U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ovarian mucinous cystadenocarcinoma

MedGen UID:
76011
•Concept ID:
C0279665
•
Neoplastic Process
Synonyms: Mucinous cystadenocarcinoma of ovary; Mucinous Cystadenocarcinoma of Ovary; mucinous cystadenocarcinoma of ovary; Mucinous Cystadenocarcinoma of the Ovary; mucinous cystadenocarcinoma of the ovary; Ovarian Mucinous Cystadenocarcinoma; ovarian mucinous cystadenocarcinoma; ovary mucinous cystadenocarcinoma
SNOMED CT: Mucinous cystadenocarcinoma of ovary (254851009)
 
Monarch Initiative: MONDO:0002701

Definition

An invasive cystic adenocarcinoma arising from the ovary. It is characterized by the presence of malignant glandular epithelial cells which contain intracytoplasmic mucin. The malignant cells invade the ovarian stroma and the cystic spaces contain mucoid material. In a minority of cases both ovaries are involved by the tumor. The prognosis for stage I tumors is excellent. Patients with metastases usually have a poor prognosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian mucinous cystadenocarcinoma

Professional guidelines

PubMed

Ovarian needle aspiration in the diagnosis and management of ovarian masses.
Nagamine K, Kondo J, Kaneshiro R, Tauchi-Nishi P, Terada K
J Gynecol Oncol 2017 Jul;28(4):e40. doi: 10.3802/jgo.2017.28.e40. PMID: 28541632Free PMC Article
Treatment of ovarian cancer in young women.
Gershenson DM
Clin Obstet Gynecol 2012 Mar;55(1):65-74. doi: 10.1097/GRF.0b013e318248045b. PMID: 22343230
Management of mucin-producing cystic neoplasms of the pancreas.
Fritz S, Warshaw AL, Thayer SP
Oncologist 2009 Feb;14(2):125-36. Epub 2009 Feb 11 doi: 10.1634/theoncologist.2008-0200. PMID: 19211618Free PMC Article

Recent clinical studies

Etiology

Fertility preservation and refreezing of transplanted ovarian tissue-a potential new way of managing patients with low risk of malignant cell recurrence.
Kristensen SG, Giorgione V, Humaidan P, Alsbjerg B, Bjørn AB, Ernst E, Andersen CY
Fertil Steril 2017 May;107(5):1206-1213. Epub 2017 Apr 19 doi: 10.1016/j.fertnstert.2017.03.017. PMID: 28433369
Expression of c-myc and mutation of the KRAS gene in patients with ovarian mucinous tumors.
Li XS, Sun J, He XL
Genet Mol Res 2015 Sep 9;14(3):10752-9. doi: 10.4238/2015.September.9.14. PMID: 26400304
LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma.
Lin CK, Chao TK, Lai HC, Lee HS
Am J Clin Pathol 2012 Jun;137(6):971-7. doi: 10.1309/AJCPIX0RUO5PGLXD. PMID: 22586057
Effects of antisense oligodeoxynucleotide to follicle-stimulating hormone receptor on the cell proliferation and apoptosis in cells derived from human ovarian mucinous cystadenocarcinoma in Vitro.
Li S, Ma D, Zhu C
J Huazhong Univ Sci Technolog Med Sci 2007 Feb;27(1):95-100. doi: 10.1007/s11596-007-0127-9. PMID: 17393121
Effects of antisense oligodeoxynucleotide to follicle-stimulating hormone receptor on the expression of proliferating cell nuclear antigen and vascular endothelial growth factor in primary culture cells derived from human ovarian mucinous cystadenocarcinoma.
Li S, Liu H, Wang L, Zhu C
J Huazhong Univ Sci Technolog Med Sci 2006;26(1):111-5. doi: 10.1007/BF02828054. PMID: 16711022

Diagnosis

Mucinous cystadenocarcinoma of the ovary in a 14-year-old girl: a case report and literature review.
Li Q, Zou C, Xu Y, Liu S, Yan T
BMC Womens Health 2023 Jul 21;23(1):382. doi: 10.1186/s12905-023-02551-5. PMID: 37479970Free PMC Article
Gingival metastasis of ovarian carcinoma: report of a case and review of the literature.
Munakata R, Sawair FA, Cheng J, Saku T
Int J Oral Maxillofac Surg 2009 Oct;38(10):1123-6. Epub 2009 Jun 7 doi: 10.1016/j.ijom.2009.05.003. PMID: 19505797
Ovarian mucinous cystadenocarcinoma with mural nodule of anaplastic carcinoma and synchronous cervical squamous carcinoma.
Tamiolakis D, Venizelos I, Nikolaidou S, Lambropoulou M, Bolioti S, Papadopoulos N
Cesk Patol 2005 Apr;41(2):66-70. PMID: 15966336
Establishment of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma.
Neungton N, Moongkarndi P, Neungton S, Laohathai K, Srisawat C, Wachirutmanggur L, Thielfoldt R
Asian Pac J Allergy Immunol 1995 Jun;13(1):47-53. PMID: 7488344
Ovarian mucinous cystadenocarcinoma with sarcoma-appearing mural nodule of anaplastic carcinoma.
Tsuruchi N, Kaku T, Kinoshita H, Amada S, Saito T, Kamura T, Tsukamoto N, Nakano H
Gynecol Oncol 1993 Aug;50(2):259-63. doi: 10.1006/gyno.1993.1204. PMID: 8375741

Therapy

A 35 Year Old Bangladeshi Lady with Hereditary Mucinous Ovarian Cancer, Complicated with Omental Metastasis.
Islam MJ, Roshid B, Pervin S, Kabir S, Chigurupati S, Hasan MN
Mymensingh Med J 2019 Apr;28(2):484-489. PMID: 31086172
Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy.
Doi D, Boh Y, Konishi H, Asakura H, Takeshita T
Arch Gynecol Obstet 2009 Oct;280(4):633-6. Epub 2009 Feb 11 doi: 10.1007/s00404-009-0950-2. PMID: 19205713
Cryptococcosis masquerading as a tuboovarian abscess.
Sing Y, Ramdial PK, Ibrahim T
Int J Gynecol Pathol 2008 Jan;27(1):37-40. doi: 10.1097/pgp.0b013e318093fa11. PMID: 18156972
Establishment and characterization of a cell-line originated from human mucinous cystadenocarcinoma of the ovary.
Sato S, Kobayashi Y, Okuma Y, Kondo H, Kanishi Y, Saito K, Kiguchi K
Hum Cell 2002 Sep;15(3):171-7. doi: 10.1111/j.1749-0774.2002.tb00111.x. PMID: 12703547
Ovarian mucinous cystadenocarcinoma with sarcoma-appearing mural nodule of anaplastic carcinoma.
Tsuruchi N, Kaku T, Kinoshita H, Amada S, Saito T, Kamura T, Tsukamoto N, Nakano H
Gynecol Oncol 1993 Aug;50(2):259-63. doi: 10.1006/gyno.1993.1204. PMID: 8375741

Prognosis

LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma.
Lin CK, Chao TK, Lai HC, Lee HS
Am J Clin Pathol 2012 Jun;137(6):971-7. doi: 10.1309/AJCPIX0RUO5PGLXD. PMID: 22586057
Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy.
Doi D, Boh Y, Konishi H, Asakura H, Takeshita T
Arch Gynecol Obstet 2009 Oct;280(4):633-6. Epub 2009 Feb 11 doi: 10.1007/s00404-009-0950-2. PMID: 19205713
Ovarian mucinous cystadenocarcinoma with yolk sac tumor in a 71-year-old woman.
Arai T, Kitayama Y, Koda K
Int J Gynecol Pathol 1999 Jul;18(3):277-80. doi: 10.1097/00004347-199907000-00015. PMID: 12090598
Ovarian mucinous cystadenocarcinoma with sarcoma-like mural nodules.
Kataoka A, Nishida T, Ueyama T, Okina H, Yakushiji M
J Obstet Gynaecol Res 1996 Feb;22(1):51-6. doi: 10.1111/j.1447-0756.1996.tb00936.x. PMID: 8624893
Ovarian mucinous cystadenocarcinoma with sarcoma-appearing mural nodule of anaplastic carcinoma.
Tsuruchi N, Kaku T, Kinoshita H, Amada S, Saito T, Kamura T, Tsukamoto N, Nakano H
Gynecol Oncol 1993 Aug;50(2):259-63. doi: 10.1006/gyno.1993.1204. PMID: 8375741

Clinical prediction guides

LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma.
Lin CK, Chao TK, Lai HC, Lee HS
Am J Clin Pathol 2012 Jun;137(6):971-7. doi: 10.1309/AJCPIX0RUO5PGLXD. PMID: 22586057
Effects of antisense oligodeoxynucleotide to follicle-stimulating hormone receptor on the cell proliferation and apoptosis in cells derived from human ovarian mucinous cystadenocarcinoma in Vitro.
Li S, Ma D, Zhu C
J Huazhong Univ Sci Technolog Med Sci 2007 Feb;27(1):95-100. doi: 10.1007/s11596-007-0127-9. PMID: 17393121
Ovarian mucinous cystadenocarcinoma with malignant mural nodules.
Nakamura E, Shimizu M, Mikami Y, Kawai J, Manabe T
Pathol Int 1998 Aug;48(8):645-8. doi: 10.1111/j.1440-1827.1998.tb03964.x. PMID: 9736414
Human granulocyte-macrophage colony-stimulating factor is a growth factor active on human ovarian cancer cells.
Cimoli G, Russo P, Billi G, Mariani GL, Rovini E, Venturini M
Jpn J Cancer Res 1991 Nov;82(11):1196-8. doi: 10.1111/j.1349-7006.1991.tb01779.x. PMID: 1752777Free PMC Article
Immunohistochemical and immunoelectron microscopic study of an amylase-producing, CA19-9 positive ovarian mucinous cystadenocarcinoma.
Teshima H, Kitamura H, Mizoguchi Y, Hino S, Mizutani K, Mori H, Kigawa T
Gynecol Oncol 1988 Jul;30(3):372-80. doi: 10.1016/0090-8258(88)90251-x. PMID: 2455679

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...