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Pancreatic non-invasive mucinous cystadenocarcinoma

MedGen UID:
690092
Concept ID:
C1266078
Neoplastic Process
Synonyms: Mucinous cystadenocarcinoma, non-invasive; Pancreatic Non-Invasive Mucinous Cystadenocarcinoma; pancreatic non-invasive mucinous cystadenocarcinoma
SNOMED CT: Mucinous cystadenocarcinoma, non-invasive (128900005)
 
Monarch Initiative: MONDO:0004159

Definition

A non-invasive malignant cystic epithelial neoplasm arising from the exocrine pancreas. It occurs almost exclusively in women. Small tumors are usually found incidentally. Larger tumors usually produce symptoms related to compression of the adjacent structures. It is characterized by the presence of columnar, mucin-producing epithelial cells which often form papillary projections with irregular branching and budding. There is cellular stratification, severe dysplasia, and high mitotic activity present. Complete surgical removal is usually associated with an excellent prognosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic non-invasive mucinous cystadenocarcinoma

Recent clinical studies

Etiology

Martel G, Alsharif J, Aubin JM, Marginean C, Mimeault R, Fairfull-Smith RJ, Mohammad WM, Balaa FK
HPB (Oxford) 2013 Aug;15(8):617-22. Epub 2012 Dec 6 doi: 10.1111/hpb.12026. PMID: 23458638Free PMC Article
Gil E, Choi SH, Choi DW, Heo JS, Kim MJ
ANZ J Surg 2013 Dec;83(12):985-90. Epub 2012 Oct 16 doi: 10.1111/j.1445-2197.2012.06295.x. PMID: 23072713
Lahat G, Lubezky N, Haim MB, Nachmany I, Blachar A, Santo I, Nakache R, Klausner JM
Isr Med Assoc J 2011 May;13(5):284-9. PMID: 21845969
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, Sarr MG
Surg Oncol 2011 Jun;20(2):e93-101. Epub 2011 Jan 19 doi: 10.1016/j.suronc.2010.12.003. PMID: 21251815
Fukushima N, Kikuchi Y, Nishiyama T, Kudo A, Fukayama M
Mod Pathol 2008 Aug;21(8):1044-53. Epub 2008 May 16 doi: 10.1038/modpathol.2008.77. PMID: 18487994

Diagnosis

Tezuka S, Ueno M, Kobayashi S, Fukushima T, Nasu R, Washimi K, Yamamoto N, Morinaga S, Morimoto M, Maeda S
Clin J Gastroenterol 2022 Aug;15(4):834-839. Epub 2022 May 11 doi: 10.1007/s12328-022-01639-z. PMID: 35546381Free PMC Article
Martel G, Alsharif J, Aubin JM, Marginean C, Mimeault R, Fairfull-Smith RJ, Mohammad WM, Balaa FK
HPB (Oxford) 2013 Aug;15(8):617-22. Epub 2012 Dec 6 doi: 10.1111/hpb.12026. PMID: 23458638Free PMC Article
Lahat G, Lubezky N, Haim MB, Nachmany I, Blachar A, Santo I, Nakache R, Klausner JM
Isr Med Assoc J 2011 May;13(5):284-9. PMID: 21845969
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, Sarr MG
Surg Oncol 2011 Jun;20(2):e93-101. Epub 2011 Jan 19 doi: 10.1016/j.suronc.2010.12.003. PMID: 21251815
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849

Prognosis

Tezuka S, Ueno M, Kobayashi S, Fukushima T, Nasu R, Washimi K, Yamamoto N, Morinaga S, Morimoto M, Maeda S
Clin J Gastroenterol 2022 Aug;15(4):834-839. Epub 2022 May 11 doi: 10.1007/s12328-022-01639-z. PMID: 35546381Free PMC Article
Lahat G, Lubezky N, Haim MB, Nachmany I, Blachar A, Santo I, Nakache R, Klausner JM
Isr Med Assoc J 2011 May;13(5):284-9. PMID: 21845969
Scarlett CJ, Salisbury EL, Biankin AV, Kench J
Pathology 2011 Apr;43(3):183-200. doi: 10.1097/PAT.0b013e3283445e3a. PMID: 21436628
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, Sarr MG
Surg Oncol 2011 Jun;20(2):e93-101. Epub 2011 Jan 19 doi: 10.1016/j.suronc.2010.12.003. PMID: 21251815
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849

Clinical prediction guides

Tezuka S, Ueno M, Kobayashi S, Fukushima T, Nasu R, Washimi K, Yamamoto N, Morinaga S, Morimoto M, Maeda S
Clin J Gastroenterol 2022 Aug;15(4):834-839. Epub 2022 May 11 doi: 10.1007/s12328-022-01639-z. PMID: 35546381Free PMC Article
Lahat G, Lubezky N, Haim MB, Nachmany I, Blachar A, Santo I, Nakache R, Klausner JM
Isr Med Assoc J 2011 May;13(5):284-9. PMID: 21845969
Scarlett CJ, Salisbury EL, Biankin AV, Kench J
Pathology 2011 Apr;43(3):183-200. doi: 10.1097/PAT.0b013e3283445e3a. PMID: 21436628
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, Sarr MG
Surg Oncol 2011 Jun;20(2):e93-101. Epub 2011 Jan 19 doi: 10.1016/j.suronc.2010.12.003. PMID: 21251815
Fukushima N, Kikuchi Y, Nishiyama T, Kudo A, Fukayama M
Mod Pathol 2008 Aug;21(8):1044-53. Epub 2008 May 16 doi: 10.1038/modpathol.2008.77. PMID: 18487994

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