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Malaria, Avian

MedGen UID:
7444
•Concept ID:
C0024533
•
Disease or Syndrome
Synonyms: Avian Malaria; Avian Malarias; Malarias, Avian

Definition

Any of a group of infections of fowl caused by protozoa of the genera PLASMODIUM, Leucocytozoon, and Haemoproteus. The life cycles of these parasites and the disease produced bears strong resemblance to those observed in human malaria. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalaria, Avian

Professional guidelines

PubMed

The use of avian malaria for the discovery of drugs effective in the treatment and prevention of human malaria; drugs for clinical treatment and clinical prophylaxis.
DAVEY DG
Ann Trop Med Parasitol 1946 Apr;40:52-73. doi: 10.1080/00034983.1946.11685262. PMID: 20984393

Recent clinical studies

Etiology

Changes in hypothalamic-pituitary-adrenal axis function, immunity, and glucose during acute Plasmodium relictum infection in house sparrows (Passer domesticus).
Kelly TR, Cannon AL, Stansberry KR, Kimball MG, Lattin CR
Gen Comp Endocrinol 2024 Jan 1;345:114388. Epub 2023 Oct 4 doi: 10.1016/j.ygcen.2023.114388. PMID: 37802425
Prevalence and genetic diversity of avian haemosporidian parasites in islands within a mega hydroelectric dam in the Brazilian Amazon.
Anjos CC, Bicudo T, Fecchio A, Anciães M, Mathias BS, Chagas CRF, Bell JA, Guimarães LO, Monteiro EF, Kirchgatter K
Parasitol Res 2023 Sep;122(9):2065-2077. Epub 2023 Jul 1 doi: 10.1007/s00436-023-07906-3. PMID: 37391644
Plasmodium relictum infection in Culex quinquefasciatus (Culicidae) decreases diel flight activity but increases peak dusk flight activity.
Adams DR, Golnar AJ, Meyers JI, Slotman MA, Hamer GL
Malar J 2022 Aug 22;21(1):244. doi: 10.1186/s12936-022-04265-9. PMID: 35996189Free PMC Article
Ecological Effects on the Dynamics of West Nile Virus and Avian Plasmodium: The Importance of Mosquito Communities and Landscape.
Ferraguti M, Martínez-de la Puente J, Figuerola J
Viruses 2021 Jun 23;13(7) doi: 10.3390/v13071208. PMID: 34201673Free PMC Article
Molecular detection of vector-borne pathogens from mosquitoes collected in two zoological gardens in Germany.
Heym EC, Kampen H, Krone O, Schäfer M, Werner D
Parasitol Res 2019 Jul;118(7):2097-2105. Epub 2019 Jun 1 doi: 10.1007/s00436-019-06327-5. PMID: 31154526Free PMC Article

Diagnosis

Stress in paradise: effects of elevated corticosterone on immunity and avian malaria resilience in a Hawaiian passerine.
Names GR, Schultz EM, Krause JS, Hahn TP, Wingfield JC, Heal M, Cornelius JM, Klasing KC, Hunt KE
J Exp Biol 2021 Oct 15;224(20) Epub 2021 Oct 19 doi: 10.1242/jeb.242951. PMID: 34553762Free PMC Article
Avian and simian malaria: do they have a cancer connection?
Ward M, Benelli G
Parasitol Res 2017 Mar;116(3):839-845. Epub 2016 Dec 26 doi: 10.1007/s00436-016-5352-3. PMID: 28019000
Two functionally distinct organic osmolyte pathways in Plasmodium gallinaceum-infected chicken red blood cells.
Staines HM, Godfrey EM, Lapaix F, Egee S, Thomas S, Ellory JC
Biochim Biophys Acta 2002 Mar 19;1561(1):98-108. doi: 10.1016/s0005-2736(01)00461-8. PMID: 11988184
A PCR test for avian malaria in Hawaiian birds.
Feldman RA, Freed LA, Cann RL
Mol Ecol 1995 Dec;4(6):663-73. doi: 10.1111/j.1365-294x.1995.tb00267.x. PMID: 8564006
Malaria.
Field JW
Trop Dis Bull 1968 Apr;65(4):353-91 contd. PMID: 4870319

Therapy

Mosquitoes in the Danube Delta: searching for vectors of filarioid helminths and avian malaria.
Ionică AM, Zittra C, Wimmer V, Leitner N, Votýpka J, Modrý D, Mihalca AD, Fuehrer HP
Parasit Vectors 2017 Jul 5;10(1):324. doi: 10.1186/s13071-017-2264-8. PMID: 28679443Free PMC Article
Can the host immune system promote multiple invasions of erythrocytes in vivo? Differential effects of medication and host sex in a wild malaria-like model.
Martínez-de la Puente J, Merino S, Tomás G, Moreno J, Morales J, Lobato E, García-Fraile S
Parasitology 2007 May;134(Pt 5):651-5. Epub 2006 Dec 4 doi: 10.1017/S003118200600196X. PMID: 17140465
Measuring the effects of an ever-changing environment on malaria control.
McCutchan TF, Grim KC, Li J, Weiss W, Rathore D, Sullivan M, Graczyk TK, Kumar S, Cranfield MR
Infect Immun 2004 Apr;72(4):2248-53. doi: 10.1128/IAI.72.4.2248-2253.2004. PMID: 15039349Free PMC Article
Transmission-blocking vaccines.
Kaslow DC
Chem Immunol 2002;80:287-307. doi: 10.1159/000058850. PMID: 12058646
Malaria.
Field JW
Trop Dis Bull 1968 Apr;65(4):353-91 contd. PMID: 4870319

Prognosis

Changes in hypothalamic-pituitary-adrenal axis function, immunity, and glucose during acute Plasmodium relictum infection in house sparrows (Passer domesticus).
Kelly TR, Cannon AL, Stansberry KR, Kimball MG, Lattin CR
Gen Comp Endocrinol 2024 Jan 1;345:114388. Epub 2023 Oct 4 doi: 10.1016/j.ygcen.2023.114388. PMID: 37802425
Transcriptional response of individual Hawaiian Culex quinquefasciatus mosquitoes to the avian malaria parasite Plasmodium relictum.
Ferreira FC, Videvall E, Seidl CM, Wagner NE, Kilpatrick AM, Fleischer RC, Fonseca DM
Malar J 2022 Aug 29;21(1):249. doi: 10.1186/s12936-022-04271-x. PMID: 36038897Free PMC Article
Plasmodium relictum infection in Culex quinquefasciatus (Culicidae) decreases diel flight activity but increases peak dusk flight activity.
Adams DR, Golnar AJ, Meyers JI, Slotman MA, Hamer GL
Malar J 2022 Aug 22;21(1):244. doi: 10.1186/s12936-022-04265-9. PMID: 35996189Free PMC Article
Vector movement underlies avian malaria at upper elevation in Hawaii: implications for transmission of human malaria.
Freed LA, Cann RL
Parasitol Res 2013 Nov;112(11):3887-95. Epub 2013 Aug 28 doi: 10.1007/s00436-013-3578-x. PMID: 23982310
Proteomic analysis of zygote and ookinete stages of the avian malaria parasite Plasmodium gallinaceum delineates the homologous proteomes of the lethal human malaria parasite Plasmodium falciparum.
Patra KP, Johnson JR, Cantin GT, Yates JR 3rd, Vinetz JM
Proteomics 2008 Jun;8(12):2492-9. doi: 10.1002/pmic.200700727. PMID: 18563747Free PMC Article

Clinical prediction guides

Suspected Mefloquine Toxicity in a Colony of Humboldt Penguins (Spheniscus humboldti).
Scala C, Oesterwind M, Lanot T
J Avian Med Surg 2023 Mar;36(4):400-405. doi: 10.1647/21-00054. PMID: 36935212
Transcriptional response of individual Hawaiian Culex quinquefasciatus mosquitoes to the avian malaria parasite Plasmodium relictum.
Ferreira FC, Videvall E, Seidl CM, Wagner NE, Kilpatrick AM, Fleischer RC, Fonseca DM
Malar J 2022 Aug 29;21(1):249. doi: 10.1186/s12936-022-04271-x. PMID: 36038897Free PMC Article
Great-tailed Grackles (Quiscalus mexicanus) as a tolerant host of avian malaria parasites.
Pacheco MA, Ferreira FC, Logan CJ, McCune KB, MacPherson MP, Albino Miranda S, Santiago-Alarcon D, Escalante AA
PLoS One 2022;17(8):e0268161. Epub 2022 Aug 23 doi: 10.1371/journal.pone.0268161. PMID: 35998118Free PMC Article
Plasmodium relictum infection in Culex quinquefasciatus (Culicidae) decreases diel flight activity but increases peak dusk flight activity.
Adams DR, Golnar AJ, Meyers JI, Slotman MA, Hamer GL
Malar J 2022 Aug 22;21(1):244. doi: 10.1186/s12936-022-04265-9. PMID: 35996189Free PMC Article
Vector movement underlies avian malaria at upper elevation in Hawaii: implications for transmission of human malaria.
Freed LA, Cann RL
Parasitol Res 2013 Nov;112(11):3887-95. Epub 2013 Aug 28 doi: 10.1007/s00436-013-3578-x. PMID: 23982310

Recent systematic reviews

Infecting dose and severity of malaria: a literature review of induced malaria.
Glynn JR
J Trop Med Hyg 1994 Oct;97(5):300-16. PMID: 7932927

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