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Double kidney

MedGen UID:
75608
•Concept ID:
C0266304
•
Congenital Abnormality
Synonyms: Duplex kidney; Duplex kidneys
SNOMED CT: Double kidney (54967001); Duplex kidney (54967001)

Definition

A congenital abnormality of the kidney characterized by the presence of two separate pelvicocaliceal systems with a single or duplex ureter. [from NCI]

Professional guidelines

PubMed

Expanded Criteria Donor Kidney Transplantation: Comparative Outcome Evaluation Between Single Versus Double Kidney Transplantation at 8 Years: A Single Center Experience.
De Paolis P, Colonnelli R, Favarò A, Salem F, Vignally P, Carriero C, Iappelli M, Di Giulio S
Transplant Proc 2016 Mar;48(2):329-32. doi: 10.1016/j.transproceed.2016.02.007. PMID: 27109948
Extended criteria donor kidney transplantation: comparative outcome analysis between single versus double kidney transplantation at 5 years.
Lucarelli G, Bettocchi C, Battaglia M, Impedovo SV, Vavallo A, Grandaliano G, Castellano G, Schena FP, Selvaggi FP, Ditonno P
Transplant Proc 2010 May;42(4):1104-7. doi: 10.1016/j.transproceed.2010.03.059. PMID: 20534234
Early experience with dual kidney transplantation in adults using expanded donor criteria. Double Kidney Transplant Group (DKG).
Remuzzi G, Grinyò J, Ruggenenti P, Beatini M, Cole EH, Milford EL, Brenner BM
J Am Soc Nephrol 1999 Dec;10(12):2591-8. doi: 10.1681/ASN.V10122591. PMID: 10589699

Recent clinical studies

Etiology

Radical cystectomy and urinary diversion outcomes in patients with single vs. double renal unit: A 2:1 matched-pair analysis.
Mora RM, Ghoreifi A, Ladi-Seyedian SS, Sheybaee Moghaddam F, Cai J, Miranda G, Aron M, Schuckman A, Desai M, Gill I, Daneshmand S, Djaladat H
Urol Oncol 2023 Apr;41(4):207.e17-207.e22. Epub 2022 Dec 22 doi: 10.1016/j.urolonc.2022.12.004. PMID: 36566106
Assessment of donor biopsies.
Hopfer H, Kemény É
Curr Opin Organ Transplant 2013 Jun;18(3):306-12. doi: 10.1097/MOT.0b013e3283607a6e. PMID: 23492644
Diabetes cell therapy: a decade later.
Vantyghem MC, Balavoine AS, Caiazzo R, Kerr-Conte J, Noel C, Pattou F
Minerva Endocrinol 2011 Mar;36(1):23-39. PMID: 21460785
Who should benefit from diabetes cell therapy?
Vantyghem MC, Balavoine AS, Kerr-Conte J, Pattou F, Noel C
Ann Endocrinol (Paris) 2009 Dec;70(6):443-8. Epub 2009 Sep 9 doi: 10.1016/j.ando.2009.08.002. PMID: 19744642
Double kidney transplant.
Riera L, Serón D, Franco E, Suárez JF, Fulladosa X, Ramos R, Gil-Vernet S, Condóm E, González C, Grinyó JM, Serrallach N
Transplant Proc 1999 Sep;31(6):2287-9. doi: 10.1016/s0041-1345(99)00342-5. PMID: 10500581

Diagnosis

Hypothermic Machine Perfusion as an Alternative to Biopsy Assessment in Transplantation of Kidneys Donated After Cardiocirculatory Death: A Pilot Study.
Bissolati M, Pindozzi F, Guarneri G, Adamenko O, Giannone F, Mazza M, Maggi G, Rosati R, Secchi A, Socci C
Transplant Proc 2019 Nov;51(9):2890-2898. Epub 2019 Oct 9 doi: 10.1016/j.transproceed.2019.02.069. PMID: 31606185
Organs from deceased donors with false-positive HIV screening tests: An unexpected benefit of the HOPE act.
Durand CM, Halpern SE, Bowring MG, Bismut GA, Kusemiju OT, Doby B, Fernandez RE, Kirby CS, Ostrander D, Stock PG, Mehta S, Turgeon NA, Wojciechowski D, Huprikar S, Florman S, Ottmann S, Desai NM, Cameron A, Massie AB, Tobian AAR, Redd AD, Segev DL
Am J Transplant 2018 Oct;18(10):2579-2586. Epub 2018 Jul 23 doi: 10.1111/ajt.14993. PMID: 29947471Free PMC Article
Ultrasonographic findings in dual kidney transplantation.
Impedovo SV, Martino P, Palazzo S, Ditonno P, Tedeschi M, Palumbo F, Tafa A, Matera M, Selvaggi FP, Battaglia M
Arch Ital Urol Androl 2012 Dec;84(4):245-8. PMID: 23427755
New normal values not related to age and sex, of glomerular filtration rate by (99m)Tc-DTPA renal dynamic imaging, for the evaluation of living kidney graft donors.
Zhao X, Shao Y, Wang Y, Tian J, Sun B, Ru Y, Zhang A, Hao J
Hell J Nucl Med 2012 Sep-Dec;15(3):210-4. Epub 2012 Oct 25 doi: 10.1967/s002449910057. PMID: 23106053
Embryonal teratoma in double kidney.
Hamvasi G, Kottász S, Fürst F, Veress B
Acta Chir Acad Sci Hung 1971;12(2):175-9. PMID: 4329263

Therapy

Risk Factors and Rates of Occurrence of Ureteral Stricture Formation Following Renal Transplantation: A Literature Review.
Patel S, Denis T, Gaba F, Inouye B, White M, Yamamoto T, Shahbazov R
Exp Clin Transplant 2024 Sep;22(9):655-663. doi: 10.6002/ect.2024.0191. PMID: 39431832
Safety evaluations of offspring breastfed by mothers receiving glatiramer acetate for relapsing multiple sclerosis.
Ciplea AI, Kurzeja A, Thiel S, Haben S, Adamus E, Hellwig K
Mult Scler Relat Disord 2023 Jul;75:104771. Epub 2023 May 22 doi: 10.1016/j.msard.2023.104771. PMID: 37245349
Diabetes cell therapy: a decade later.
Vantyghem MC, Balavoine AS, Caiazzo R, Kerr-Conte J, Noel C, Pattou F
Minerva Endocrinol 2011 Mar;36(1):23-39. PMID: 21460785
Who should benefit from diabetes cell therapy?
Vantyghem MC, Balavoine AS, Kerr-Conte J, Pattou F, Noel C
Ann Endocrinol (Paris) 2009 Dec;70(6):443-8. Epub 2009 Sep 9 doi: 10.1016/j.ando.2009.08.002. PMID: 19744642
Ipsilateral placement in double-kidney transplantation.
Gaber AO, Shokouh-Amiri H, Nezakatgoo N, Gaber LW, Saharia A, Shimizu A, Mehrazin R, Moore LW
Transplantation 2007 Oct 15;84(7):929-31. doi: 10.1097/01.tp.0000281537.15427.93. PMID: 17984848

Prognosis

Risk Factors and Rates of Occurrence of Ureteral Stricture Formation Following Renal Transplantation: A Literature Review.
Patel S, Denis T, Gaba F, Inouye B, White M, Yamamoto T, Shahbazov R
Exp Clin Transplant 2024 Sep;22(9):655-663. doi: 10.6002/ect.2024.0191. PMID: 39431832
Assessment of donor biopsies.
Hopfer H, Kemény É
Curr Opin Organ Transplant 2013 Jun;18(3):306-12. doi: 10.1097/MOT.0b013e3283607a6e. PMID: 23492644
Diabetes cell therapy: a decade later.
Vantyghem MC, Balavoine AS, Caiazzo R, Kerr-Conte J, Noel C, Pattou F
Minerva Endocrinol 2011 Mar;36(1):23-39. PMID: 21460785
Utilization of suboptimal kidney donors.
Faenza A, Sestigliani E, Zambianchi L, Ridolfi L
Transplant Proc 2004 Apr;36(3):485-7. doi: 10.1016/j.transproceed.2004.03.070. PMID: 15110565
Double kidney transplant.
Riera L, Serón D, Franco E, Suárez JF, Fulladosa X, Ramos R, Gil-Vernet S, Condóm E, González C, Grinyó JM, Serrallach N
Transplant Proc 1999 Sep;31(6):2287-9. doi: 10.1016/s0041-1345(99)00342-5. PMID: 10500581

Clinical prediction guides

Expanded Criteria Donor Kidney Transplantation: Comparative Outcome Evaluation Between Single Versus Double Kidney Transplantation at 8 Years: A Single Center Experience.
De Paolis P, Colonnelli R, Favarò A, Salem F, Vignally P, Carriero C, Iappelli M, Di Giulio S
Transplant Proc 2016 Mar;48(2):329-32. doi: 10.1016/j.transproceed.2016.02.007. PMID: 27109948
Assessment of donor biopsies.
Hopfer H, Kemény É
Curr Opin Organ Transplant 2013 Jun;18(3):306-12. doi: 10.1097/MOT.0b013e3283607a6e. PMID: 23492644
Single-center experience in double kidney transplantation.
Fontana I, Magoni Rossi A, Gasloli G, Santori G, Giannone A, Bertocchi M, Piaggio F, Bocci E, Valente U
Transplant Proc 2010 May;42(4):1108-10. doi: 10.1016/j.transproceed.2010.03.063. PMID: 20534235
Application and validation of Cox regression models in a single-center series of double kidney transplantation.
Santori G, Fontana I, Bertocchi M, Gasloli G, Magoni Rossi A, Tagliamacco A, Barocci S, Nocera A, Valente U
Transplant Proc 2010 May;42(4):1098-103. doi: 10.1016/j.transproceed.2010.03.037. PMID: 20534233
Who should benefit from diabetes cell therapy?
Vantyghem MC, Balavoine AS, Kerr-Conte J, Pattou F, Noel C
Ann Endocrinol (Paris) 2009 Dec;70(6):443-8. Epub 2009 Sep 9 doi: 10.1016/j.ando.2009.08.002. PMID: 19744642

Recent systematic reviews

Risk Factors and Rates of Occurrence of Ureteral Stricture Formation Following Renal Transplantation: A Literature Review.
Patel S, Denis T, Gaba F, Inouye B, White M, Yamamoto T, Shahbazov R
Exp Clin Transplant 2024 Sep;22(9):655-663. doi: 10.6002/ect.2024.0191. PMID: 39431832

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