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Attention Deficit and Disruptive Behavior Disorders

MedGen UID:
68635
•Concept ID:
C0236964
•
Pathologic Function
Synonym: Attention Deficit and Disruptive Behavioral Disorders

Definition

Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors. [from MeSH]

Professional guidelines

PubMed

The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder.
Faraone SV, Banaschewski T, Coghill D, Zheng Y, Biederman J, Bellgrove MA, Newcorn JH, Gignac M, Al Saud NM, Manor I, Rohde LA, Yang L, Cortese S, Almagor D, Stein MA, Albatti TH, Aljoudi HF, Alqahtani MMJ, Asherson P, Atwoli L, Bölte S, Buitelaar JK, Crunelle CL, Daley D, Dalsgaard S, Döpfner M, Espinet S, Fitzgerald M, Franke B, Gerlach M, Haavik J, Hartman CA, Hartung CM, Hinshaw SP, Hoekstra PJ, Hollis C, Kollins SH, Sandra Kooij JJ, Kuntsi J, Larsson H, Li T, Liu J, Merzon E, Mattingly G, Mattos P, McCarthy S, Mikami AY, Molina BSG, Nigg JT, Purper-Ouakil D, Omigbodun OO, Polanczyk GV, Pollak Y, Poulton AS, Rajkumar RP, Reding A, Reif A, Rubia K, Rucklidge J, Romanos M, Ramos-Quiroga JA, Schellekens A, Scheres A, Schoeman R, Schweitzer JB, Shah H, Solanto MV, Sonuga-Barke E, Soutullo C, Steinhausen HC, Swanson JM, Thapar A, Tripp G, van de Glind G, van den Brink W, Van der Oord S, Venter A, Vitiello B, Walitza S, Wang Y
Neurosci Biobehav Rev 2021 Sep;128:789-818. Epub 2021 Feb 4 doi: 10.1016/j.neubiorev.2021.01.022. PMID: 33549739Free PMC Article
Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.
Wolraich ML, Hagan JF Jr, Allan C, Chan E, Davison D, Earls M, Evans SW, Flinn SK, Froehlich T, Frost J, Holbrook JR, Lehmann CU, Lessin HR, Okechukwu K, Pierce KL, Winner JD, Zurhellen W; SUBCOMMITTEE ON CHILDREN AND ADOLESCENTS WITH ATTENTION-DEFICIT/HYPERACTIVE DISORDER
Pediatrics 2019 Oct;144(4) doi: 10.1542/peds.2019-2528. PMID: 31570648Free PMC Article
ADHD and behavioral disorders: Assessment, management, and an update from DSM-5.
Austerman J
Cleve Clin J Med 2015 Nov;82(11 Suppl 1):S2-7. doi: 10.3949/ccjm.82.s1.01. PMID: 26555810

Recent clinical studies

Etiology

Oppositional defiant disorder.
Hawes DJ, Gardner F, Dadds MR, Frick PJ, Kimonis ER, Burke JD, Fairchild G
Nat Rev Dis Primers 2023 Jun 22;9(1):31. doi: 10.1038/s41572-023-00441-6. PMID: 37349322
Disruptive Behavior Disorders: The Challenge of Delineating Mechanisms in the Face of Heterogeneity.
Viding E, McCrory E
Am J Psychiatry 2020 Sep 1;177(9):811-817. doi: 10.1176/appi.ajp.2020.20070998. PMID: 32867523
Disruptive Behavior Disorders in Children 0 to 6 Years Old.
Tandon M, Giedinghagen A
Child Adolesc Psychiatr Clin N Am 2017 Jul;26(3):491-502. Epub 2017 Mar 15 doi: 10.1016/j.chc.2017.02.005. PMID: 28577605
Development and etiology of disruptive and delinquent behavior.
Loeber R, Burke JD, Pardini DA
Annu Rev Clin Psychol 2009;5:291-310. doi: 10.1146/annurev.clinpsy.032408.153631. PMID: 19154139
Oppositional defiant disorder.
Hamilton SS, Armando J
Am Fam Physician 2008 Oct 1;78(7):861-6. PMID: 18841736

Diagnosis

Oppositional defiant disorder.
Hawes DJ, Gardner F, Dadds MR, Frick PJ, Kimonis ER, Burke JD, Fairchild G
Nat Rev Dis Primers 2023 Jun 22;9(1):31. doi: 10.1038/s41572-023-00441-6. PMID: 37349322
Disruptive Behavior Disorders: The Challenge of Delineating Mechanisms in the Face of Heterogeneity.
Viding E, McCrory E
Am J Psychiatry 2020 Sep 1;177(9):811-817. doi: 10.1176/appi.ajp.2020.20070998. PMID: 32867523
Disruptive Behavior Disorders in Children 0 to 6 Years Old.
Tandon M, Giedinghagen A
Child Adolesc Psychiatr Clin N Am 2017 Jul;26(3):491-502. Epub 2017 Mar 15 doi: 10.1016/j.chc.2017.02.005. PMID: 28577605
Oppositional defiant disorder.
Hamilton SS, Armando J
Am Fam Physician 2008 Oct 1;78(7):861-6. PMID: 18841736
Neuropsychiatric disorders.
Gillberg C
Curr Opin Neurol 1998 Apr;11(2):109-14. doi: 10.1097/00019052-199804000-00005. PMID: 9551289

Therapy

Complementary and Integrative Treatments of Aggressiveness/Emotion Dysregulation: Associated with Disruptive Disorders and Disruptive Mood Dysregulation Disorder.
Bhatara VS, Bernstein B, Fazili S
Child Adolesc Psychiatr Clin N Am 2023 Apr;32(2):297-315. doi: 10.1016/j.chc.2022.08.010. PMID: 37147041
Pharmacotherapy of Disruptive Behaviors in Children with Intellectual Disabilities.
Hodgins GE, Winsor K, Barnhill J
Paediatr Drugs 2022 Sep;24(5):465-482. Epub 2022 Jul 4 doi: 10.1007/s40272-022-00517-y. PMID: 35781194
Using antipsychotics for behavioral problems in children.
Shafiq S, Pringsheim T
Expert Opin Pharmacother 2018 Sep;19(13):1475-1488. Epub 2018 Aug 13 doi: 10.1080/14656566.2018.1509069. PMID: 30102079
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
Loy JH, Merry SN, Hetrick SE, Stasiak K
Cochrane Database Syst Rev 2017 Aug 9;8(8):CD008559. doi: 10.1002/14651858.CD008559.pub3. PMID: 28791693Free PMC Article
The Diagnosis and Treatment of Behavioral Disorders in Dementia.
Kratz T
Dtsch Arztebl Int 2017 Jun 30;114(26):447-454. doi: 10.3238/arztebl.2017.0447. PMID: 28705297Free PMC Article

Prognosis

Incidence and comorbidities of disruptive behavior disorders diagnosed in Finnish specialist psychiatric services.
Uotila J, Gyllenberg D, Korhonen L, Hinkka-Yli-Salomäki S, Heinonen E, Chudal R, Gissler M, Sourander A
Soc Psychiatry Psychiatr Epidemiol 2021 Nov;56(11):2063-2072. Epub 2021 Jan 4 doi: 10.1007/s00127-020-02015-3. PMID: 33398496
A Systematic Review and Meta-Analysis of the Risk of Disruptive Behavioral Disorders in the Offspring of Parents with Severe Psychiatric Disorders.
Ayano G, Betts K, Maravilla JC, Alati R
Child Psychiatry Hum Dev 2021 Feb;52(1):77-95. doi: 10.1007/s10578-020-00989-4. PMID: 32291561
Viewing preschool disruptive behavior disorders and attention-deficit/hyperactivity disorder through a developmental lens: what we know and what we need to know.
Chacko A, Wakschlag L, Hill C, Danis B, Espy KA
Child Adolesc Psychiatr Clin N Am 2009 Jul;18(3):627-43. doi: 10.1016/j.chc.2009.02.003. PMID: 19486842Free PMC Article
Development and etiology of disruptive and delinquent behavior.
Loeber R, Burke JD, Pardini DA
Annu Rev Clin Psychol 2009;5:291-310. doi: 10.1146/annurev.clinpsy.032408.153631. PMID: 19154139
Attention-deficit/hyperactivity disorder and its comorbidities in women and girls: an evolving picture.
Quinn PO
Curr Psychiatry Rep 2008 Oct;10(5):419-23. doi: 10.1007/s11920-008-0067-5. PMID: 18803916

Clinical prediction guides

Psychiatric comorbidities of children with elimination disorders.
Gizli Çoban Ö, Önder A, Sürer Adanır A
Arch Pediatr 2021 Jan;28(1):59-63. Epub 2020 Nov 19 doi: 10.1016/j.arcped.2020.10.002. PMID: 33223199
Closing the gap: unmet needs of individuals with impulsive aggressive behavior observed in children and adolescents.
Robb AS, Connor DF, Amann BH, Vitiello B, Nasser A, O'Neal W, Schwabe S, Ceresoli-Borroni G, Newcorn JH, Candler SA, Buitelaar JK, Findling RL
CNS Spectr 2021 Oct;26(5):448-456. Epub 2020 Mar 31 doi: 10.1017/S1092852920001224. PMID: 32228725
Clinical utility of the CBCL Dysregulation Profile in children with disruptive behavior.
Aitken M, Battaglia M, Marino C, Mahendran N, Andrade BF
J Affect Disord 2019 Jun 15;253:87-95. Epub 2019 Apr 9 doi: 10.1016/j.jad.2019.04.034. PMID: 31029857
Disentangling Heterogeneity of Childhood Disruptive Behavior Problems Into Dimensions and Subgroups.
Bolhuis K, Lubke GH, van der Ende J, Bartels M, van Beijsterveldt CEM, Lichtenstein P, Larsson H, Jaddoe VWV, Kushner SA, Verhulst FC, Boomsma DI, Tiemeier H
J Am Acad Child Adolesc Psychiatry 2017 Aug;56(8):678-686. Epub 2017 Jun 29 doi: 10.1016/j.jaac.2017.05.019. PMID: 28735697
Development and etiology of disruptive and delinquent behavior.
Loeber R, Burke JD, Pardini DA
Annu Rev Clin Psychol 2009;5:291-310. doi: 10.1146/annurev.clinpsy.032408.153631. PMID: 19154139

Recent systematic reviews

Executive (dys)functions and ODD and CD: A systematic review and meta-analysis.
Figueiredo P, Ramião E, Barroso R, Barbosa F
Neuropsychology 2023 Feb;37(2):133-156. Epub 2022 Nov 28 doi: 10.1037/neu0000881. PMID: 36442005
Systematic Review and Meta-analysis: Pharmacological and Nonpharmacological Interventions for Persistent Nonepisodic Irritability.
Breaux R, Baweja R, Eadeh HM, Shroff DM, Cash AR, Swanson CS, Knehans A, Waxmonsky JG
J Am Acad Child Adolesc Psychiatry 2023 Mar;62(3):318-334. Epub 2022 Jun 14 doi: 10.1016/j.jaac.2022.05.012. PMID: 35714838
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
Loy JH, Merry SN, Hetrick SE, Stasiak K
Cochrane Database Syst Rev 2017 Aug 9;8(8):CD008559. doi: 10.1002/14651858.CD008559.pub3. PMID: 28791693Free PMC Article
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article
Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents.
Ipser J, Stein DJ
Psychopharmacology (Berl) 2007 Mar;191(1):127-40. Epub 2006 Sep 16 doi: 10.1007/s00213-006-0537-6. PMID: 16983542

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