U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Secondary cataract

MedGen UID:
726896
•Concept ID:
C1306068
•
Disease or Syndrome
Synonyms: Capsule Opacification; Capsule Opacifications; Cataract, Secondary; Cataracts, Secondary; Opacification, Capsule; Opacifications, Capsule; Secondary Cataract; Secondary Cataracts
SNOMED CT: Secondary cataract (766834007); After-cataract (766834007); Posterior capsular opacification (766834007)

Definition

Clouding or loss of transparency of the posterior lens capsule, usually following CATARACT extraction. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSecondary cataract

Professional guidelines

PubMed

Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Adult retinopathy of prematurity: treatment implications, long term sequelae, and management.
Chang E, Rao P
Curr Opin Ophthalmol 2021 Sep 1;32(5):489-493. doi: 10.1097/ICU.0000000000000787. PMID: 34231528
Update on the Treatment of Uveitis in Patients with Juvenile Idiopathic Arthritis: A Review.
Asproudis I, Katsanos A, Kozeis N, Tantou A, Konstas AG
Adv Ther 2017 Dec;34(12):2558-2565. Epub 2017 Nov 16 doi: 10.1007/s12325-017-0635-3. PMID: 29143927

Recent clinical studies

Etiology

Hydroxychloroquine is neutral on incidental cataracts in patients with rheumatoid arthritis.
Zhang Z, Ma X, Wang YH, Shi X, Wei JC
Sci Rep 2023 Apr 5;13(1):5576. doi: 10.1038/s41598-023-32297-x. PMID: 37019978Free PMC Article
Risk factors affecting cataract surgery outcome: The Malaysian cataract surgery registry.
Yong GY, Mohamed-Noor J, Salowi MA, Adnan TH, Zahari M
PLoS One 2022;17(9):e0274939. Epub 2022 Sep 21 doi: 10.1371/journal.pone.0274939. PMID: 36129906Free PMC Article
Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Outcomes of Cataract Surgery Following Treatment for Retinoblastoma.
Kim HM, Lee BJ, Kim JH, Yu YS
Korean J Ophthalmol 2017 Feb;31(1):52-57. Epub 2017 Feb 2 doi: 10.3341/kjo.2017.31.1.52. PMID: 28243024Free PMC Article
Pseudoexfoliation syndrome and secondary cataract.
Küchle M, Amberg A, Martus P, Nguyen NX, Naumann GO
Br J Ophthalmol 1997 Oct;81(10):862-6. doi: 10.1136/bjo.81.10.862. PMID: 9486027Free PMC Article

Diagnosis

Hydroxychloroquine is neutral on incidental cataracts in patients with rheumatoid arthritis.
Zhang Z, Ma X, Wang YH, Shi X, Wei JC
Sci Rep 2023 Apr 5;13(1):5576. doi: 10.1038/s41598-023-32297-x. PMID: 37019978Free PMC Article
Presence of cataract in patients treated for retinoblastoma at the national institute of pediatrics in Mexico (2011-2021).
Sánchez-Cañal B, Bosch Canto V
J Fr Ophtalmol 2023 Mar;46(3):216-222. Epub 2023 Jan 13 doi: 10.1016/j.jfo.2022.06.018. PMID: 36642598
Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Outcomes of Cataract Surgery Following Treatment for Retinoblastoma.
Kim HM, Lee BJ, Kim JH, Yu YS
Korean J Ophthalmol 2017 Feb;31(1):52-57. Epub 2017 Feb 2 doi: 10.3341/kjo.2017.31.1.52. PMID: 28243024Free PMC Article
Kniest syndrome.
Subramanian S, Gamanagatti S, Sinha A, Sampangi R
Indian Pediatr 2007 Dec;44(12):931-3. PMID: 18175850

Therapy

Hydroxychloroquine is neutral on incidental cataracts in patients with rheumatoid arthritis.
Zhang Z, Ma X, Wang YH, Shi X, Wei JC
Sci Rep 2023 Apr 5;13(1):5576. doi: 10.1038/s41598-023-32297-x. PMID: 37019978Free PMC Article
Risk factors affecting cataract surgery outcome: The Malaysian cataract surgery registry.
Yong GY, Mohamed-Noor J, Salowi MA, Adnan TH, Zahari M
PLoS One 2022;17(9):e0274939. Epub 2022 Sep 21 doi: 10.1371/journal.pone.0274939. PMID: 36129906Free PMC Article
Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Outcomes of Cataract Surgery Following Treatment for Retinoblastoma.
Kim HM, Lee BJ, Kim JH, Yu YS
Korean J Ophthalmol 2017 Feb;31(1):52-57. Epub 2017 Feb 2 doi: 10.3341/kjo.2017.31.1.52. PMID: 28243024Free PMC Article
Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.
Lovicu FJ, Shin EH, McAvoy JW
Exp Eye Res 2016 Jan;142:92-101. Epub 2015 May 21 doi: 10.1016/j.exer.2015.02.004. PMID: 26003864Free PMC Article

Prognosis

Hydroxychloroquine is neutral on incidental cataracts in patients with rheumatoid arthritis.
Zhang Z, Ma X, Wang YH, Shi X, Wei JC
Sci Rep 2023 Apr 5;13(1):5576. doi: 10.1038/s41598-023-32297-x. PMID: 37019978Free PMC Article
Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168
Bag-in-the-lens intraocular lens in paediatric cataract surgery: intraoperative and postoperative outcomes.
Boonstra NE, Haugen OH
Acta Ophthalmol 2022 Feb;100(1):e135-e141. Epub 2021 May 5 doi: 10.1111/aos.14878. PMID: 33949791
Visual and Refractive Outcomes of Children After Early Secondary Cataract Extraction Following Wound Repair for Penetrating Ocular Trauma.
Arora K, Arora P, Ganesh S, Gupta S, Das RR
J Pediatr Ophthalmol Strabismus 2018 Mar 1;55(2):122-127. Epub 2017 Nov 14 doi: 10.3928/01913913-20170703-04. PMID: 29131915
Outcomes of Cataract Surgery Following Treatment for Retinoblastoma.
Kim HM, Lee BJ, Kim JH, Yu YS
Korean J Ophthalmol 2017 Feb;31(1):52-57. Epub 2017 Feb 2 doi: 10.3341/kjo.2017.31.1.52. PMID: 28243024Free PMC Article

Clinical prediction guides

Hydroxychloroquine is neutral on incidental cataracts in patients with rheumatoid arthritis.
Zhang Z, Ma X, Wang YH, Shi X, Wei JC
Sci Rep 2023 Apr 5;13(1):5576. doi: 10.1038/s41598-023-32297-x. PMID: 37019978Free PMC Article
Presence of cataract in patients treated for retinoblastoma at the national institute of pediatrics in Mexico (2011-2021).
Sánchez-Cañal B, Bosch Canto V
J Fr Ophtalmol 2023 Mar;46(3):216-222. Epub 2023 Jan 13 doi: 10.1016/j.jfo.2022.06.018. PMID: 36642598
Conjunctival Epithelial Ingrowth After Penetrating Keratoplasty.
Hata-Mizuno M, Ingaki E, Mitamura H, Uchino Y, Tsubota K, Shimmura S
Cornea 2020 Sep;39(9):1181-1183. doi: 10.1097/ICO.0000000000002316. PMID: 32341316
Pseudoexfoliation syndrome and secondary cataract.
Küchle M, Amberg A, Martus P, Nguyen NX, Naumann GO
Br J Ophthalmol 1997 Oct;81(10):862-6. doi: 10.1136/bjo.81.10.862. PMID: 9486027Free PMC Article
The pathology of after-cataract. A minireview.
Kappelhof JP, Vrensen GF
Acta Ophthalmol Suppl (1985) 1992;(205):13-24. doi: 10.1111/j.1755-3768.1992.tb02176.x. PMID: 1332409

Recent systematic reviews

Pediatric Cataract Surgery Following Treatment for Retinoblastoma: A Case Series and Systematic Review.
Kletke SN, Mallipatna A, Mireskandari K, Gallie BL, Ali A
Am J Ophthalmol 2022 Jul;239:130-141. Epub 2022 Feb 13 doi: 10.1016/j.ajo.2022.02.001. PMID: 35172168

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...