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Mucosal ulcer

MedGen UID:
68630
•Concept ID:
C0236053
•
Disease or Syndrome
Synonyms: Mucosal ulceration; Mucosal ulcerations; Mucosal ulcers; Mucous membrane ulceration
SNOMED CT: Mucosal ulcer (95356008); Mucosal ulceration (95356008)

Definition

A circumscribed loss of integrity of the mucous membrane. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMucosal ulcer

Professional guidelines

PubMed

Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease.
Edmans JG, Ollington B, Colley HE, Santocildes-Romero ME, Siim Madsen L, Hatton PV, Spain SG, Murdoch C
J Control Release 2022 Oct;350:146-157. Epub 2022 Aug 18 doi: 10.1016/j.jconrel.2022.08.016. PMID: 35973471
Banhasasim-Tang Treatment Reduces the Severity of Esophageal Mucosal Ulcer on Chronic Acid Reflux Esophagitis in Rats.
Shin MR, Seo BI, Son CG, Roh SS, An HJ
Biomed Res Int 2017;2017:7157212. Epub 2017 Mar 2 doi: 10.1155/2017/7157212. PMID: 28349065Free PMC Article
The role of brachytherapy in the management of oropharyngeal carcinomas: the Trento experience.
Bolner A, Mussari S, Fellin G, Pani G, Busana L, Caffo O, Tomio L
Tumori 2002 Mar-Apr;88(2):137-41. doi: 10.1177/030089160208800211. PMID: 12088254

Recent clinical studies

Etiology

Post radiation mucosal ulcer risk after a hypofractionated stereotactic boost and conventional fractionated radiotherapy for oropharyngeal carcinoma.
Verduijn GM, Petit SF, Lauwers I, van Norden Y, Sijtsema ND, Sewnaik A, Mast H, Capala M, Nout R, Baker S, van Meerten E, Hoogeman MS, van der Lugt A, Heemsbergen WD
Acta Oncol 2023 Jan;62(1):40-47. Epub 2022 Dec 28 doi: 10.1080/0284186X.2022.2159772. PMID: 36576773
A retrospective analysis of transanal surgical management of 291 cases with rectal foreign bodies.
Zhang Y, Han Y, Xu H, Chen D, Gao H, Yuan H, Zeng X
Int J Colorectal Dis 2022 Oct;37(10):2167-2172. Epub 2022 Sep 3 doi: 10.1007/s00384-022-04230-7. PMID: 36057731
Associations of lymphocyte subpopulations with clinical phenotypes and long-term outcomes in juvenile-onset systemic lupus erythematosus.
Lerkvaleekul B, Apiwattanakul N, Tangnararatchakit K, Jirapattananon N, Srisala S, Vilaiyuk S
PLoS One 2022;17(2):e0263536. Epub 2022 Feb 7 doi: 10.1371/journal.pone.0263536. PMID: 35130317Free PMC Article
Small molecule FAK activator promotes human intestinal epithelial monolayer wound closure and mouse ulcer healing.
Wang Q, More SK, Vomhof-DeKrey EE, Golovko MY, Basson MD
Sci Rep 2019 Oct 11;9(1):14669. doi: 10.1038/s41598-019-51183-z. PMID: 31604999Free PMC Article
Pancreatic heterotopia: a reappraisal and clinicopathologic analysis of 32 cases.
Pang LC
South Med J 1988 Oct;81(10):1264-75. PMID: 3051429

Diagnosis

Stomach ulcer caused by mistakenly oral medication of 14,400 mg ibuprofen: A case report.
Meijuan Z, Yu P, Yuan J, Yu T, Sun D
Medicine (Baltimore) 2023 May 19;102(20):e33812. doi: 10.1097/MD.0000000000033812. PMID: 37335722Free PMC Article
A retrospective analysis of transanal surgical management of 291 cases with rectal foreign bodies.
Zhang Y, Han Y, Xu H, Chen D, Gao H, Yuan H, Zeng X
Int J Colorectal Dis 2022 Oct;37(10):2167-2172. Epub 2022 Sep 3 doi: 10.1007/s00384-022-04230-7. PMID: 36057731
Common benign and malignant oral mucosal disease.
Wong T, Yap T, Wiesenfeld D
Aust J Gen Pract 2020 Sep;49(9):568-573. doi: 10.31128/AJGP-02-20-5250-01. PMID: 32864671
Oral tuberculosis mimicking a traumatic denture ulcer.
Lee ST, Jang SB, Kwon TG, Choi SY
J Prosthet Dent 2019 Feb;121(2):225-228. Epub 2018 Oct 26 doi: 10.1016/j.prosdent.2018.04.024. PMID: 30722984
Pancreatic heterotopia: a reappraisal and clinicopathologic analysis of 32 cases.
Pang LC
South Med J 1988 Oct;81(10):1264-75. PMID: 3051429

Therapy

Stomach ulcer caused by mistakenly oral medication of 14,400 mg ibuprofen: A case report.
Meijuan Z, Yu P, Yuan J, Yu T, Sun D
Medicine (Baltimore) 2023 May 19;102(20):e33812. doi: 10.1097/MD.0000000000033812. PMID: 37335722Free PMC Article
Post radiation mucosal ulcer risk after a hypofractionated stereotactic boost and conventional fractionated radiotherapy for oropharyngeal carcinoma.
Verduijn GM, Petit SF, Lauwers I, van Norden Y, Sijtsema ND, Sewnaik A, Mast H, Capala M, Nout R, Baker S, van Meerten E, Hoogeman MS, van der Lugt A, Heemsbergen WD
Acta Oncol 2023 Jan;62(1):40-47. Epub 2022 Dec 28 doi: 10.1080/0284186X.2022.2159772. PMID: 36576773
Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease.
Edmans JG, Ollington B, Colley HE, Santocildes-Romero ME, Siim Madsen L, Hatton PV, Spain SG, Murdoch C
J Control Release 2022 Oct;350:146-157. Epub 2022 Aug 18 doi: 10.1016/j.jconrel.2022.08.016. PMID: 35973471
Long-term outcomes of skull base chordoma treated with high-dose carbon-ion radiotherapy.
Koto M, Ikawa H, Kaneko T, Hagiwara Y, Hayashi K, Tsuji H
Head Neck 2020 Sep;42(9):2607-2613. Epub 2020 May 30 doi: 10.1002/hed.26307. PMID: 32472716Free PMC Article
Buccal mucosal ulcer healing effect of rhEGF/Eudispert hv hydrogel.
Park JS, Yoon JI, Li H, Moon DC, Han K
Arch Pharm Res 2003 Aug;26(8):659-65. doi: 10.1007/BF02976717. PMID: 12967203

Prognosis

Analysis of risk factors and development of a nomogram prediction model for lupus nephritis in systemic lupus erythematosus patients.
Tang Z, Wang JM, Qin JM, Wen LM
Lupus 2023 Aug;32(9):1084-1092. Epub 2023 Jul 22 doi: 10.1177/09612033231189904. PMID: 37480363
An update on oral clinical courses among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A clinical follow-up (a prospective prevalent cohort) study.
Gebretsadik HG
PLoS One 2022;17(10):e0275817. Epub 2022 Oct 21 doi: 10.1371/journal.pone.0275817. PMID: 36269692Free PMC Article
Associations of lymphocyte subpopulations with clinical phenotypes and long-term outcomes in juvenile-onset systemic lupus erythematosus.
Lerkvaleekul B, Apiwattanakul N, Tangnararatchakit K, Jirapattananon N, Srisala S, Vilaiyuk S
PLoS One 2022;17(2):e0263536. Epub 2022 Feb 7 doi: 10.1371/journal.pone.0263536. PMID: 35130317Free PMC Article
Duodenal ulcer promoting gene (DupA), plasticity region genes and sigma factors in H. pyloristrains from Nigeria.
Jolaiya TF, Fowora MA, Onyekwere C, Ugiagbe R, Agbo II, Lesi O, Ndububa DA, Adekanle O, Njom HA, Idowu A, Adeleye IA, Bamidele M, Ngoka FN, Palamides PF, Smith SI
J Infect Dev Ctries 2020 Feb 29;14(2):162-168. doi: 10.3855/jidc.11746. PMID: 32146450
Multicenter Study of Carbon-Ion Radiation Therapy for Mucosal Melanoma of the Head and Neck: Subanalysis of the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS) Study (1402 HN).
Koto M, Demizu Y, Saitoh JI, Suefuji H, Tsuji H, Okimoto T, Ohno T, Shioyama Y, Takagi R, Nemoto K, Nakano T, Kamada T; Japan Carbon-Ion Radiation Oncology Study Group
Int J Radiat Oncol Biol Phys 2017 Apr 1;97(5):1054-1060. Epub 2016 Dec 26 doi: 10.1016/j.ijrobp.2016.12.028. PMID: 28332989

Clinical prediction guides

Analysis of risk factors and development of a nomogram prediction model for lupus nephritis in systemic lupus erythematosus patients.
Tang Z, Wang JM, Qin JM, Wen LM
Lupus 2023 Aug;32(9):1084-1092. Epub 2023 Jul 22 doi: 10.1177/09612033231189904. PMID: 37480363
Post radiation mucosal ulcer risk after a hypofractionated stereotactic boost and conventional fractionated radiotherapy for oropharyngeal carcinoma.
Verduijn GM, Petit SF, Lauwers I, van Norden Y, Sijtsema ND, Sewnaik A, Mast H, Capala M, Nout R, Baker S, van Meerten E, Hoogeman MS, van der Lugt A, Heemsbergen WD
Acta Oncol 2023 Jan;62(1):40-47. Epub 2022 Dec 28 doi: 10.1080/0284186X.2022.2159772. PMID: 36576773
Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease.
Edmans JG, Ollington B, Colley HE, Santocildes-Romero ME, Siim Madsen L, Hatton PV, Spain SG, Murdoch C
J Control Release 2022 Oct;350:146-157. Epub 2022 Aug 18 doi: 10.1016/j.jconrel.2022.08.016. PMID: 35973471
Associations of lymphocyte subpopulations with clinical phenotypes and long-term outcomes in juvenile-onset systemic lupus erythematosus.
Lerkvaleekul B, Apiwattanakul N, Tangnararatchakit K, Jirapattananon N, Srisala S, Vilaiyuk S
PLoS One 2022;17(2):e0263536. Epub 2022 Feb 7 doi: 10.1371/journal.pone.0263536. PMID: 35130317Free PMC Article
Duodenal ulcer promoting gene (DupA), plasticity region genes and sigma factors in H. pyloristrains from Nigeria.
Jolaiya TF, Fowora MA, Onyekwere C, Ugiagbe R, Agbo II, Lesi O, Ndububa DA, Adekanle O, Njom HA, Idowu A, Adeleye IA, Bamidele M, Ngoka FN, Palamides PF, Smith SI
J Infect Dev Ctries 2020 Feb 29;14(2):162-168. doi: 10.3855/jidc.11746. PMID: 32146450

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