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Early neonatal death

MedGen UID:
695583
•Concept ID:
C1271991
•
Finding
Synonyms: Early Neonatal Death; Early Neonatal Mortality
SNOMED CT: Early neonatal death (391181005)

Definition

Death of a live newborn during the first 7 days of life. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly neonatal death

Professional guidelines

PubMed

Preeclampsia management modalities and perinatal death: a retrospective study in Woldia general hospital.
Tlaye KG, Endalfer ML, Kassaw MW, Gebremedhin MM, Aynalem YA
BMC Pregnancy Childbirth 2020 Apr 9;20(1):205. doi: 10.1186/s12884-020-02909-9. PMID: 32272909Free PMC Article
The safety of atovaquone-proguanil for the prevention and treatment of malaria in pregnancy: A systematic review.
Andrejko KL, Mayer RC, Kovacs S, Slutsker E, Bartlett E, Tan KR, Gutman JR
Travel Med Infect Dis 2019 Jan-Feb;27:20-26. Epub 2019 Jan 14 doi: 10.1016/j.tmaid.2019.01.008. PMID: 30654041Free PMC Article
Prenatal Diagnosis of Twin Pregnancies with Complete Hydatidiform Mole and Coexistent Normal Fetus: A Series of 13 Cases.
Giorgione V, Cavoretto P, Cormio G, Valsecchi L, Vimercati A, De Gennaro A, Rabaiotti E, Candiani M, Mangili G
Gynecol Obstet Invest 2017;82(4):404-409. Epub 2016 Aug 13 doi: 10.1159/000448139. PMID: 27522447

Recent clinical studies

Etiology

Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial.
Wennerholm UB, Saltvedt S, Wessberg A, Alkmark M, Bergh C, Wendel SB, Fadl H, Jonsson M, Ladfors L, Sengpiel V, Wesström J, Wennergren G, Wikström AK, Elden H, Stephansson O, Hagberg H
BMJ 2019 Nov 20;367:l6131. doi: 10.1136/bmj.l6131. PMID: 31748223Free PMC Article
Early neonatal death: A challenge worldwide.
Lehtonen L, Gimeno A, Parra-Llorca A, Vento M
Semin Fetal Neonatal Med 2017 Jun;22(3):153-160. Epub 2017 Feb 24 doi: 10.1016/j.siny.2017.02.006. PMID: 28238633
Pregnancy and childbirth outcomes among adolescent mothers: a World Health Organization multicountry study.
Ganchimeg T, Ota E, Morisaki N, Laopaiboon M, Lumbiganon P, Zhang J, Yamdamsuren B, Temmerman M, Say L, Tunçalp Ö, Vogel JP, Souza JP, Mori R; WHO Multicountry Survey on Maternal Newborn Health Research Network
BJOG 2014 Mar;121 Suppl 1:40-8. doi: 10.1111/1471-0528.12630. PMID: 24641534
Alpha-thalassaemia.
Leung WC, Leung KY, Lau ET, Tang MH, Chan V
Semin Fetal Neonatal Med 2008 Aug;13(4):215-22. Epub 2008 Apr 10 doi: 10.1016/j.siny.2008.02.006. PMID: 18406222
Neonatal hemochromatosis.
Knisely AS, Mieli-Vergani G, Whitington PF
Gastroenterol Clin North Am 2003 Sep;32(3):877-89, vi-vii. doi: 10.1016/s0889-8553(03)00050-5. PMID: 14562579

Diagnosis

Repeat placental growth factor-based testing in women with suspected preterm pre-eclampsia (PARROT-2): a multicentre, parallel-group, superiority, randomised controlled trial.
Hurrell A, Webster L, Sparkes J, Battersby C, Brockbank A, Clark K, Duhig KE, Gill C, Green M, Hunter RM, Seed PT, Vowles Z, Myers J, Shennan AH, Chappell LC; PARROT-2 trial group
Lancet 2024 Feb 17;403(10427):619-631. Epub 2024 Feb 8 doi: 10.1016/S0140-6736(23)02357-7. PMID: 38342128
Generalized Pustular Psoriasis in Pregnancy: Current and Future Treatments.
Seishima M, Fujii K, Mizutani Y
Am J Clin Dermatol 2022 Sep;23(5):661-671. Epub 2022 Jun 15 doi: 10.1007/s40257-022-00698-9. PMID: 35704168
Apparent Life-Threatening Events (ALTE): Italian guidelines.
Piumelli R, Davanzo R, Nassi N, Salvatore S, Arzilli C, Peruzzi M, Agosti M, Palmieri A, Paglietti MG, Nosetti L, Pomo R, De Luca F, Rimini A, De Masi S, Costabel S, Cavarretta V, Cremante A, Cardinale F, Cutrera R
Ital J Pediatr 2017 Dec 12;43(1):111. doi: 10.1186/s13052-017-0429-x. PMID: 29233182Free PMC Article
Alpha-thalassaemia.
Leung WC, Leung KY, Lau ET, Tang MH, Chan V
Semin Fetal Neonatal Med 2008 Aug;13(4):215-22. Epub 2008 Apr 10 doi: 10.1016/j.siny.2008.02.006. PMID: 18406222
Neonatal hemochromatosis.
Knisely AS, Mieli-Vergani G, Whitington PF
Gastroenterol Clin North Am 2003 Sep;32(3):877-89, vi-vii. doi: 10.1016/s0889-8553(03)00050-5. PMID: 14562579

Therapy

Repeat placental growth factor-based testing in women with suspected preterm pre-eclampsia (PARROT-2): a multicentre, parallel-group, superiority, randomised controlled trial.
Hurrell A, Webster L, Sparkes J, Battersby C, Brockbank A, Clark K, Duhig KE, Gill C, Green M, Hunter RM, Seed PT, Vowles Z, Myers J, Shennan AH, Chappell LC; PARROT-2 trial group
Lancet 2024 Feb 17;403(10427):619-631. Epub 2024 Feb 8 doi: 10.1016/S0140-6736(23)02357-7. PMID: 38342128
Late-Preterm Antenatal Steroids for Reduction of Neonatal Respiratory Complications: A Randomized Controlled Trial.
Yenuberi H, Ross B, Sasmita Tirkey R, Benjamin SJ, Rathore S, Karuppusami R, Lal A, Thomas N, Mathew JE
Obstet Gynecol 2024 Apr 1;143(4):468-474. Epub 2024 Feb 8 doi: 10.1097/AOG.0000000000005520. PMID: 38330411
Birth spacing and risk of adverse pregnancy and birth outcomes: A systematic review and dose-response meta-analysis.
Ni W, Gao X, Su X, Cai J, Zhang S, Zheng L, Liu J, Feng Y, Chen S, Ma J, Cao W, Zeng F
Acta Obstet Gynecol Scand 2023 Dec;102(12):1618-1633. Epub 2023 Sep 7 doi: 10.1111/aogs.14648. PMID: 37675816Free PMC Article
Hand hygiene for the prevention of infections in neonates.
Kuti BP, Ogunlesi TA, Oduwole O, Oringanje CC, Udoh EE, Bello S, Horn D, Meremikwu MM
Cochrane Database Syst Rev 2023 Jun 6;6(6):CD013326. doi: 10.1002/14651858.CD013326.pub4. PMID: 37278689Free PMC Article
Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial.
Wennerholm UB, Saltvedt S, Wessberg A, Alkmark M, Bergh C, Wendel SB, Fadl H, Jonsson M, Ladfors L, Sengpiel V, Wesström J, Wennergren G, Wikström AK, Elden H, Stephansson O, Hagberg H
BMJ 2019 Nov 20;367:l6131. doi: 10.1136/bmj.l6131. PMID: 31748223Free PMC Article

Prognosis

Late-Preterm Antenatal Steroids for Reduction of Neonatal Respiratory Complications: A Randomized Controlled Trial.
Yenuberi H, Ross B, Sasmita Tirkey R, Benjamin SJ, Rathore S, Karuppusami R, Lal A, Thomas N, Mathew JE
Obstet Gynecol 2024 Apr 1;143(4):468-474. Epub 2024 Feb 8 doi: 10.1097/AOG.0000000000005520. PMID: 38330411
Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial.
Wennerholm UB, Saltvedt S, Wessberg A, Alkmark M, Bergh C, Wendel SB, Fadl H, Jonsson M, Ladfors L, Sengpiel V, Wesström J, Wennergren G, Wikström AK, Elden H, Stephansson O, Hagberg H
BMJ 2019 Nov 20;367:l6131. doi: 10.1136/bmj.l6131. PMID: 31748223Free PMC Article
Apparent Life-Threatening Events (ALTE): Italian guidelines.
Piumelli R, Davanzo R, Nassi N, Salvatore S, Arzilli C, Peruzzi M, Agosti M, Palmieri A, Paglietti MG, Nosetti L, Pomo R, De Luca F, Rimini A, De Masi S, Costabel S, Cavarretta V, Cremante A, Cardinale F, Cutrera R
Ital J Pediatr 2017 Dec 12;43(1):111. doi: 10.1186/s13052-017-0429-x. PMID: 29233182Free PMC Article
Fetal renal impairment.
Vanderheyden T, Kumar S, Fisk NM
Semin Neonatol 2003 Aug;8(4):279-89. doi: 10.1016/S1084-2756(03)00022-8. PMID: 15001131
Neonatal hemochromatosis.
Knisely AS, Mieli-Vergani G, Whitington PF
Gastroenterol Clin North Am 2003 Sep;32(3):877-89, vi-vii. doi: 10.1016/s0889-8553(03)00050-5. PMID: 14562579

Clinical prediction guides

Birth spacing and risk of adverse pregnancy and birth outcomes: A systematic review and dose-response meta-analysis.
Ni W, Gao X, Su X, Cai J, Zhang S, Zheng L, Liu J, Feng Y, Chen S, Ma J, Cao W, Zeng F
Acta Obstet Gynecol Scand 2023 Dec;102(12):1618-1633. Epub 2023 Sep 7 doi: 10.1111/aogs.14648. PMID: 37675816Free PMC Article
Cause and risk factors of early neonatal death in Ethiopia.
Tesfay N, Tariku R, Zenebe A, Dejene Z, Woldeyohannes F
PLoS One 2022;17(9):e0275475. Epub 2022 Sep 29 doi: 10.1371/journal.pone.0275475. PMID: 36174051Free PMC Article
Generalized Pustular Psoriasis in Pregnancy: Current and Future Treatments.
Seishima M, Fujii K, Mizutani Y
Am J Clin Dermatol 2022 Sep;23(5):661-671. Epub 2022 Jun 15 doi: 10.1007/s40257-022-00698-9. PMID: 35704168
Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial.
Wennerholm UB, Saltvedt S, Wessberg A, Alkmark M, Bergh C, Wendel SB, Fadl H, Jonsson M, Ladfors L, Sengpiel V, Wesström J, Wennergren G, Wikström AK, Elden H, Stephansson O, Hagberg H
BMJ 2019 Nov 20;367:l6131. doi: 10.1136/bmj.l6131. PMID: 31748223Free PMC Article
Neonatal hemochromatosis.
Knisely AS, Mieli-Vergani G, Whitington PF
Gastroenterol Clin North Am 2003 Sep;32(3):877-89, vi-vii. doi: 10.1016/s0889-8553(03)00050-5. PMID: 14562579

Recent systematic reviews

Birth spacing and risk of adverse pregnancy and birth outcomes: A systematic review and dose-response meta-analysis.
Ni W, Gao X, Su X, Cai J, Zhang S, Zheng L, Liu J, Feng Y, Chen S, Ma J, Cao W, Zeng F
Acta Obstet Gynecol Scand 2023 Dec;102(12):1618-1633. Epub 2023 Sep 7 doi: 10.1111/aogs.14648. PMID: 37675816Free PMC Article
Hand hygiene for the prevention of infections in neonates.
Kuti BP, Ogunlesi TA, Oduwole O, Oringanje CC, Udoh EE, Bello S, Horn D, Meremikwu MM
Cochrane Database Syst Rev 2023 Jun 6;6(6):CD013326. doi: 10.1002/14651858.CD013326.pub4. PMID: 37278689Free PMC Article
Hand hygiene for the prevention of infections in neonates.
Kuti BP, Ogunlesi TA, Oduwole O, Oringanje C, Udoh EE, Meremikwu MM
Cochrane Database Syst Rev 2021 Jan 20;1(1):CD013326. doi: 10.1002/14651858.CD013326.pub2. PMID: 33471367Free PMC Article
Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.
Siemieniuk RA, Foroutan F, Mirza R, Mah Ming J, Alexander PE, Agarwal A, Lesi O, Merglen A, Chang Y, Zhang Y, Mir H, Hepworth E, Lee Y, Zeraatkar D, Guyatt GH
BMJ Open 2017 Sep 11;7(9):e019022. doi: 10.1136/bmjopen-2017-019022. PMID: 28893758Free PMC Article
Maternal healthcare in migrants: a systematic review.
Almeida LM, Caldas J, Ayres-de-Campos D, Salcedo-Barrientos D, Dias S
Matern Child Health J 2013 Oct;17(8):1346-54. doi: 10.1007/s10995-012-1149-x. PMID: 23334357

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