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Amebic liver abscess

MedGen UID:
7366
•Concept ID:
C0023886
•
Disease or Syndrome
Synonyms: Abscess, Amebic Liver; Abscess, Amebic, Hepatic; Abscess, Amoebic Hepatic; Abscess, Amoebic Liver; Abscess, Hepatic, Amebic; Abscess, Liver, Amebic; Abscesses, Amebic Liver; Abscesses, Amoebic Hepatic; Abscesses, Amoebic Liver; Amebiasis, Hepatic; Amebic Liver Abscess; Amebic Liver Abscesses; Amoebiasis, Hepatic; Amoebic Hepatic Abscess; Amoebic Hepatic Abscesses; Amoebic Liver Abscess; Amoebic Liver Abscesses; Hepatic Abscess, Amoebic; Hepatic Abscesses, Amoebic; Hepatic Amebiasis; Hepatic Amoebiasis; Liver Abscess, Amebic; Liver Abscess, Amoebic; Liver Abscesses, Amebic; Liver Abscesses, Amoebic
SNOMED CT: ALA - Amebic liver abscess (75119003); Amebic liver abscess (75119003)

Definition

Single or multiple areas of PUS due to infection by any ameboid protozoa (AMEBIASIS). A common form is caused by the ingestion of ENTAMOEBA HISTOLYTICA. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmebic liver abscess

Professional guidelines

PubMed

Clinical and Endoscopic Management of Synchronous Amoebic Liver Abscess and Bleeding Colonic Ulcers.
Premkumar M, Devurgowda D, Dudha S, Kulkarni A, Joshi YK
J Assoc Physicians India 2019 Mar;67(3):14-18. PMID: 31304698
Flavonoids as a Natural Treatment Against Entamoeba histolytica.
Martínez-Castillo M, Pacheco-Yepez J, Flores-Huerta N, Guzmán-Téllez P, Jarillo-Luna RA, Cárdenas-Jaramillo LM, Campos-Rodríguez R, Shibayama M
Front Cell Infect Microbiol 2018;8:209. Epub 2018 Jun 22 doi: 10.3389/fcimb.2018.00209. PMID: 29988403Free PMC Article
Management of amebic and pyogenic liver abscess.
Sharma MP, Ahuja V
Indian J Gastroenterol 2001 Mar;20 Suppl 1:C33-6. PMID: 11293176

Recent clinical studies

Etiology

Amebiasis and Amebic Liver Abscess in Children.
Gupta S, Smith L, Diakiw A
Pediatr Clin North Am 2022 Feb;69(1):79-97. doi: 10.1016/j.pcl.2021.08.003. PMID: 34794678
Flavonoids as a Natural Treatment Against Entamoeba histolytica.
Martínez-Castillo M, Pacheco-Yepez J, Flores-Huerta N, Guzmán-Téllez P, Jarillo-Luna RA, Cárdenas-Jaramillo LM, Campos-Rodríguez R, Shibayama M
Front Cell Infect Microbiol 2018;8:209. Epub 2018 Jun 22 doi: 10.3389/fcimb.2018.00209. PMID: 29988403Free PMC Article
Amebic liver abscess.
Hughes MA, Petri WA Jr
Infect Dis Clin North Am 2000 Sep;14(3):565-82, viii. doi: 10.1016/s0891-5520(05)70121-5. PMID: 10987110
Amebic liver abscess.
Fujihara T, Nagai Y, Kubo T, Seki S, Satake K
J Gastroenterol 1996 Oct;31(5):659-63. doi: 10.1007/BF02347613. PMID: 8887031
Metronidazole.
Finegold SM
Ann Intern Med 1980 Oct;93(4):585-7. doi: 10.7326/0003-4819-93-4-585. PMID: 7436193

Diagnosis

Amebiasis and Amebic Liver Abscess in Children.
Gupta S, Smith L, Diakiw A
Pediatr Clin North Am 2022 Feb;69(1):79-97. doi: 10.1016/j.pcl.2021.08.003. PMID: 34794678
Pyogenic and Amebic Infections of the Liver.
Roediger R, Lisker-Melman M
Gastroenterol Clin North Am 2020 Jun;49(2):361-377. doi: 10.1016/j.gtc.2020.01.013. PMID: 32389368
Amebic Liver Abscess.
Wang HH, Lin WR
N Engl J Med 2018 Dec 6;379(23):2255. doi: 10.1056/NEJMicm1800360. PMID: 30575458
Amebic liver abscess.
Wells CD, Arguedas M
South Med J 2004 Jul;97(7):673-82. doi: 10.1097/00007611-200407000-00013. PMID: 15301125
Hepatic amebiasis.
Salles JM, Moraes LA, Salles MC
Braz J Infect Dis 2003 Apr;7(2):96-110. Epub 2003 Nov 19 doi: 10.1590/s1413-86702003000200002. PMID: 12959680

Therapy

Amebiasis and Amebic Liver Abscess in Children.
Gupta S, Smith L, Diakiw A
Pediatr Clin North Am 2022 Feb;69(1):79-97. doi: 10.1016/j.pcl.2021.08.003. PMID: 34794678
Pyogenic and Amebic Infections of the Liver.
Roediger R, Lisker-Melman M
Gastroenterol Clin North Am 2020 Jun;49(2):361-377. doi: 10.1016/j.gtc.2020.01.013. PMID: 32389368
Liver abscess: diagnostic and management issues found in the low resource setting.
Khim G, Em S, Mo S, Townell N
Br Med Bull 2019 Dec 11;132(1):45-52. doi: 10.1093/bmb/ldz032. PMID: 31836890Free PMC Article
Amebic liver abscess.
Fujihara T, Nagai Y, Kubo T, Seki S, Satake K
J Gastroenterol 1996 Oct;31(5):659-63. doi: 10.1007/BF02347613. PMID: 8887031
Metronidazole.
Finegold SM
Ann Intern Med 1980 Oct;93(4):585-7. doi: 10.7326/0003-4819-93-4-585. PMID: 7436193

Prognosis

Pyogenic and Amebic Infections of the Liver.
Roediger R, Lisker-Melman M
Gastroenterol Clin North Am 2020 Jun;49(2):361-377. doi: 10.1016/j.gtc.2020.01.013. PMID: 32389368
Liver abscess: diagnostic and management issues found in the low resource setting.
Khim G, Em S, Mo S, Townell N
Br Med Bull 2019 Dec 11;132(1):45-52. doi: 10.1093/bmb/ldz032. PMID: 31836890Free PMC Article
Hepatic amebiasis.
Salles JM, Moraes LA, Salles MC
Braz J Infect Dis 2003 Apr;7(2):96-110. Epub 2003 Nov 19 doi: 10.1590/s1413-86702003000200002. PMID: 12959680
Amebic liver abscess.
Hughes MA, Petri WA Jr
Infect Dis Clin North Am 2000 Sep;14(3):565-82, viii. doi: 10.1016/s0891-5520(05)70121-5. PMID: 10987110
Amebic liver abscess.
Fujihara T, Nagai Y, Kubo T, Seki S, Satake K
J Gastroenterol 1996 Oct;31(5):659-63. doi: 10.1007/BF02347613. PMID: 8887031

Clinical prediction guides

Updates on the worldwide burden of amoebiasis: A case series and literature review.
Nasrallah J, Akhoundi M, Haouchine D, Marteau A, Mantelet S, Wind P, Benamouzig R, Bouchaud O, Dhote R, Izri A
J Infect Public Health 2022 Oct;15(10):1134-1141. Epub 2022 Aug 30 doi: 10.1016/j.jiph.2022.08.013. PMID: 36155852
Current Status of Amebic Liver Abscess in Korea Comparing with Pyogenic Liver Abscess.
Kim E, Park DH, Kim KJ, Kim TO, Park SH, Park J, Choi JH, Lee J, Park YE, Oh EH, Hwang JS, Heo NY
Korean J Gastroenterol 2020 Jul 25;76(1):28-36. doi: 10.4166/kjg.2020.76.1.28. PMID: 32703917
Venous thrombosis and segmental hypoperfusion in amebic liver abscess: MDCT demonstration and its implications.
Priyadarshi RN, Kumar P, Kumar R, Anand U, Shyama
Abdom Radiol (NY) 2020 Mar;45(3):652-660. doi: 10.1007/s00261-020-02409-6. PMID: 31955219
Areas of research and clinical approaches to the study of liver abscess.
González-Alcaide G, Peris J, Ramos JM
World J Gastroenterol 2017 Jan 14;23(2):357-365. doi: 10.3748/wjg.v23.i2.357. PMID: 28127209Free PMC Article
Varied Clinical Manifestations of Amebic Colitis.
Cooper CJ, Fleming R, Boman DA, Zuckerman MJ
South Med J 2015 Nov;108(11):676-81. doi: 10.14423/SMJ.0000000000000370. PMID: 26539949

Recent systematic reviews

Prevalence of Amoebiasis and Associated Complications in India: A Systematic Review.
Gupta P, Singh KK, Balodhi A, Jain K, Deeba F, Salam N
Acta Parasitol 2022 Jun;67(2):947-961. Epub 2022 Apr 11 doi: 10.1007/s11686-022-00547-z. PMID: 35404011
Evidence-based therapeutic dilemma in the management of uncomplicated amebic liver abscess: A systematic review and meta-analysis.
Kumar R, Ranjan A, Narayan R, Priyadarshi RN, Anand U, Shalimar
Indian J Gastroenterol 2019 Dec;38(6):498-508. Epub 2020 Jan 21 doi: 10.1007/s12664-019-01004-y. PMID: 31965537
Persistent febrile illnesses in Nepal: A systematic review.
Koirala KD, Chappuis F, Verdonck K, Rijal S, Boelaert M
Indian J Med Res 2018 Oct;148(4):385-395. doi: 10.4103/ijmr.IJMR_505_18. PMID: 30666001Free PMC Article
Colonoscopic diagnosis of amebiasis: a case series and systematic review.
Lee KC, Lu CC, Hu WH, Lin SE, Chen HH
Int J Colorectal Dis 2015 Jan;30(1):31-41. Epub 2014 Oct 28 doi: 10.1007/s00384-014-2040-6. PMID: 25346004
Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess.
Chavez-Tapia NC, Hernandez-Calleros J, Tellez-Avila FI, Torre A, Uribe M
Cochrane Database Syst Rev 2009 Jan 21;(1):CD004886. doi: 10.1002/14651858.CD004886.pub2. PMID: 19160244

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