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Melasma

MedGen UID:
7521
Concept ID:
C0025218
Disease or Syndrome
Synonyms: Chloasma; Chloasmas; Melasmas
SNOMED CT: Chloasma (36209000); Melasma (36209000)
 
HPO: HP:0025272

Definition

Symmetrical, blotchy, brownish facial pigmentation. [from HPO]

Professional guidelines

PubMed

Thawabteh AM, Jibreen A, Karaman D, Thawabteh A, Karaman R
Molecules 2023 Jun 18;28(12) doi: 10.3390/molecules28124839. PMID: 37375394Free PMC Article
Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Artzi O, Horovitz T, Bar-Ilan E, Shehadeh W, Koren A, Zusmanovitch L, Mehrabi JN, Salameh F, Isman Nelkenbaum G, Zur E, Sprecher E, Mashiah J
J Cosmet Dermatol 2021 Nov;20(11):3432-3445. Epub 2021 Aug 19 doi: 10.1111/jocd.14382. PMID: 34411403

Recent clinical studies

Etiology

Konisky H, Balazic E, Jaller JA, Khanna U, Kobets K
J Cosmet Dermatol 2023 Apr;22(4):1197-1206. Epub 2023 Jan 6 doi: 10.1111/jocd.15589. PMID: 36606378
Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Artzi O, Horovitz T, Bar-Ilan E, Shehadeh W, Koren A, Zusmanovitch L, Mehrabi JN, Salameh F, Isman Nelkenbaum G, Zur E, Sprecher E, Mashiah J
J Cosmet Dermatol 2021 Nov;20(11):3432-3445. Epub 2021 Aug 19 doi: 10.1111/jocd.14382. PMID: 34411403
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Bala HR, Lee S, Wong C, Pandya AG, Rodrigues M
Dermatol Surg 2018 Jun;44(6):814-825. doi: 10.1097/DSS.0000000000001518. PMID: 29677015

Diagnosis

Wang RF, Ko D, Friedman BJ, Lim HW, Mohammad TF
J Am Acad Dermatol 2023 Feb;88(2):271-288. Epub 2022 Feb 11 doi: 10.1016/j.jaad.2022.01.051. PMID: 35151757
Doolan BJ, Gupta M
Aust J Gen Pract 2021 Dec;50(12):880-885. doi: 10.31128/AJGP-05-21-6002. PMID: 34845463
Searle T, Al-Niaimi F, Ali FR
Dermatol Ther 2020 Nov;33(6):e14095. Epub 2020 Sep 4 doi: 10.1111/dth.14095. PMID: 32720446
Plensdorf S, Livieratos M, Dada N
Am Fam Physician 2017 Dec 15;96(12):797-804. PMID: 29431372
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042

Therapy

Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
Babbush KM, Babbush RA, Khachemoune A
J Drugs Dermatol 2020 Aug 1;19(8):788-792. doi: 10.36849/JDD.2020.5079. PMID: 32845595
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Kwon SH, Na JI, Choi JY, Park KC
Exp Dermatol 2019 Jun;28(6):704-708. Epub 2018 Dec 21 doi: 10.1111/exd.13844. PMID: 30422338
Bala HR, Lee S, Wong C, Pandya AG, Rodrigues M
Dermatol Surg 2018 Jun;44(6):814-825. doi: 10.1097/DSS.0000000000001518. PMID: 29677015

Prognosis

Guida S, Longo C, Ronga R, Stabile G, Podo Brunetti A, Bigotto GD, Conforti C, Ciardo S, Cantisani C, Paolino G, Mercuri SR, Nisticò SP, Zerbinati N, Rongioletti F, Pellacani G
Int J Dermatol 2024 Aug;63(8):1007-1012. Epub 2024 Mar 6 doi: 10.1111/ijd.17117. PMID: 38448367
Buzalaf MAR, Levy FM
J Appl Oral Sci 2022;30:e20220020. Epub 2022 Sep 5 doi: 10.1590/1678-7757-2022-0020. PMID: 36074433Free PMC Article
Cassiano DP, Espósito ACC, Hassun KM, Lima MMDA, Lima EVA, Miot LDB, Miot HA, Bagatin E
Indian J Dermatol Venereol Leprol 2022 Nov-Dec;88(6):761-770. doi: 10.25259/IJDVL_126_2021. PMID: 35389028
Chatterjee M, Neema S
Dermatol Clin 2018 Oct;36(4):473-485. doi: 10.1016/j.det.2018.05.014. PMID: 30201156
Lee CS, Lim HW
Dermatol Clin 2003 Oct;21(4):669-77. doi: 10.1016/s0733-8635(03)00078-0. PMID: 14717407

Clinical prediction guides

Konisky H, Balazic E, Jaller JA, Khanna U, Kobets K
J Cosmet Dermatol 2023 Apr;22(4):1197-1206. Epub 2023 Jan 6 doi: 10.1111/jocd.15589. PMID: 36606378
Pixley JN, Cook MK, Singh R, Larrondo J, McMichael AJ
J Dermatolog Treat 2023 Dec;34(1):2142035. doi: 10.1080/09546634.2022.2142035. PMID: 36318219
Buzalaf MAR, Levy FM
J Appl Oral Sci 2022;30:e20220020. Epub 2022 Sep 5 doi: 10.1590/1678-7757-2022-0020. PMID: 36074433Free PMC Article
Artzi O, Horovitz T, Bar-Ilan E, Shehadeh W, Koren A, Zusmanovitch L, Mehrabi JN, Salameh F, Isman Nelkenbaum G, Zur E, Sprecher E, Mashiah J
J Cosmet Dermatol 2021 Nov;20(11):3432-3445. Epub 2021 Aug 19 doi: 10.1111/jocd.14382. PMID: 34411403
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042

Recent systematic reviews

Lee YS, Lee YJ, Lee JM, Han TY, Lee JH, Choi JE
Medicina (Kaunas) 2022 Jul 14;58(7) doi: 10.3390/medicina58070936. PMID: 35888655Free PMC Article
Lai D, Zhou S, Cheng S, Liu H, Cui Y
Lasers Med Sci 2022 Jun;37(4):2099-2110. Epub 2022 Feb 5 doi: 10.1007/s10103-022-03514-2. PMID: 35122202
Neagu N, Conforti C, Agozzino M, Marangi GF, Morariu SH, Pellacani G, Persichetti P, Piccolo D, Segreto F, Zalaudek I, Dianzani C
J Dermatolog Treat 2022 Jun;33(4):1816-1837. Epub 2022 Mar 23 doi: 10.1080/09546634.2021.1914313. PMID: 33849384
McKesey J, Tovar-Garza A, Pandya AG
Am J Clin Dermatol 2020 Apr;21(2):173-225. doi: 10.1007/s40257-019-00488-w. PMID: 31802394
Kim HJ, Moon SH, Cho SH, Lee JD, Kim HS
Acta Derm Venereol 2017 Jul 6;97(7):776-781. doi: 10.2340/00015555-2668. PMID: 28374042

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