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Becker Nevus(PCZH)

MedGen UID:
75526
Concept ID:
C0263579
Disease or Syndrome
Synonyms: BECKER NEVUS; HYPERPIGMENTATION, PROGRESSIVE CRIBRIFORM AND ZOSTERIFORM; PCZH
SNOMED CT: Pigmented hairy epidermal nevus (5387003); Becker's nevus (5387003); Pigmented hairy nevus of Becker (5387003); PCZH - progressive cribriform and zosteriform hyperpigmentation (878889000); Progressive cribriform and zosteriform hyperpigmentation (878889000)
 
OMIM®: 102630; 604919; 614323

Definition

A benign lesion that is sometimes congenital and consists of an overgrowth of the epidermis and the presence of melanin-containing cells. It is found mostly in males and typically develops during childhood or adolescence, becoming darker and more hairy after puberty. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBecker Nevus

Professional guidelines

PubMed

Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675
Alkhalifah A, Fransen F, Le Duff F, Lacour JP, Wolkerstorfer A, Passeron T
J Am Acad Dermatol 2020 Dec;83(6):1606-1615. Epub 2019 Jun 13 doi: 10.1016/j.jaad.2019.06.013. PMID: 31202870
Carpo BG, Grevelink JM, Grevelink SV
Semin Cutan Med Surg 1999 Sep;18(3):233-43. doi: 10.1016/s1085-5629(99)80021-2. PMID: 10468043

Recent clinical studies

Etiology

Wu PR, Liu LJ, Zhang YX, Liu Y, Lin XX, Ma G
J Dermatolog Treat 2021 May;32(3):334-339. Epub 2019 Sep 2 doi: 10.1080/09546634.2019.1656795. PMID: 31416363
Zhong Y, Yang B, Huang L, Elias PM, Man MQ
Lasers Med Sci 2019 Aug;34(6):1071-1079. Epub 2019 Feb 14 doi: 10.1007/s10103-019-02734-3. PMID: 30762191Free PMC Article
Passeron T
Ann Dermatol Venereol 2012 Dec;139 Suppl 4:S159-65. doi: 10.1016/S0151-9638(12)70129-1. PMID: 23522632
Happle R
J Am Acad Dermatol 2010 Jul;63(1):1-22; quiz 23-4. doi: 10.1016/j.jaad.2010.01.017. PMID: 20542174
Ro YS, Ko JY
Cutis 2005 Feb;75(2):122-4. PMID: 15773534

Diagnosis

Bhattacharjee R, Vinay K
Breast J 2019 Nov;25(6):1294. Epub 2019 Jul 12 doi: 10.1111/tbj.13459. PMID: 31297897
Patel P, Malik K, Khachemoune A
Am J Clin Dermatol 2015 Jun;16(3):197-204. doi: 10.1007/s40257-015-0123-y. PMID: 25782676
Passeron T
Ann Dermatol Venereol 2012 Dec;139 Suppl 4:S159-65. doi: 10.1016/S0151-9638(12)70129-1. PMID: 23522632
Sugarman JL
Semin Cutan Med Surg 2007 Dec;26(4):221-30. doi: 10.1016/j.sder.2008.03.006. PMID: 18395670
Sugarman JL
Semin Cutan Med Surg 2004 Jun;23(2):145-57. doi: 10.1016/j.sder.2004.01.008. PMID: 15295924

Therapy

Wu PR, Liu LJ, Zhang YX, Liu Y, Lin XX, Ma G
J Dermatolog Treat 2021 May;32(3):334-339. Epub 2019 Sep 2 doi: 10.1080/09546634.2019.1656795. PMID: 31416363
Alkhalifah A, Fransen F, Le Duff F, Lacour JP, Wolkerstorfer A, Passeron T
J Am Acad Dermatol 2020 Dec;83(6):1606-1615. Epub 2019 Jun 13 doi: 10.1016/j.jaad.2019.06.013. PMID: 31202870
Zhong Y, Chen Y, Huang L, Wang H, Yan T, Yang B, Man MQ
J Am Acad Dermatol 2019 Jan;80(1):e3. Epub 2018 Jul 24 doi: 10.1016/j.jaad.2018.07.016. PMID: 30048662
Momen S, Mallipeddi R, Al-Niaimi F
J Cosmet Laser Ther 2016 Aug;18(4):188-92. Epub 2016 Mar 11 doi: 10.3109/14764172.2015.1114647. PMID: 26735085
Meesters AA, Wind BS, Kroon MW, Wolkerstorfer A, van der Veen JP, Nieuweboer-Krobotová L, van der Wal AC, Bos JD, Beek JF
J Am Acad Dermatol 2011 Dec;65(6):1173-9. doi: 10.1016/j.jaad.2010.07.049. PMID: 21641077

Prognosis

Alkhalifah A, Fransen F, Le Duff F, Lacour JP, Wolkerstorfer A, Passeron T
J Am Acad Dermatol 2020 Dec;83(6):1606-1615. Epub 2019 Jun 13 doi: 10.1016/j.jaad.2019.06.013. PMID: 31202870
Patrizi A, Medri M, Raone B, Bianchi F, Aprile S, Neri I
Pediatr Dermatol 2012 Sep-Oct;29(5):571-4. Epub 2012 Apr 4 doi: 10.1111/j.1525-1470.2012.01734.x. PMID: 22471889
Alhusayen R, Kanigsberg N, Jackson R
J Cutan Med Surg 2008 Jan-Feb;12(1):31-4. doi: 10.2310/7750.2007.00034. PMID: 18258146
Ro YS, Ko JY
Cutis 2005 Feb;75(2):122-4. PMID: 15773534
Al Aboud K, Al Hawsawi K
Eur J Dermatol 2002 Nov-Dec;12(6):588. PMID: 12506884

Clinical prediction guides

Wu PR, Liu LJ, Zhang YX, Liu Y, Lin XX, Ma G
J Dermatolog Treat 2021 May;32(3):334-339. Epub 2019 Sep 2 doi: 10.1080/09546634.2019.1656795. PMID: 31416363
Passeron T
Ann Dermatol Venereol 2012 Dec;139 Suppl 4:S159-65. doi: 10.1016/S0151-9638(12)70129-1. PMID: 23522632
Meesters AA, Wind BS, Kroon MW, Wolkerstorfer A, van der Veen JP, Nieuweboer-Krobotová L, van der Wal AC, Bos JD, Beek JF
J Am Acad Dermatol 2011 Dec;65(6):1173-9. doi: 10.1016/j.jaad.2010.07.049. PMID: 21641077
Sciallis GF, Sciallis AP
Arch Dermatol 2010 Dec;146(12):1408-12. doi: 10.1001/archdermatol.2010.369. PMID: 21173323
Ingordo V, Iannazzone SS, Cusano F, Naldi L
Dermatology 2006;212(4):354-60. doi: 10.1159/000092286. PMID: 16707885

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