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Persistent infection

MedGen UID:
688822
Concept ID:
C1264606
Disease or Syndrome
Synonyms: Infection, Long Term; Infection, Persistent; Long Term Infection; Long Term Infections; Persistent Infection; Persistent Infections
SNOMED CT: Persistent infection (115648009)

Definition

Infection which lasts for a long period with continuous display of clinical features. Persistent infection arises due to inability of host cells to clear primary infections completely. When persistent infections are cleared so that infection symptoms are under control they are often referred to as chronic infections. LATENT INFECTIONS are infections in which manifestation of clinical symptoms appear later. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPersistent infection

Professional guidelines

PubMed

European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; European Association for the Study of the Liver
J Hepatol 2023 Aug;79(2):433-460. Epub 2023 Jun 24 doi: 10.1016/j.jhep.2023.05.001. PMID: 37364791
Lee C, Song M
J Endod 2022 Sep;48(9):1137-1145. Epub 2022 Jun 14 doi: 10.1016/j.joen.2022.06.002. PMID: 35714726
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567

Recent clinical studies

Etiology

Metersky ML, Barker AF
Clin Chest Med 2022 Mar;43(1):35-46. doi: 10.1016/j.ccm.2021.11.003. PMID: 35236559
Della Fera AN, Warburton A, Coursey TL, Khurana S, McBride AA
Viruses 2021 Feb 20;13(2) doi: 10.3390/v13020321. PMID: 33672465Free PMC Article
Castanheira CP, Sallas ML, Nunes RAL, Lorenzi NPC, Termini L
Pathobiology 2021;88(2):187-197. Epub 2020 Nov 23 doi: 10.1159/000511477. PMID: 33227782
Gal-Mor O
Clin Microbiol Rev 2019 Jan;32(1) Epub 2018 Nov 28 doi: 10.1128/CMR.00088-18. PMID: 30487167Free PMC Article
Camilo V, Sugiyama T, Touati E
Helicobacter 2017 Sep;22 Suppl 1 doi: 10.1111/hel.12405. PMID: 28891130

Diagnosis

European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; European Association for the Study of the Liver
J Hepatol 2023 Aug;79(2):433-460. Epub 2023 Jun 24 doi: 10.1016/j.jhep.2023.05.001. PMID: 37364791
Lamoth F, Calandra T
Eur Respir Rev 2022 Dec 31;31(166) Epub 2022 Nov 29 doi: 10.1183/16000617.0114-2022. PMID: 36450372Free PMC Article
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Gal-Mor O
Clin Microbiol Rev 2019 Jan;32(1) Epub 2018 Nov 28 doi: 10.1128/CMR.00088-18. PMID: 30487167Free PMC Article
Eldin C, Mélenotte C, Mediannikov O, Ghigo E, Million M, Edouard S, Mege JL, Maurin M, Raoult D
Clin Microbiol Rev 2017 Jan;30(1):115-190. doi: 10.1128/CMR.00045-16. PMID: 27856520Free PMC Article

Therapy

Hurlow J, Bowler PG
J Wound Care 2022 May 2;31(5):436-445. doi: 10.12968/jowc.2022.31.5.436. PMID: 35579319
Bernard L, Arvieux C, Brunschweiler B, Touchais S, Ansart S, Bru JP, Oziol E, Boeri C, Gras G, Druon J, Rosset P, Senneville E, Bentayeb H, Bouhour D, Le Moal G, Michon J, Aumaître H, Forestier E, Laffosse JM, Begué T, Chirouze C, Dauchy FA, Devaud E, Martha B, Burgot D, Boutoille D, Stindel E, Dinh A, Bemer P, Giraudeau B, Issartel B, Caille A
N Engl J Med 2021 May 27;384(21):1991-2001. doi: 10.1056/NEJMoa2020198. PMID: 34042388
Feng CH, Mell LK, Sharabi AB, McHale M, Mayadev JS
Semin Radiat Oncol 2020 Oct;30(4):273-280. doi: 10.1016/j.semradonc.2020.05.003. PMID: 32828383
Wang R, Pan W, Jin L, Huang W, Li Y, Wu D, Gao C, Ma D, Liao S
Cancer Lett 2020 Feb 28;471:88-102. Epub 2019 Dec 5 doi: 10.1016/j.canlet.2019.11.039. PMID: 31812696
Manresa C, Sanz-Miralles EC, Twigg J, Bravo M
Cochrane Database Syst Rev 2018 Jan 1;1(1):CD009376. doi: 10.1002/14651858.CD009376.pub2. PMID: 29291254Free PMC Article

Prognosis

Bowden SJ, Doulgeraki T, Bouras E, Markozannes G, Athanasiou A, Grout-Smith H, Kechagias KS, Ellis LB, Zuber V, Chadeau-Hyam M, Flanagan JM, Tsilidis KK, Kalliala I, Kyrgiou M
BMC Med 2023 Jul 27;21(1):274. doi: 10.1186/s12916-023-02965-w. PMID: 37501128Free PMC Article
Zuo X, Zhou R, Yang S, Ma G
J Med Virol 2023 Jan;95(1):e28424. doi: 10.1002/jmv.28424. PMID: 36546414
Quinlan JD
Am Fam Physician 2021 Aug 1;104(2):152-159. PMID: 34383440
Choi IJ, Kim CG, Lee JY, Kim YI, Kook MC, Park B, Joo J
N Engl J Med 2020 Jan 30;382(5):427-436. doi: 10.1056/NEJMoa1909666. PMID: 31995688
Giuliano AR, Palefsky JM, Goldstone S, Moreira ED Jr, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, Chang YH, Ferris D, Rouleau D, Bryan J, Marshall JB, Vuocolo S, Barr E, Radley D, Haupt RM, Guris D
N Engl J Med 2011 Feb 3;364(5):401-11. doi: 10.1056/NEJMoa0909537. PMID: 21288094Free PMC Article

Clinical prediction guides

Noval MG, Spector SN, Bartnicki E, Izzo F, Narula N, Yeung ST, Damani-Yokota P, Dewan MZ, Mezzano V, Rodriguez-Rodriguez BA, Loomis C, Khanna KM, Stapleford KA
Nat Commun 2023 Aug 3;14(1):4668. doi: 10.1038/s41467-023-40047-w. PMID: 37537212Free PMC Article
Lee CY, Shah MK, Hoyos D, Solovyov A, Douglas M, Taur Y, Maslak P, Babady NE, Greenbaum B, Kamboj M, Vardhana SA
Cancer Discov 2022 Jan;12(1):62-73. Epub 2021 Nov 9 doi: 10.1158/2159-8290.CD-21-1033. PMID: 34753749Free PMC Article
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Geng Y, Wang Y
Adv Exp Med Biol 2016;948:39-59. doi: 10.1007/978-94-024-0942-0_3. PMID: 27738978
Thorley-Lawson DA, Hawkins JB, Tracy SI, Shapiro M
Curr Opin Virol 2013 Jun;3(3):227-32. Epub 2013 May 15 doi: 10.1016/j.coviro.2013.04.005. PMID: 23683686Free PMC Article

Recent systematic reviews

Main E, Rand S
Cochrane Database Syst Rev 2023 May 5;5(5):CD002011. doi: 10.1002/14651858.CD002011.pub3. PMID: 37144842Free PMC Article
Norenhag J, Du J, Olovsson M, Verstraelen H, Engstrand L, Brusselaers N
BJOG 2020 Jan;127(2):171-180. Epub 2019 Jul 17 doi: 10.1111/1471-0528.15854. PMID: 31237400
Tamarelle J, Thiébaut ACM, de Barbeyrac B, Bébéar C, Ravel J, Delarocque-Astagneau E
Clin Microbiol Infect 2019 Jan;25(1):35-47. Epub 2018 May 3 doi: 10.1016/j.cmi.2018.04.019. PMID: 29729331Free PMC Article
Arbyn M, Xu L, Simoens C, Martin-Hirsch PP
Cochrane Database Syst Rev 2018 May 9;5(5):CD009069. doi: 10.1002/14651858.CD009069.pub3. PMID: 29740819Free PMC Article
Manresa C, Sanz-Miralles EC, Twigg J, Bravo M
Cochrane Database Syst Rev 2018 Jan 1;1(1):CD009376. doi: 10.1002/14651858.CD009376.pub2. PMID: 29291254Free PMC Article

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