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Diarrhea-associated hemolytic uremic syndrome

MedGen UID:
692756
Concept ID:
C1268936
Disease or Syndrome
Synonyms: Classic hemolytic uremic syndrome; Diarrhea-associated Hemolytic Uremic Syndrome; Diarrhea-associated HUS (hemolytic uremic syndrome); Epidemic hemolytic uremic syndrome
SNOMED CT: Diarrhea-associated hemolytic uremic syndrome (373421000); Classic hemolytic uremic syndrome (373421000); Epidemic hemolytic uremic syndrome (373421000); Diarrhea-associated HUS (hemolytic uremic syndrome) (373421000)

Definition

Hemolytic uremic syndrome caused by gastrointestinal infection, usually with shiga toxin-producing enterobacteria. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiarrhea-associated hemolytic uremic syndrome

Professional guidelines

PubMed

Iijima K, Kamioka I, Nozu K
Clin Exp Nephrol 2008 Feb;12(1):16-9. Epub 2008 Jan 5 doi: 10.1007/s10157-007-0007-4. PMID: 18175052
Trachtman H, Christen E
Curr Opin Pediatr 1999 Apr;11(2):162-8. doi: 10.1097/00008480-199904000-00011. PMID: 10202627

Recent clinical studies

Etiology

Khalifa NA, Gawish HH, Khalifa NA, Tawfeek DM, Morsy SM
Saudi J Kidney Dis Transpl 2018 Mar-Apr;29(2):303-309. doi: 10.4103/1319-2442.229262. PMID: 29657197
Ninchoji T, Nozu K, Nakanishi K, Horinouchi T, Fujimura J, Yamamura T, Minamikawa S, Ishimori S, Nakanishi K, Yoshikawa N, Morioka I, Kaito H, Iijima K
Clin Exp Nephrol 2017 Oct;21(5):889-894. Epub 2017 Jan 10 doi: 10.1007/s10157-016-1376-3. PMID: 28074307
Nathanson S, Kwon T, Elmaleh M, Charbit M, Launay EA, Harambat J, Brun M, Ranchin B, Bandin F, Cloarec S, Bourdat-Michel G, Piètrement C, Champion G, Ulinski T, Deschênes G
Clin J Am Soc Nephrol 2010 Jul;5(7):1218-28. Epub 2010 May 24 doi: 10.2215/CJN.08921209. PMID: 20498239Free PMC Article
Robson WL, Leung AK, Brant R, Trevenen CL, Stephure DK
Nephron 1995;71(1):54-8. doi: 10.1159/000188674. PMID: 8538849
Robson WL, Leung AK, Fick GH, McKenna AI
Nephron 1992;62(3):296-9. doi: 10.1159/000187063. PMID: 1436342

Diagnosis

Bilkis MD, Bonany P
Arch Argent Pediatr 2021 Feb;119(1):62-66. doi: 10.5546/aap.2021.eng.62. PMID: 33458983
Gupta M, Govindappagari S, Burwick RM
Obstet Gynecol 2020 Jan;135(1):46-58. doi: 10.1097/AOG.0000000000003554. PMID: 31809447Free PMC Article
Wada H, Matsumoto T, Yamashita Y
Semin Thromb Hemost 2014 Nov;40(8):866-73. Epub 2014 Nov 6 doi: 10.1055/s-0034-1395154. PMID: 25377323
Proesmans W
Semin Thromb Hemost 2001 Jun;27(3):201-5. doi: 10.1055/s-2001-15249. PMID: 11446653
Trachtman H, Christen E
Curr Opin Pediatr 1999 Apr;11(2):162-8. doi: 10.1097/00008480-199904000-00011. PMID: 10202627

Therapy

Gupta M, Govindappagari S, Burwick RM
Obstet Gynecol 2020 Jan;135(1):46-58. doi: 10.1097/AOG.0000000000003554. PMID: 31809447Free PMC Article
Zoja C, Buelli S, Morigi M
Pediatr Nephrol 2019 Mar;34(3):379-388. Epub 2017 Dec 6 doi: 10.1007/s00467-017-3850-x. PMID: 29214442
Thomas DE, Elliott EJ
BMC Public Health 2013 Sep 3;13:799. doi: 10.1186/1471-2458-13-799. PMID: 24007265Free PMC Article
Iijima K, Kamioka I, Nozu K
Clin Exp Nephrol 2008 Feb;12(1):16-9. Epub 2008 Jan 5 doi: 10.1007/s10157-007-0007-4. PMID: 18175052
Suri RS, Clark WF, Barrowman N, Mahon JL, Thiessen-Philbrook HR, Rosas-Arellano MP, Zarnke K, Garland JS, Garg AX
Diabetes Care 2005 Oct;28(10):2556-62. doi: 10.2337/diacare.28.10.2556. PMID: 16186301

Prognosis

Iijima K, Kamioka I, Nozu K
Clin Exp Nephrol 2008 Feb;12(1):16-9. Epub 2008 Jan 5 doi: 10.1007/s10157-007-0007-4. PMID: 18175052
Suri RS, Clark WF, Barrowman N, Mahon JL, Thiessen-Philbrook HR, Rosas-Arellano MP, Zarnke K, Garland JS, Garg AX
Diabetes Care 2005 Oct;28(10):2556-62. doi: 10.2337/diacare.28.10.2556. PMID: 16186301
Garg AX, Suri RS, Barrowman N, Rehman F, Matsell D, Rosas-Arellano MP, Salvadori M, Haynes RB, Clark WF
JAMA 2003 Sep 10;290(10):1360-70. doi: 10.1001/jama.290.10.1360. PMID: 12966129
Trachtman H, Christen E
Curr Opin Pediatr 1999 Apr;11(2):162-8. doi: 10.1097/00008480-199904000-00011. PMID: 10202627
Robson WL, Leung AK, Brant R, Trevenen CL, Stephure DK
Nephron 1995;71(1):54-8. doi: 10.1159/000188674. PMID: 8538849

Clinical prediction guides

Tarr GAM, Stokowski T, Shringi S, Tarr PI, Freedman SB, Oltean HN, Rabinowitz PM, Chui L
Toxins (Basel) 2019 Oct 18;11(10) doi: 10.3390/toxins11100607. PMID: 31635282Free PMC Article
Karnisova L, Hradsky O, Blahova K, Fencl F, Dolezel Z, Zaoral T, Zieg J
Eur J Pediatr 2018 Dec;177(12):1837-1844. Epub 2018 Sep 24 doi: 10.1007/s00431-018-3255-2. PMID: 30251107
Suri RS, Clark WF, Barrowman N, Mahon JL, Thiessen-Philbrook HR, Rosas-Arellano MP, Zarnke K, Garland JS, Garg AX
Diabetes Care 2005 Oct;28(10):2556-62. doi: 10.2337/diacare.28.10.2556. PMID: 16186301
Garg AX, Suri RS, Barrowman N, Rehman F, Matsell D, Rosas-Arellano MP, Salvadori M, Haynes RB, Clark WF
JAMA 2003 Sep 10;290(10):1360-70. doi: 10.1001/jama.290.10.1360. PMID: 12966129
Van Geet C, Proesmans W, Arnout J, Vermylen J, Declerck PJ
Kidney Int 1998 Oct;54(4):1324-30. doi: 10.1046/j.1523-1755.1998.00103.x. PMID: 9767551

Recent systematic reviews

Gupta M, Govindappagari S, Burwick RM
Obstet Gynecol 2020 Jan;135(1):46-58. doi: 10.1097/AOG.0000000000003554. PMID: 31809447Free PMC Article
Thomas DE, Elliott EJ
BMC Public Health 2013 Sep 3;13:799. doi: 10.1186/1471-2458-13-799. PMID: 24007265Free PMC Article
Suri RS, Clark WF, Barrowman N, Mahon JL, Thiessen-Philbrook HR, Rosas-Arellano MP, Zarnke K, Garland JS, Garg AX
Diabetes Care 2005 Oct;28(10):2556-62. doi: 10.2337/diacare.28.10.2556. PMID: 16186301
Garg AX, Suri RS, Barrowman N, Rehman F, Matsell D, Rosas-Arellano MP, Salvadori M, Haynes RB, Clark WF
JAMA 2003 Sep 10;290(10):1360-70. doi: 10.1001/jama.290.10.1360. PMID: 12966129

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