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Mixed cell type kidney Wilms tumor

MedGen UID:
76001
Concept ID:
C0279611
Neoplastic Process
Synonym: Mixed cell type kidney Wilms' tumor
 
Monarch Initiative: MONDO:0003318

Definition

Wilms tumor of the kidney characterized by the presence of blastema, epithelial, and mesenchymal components (triphasic pattern) or a combination of two of them (biphasic pattern). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed cell type kidney Wilms tumor

Professional guidelines

PubMed

Uehara S, Oue T, Nakahata K, Nara K, Ueno T, Owari M, Usui N, Miyamura T, Hashii Y
Eur J Pediatr Surg 2015 Feb;25(1):118-22. Epub 2014 Aug 11 doi: 10.1055/s-0034-1386638. PMID: 25111275
Czernobilsky B, Hohlweg-Majert P, Dallenbach-Hellweg G
Arch Gynecol 1983;233(4):281-94. doi: 10.1007/BF02133803. PMID: 6318673

Recent clinical studies

Etiology

Hwang MJ, Hamza A, Zhang M, Tu SM, Pisters LL, Czerniak B, Guo CC
Am J Surg Pathol 2022 Jan 1;46(1):11-17. doi: 10.1097/PAS.0000000000001789. PMID: 34334690Free PMC Article
Awal HB, Nandula SR, Domingues CC, Dore FJ, Kundu N, Brichacek B, Fakhri M, Elzarki A, Ahmadi N, Safai S, Fosso M, Amdur RL, Sen S
Cardiovasc Diabetol 2020 Jun 3;19(1):72. doi: 10.1186/s12933-020-01046-z. PMID: 32493344Free PMC Article
Yang Y, Niu ZB, Hou Y, Wang CL
J Pediatr Surg 2006 Jun;41(6):1062-6. doi: 10.1016/j.jpedsurg.2006.01.072. PMID: 16769335
Hora M, Hes O, Michal M, Boudová L, Chudácek Z, Kreuzberg B, Klecka J
Int Urol Nephrol 2005;37(4):743-50. doi: 10.1007/s11255-005-1201-5. PMID: 16362592
Adsay NV, Eble JN, Srigley JR, Jones EC, Grignon DJ
Am J Surg Pathol 2000 Jul;24(7):958-70. doi: 10.1097/00000478-200007000-00007. PMID: 10895818

Diagnosis

Kadota K, Haba R, Kushida Y, Katsuki N, Hayashi T, Miyai Y, Bando K, Taoka R, Kakehi Y
Pathol Oncol Res 2009 Dec;15(4):665-9. Epub 2009 Apr 24 doi: 10.1007/s12253-009-9169-6. PMID: 19390992
Argani P
Clin Lab Med 2005 Jun;25(2):379-92. doi: 10.1016/j.cll.2005.01.002. PMID: 15848742
Adsay NV, Eble JN, Srigley JR, Jones EC, Grignon DJ
Am J Surg Pathol 2000 Jul;24(7):958-70. doi: 10.1097/00000478-200007000-00007. PMID: 10895818
Dehner LP
Mod Pathol 1998 Jul;11(7):669-85. PMID: 9688189
Kumar A, Lal B, Singh M, Kapur B
Jpn J Surg 1990 Sep;20(5):585-9. doi: 10.1007/BF02471017. PMID: 2173800

Therapy

Suwabe T, Shibasaki Y, Tamura S, Katagiri T, Fuse K, Ida-Kurasaki T, Ushiki T, Sone H, Narita M, Masuko M
Int J Hematol 2024 Apr;119(4):399-406. Epub 2024 Mar 1 doi: 10.1007/s12185-024-03723-1. PMID: 38427208
Plantinga M, Lo Presti V, de Haar CG, Dünnebach E, Madrigal A, Lindemans CA, Boelens JJ, Nierkens S
Front Immunol 2020;11:559152. Epub 2020 Sep 25 doi: 10.3389/fimmu.2020.559152. PMID: 33101274Free PMC Article
Awal HB, Nandula SR, Domingues CC, Dore FJ, Kundu N, Brichacek B, Fakhri M, Elzarki A, Ahmadi N, Safai S, Fosso M, Amdur RL, Sen S
Cardiovasc Diabetol 2020 Jun 3;19(1):72. doi: 10.1186/s12933-020-01046-z. PMID: 32493344Free PMC Article
Coelho-Dos-Reis JG, Huang J, Tsao T, Pereira FV, Funakoshi R, Nakajima H, Sugiyama H, Tsuji M
Clin Immunol 2016 Jul;168:6-15. Epub 2016 Apr 27 doi: 10.1016/j.clim.2016.04.014. PMID: 27132023Free PMC Article
Adsay NV, Eble JN, Srigley JR, Jones EC, Grignon DJ
Am J Surg Pathol 2000 Jul;24(7):958-70. doi: 10.1097/00000478-200007000-00007. PMID: 10895818

Prognosis

Xiang B, Chen ML, Gao ZQ, Mi T, Shi QL, Dong JJ, Tian XM, Liu F, Wei GH
BMC Med Genomics 2023 Aug 17;16(1):189. doi: 10.1186/s12920-023-01627-3. PMID: 37592341Free PMC Article
Hwang MJ, Hamza A, Zhang M, Tu SM, Pisters LL, Czerniak B, Guo CC
Am J Surg Pathol 2022 Jan 1;46(1):11-17. doi: 10.1097/PAS.0000000000001789. PMID: 34334690Free PMC Article
Jurić I, Pogorelić Z, Kuzmić-Prusac I, Biocić M, Jakovljević G, Stepan J, Zupancić B, Culić S, Kruslin B
Pediatr Surg Int 2010 May;26(5):487-93. Epub 2010 Mar 20 doi: 10.1007/s00383-010-2588-3. PMID: 20306058
Yang Y, Niu ZB, Hou Y, Wang CL
J Pediatr Surg 2006 Jun;41(6):1062-6. doi: 10.1016/j.jpedsurg.2006.01.072. PMID: 16769335
Dehner LP
Mod Pathol 1998 Jul;11(7):669-85. PMID: 9688189

Clinical prediction guides

Xiang B, Chen ML, Gao ZQ, Mi T, Shi QL, Dong JJ, Tian XM, Liu F, Wei GH
BMC Med Genomics 2023 Aug 17;16(1):189. doi: 10.1186/s12920-023-01627-3. PMID: 37592341Free PMC Article
Ohishi Y, Oda Y, Kurihara S, Kaku T, Yasunaga M, Nishimura I, Okuma E, Kobayashi H, Wake N, Tsuneyoshi M
Hum Pathol 2009 Aug;40(8):1168-75. Epub 2009 Apr 14 doi: 10.1016/j.humpath.2009.01.002. PMID: 19368953
Yang Y, Niu ZB, Hou Y, Wang CL
J Pediatr Surg 2006 Jun;41(6):1062-6. doi: 10.1016/j.jpedsurg.2006.01.072. PMID: 16769335
Karth J, Ferrer FA, Perlman E, Hanrahan C, Simons JW, Gearhart JP, Rodriguez R
J Pediatr Surg 2000 Dec;35(12):1749-53. doi: 10.1053/jpsu.2000.19241. PMID: 11101729
Guarino M, Micheli P, Pallotti F, Giordano F
Pathol Res Pract 1999;195(6):379-89. doi: 10.1016/S0344-0338(99)80011-9. PMID: 10399178

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