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Ovarian mass

MedGen UID:
68708
•Concept ID:
C0240611
•
Finding
Synonyms: Mass of ovary; Mass of Ovary; Ovarian Mass
SNOMED CT: Mass of ovary (289922002); Ovarian mass (289922002)
 
HPO: HP:0034879

Definition

A swelling or enlargment localized to the ovary. The word mass is usually used at an early stage of the diagnostic workup before the precise nature of the swelling has been determined. [from HPO]

Professional guidelines

PubMed

Adnexal Mass Imaging: Contemporary Guidelines for Clinical Practice.
Roseland ME, Maturen KE, Shampain KL, Wasnik AP, Stein EB
Radiol Clin North Am 2023 Jul;61(4):671-685. doi: 10.1016/j.rcl.2023.02.002. PMID: 37169431
Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.
Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423
Spectrum of Ovarian Incidentalomas: Diagnosis and Management.
Mansour S, Hamed S, Kamal R
Br J Radiol 2023 Feb;96(1142):20211325. Epub 2022 Feb 18 doi: 10.1259/bjr.20211325. PMID: 35142537Free PMC Article

Recent clinical studies

Etiology

Adnexal Mass Imaging: Contemporary Guidelines for Clinical Practice.
Roseland ME, Maturen KE, Shampain KL, Wasnik AP, Stein EB
Radiol Clin North Am 2023 Jul;61(4):671-685. doi: 10.1016/j.rcl.2023.02.002. PMID: 37169431
Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.
Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423
High risk and low prevalence diseases: Ovarian torsion.
Bridwell RE, Koyfman A, Long B
Am J Emerg Med 2022 Jun;56:145-150. Epub 2022 Mar 31 doi: 10.1016/j.ajem.2022.03.046. PMID: 35397355
Ovarian Torsion in Adolescents with and without ovarian mass: A Cross-sectional Study.
Karaca SY, İleri A
J Pediatr Adolesc Gynecol 2021 Dec;34(6):857-861. Epub 2021 May 25 doi: 10.1016/j.jpag.2021.05.007. PMID: 34044177
Blood biomarkers for the non-invasive diagnosis of endometriosis.
Nisenblat V, Bossuyt PM, Shaikh R, Farquhar C, Jordan V, Scheffers CS, Mol BW, Johnson N, Hull ML
Cochrane Database Syst Rev 2016 May 1;2016(5):CD012179. doi: 10.1002/14651858.CD012179. PMID: 27132058Free PMC Article

Diagnosis

Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.
Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423
Spectrum of Ovarian Incidentalomas: Diagnosis and Management.
Mansour S, Hamed S, Kamal R
Br J Radiol 2023 Feb;96(1142):20211325. Epub 2022 Feb 18 doi: 10.1259/bjr.20211325. PMID: 35142537Free PMC Article
High risk and low prevalence diseases: Ovarian torsion.
Bridwell RE, Koyfman A, Long B
Am J Emerg Med 2022 Jun;56:145-150. Epub 2022 Mar 31 doi: 10.1016/j.ajem.2022.03.046. PMID: 35397355
Imaging of Benign Adnexal Disease.
Khati NJ, Kim T, Riess J
Radiol Clin North Am 2020 Mar;58(2):257-273. Epub 2019 Dec 2 doi: 10.1016/j.rcl.2019.10.009. PMID: 32044006
Lesions of the ovary with T1-hypersignal.
Chabrol A, Rousset P, Charlot M, Chateau F, Cotton F, Golfier F, Rety F
Clin Radiol 2014 Oct;69(10):e404-13. Epub 2014 Jul 10 doi: 10.1016/j.crad.2014.05.107. PMID: 25017450

Therapy

Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.
Minneci PC, Bergus KC, Lutz C, Aldrink J, Bence C, Breech L, Dillon PA, Downard C, Ehrlich PF, Fallat M, Fraser JD, Grabowski J, Helmrath M, Hertweck P, Hewitt G, Hirschl RB, Kabre R, Lal DR, Landman M, Leys C, Mak G, Markel T, Pressey J, Raiji M, Rymeski B, Saito J, Sato TT, St Peter SD, Cooper J, Deans K; Midwest Pediatric Surgery Consortium
JAMA 2023 Oct 3;330(13):1247-1254. doi: 10.1001/jama.2023.17183. PMID: 37787794Free PMC Article
Blood biomarkers for the non-invasive diagnosis of endometriosis.
Nisenblat V, Bossuyt PM, Shaikh R, Farquhar C, Jordan V, Scheffers CS, Mol BW, Johnson N, Hull ML
Cochrane Database Syst Rev 2016 May 1;2016(5):CD012179. doi: 10.1002/14651858.CD012179. PMID: 27132058Free PMC Article
Image-guided ovarian mass biopsy: efficacy and safety.
Thabet A, Somarouthu B, Oliva E, Gervais DA, Hahn PF, Lee SI
J Vasc Interv Radiol 2014 Dec;25(12):1922-1927.e1. Epub 2014 Sep 18 doi: 10.1016/j.jvir.2014.08.009. PMID: 25241300
The roles of laparoscopy in treating ovarian cancer.
Lee CL, Kay N, Chen HL, Yen CF, Huang KG
Taiwan J Obstet Gynecol 2009 Mar;48(1):9-14. doi: 10.1016/S1028-4559(09)60029-2. PMID: 19346186
Malignant struma ovarii.
Yassa L, Sadow P, Marqusee E
Nat Clin Pract Endocrinol Metab 2008 Aug;4(8):469-72. Epub 2008 Jun 17 doi: 10.1038/ncpendmet0887. PMID: 18560398

Prognosis

Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.
Minneci PC, Bergus KC, Lutz C, Aldrink J, Bence C, Breech L, Dillon PA, Downard C, Ehrlich PF, Fallat M, Fraser JD, Grabowski J, Helmrath M, Hertweck P, Hewitt G, Hirschl RB, Kabre R, Lal DR, Landman M, Leys C, Mak G, Markel T, Pressey J, Raiji M, Rymeski B, Saito J, Sato TT, St Peter SD, Cooper J, Deans K; Midwest Pediatric Surgery Consortium
JAMA 2023 Oct 3;330(13):1247-1254. doi: 10.1001/jama.2023.17183. PMID: 37787794Free PMC Article
Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.
Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423
Clinical outcomes of fetal ovarian masses diagnosed by prenatal ultrasonography and literature review.
Min J, Tang R, Zhi W, Gu Z, Huang S, Wang J
Medicine (Baltimore) 2022 Oct 14;101(41):e30962. doi: 10.1097/MD.0000000000030962. PMID: 36254031Free PMC Article
Ovarian Torsion in Premenarchal Girls.
Tasset J, Rosen MW, Bell S, Smith YR, Quint EH
J Pediatr Adolesc Gynecol 2019 Jun;32(3):254-258. Epub 2018 Oct 25 doi: 10.1016/j.jpag.2018.10.003. PMID: 30367984
Radiological manifestations of metastasis to the ovary.
Willmott F, Allouni KA, Rockall A
J Clin Pathol 2012 Jul;65(7):585-90. doi: 10.1136/jclinpath-2011-200390. PMID: 22745289

Clinical prediction guides

Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.
Minneci PC, Bergus KC, Lutz C, Aldrink J, Bence C, Breech L, Dillon PA, Downard C, Ehrlich PF, Fallat M, Fraser JD, Grabowski J, Helmrath M, Hertweck P, Hewitt G, Hirschl RB, Kabre R, Lal DR, Landman M, Leys C, Mak G, Markel T, Pressey J, Raiji M, Rymeski B, Saito J, Sato TT, St Peter SD, Cooper J, Deans K; Midwest Pediatric Surgery Consortium
JAMA 2023 Oct 3;330(13):1247-1254. doi: 10.1001/jama.2023.17183. PMID: 37787794Free PMC Article
Adnexal masses during pregnancy: diagnosis, treatment, and prognosis.
Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR
Am J Obstet Gynecol 2023 Jun;228(6):601-612. Epub 2022 Nov 19 doi: 10.1016/j.ajog.2022.11.1291. PMID: 36410423
Imaging of Benign Adnexal Disease.
Khati NJ, Kim T, Riess J
Radiol Clin North Am 2020 Mar;58(2):257-273. Epub 2019 Dec 2 doi: 10.1016/j.rcl.2019.10.009. PMID: 32044006
Ovarian Torsion in Premenarchal Girls.
Tasset J, Rosen MW, Bell S, Smith YR, Quint EH
J Pediatr Adolesc Gynecol 2019 Jun;32(3):254-258. Epub 2018 Oct 25 doi: 10.1016/j.jpag.2018.10.003. PMID: 30367984
Radiological manifestations of metastasis to the ovary.
Willmott F, Allouni KA, Rockall A
J Clin Pathol 2012 Jul;65(7):585-90. doi: 10.1136/jclinpath-2011-200390. PMID: 22745289

Recent systematic reviews

Surgical Management of Adnexal Masses in Pregnancy: A Systematic Review and Meta-analysis.
Cagino K, Li X, Thomas C, Delgado D, Christos P, Acholonu U Jr
J Minim Invasive Gynecol 2021 Jun;28(6):1171-1182.e2. Epub 2021 Jan 28 doi: 10.1016/j.jmig.2021.01.020. PMID: 33515746
Approaches to the management of pediatric ovarian masses in the 21st century: Systematic review and meta-analysis.
Qazi SH, Jeelani SM, Dogar SA, Das JK, Saxena AK
J Pediatr Surg 2020 Mar;55(3):357-368. Epub 2019 Oct 25 doi: 10.1016/j.jpedsurg.2019.09.003. PMID: 31706611
MR imaging in discriminating between benign and malignant paediatric ovarian masses: a systematic review.
van Nimwegen LWE, Mavinkurve-Groothuis AMC, de Krijger RR, Hulsker CCC, Goverde AJ, Zsiros J, Littooij AS
Eur Radiol 2020 Feb;30(2):1166-1181. Epub 2019 Sep 16 doi: 10.1007/s00330-019-06420-4. PMID: 31529256Free PMC Article
Ovarian masses in the child and adolescent: An American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee systematic review.
Renaud EJ, Sømme S, Islam S, Cameron DB, Gates RL, Williams RF, Jancelewicz T, Oyetunji TA, Grabowski J, Diefenbach KA, Baird R, Arnold MA, Lal DR, Shelton J, Guner YS, Gosain A, Kawaguchi AL, Ricca RL, Goldin AB, Dasgupta R
J Pediatr Surg 2019 Mar;54(3):369-377. Epub 2018 Sep 6 doi: 10.1016/j.jpedsurg.2018.08.058. PMID: 30220452
Blood biomarkers for the non-invasive diagnosis of endometriosis.
Nisenblat V, Bossuyt PM, Shaikh R, Farquhar C, Jordan V, Scheffers CS, Mol BW, Johnson N, Hull ML
Cochrane Database Syst Rev 2016 May 1;2016(5):CD012179. doi: 10.1002/14651858.CD012179. PMID: 27132058Free PMC Article

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