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Nocturnal hypoxemia

MedGen UID:
758908
Concept ID:
C3531793
Finding
Synonyms: Sleep hypoxemia; Sleep related hypoxemia; Sleep-related hypoxemia
SNOMED CT: Sleep related hypoxemia (288581000119102)
 
HPO: HP:0034312

Definition

Abnormally reduced oxyhemoglobin saturation during sleep (nocturnal). Different thresholds are used in the literature, including more than 10 percent of total sleep time below a SpO2 of 90 percent. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNocturnal hypoxemia

Professional guidelines

PubMed

Nguyen DB, Khirani S, Griffon L, Baujat G, Michot C, Marzin P, Rondeau S, Luscan R, Couloigner V, Pejin Z, Zerah M, Cormier-Daire V, Fauroux B
Am J Med Genet A 2021 Jul;185(7):2108-2118. Epub 2021 Apr 28 doi: 10.1002/ajmg.a.62236. PMID: 33908178
Budhiraja R, Siddiqi TA, Quan SF
J Clin Sleep Med 2015 Mar 15;11(3):259-70. doi: 10.5664/jcsm.4540. PMID: 25700872Free PMC Article
Wang WC
Curr Opin Hematol 2007 May;14(3):191-7. doi: 10.1097/MOH.0b013e3280ec5243. PMID: 17414206

Recent clinical studies

Etiology

Desai AA, Machado RF, Cohen RT
Hematol Oncol Clin North Am 2022 Dec;36(6):1217-1237. doi: 10.1016/j.hoc.2022.07.014. PMID: 36400540Free PMC Article
Freire C, Sennes LU, Polotsky VY
J Clin Sleep Med 2022 Feb 1;18(2):647-652. doi: 10.5664/jcsm.9730. PMID: 34672945Free PMC Article
Trzepizur W, Blanchard M, Ganem T, Balusson F, Feuilloy M, Girault JM, Meslier N, Oger E, Paris A, Pigeanne T, Racineux JL, Sabil A, Gervès-Pinquié C, Gagnadoux F
Am J Respir Crit Care Med 2022 Jan 1;205(1):108-117. doi: 10.1164/rccm.202105-1274OC. PMID: 34648724
Cowie MR, Linz D, Redline S, Somers VK, Simonds AK
J Am Coll Cardiol 2021 Aug 10;78(6):608-624. doi: 10.1016/j.jacc.2021.05.048. PMID: 34353537
Mesarwi OA, Loomba R, Malhotra A
Am J Respir Crit Care Med 2019 Apr 1;199(7):830-841. doi: 10.1164/rccm.201806-1109TR. PMID: 30422676Free PMC Article

Diagnosis

Toups K, Hathaway A, Gordon D, Chung H, Raji C, Boyd A, Hill BD, Hausman-Cohen S, Attarha M, Chwa WJ, Jarrett M, Bredesen DE
J Alzheimers Dis 2022;88(4):1411-1421. doi: 10.3233/JAD-215707. PMID: 35811518Free PMC Article
Trzepizur W, Blanchard M, Ganem T, Balusson F, Feuilloy M, Girault JM, Meslier N, Oger E, Paris A, Pigeanne T, Racineux JL, Sabil A, Gervès-Pinquié C, Gagnadoux F
Am J Respir Crit Care Med 2022 Jan 1;205(1):108-117. doi: 10.1164/rccm.202105-1274OC. PMID: 34648724
Reiter J, Breuer O, Cohen-Cymberknoh M, Forno E, Gileles-Hillel A
Pediatr Pulmonol 2022 Aug;57(8):1944-1951. Epub 2021 May 20 doi: 10.1002/ppul.25462. PMID: 33974362Free PMC Article
Cowie MR, Linz D, Redline S, Somers VK, Simonds AK
J Am Coll Cardiol 2021 Aug 10;78(6):608-624. doi: 10.1016/j.jacc.2021.05.048. PMID: 34353537
Jagpal SK, Jobanputra AM, Ahmed OH, Santiago TV, Ramagopal M
Pediatr Pulmonol 2021 Feb;56 Suppl 1:S23-S31. doi: 10.1002/ppul.25028. PMID: 33263201

Therapy

Toups K, Hathaway A, Gordon D, Chung H, Raji C, Boyd A, Hill BD, Hausman-Cohen S, Attarha M, Chwa WJ, Jarrett M, Bredesen DE
J Alzheimers Dis 2022;88(4):1411-1421. doi: 10.3233/JAD-215707. PMID: 35811518Free PMC Article
Freire C, Sennes LU, Polotsky VY
J Clin Sleep Med 2022 Feb 1;18(2):647-652. doi: 10.5664/jcsm.9730. PMID: 34672945Free PMC Article
Cowie MR, Linz D, Redline S, Somers VK, Simonds AK
J Am Coll Cardiol 2021 Aug 10;78(6):608-624. doi: 10.1016/j.jacc.2021.05.048. PMID: 34353537
Mehta V, Vasu TS, Phillips B, Chung F
J Clin Sleep Med 2013 Mar 15;9(3):271-9. doi: 10.5664/jcsm.2500. PMID: 23493498Free PMC Article
Smith PD, Gotz VP, Ryerson GG
Drug Intell Clin Pharm 1987 May;21(5):417-21. doi: 10.1177/106002808702100503. PMID: 3556128

Prognosis

Barbero E, Rodríguez C, Mañas E, Retegui A, García-Ortega A, García-Sánchez A, Cano-Pumarega I, Martinez-Garcia MÁ, Jimenez D
Int J Cardiol 2023 Oct 15;389:131148. Epub 2023 Jul 7 doi: 10.1016/j.ijcard.2023.131148. PMID: 37423569
Welsner M, Dietz-Terjung S, Stehling F, Schulte T, Niehammer U, Gahbiche FE, Taube C, Strassburg S, Schoebel C, Weinreich G, Sutharsan S
BMC Pulm Med 2022 Nov 28;22(1):446. doi: 10.1186/s12890-022-02243-0. PMID: 36437445Free PMC Article
Perger E, Baillieul S, Esteve F, Pichon A, Bilo G, Soranna D, Doutreleau S, Savina Y, Ulliel-Roche M, Brugniaux JV, Stauffer E, Oberholzer L, Howe C, Hannco I, Lombardi C, Tamisier R, Pepin JL, Verges S, Parati G
Ann Med 2022 Dec;54(1):1884-1893. doi: 10.1080/07853890.2022.2091791. PMID: 35786084Free PMC Article
Trzepizur W, Blanchard M, Ganem T, Balusson F, Feuilloy M, Girault JM, Meslier N, Oger E, Paris A, Pigeanne T, Racineux JL, Sabil A, Gervès-Pinquié C, Gagnadoux F
Am J Respir Crit Care Med 2022 Jan 1;205(1):108-117. doi: 10.1164/rccm.202105-1274OC. PMID: 34648724
Cowie MR, Linz D, Redline S, Somers VK, Simonds AK
J Am Coll Cardiol 2021 Aug 10;78(6):608-624. doi: 10.1016/j.jacc.2021.05.048. PMID: 34353537

Clinical prediction guides

Welsner M, Dietz-Terjung S, Stehling F, Schulte T, Niehammer U, Gahbiche FE, Taube C, Strassburg S, Schoebel C, Weinreich G, Sutharsan S
BMC Pulm Med 2022 Nov 28;22(1):446. doi: 10.1186/s12890-022-02243-0. PMID: 36437445Free PMC Article
Toups K, Hathaway A, Gordon D, Chung H, Raji C, Boyd A, Hill BD, Hausman-Cohen S, Attarha M, Chwa WJ, Jarrett M, Bredesen DE
J Alzheimers Dis 2022;88(4):1411-1421. doi: 10.3233/JAD-215707. PMID: 35811518Free PMC Article
Perger E, Baillieul S, Esteve F, Pichon A, Bilo G, Soranna D, Doutreleau S, Savina Y, Ulliel-Roche M, Brugniaux JV, Stauffer E, Oberholzer L, Howe C, Hannco I, Lombardi C, Tamisier R, Pepin JL, Verges S, Parati G
Ann Med 2022 Dec;54(1):1884-1893. doi: 10.1080/07853890.2022.2091791. PMID: 35786084Free PMC Article
Trzepizur W, Blanchard M, Ganem T, Balusson F, Feuilloy M, Girault JM, Meslier N, Oger E, Paris A, Pigeanne T, Racineux JL, Sabil A, Gervès-Pinquié C, Gagnadoux F
Am J Respir Crit Care Med 2022 Jan 1;205(1):108-117. doi: 10.1164/rccm.202105-1274OC. PMID: 34648724
Smith PD, Gotz VP, Ryerson GG
Drug Intell Clin Pharm 1987 May;21(5):417-21. doi: 10.1177/106002808702100503. PMID: 3556128

Recent systematic reviews

Tan BKJ, Teo YH, Tan NKW, Yap DWT, Sundar R, Lee CH, See A, Toh ST
J Clin Sleep Med 2022 May 1;18(5):1427-1440. doi: 10.5664/jcsm.9772. PMID: 34755597Free PMC Article
Caporale M, Palmeri R, Corallo F, Muscarà N, Romeo L, Bramanti A, Marino S, Lo Buono V
Sleep Breath 2021 Mar;25(1):29-40. Epub 2020 May 23 doi: 10.1007/s11325-020-02084-3. PMID: 32447633
Zhang Y, Wang W, Yang C, Shen J, Shi M, Wang B
Obes Surg 2019 Feb;29(2):601-608. doi: 10.1007/s11695-018-3573-5. PMID: 30411226
Leong WB, Jadhakhan F, Taheri S, Thomas GN, Adab P
Sleep 2016 Feb 1;39(2):301-8. doi: 10.5665/sleep.5432. PMID: 26414891Free PMC Article
Mehta V, Vasu TS, Phillips B, Chung F
J Clin Sleep Med 2013 Mar 15;9(3):271-9. doi: 10.5664/jcsm.2500. PMID: 23493498Free PMC Article

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