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Hyperproteinemia

MedGen UID:
75648
•Concept ID:
C0267988
•
Disease or Syndrome; Finding
SNOMED CT: Hyperproteinemia (37064009)
 
HPO: HP:0002152

Definition

An increased concentration of proteins in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperproteinemia

Professional guidelines

PubMed

Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
Diagnosis, pathophysiology, and treatment of chronic twin-to-twin transfusion syndrome.
Weiner CP, Ludomirski A
Fetal Diagn Ther 1994 Sep-Oct;9(5):283-90. doi: 10.1159/000263949. PMID: 7818775

Recent clinical studies

Etiology

Associations between presence of Bartonella species deoxyribonucleic acid and complete blood cell count and serum biochemical changes in client-owned cats.
Williams M, Rao S, Braff J, Buch JS, Chandrashekar R, Lappin MR
J Vet Intern Med 2022 Mar;36(2):532-540. Epub 2022 Feb 7 doi: 10.1111/jvim.16376. PMID: 35132685Free PMC Article
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
The sand rat, Psammomys obesus, develops type 2 diabetic retinopathy similar to humans.
Saïdi T, Mbarek S, Omri S, Behar-Cohen F, Chaouacha-Chekir RB, Hicks D
Invest Ophthalmol Vis Sci 2011 Nov 21;52(12):8993-9004. doi: 10.1167/iovs.11-8423. PMID: 21989730
Pediatric visceral Leishmaniasis in Turkey.
Tanir G, Taylan Ozkan A, Dağlar E
Pediatr Int 2006 Feb;48(1):66-9. doi: 10.1111/j.1442-200X.2006.02153.x. PMID: 16490074
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010

Diagnosis

A uterine pseudotumor of immunoglobulin G4-related disease.
Senda Y, Ikeda Y, Tamauchi S, Yoshikawa N, Kikkawa F, Kajiyama H
J Obstet Gynaecol Res 2021 Jan;47(1):430-435. Epub 2020 Oct 15 doi: 10.1111/jog.14531. PMID: 33059388
Hyponatremia.
DiBartola SP
Vet Clin North Am Small Anim Pract 1998 May;28(3):515-32. doi: 10.1016/s0195-5616(98)50053-8. PMID: 9597712
Assessment of hypocalcemia and hypercalcemia.
Bourke E, Delaney V
Clin Lab Med 1993 Mar;13(1):157-81. PMID: 8462259
Pseudohyponatremia.
Aw TC, Kiechle FL
Am J Emerg Med 1985 May;3(3):236-9. doi: 10.1016/0735-6757(85)90096-8. PMID: 3994801
Gaps--anionic and osmolal.
Smithline N, Gardner KD Jr
JAMA 1976 Oct 4;236(14):1594-7. doi: 10.1001/jama.236.14.1594. PMID: 989132

Therapy

Oral supplementation with Lithothamnion extract in horses subjected to oligofructose overload intake: effects on systemic inflammation and multiple organ function.
Cota LO, Júnior OS, Oliveira APL, Paz CFR, Maróstica TP, Duarte PC, Leme FOP, Faleiros RR
J Equine Vet Sci 2022 Oct;117:104082. Epub 2022 Jul 16 doi: 10.1016/j.jevs.2022.104082. PMID: 35850436
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
Electrolytes: Sodium Disorders.
Braun MM, Mahowald M
FP Essent 2017 Aug;459:11-20. PMID: 28806046
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010

Prognosis

Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Dural plasmacytoma revealing multiple myeloma. Case report.
Haegelen C, Riffaud L, Bernard M, Carsin-Nicol B, Morandi X
J Neurosurg 2006 Apr;104(4):608-10. doi: 10.3171/jns.2006.104.4.608. PMID: 16619666
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010
Ciliary body cysts in multiple myeloma. Their relation to urethane, hyperproteinemia, and duration of the disease.
Slansky HH, Bronstein M, Gartner S
Arch Ophthalmol 1966 Nov;76(5):686-9. doi: 10.1001/archopht.1966.03850010688011. PMID: 5955153

Clinical prediction guides

Oral supplementation with Lithothamnion extract in horses subjected to oligofructose overload intake: effects on systemic inflammation and multiple organ function.
Cota LO, Júnior OS, Oliveira APL, Paz CFR, Maróstica TP, Duarte PC, Leme FOP, Faleiros RR
J Equine Vet Sci 2022 Oct;117:104082. Epub 2022 Jul 16 doi: 10.1016/j.jevs.2022.104082. PMID: 35850436
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Pediatric visceral Leishmaniasis in Turkey.
Tanir G, Taylan Ozkan A, Dağlar E
Pediatr Int 2006 Feb;48(1):66-9. doi: 10.1111/j.1442-200X.2006.02153.x. PMID: 16490074
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010

Recent systematic reviews

Gram-negative meningitis associated with transsphenoidal surgery: case reports and review.
Haile-Mariam T, Laws E, Tuazon CU
Clin Infect Dis 1994 Apr;18(4):553-6. doi: 10.1093/clinids/18.4.553. PMID: 8038309

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