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Hordeolum

MedGen UID:
6884
•Concept ID:
C0019917
•
Disease or Syndrome
Synonyms: Hordeola; Hordeolas; Stye; Styes
SNOMED CT: Hordeolum (397513003); Stye (1489008); Sty (1489008)
 
HPO: HP:0010606
Monarch Initiative: MONDO:0005800

Definition

An acute purulent infection of the sebaceous glands of Zeis at the base of the eyelashes, of the apocrine sweat glands of Moll or the meibomian sebacious glands often caused by staphylococcus infections. Hordeola can either occur as Hordeola externa affecting the sebaceous glands of Zeis or the apocrine sweat glands of Moll or as Hordeola interna affecting the meibomian sebacious glands. In contrast to chalazia, hordeola are extremely painful and can cause extreme local swelling. [from HPO]

Professional guidelines

PubMed

Efficacy of azithromycin hydrate ophthalmic solution for treatment of internal hordeolum and meibomitis with or without phlyctenular keratitis.
Shimizu Y, Shinji K, Mitoma K, Kiuchi Y, Chikama T
Jpn J Ophthalmol 2023 Sep;67(5):565-569. Epub 2023 Jul 16 doi: 10.1007/s10384-023-01010-w. PMID: 37453929
Differential Diagnosis of the Swollen Red Eyelid.
Carlisle RT, Digiovanni J
Am Fam Physician 2015 Jul 15;92(2):106-12. PMID: 26176369
Current pattern treatment of hordeolum by ophthalmologists in Thailand.
Panicharoen C, Hirunwiwatkul P
J Med Assoc Thai 2011 Jun;94(6):721-4. PMID: 21696082

Recent clinical studies

Etiology

Efficacy of Care and Antibiotic Use for Chalazia and Hordeola.
Alsoudi AF, Ton L, Ashraf DC, Idowu OO, Kong AW, Wang L, Kersten RC, Winn BJ, Grob SR, Vagefi MR
Eye Contact Lens 2022 Apr 1;48(4):162-168. doi: 10.1097/ICL.0000000000000859. PMID: 35296627Free PMC Article
The Microbiome of Meibomian Gland Secretions from Patients with Internal Hordeolum Treated with Hypochlorous Acid Eyelid Wipes.
Yang S, Wu BC, Cheng Z, Li L, Zhang YP, Zhao H, Zeng HM, Qi DF, Ma ZY, Li JG, Han R, Qu FZ, Luo Y, Liu Y, Chen XL, Dai HM
Dis Markers 2022;2022:7550090. Epub 2022 Feb 24 doi: 10.1155/2022/7550090. PMID: 35251376Free PMC Article
Acupuncture for acute hordeolum.
Cheng K, Law A, Guo M, Wieland LS, Shen X, Lao L
Cochrane Database Syst Rev 2017 Feb 9;2(2):CD011075. doi: 10.1002/14651858.CD011075.pub2. PMID: 28181687Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2013 Apr 30;4(4):CD007742. doi: 10.1002/14651858.CD007742.pub3. PMID: 23633345Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007742. doi: 10.1002/14651858.CD007742.pub2. PMID: 20824865Free PMC Article

Diagnosis

The lowly chalazion.
Kim ES, Afshin EE, Elahi E
Surv Ophthalmol 2023 Jul-Aug;68(4):784-793. Epub 2022 Nov 15 doi: 10.1016/j.survophthal.2022.11.002. PMID: 36395826
Adult Eye Conditions: Common Eye Conditions.
McGinley TC Jr
FP Essent 2022 Aug;519:11-18. PMID: 35947131
Acupuncture for acute hordeolum.
Cheng K, Law A, Guo M, Wieland LS, Shen X, Lao L
Cochrane Database Syst Rev 2017 Feb 9;2(2):CD011075. doi: 10.1002/14651858.CD011075.pub2. PMID: 28181687Free PMC Article
Non-surgical interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2017 Jan 9;1(1):CD007742. doi: 10.1002/14651858.CD007742.pub4. PMID: 28068454Free PMC Article
Differential Diagnosis of the Swollen Red Eyelid.
Carlisle RT, Digiovanni J
Am Fam Physician 2015 Jul 15;92(2):106-12. PMID: 26176369

Therapy

Hordeolum and chalazion.
Rupani SR
JAAPA 2023 Jun 1;36(6):43-44. doi: 10.1097/01.JAA.0000931468.68794.aa. PMID: 37229584
Adult Eye Conditions: Common Eye Conditions.
McGinley TC Jr
FP Essent 2022 Aug;519:11-18. PMID: 35947131
Acupuncture for acute hordeolum.
Cheng K, Law A, Guo M, Wieland LS, Shen X, Lao L
Cochrane Database Syst Rev 2017 Feb 9;2(2):CD011075. doi: 10.1002/14651858.CD011075.pub2. PMID: 28181687Free PMC Article
Non-surgical interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2017 Jan 9;1(1):CD007742. doi: 10.1002/14651858.CD007742.pub4. PMID: 28068454Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2013 Apr 30;4(4):CD007742. doi: 10.1002/14651858.CD007742.pub3. PMID: 23633345Free PMC Article

Prognosis

Ophthalmic Virtual Visit Utilization and Patient Satisfaction During the COVID-19 Pandemic.
Chen DA, Tran AQ, Dinkin MJ, Lelli GJ
Telemed J E Health 2022 Jun;28(6):798-805. Epub 2021 Oct 4 doi: 10.1089/tmj.2021.0392. PMID: 34609934
Incidence of Ophthalmic Disorders in Patients Treated with the Antineoplastic Agent S-1.
Moriya K, Shimizu H, Handa S, Sasaki T, Sasaki Y, Takahashi H, Nakamura S, Yoshida H, Kato Y
Gan To Kagaku Ryoho 2017 Jun;44(6):501-506. PMID: 28698442
Blepharokeratoconjunctivitis in childhood: corneal involvement and visual outcome.
Rodríguez-García A, González-Godínez S, López-Rubio S
Eye (Lond) 2016 Mar;30(3):438-46. Epub 2015 Dec 4 doi: 10.1038/eye.2015.249. PMID: 26634709Free PMC Article
Ocular infection and inflammation.
Mueller JB, McStay CM
Emerg Med Clin North Am 2008 Feb;26(1):57-72, vi. doi: 10.1016/j.emc.2007.10.004. PMID: 18249257
Kaposi's sarcoma of the ocular adnexa.
Brun SC, Jakobiec FA
Int Ophthalmol Clin 1997 Fall;37(4):25-38. doi: 10.1097/00004397-199703740-00004. PMID: 9429930

Clinical prediction guides

Focus on Ophthalmopathology - Orbital Infections from Hordeolum to Necrotizing Fasciitis.
Weller JM, Messmer E
Klin Monbl Augenheilkd 2022 Jul;239(7):886-893. Epub 2022 Jul 20 doi: 10.1055/a-1709-6152. PMID: 35858598
Acupuncture for acute hordeolum.
Cheng K, Law A, Guo M, Wieland LS, Shen X, Lao L
Cochrane Database Syst Rev 2017 Feb 9;2(2):CD011075. doi: 10.1002/14651858.CD011075.pub2. PMID: 28181687Free PMC Article
Non-surgical interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2017 Jan 9;1(1):CD007742. doi: 10.1002/14651858.CD007742.pub4. PMID: 28068454Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2013 Apr 30;4(4):CD007742. doi: 10.1002/14651858.CD007742.pub3. PMID: 23633345Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007742. doi: 10.1002/14651858.CD007742.pub2. PMID: 20824865Free PMC Article

Recent systematic reviews

Acupuncture for acute hordeolum.
Cheng K, Law A, Guo M, Wieland LS, Shen X, Lao L
Cochrane Database Syst Rev 2017 Feb 9;2(2):CD011075. doi: 10.1002/14651858.CD011075.pub2. PMID: 28181687Free PMC Article
Non-surgical interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2017 Jan 9;1(1):CD007742. doi: 10.1002/14651858.CD007742.pub4. PMID: 28068454Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2013 Apr 30;4(4):CD007742. doi: 10.1002/14651858.CD007742.pub3. PMID: 23633345Free PMC Article
Interventions for acute internal hordeolum.
Lindsley K, Nichols JJ, Dickersin K
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007742. doi: 10.1002/14651858.CD007742.pub2. PMID: 20824865Free PMC Article

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