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Vesicular stomatitis

MedGen UID:
75624
•Concept ID:
C0266999
•
Disease or Syndrome
Synonyms: Stomatitides, Vesicular; Stomatitis, Vesicular; Vesicular Stomatitides; Vesicular Stomatitis
SNOMED CT: Vesicular stomatitis (36921006)

Definition

A viral disease caused by at least two distinct species (serotypes) in the VESICULOVIRUS genus: VESICULAR STOMATITIS INDIANA VIRUS and VESICULAR STOMATITIS NEW JERSEY VIRUS. It is characterized by vesicular eruptions on the ORAL MUCOSA in cattle, horses, pigs, and other animals. In humans, vesicular stomatitis causes an acute influenza-like illness. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVesicular stomatitis

Professional guidelines

PubMed

Recent advances in the treatment of Ebola disease: A brief overview.
El Ayoubi LW, Mahmoud O, Zakhour J, Kanj SS
PLoS Pathog 2024 Mar;20(3):e1012038. Epub 2024 Mar 15 doi: 10.1371/journal.ppat.1012038. PMID: 38489257Free PMC Article
Efficient Delivery and Replication of Oncolytic Virus for Successful Treatment of Head and Neck Cancer.
Hamada M, Yura Y
Int J Mol Sci 2020 Sep 25;21(19) doi: 10.3390/ijms21197073. PMID: 32992948Free PMC Article
Potential and emerging treatment options for Ebola virus disease.
Bishop BM
Ann Pharmacother 2015 Feb;49(2):196-206. Epub 2014 Nov 20 doi: 10.1177/1060028014561227. PMID: 25414384

Recent clinical studies

Etiology

Transcriptional profiling of immune responses in NHPs after low-dose, VSV-based vaccination against Marburg virus.
Prator CA, Dorratt BM, O'Donnell KL, Lack J, Pinski AN, Ricklefs S, Martens CA, Messaoudi I, Marzi A
Emerg Microbes Infect 2023 Dec;12(2):2252513. doi: 10.1080/22221751.2023.2252513. PMID: 37616377Free PMC Article
The role of sand flies as vectors of viruses other than phleboviruses.
Jancarova M, Polanska N, Volf P, Dvorak V
J Gen Virol 2023 Apr;104(4) doi: 10.1099/jgv.0.001837. PMID: 37018120
The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis.
Erttmann SF, Swacha P, Aung KM, Brindefalk B, Jiang H, Härtlova A, Uhlin BE, Wai SN, Gekara NO
Immunity 2022 May 10;55(5):847-861.e10. doi: 10.1016/j.immuni.2022.04.006. PMID: 35545033
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Xiao J, Li W, Zheng X, Qi L, Wang H, Zhang C, Wan X, Zheng Y, Zhong R, Zhou X, Lu Y, Li Z, Qiu Y, Liu C, Zhang F, Zhang Y, Xu X, Yang Z, Chen H, Zhai Q, Wei B, Wang H
Immunity 2020 Jan 14;52(1):109-122.e6. Epub 2019 Dec 24 doi: 10.1016/j.immuni.2019.11.015. PMID: 31882361
Gene therapy for PIDs: progress, pitfalls and prospects.
Mukherjee S, Thrasher AJ
Gene 2013 Aug 10;525(2):174-81. Epub 2013 Apr 6 doi: 10.1016/j.gene.2013.03.098. PMID: 23566838Free PMC Article

Diagnosis

MARCH8 inhibits viral infection by two different mechanisms.
Zhang Y, Tada T, Ozono S, Kishigami S, Fujita H, Tokunaga K
Elife 2020 Aug 11;9 doi: 10.7554/eLife.57763. PMID: 32778221Free PMC Article
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Zhu Q, Yu T, Gan S, Wang Y, Pei Y, Zhao Q, Pei S, Hao S, Yuan J, Xu J, Hou F, Wu X, Peng C, Wu P, Qin J, Xiao Y
J Exp Med 2020 Jul 6;217(7) doi: 10.1084/jem.20192083. PMID: 32324863Free PMC Article
Direct trafficking pathways from the Golgi apparatus to the plasma membrane.
Stalder D, Gershlick DC
Semin Cell Dev Biol 2020 Nov;107:112-125. Epub 2020 Apr 13 doi: 10.1016/j.semcdb.2020.04.001. PMID: 32317144Free PMC Article
Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2.
Nie J, Li Q, Wu J, Zhao C, Hao H, Liu H, Zhang L, Nie L, Qin H, Wang M, Lu Q, Li X, Sun Q, Liu J, Fan C, Huang W, Xu M, Wang Y
Emerg Microbes Infect 2020 Dec;9(1):680-686. doi: 10.1080/22221751.2020.1743767. PMID: 32207377Free PMC Article
Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses.
Carocci M, Yang PL
Antiviral Res 2016 Apr;128:57-62. Epub 2016 Feb 10 doi: 10.1016/j.antiviral.2016.02.005. PMID: 26872864Free PMC Article

Therapy

Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles.
Zickler AM, Liang X, Gupta D, Mamand DR, De Luca M, Corso G, Errichelli L, Hean J, Sen T, Elsharkasy OM, Kamei N, Niu Z, Zhou G, Zhou H, Roudi S, Wiklander OPB, Görgens A, Nordin JZ, Castilla-Llorente V, El Andaloussi S
Adv Sci (Weinh) 2024 Nov;11(42):e2407619. Epub 2024 Sep 9 doi: 10.1002/advs.202407619. PMID: 39246205Free PMC Article
Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy.
Taha Z, Crupi MJF, Alluqmani N, MacKenzie D, Vallati S, Whelan JT, Fareez F, Alwithenani A, Petryk J, Chen A, Spinelli MM, Ng K, Sobh J, de Souza CT, Bharadwa PR, Lee TKH, Thomas DA, Huang BZ, Kassas O, Poutou J, Gilchrist VH, Boulton S, Thomson M, Marius R, Hooshyar M, McComb S, Arulanandam R, Ilkow CS, Bell JC, Diallo JS
Nat Commun 2024 Aug 23;15(1):7267. doi: 10.1038/s41467-024-51498-0. PMID: 39179564Free PMC Article
Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases.
Wang S, Liang B, Wang W, Li L, Feng N, Zhao Y, Wang T, Yan F, Yang S, Xia X
Signal Transduct Target Ther 2023 Apr 7;8(1):149. doi: 10.1038/s41392-023-01408-5. PMID: 37029123Free PMC Article
Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG
Nat Commun 2021 Mar 26;12(1):1930. doi: 10.1038/s41467-021-22115-1. PMID: 33772027Free PMC Article
Oncolytic viruses: From bench to bedside with a focus on safety.
Buijs PR, Verhagen JH, van Eijck CH, van den Hoogen BG
Hum Vaccin Immunother 2015;11(7):1573-84. doi: 10.1080/21645515.2015.1037058. PMID: 25996182Free PMC Article

Prognosis

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG
Nat Commun 2021 Mar 26;12(1):1930. doi: 10.1038/s41467-021-22115-1. PMID: 33772027Free PMC Article
Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus-Based Vaccines.
Stein DR, Sroga P, Warner BM, Deschambault Y, Poliquin G, Safronetz D
Emerg Infect Dis 2019 Aug;25(8):1563-1566. Epub 2019 Aug 17 doi: 10.3201/eid2508.190281. PMID: 31141474Free PMC Article
Durability of single-dose rVSV-ZEBOV vaccine responses: what do we know?
Huttner A, Siegrist CA
Expert Rev Vaccines 2018 Dec;17(12):1105-1110. Epub 2018 Nov 15 doi: 10.1080/14760584.2018.1546582. PMID: 30422031
IFITM3 requires an amphipathic helix for antiviral activity.
Chesarino NM, Compton AA, McMichael TM, Kenney AD, Zhang L, Soewarna V, Davis M, Schwartz O, Yount JS
EMBO Rep 2017 Oct;18(10):1740-1751. Epub 2017 Aug 23 doi: 10.15252/embr.201744100. PMID: 28835547Free PMC Article
Traffic through the Golgi apparatus.
Pelham HR
J Cell Biol 2001 Dec 24;155(7):1099-101. doi: 10.1083/jcb.200110160. PMID: 11756463Free PMC Article

Clinical prediction guides

SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus.
Alkayyal AA, Ajina R, Cacciabue M, Alkayyal AA, Saeedi NH, Hussain Alshehry T, Kaboha F, Alotaibi MA, Zaidan N, Shah K, Alroqi F, Bakur Mahmoud A
Front Immunol 2023;14:1082191. Epub 2023 Jan 31 doi: 10.3389/fimmu.2023.1082191. PMID: 36798114Free PMC Article
Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG
Nat Commun 2021 Mar 26;12(1):1930. doi: 10.1038/s41467-021-22115-1. PMID: 33772027Free PMC Article
Durability of single-dose rVSV-ZEBOV vaccine responses: what do we know?
Huttner A, Siegrist CA
Expert Rev Vaccines 2018 Dec;17(12):1105-1110. Epub 2018 Nov 15 doi: 10.1080/14760584.2018.1546582. PMID: 30422031
Dioscin's antiviral effect in vitro.
Liu C, Wang Y, Wu C, Pei R, Song J, Chen S, Chen X
Virus Res 2013 Mar;172(1-2):9-14. Epub 2012 Dec 10 doi: 10.1016/j.virusres.2012.12.001. PMID: 23238077
Traffic through the Golgi apparatus.
Pelham HR
J Cell Biol 2001 Dec 24;155(7):1099-101. doi: 10.1083/jcb.200110160. PMID: 11756463Free PMC Article

Recent systematic reviews

Filtering Facepiece Respirator (N95 Respirator) Reprocessing: A Systematic Review.
Schumm MA, Hadaya JE, Mody N, Myers BA, Maggard-Gibbons M
JAMA 2021 Apr 6;325(13):1296-1317. doi: 10.1001/jama.2021.2531. PMID: 33656543
Systematic review of Marburg virus vaccine nonhuman primate studies and human clinical trials.
Dulin N, Spanier A, Merino K, Hutter JN, Waterman PE, Lee C, Hamer MJ
Vaccine 2021 Jan 8;39(2):202-208. Epub 2020 Dec 9 doi: 10.1016/j.vaccine.2020.11.042. PMID: 33309082
A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option.
Peterson A, Bansal A, Hofman F, Chen TC, Zada G
J Neurooncol 2014 Feb;116(3):437-46. Epub 2014 Jan 8 doi: 10.1007/s11060-013-1346-5. PMID: 24398618
Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: a review.
Peng W, Qin R, Li X, Zhou H
J Ethnopharmacol 2013 Jul 30;148(3):729-45. Epub 2013 May 22 doi: 10.1016/j.jep.2013.05.007. PMID: 23707210

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