden AT
Orphanet J Rare Dis 2006 Apr 6;1:10. doi: 10.1186/1750-1172-1-10. PMID: 16722529Free PMC Article

Clinical prediction guides

Bezerra EH, Melo-Hanchuk TD, Marques RE
Exp Biol Med (Maywood) 2023 Oct;248(19):1624-1634. Epub 2023 Nov 8 doi: 10.1177/15353702231199071. PMID: 37937408Free PMC Article
Greywal T, Kusari A, Han AM, Borok J, Proudfoot JA, Ahluwalia J, Friedlander SF
Pediatr Dermatol 2022 Jul;39(4):535-540. Epub 2022 May 18 doi: 10.1111/pde.14990. PMID: 35584791
Broeckel RM, Feldmann F, McNally KL, Chiramel AI, Sturdevant GL, Leung JM, Hanley PW, Lovaglio J, Rosenke R, Scott DP, Saturday G, Bouamr F, Rasmussen AL, Robertson SJ, Best SM
PLoS Pathog 2021 Dec;17(12):e1009678. Epub 2021 Dec 2 doi: 10.1371/journal.ppat.1009678. PMID: 34855915Free PMC Article
Barrette RW, Xu L, Rowland JM, McIntosh MT
Infect Genet Evol 2011 Oct;11(7):1514-9. Epub 2011 Jun 30 doi: 10.1016/j.meegid.2011.06.017. PMID: 21742058Free PMC Article
Lashkevich VA, Koroleva GA, Lukashev AN, Denisova EV, Katargina LA
Rev Med Virol 2004 Jul-Aug;14(4):241-54. doi: 10.1002/rmv.433. PMID: 15248252

Recent systematic reviews

Puckett RM, Offringa M
Cochrane Database Syst Rev 2000;2000(4):CD002776. doi: 10.1002/14651858.CD002776. PMID: 11034761Free PMC Article

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