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Melasma

MedGen UID:
7521
Concept ID:
C0025218
Disease or Syndrome
Synonyms: Chloasma; Chloasmas; Melasmas
SNOMED CT: Chloasma (36209000); Melasma (36209000)
 
HPO: HP:0025272

Definition

Symmetrical, blotchy, brownish facial pigmentation. [from HPO]

Professional guidelines

PubMed

Thawabteh AM, Jibreen A, Karaman D, Thawabteh A, Karaman R
Molecules 2023 Jun 18;28(12) doi: 10.3390/molecules28124839. PMID: 37375394Free PMC Article
Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Plensdorf S, Livieratos M, Dada N
Am Fam Physician 2017 Dec 15;96(12):797-804. PMID: 29431372

Recent clinical studies

Etiology

Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Artzi O, Horovitz T, Bar-Ilan E, Shehadeh W, Koren A, Zusmanovitch L, Mehrabi JN, Salameh F, Isman Nelkenbaum G, Zur E, Sprecher E, Mashiah J
J Cosmet Dermatol 2021 Nov;20(11):3432-3445. Epub 2021 Aug 19 doi: 10.1111/jocd.14382. PMID: 34411403
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Bala HR, Lee S, Wong C, Pandya AG, Rodrigues M
Dermatol Surg 2018 Jun;44(6):814-825. doi: 10.1097/DSS.0000000000001518. PMID: 29677015
Handel AC, Miot LD, Miot HA
An Bras Dermatol 2014 Sep-Oct;89(5):771-82. doi: 10.1590/abd1806-4841.20143063. PMID: 25184917Free PMC Article

Diagnosis

Doolan BJ, Gupta M
Aust J Gen Pract 2021 Dec;50(12):880-885. doi: 10.31128/AJGP-05-21-6002. PMID: 34845463
Searle T, Al-Niaimi F, Ali FR
Dermatol Ther 2020 Nov;33(6):e14095. Epub 2020 Sep 4 doi: 10.1111/dth.14095. PMID: 32720446
Plensdorf S, Livieratos M, Dada N
Am Fam Physician 2017 Dec 15;96(12):797-804. PMID: 29431372
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042
Ference JD, Last AR
Am Fam Physician 2009 Jan 15;79(2):135-40. PMID: 19178066

Therapy

Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Babbush KM, Babbush RA, Khachemoune A
J Drugs Dermatol 2020 Aug 1;19(8):788-792. doi: 10.36849/JDD.2020.5079. PMID: 32845595
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Kwon SH, Na JI, Choi JY, Park KC
Exp Dermatol 2019 Jun;28(6):704-708. Epub 2018 Dec 21 doi: 10.1111/exd.13844. PMID: 30422338
Bala HR, Lee S, Wong C, Pandya AG, Rodrigues M
Dermatol Surg 2018 Jun;44(6):814-825. doi: 10.1097/DSS.0000000000001518. PMID: 29677015

Prognosis

Buzalaf MAR, Levy FM
J Appl Oral Sci 2022;30:e20220020. Epub 2022 Sep 5 doi: 10.1590/1678-7757-2022-0020. PMID: 36074433Free PMC Article
de Abreu L, Ramos-E-Silva M, Quintella LP, Buçard AM, Bravo BSF, de Almeida AM, Moreira ACMS
J Cosmet Dermatol 2022 Nov;21(11):5887-5894. Epub 2022 Jun 26 doi: 10.1111/jocd.15145. PMID: 35673946
Cassiano DP, Espósito ACC, Hassun KM, Lima MMDA, Lima EVA, Miot LDB, Miot HA, Bagatin E
Indian J Dermatol Venereol Leprol 2022 Nov-Dec;88(6):761-770. doi: 10.25259/IJDVL_126_2021. PMID: 35389028
Shimshak SJE, Tolaymat LM, Haga CB, Dawson NL, Gillis MS, Yin M, Kirsch B, Cooper M, Sluzevich JC
J Cutan Med Surg 2022 Mar-Apr;26(2):169-175. Epub 2021 Sep 19 doi: 10.1177/12034754211045391. PMID: 34541912
Chatterjee M, Neema S
Dermatol Clin 2018 Oct;36(4):473-485. doi: 10.1016/j.det.2018.05.014. PMID: 30201156

Clinical prediction guides

Buzalaf MAR, Levy FM
J Appl Oral Sci 2022;30:e20220020. Epub 2022 Sep 5 doi: 10.1590/1678-7757-2022-0020. PMID: 36074433Free PMC Article
Lai D, Zhou S, Cheng S, Liu H, Cui Y
Lasers Med Sci 2022 Jun;37(4):2099-2110. Epub 2022 Feb 5 doi: 10.1007/s10103-022-03514-2. PMID: 35122202
Artzi O, Horovitz T, Bar-Ilan E, Shehadeh W, Koren A, Zusmanovitch L, Mehrabi JN, Salameh F, Isman Nelkenbaum G, Zur E, Sprecher E, Mashiah J
J Cosmet Dermatol 2021 Nov;20(11):3432-3445. Epub 2021 Aug 19 doi: 10.1111/jocd.14382. PMID: 34411403
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042
Kwon SH, Hwang YJ, Lee SK, Park KC
Int J Mol Sci 2016 May 26;17(6) doi: 10.3390/ijms17060824. PMID: 27240341Free PMC Article

Recent systematic reviews

Lee YS, Lee YJ, Lee JM, Han TY, Lee JH, Choi JE
Medicina (Kaunas) 2022 Jul 14;58(7) doi: 10.3390/medicina58070936. PMID: 35888655Free PMC Article
Lai D, Zhou S, Cheng S, Liu H, Cui Y
Lasers Med Sci 2022 Jun;37(4):2099-2110. Epub 2022 Feb 5 doi: 10.1007/s10103-022-03514-2. PMID: 35122202
Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042

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