U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neoplasm of the larynx

MedGen UID:
7271
•Concept ID:
C0023055
•
Neoplastic Process
Synonyms: Laryngeal Neoplasm; Laryngeal Neoplasms; Larynx Neoplasm; Larynx Neoplasms; Neoplasm, Laryngeal; Neoplasm, Larynx; Neoplasms, Laryngeal; Neoplasms, Larynx
SNOMED CT: Neoplasm of larynx (126692004); Tumor of larynx (126692004)
 
HPO: HP:0100605
Monarch Initiative: MONDO:0021071

Definition

A benign or malignant neoplasm involving the larynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of the larynx

Professional guidelines

PubMed

High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.
Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer M, Grant N, Thomas C, Schlegel R, Yuan H
Papillomavirus Res 2019 Dec;8:100181. Epub 2019 Aug 22 doi: 10.1016/j.pvr.2019.100181. PMID: 31446060Free PMC Article
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists.
Manickavasagam J, Wu K, Bateman ND
J Laryngol Otol 2013 Sep;127(9):917-21. Epub 2013 Aug 8 doi: 10.1017/S0022215113001588. PMID: 23927772
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276

Curated

NCCN, Head and Neck, 2.2022

Recent clinical studies

Etiology

Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Laryngeal solitary fibrous tumour.
Stomeo F, Padovani D, Bozzo C, Pastore A
Auris Nasus Larynx 2007 Sep;34(3):405-8. Epub 2007 Mar 6 doi: 10.1016/j.anl.2007.01.001. PMID: 17337142
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Chondrosarcoma of the larynx: challenges in diagnosis and management.
Bogdan CJ, Maniglia AJ, Eliachar I, Katz RL
Head Neck 1994 Mar-Apr;16(2):127-34. doi: 10.1002/hed.2880160205. PMID: 8021131
Spindle cell carcinoma of the larynx.
Hyams VJ
Can J Otolaryngol 1975;4(2):307-13. PMID: 1139427

Diagnosis

High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.
Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer M, Grant N, Thomas C, Schlegel R, Yuan H
Papillomavirus Res 2019 Dec;8:100181. Epub 2019 Aug 22 doi: 10.1016/j.pvr.2019.100181. PMID: 31446060Free PMC Article
Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Recurrent respiratory papillomatosis: a review.
Derkay CS, Wiatrak B
Laryngoscope 2008 Jul;118(7):1236-47. doi: 10.1097/MLG.0b013e31816a7135. PMID: 18496162
Diagnostic procedures for detection of lymph node metastases in cancer of the larynx.
Kau RJ, Alexiou C, Stimmer H, Arnold W
ORL J Otorhinolaryngol Relat Spec 2000 Jul-Aug;62(4):199-203. doi: 10.1159/000027746. PMID: 10859520
Non-epithelial malignant neoplasms of the larynx.
Narozny W, Ozdziński W, Mikaszewski B
Auris Nasus Larynx 1994;21(3):178-80. doi: 10.1016/s0385-8146(12)80141-6. PMID: 7872894

Therapy

Systemic bevacizumab as adjuvant therapy for recurrent respiratory papillomatosis in children: A series of three pediatric cases and literature review.
Enrique OH, Eloy SH, Adrian TP, Perla V
Am J Otolaryngol 2021 Sep-Oct;42(5):103126. Epub 2021 Jun 24 doi: 10.1016/j.amjoto.2021.103126. PMID: 34175693
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists.
Manickavasagam J, Wu K, Bateman ND
J Laryngol Otol 2013 Sep;127(9):917-21. Epub 2013 Aug 8 doi: 10.1017/S0022215113001588. PMID: 23927772
Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Spindle cell carcinoma of the larynx with a verrucous carcinoma component: combined carcinoma of larynx.
Karahatay S, Yilmaz YF, Gunhan O, Birkent H, Yetiser S
Auris Nasus Larynx 2007 Dec;34(4):557-9. Epub 2007 May 7 doi: 10.1016/j.anl.2007.02.006. PMID: 17485187
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276

Prognosis

Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Spindle cell carcinoma of the larynx with a verrucous carcinoma component: combined carcinoma of larynx.
Karahatay S, Yilmaz YF, Gunhan O, Birkent H, Yetiser S
Auris Nasus Larynx 2007 Dec;34(4):557-9. Epub 2007 May 7 doi: 10.1016/j.anl.2007.02.006. PMID: 17485187
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Diagnostic procedures for detection of lymph node metastases in cancer of the larynx.
Kau RJ, Alexiou C, Stimmer H, Arnold W
ORL J Otorhinolaryngol Relat Spec 2000 Jul-Aug;62(4):199-203. doi: 10.1159/000027746. PMID: 10859520
Ventriculosaccular lymphoepithelioma of the larynx: case report and literature review.
Narozny W, Betlejewski A, Stankiewicz C, Kamiński M
Head Neck 1998 Aug;20(5):425-9. doi: 10.1002/(sici)1097-0347(199808)20:5<425::aid-hed11>3.0.co;2-f. PMID: 9663671

Clinical prediction guides

Risk Factors for Dysplasia in Recurrent Respiratory Papillomatosis in an Adult and Pediatric Population.
Karatayli-Ozgursoy S, Bishop JA, Hillel A, Akst L, Best SR
Ann Otol Rhinol Laryngol 2016 Mar;125(3):235-41. Epub 2015 Oct 8 doi: 10.1177/0003489415608196. PMID: 26453486
Histologic correlation of expression of Ki-67 in squamous cell carcinoma of the glottis according to the degree of cell differentiation.
Bonhin RG, Carvalho GM, Guimarães AC, Chone CT, Crespo AN, Altemani AM, Amstalden EM
Braz J Otorhinolaryngol 2014 Jul-Aug;80(4):290-5. Epub 2014 Jun 11 doi: 10.1016/j.bjorl.2014.05.016. PMID: 25183178Free PMC Article
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Ventriculosaccular lymphoepithelioma of the larynx: case report and literature review.
Narozny W, Betlejewski A, Stankiewicz C, Kamiński M
Head Neck 1998 Aug;20(5):425-9. doi: 10.1002/(sici)1097-0347(199808)20:5<425::aid-hed11>3.0.co;2-f. PMID: 9663671

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...