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Middle cerebral artery stenosis

MedGen UID:
760200
•Concept ID:
C1504568
•
Disease or Syndrome
Synonym: Stenosis of middle cerebral artery
SNOMED CT: Stenosis of middle cerebral artery (21290001000004104)
 
HPO: HP:0012493

Definition

Narrowing or constriction of the inner surface (lumen) of the middle cerebral artery. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Middle cerebral artery stenosis

Conditions with this feature

Aortic aneurysm, familial thoracic 4
MedGen UID:
338704
•Concept ID:
C1851504
•
Disease or Syndrome
Any familial thoracic aortic aneurysm and aortic dissection in which the cause of the disease is a mutation in the MYH11 gene.
See: Condition Record
Aortic aneurysm, familial thoracic 4

Professional guidelines

PubMed

Transcranial Color-Coded Sonography Criteria for Moderate and Severe Middle Cerebral Artery Stenosis.
Liu R, Li J, Hua Y, Yang J, Zhao Y, Tian X, Ma Y, Zhao W
Ultrasound Med Biol 2021 Jan;47(1):25-32. Epub 2020 Oct 14 doi: 10.1016/j.ultrasmedbio.2020.09.008. PMID: 33069442
Balloon-expandable stents for treatment of symptomatic middle cerebral artery stenosis: Clinical outcomes during long-term follow-up.
Baik SH, Kwak HS, Chung GH, Hwang SB
Interv Neuroradiol 2018 Dec;24(6):666-673. Epub 2018 Jul 10 doi: 10.1177/1591019918786515. PMID: 29991311Free PMC Article
Pilot study of new diagnostic criteria for middle cerebral artery stenosis by transcranial Doppler.
Hao Q, Gao S, Leung TW, Guo MH, You Y, Wong KS
J Neuroimaging 2010 Apr;20(2):122-9. Epub 2009 Jan 29 doi: 10.1111/j.1552-6569.2008.00337.x. PMID: 19187479

Recent clinical studies

Etiology

Diffusion spectrum imaging of patients with middle cerebral artery stenosis.
Wan X, Xiao Y, Liu Z
Neuroimage Clin 2022;36:103133. Epub 2022 Aug 5 doi: 10.1016/j.nicl.2022.103133. PMID: 35973283Free PMC Article
Microsurgical treatment of middle cerebral artery stenosis or occlusion: a single center experience and literature review.
Zhang L, Wu C, Wang H, Mao L
BMC Surg 2022 Mar 7;22(1):87. doi: 10.1186/s12893-022-01539-6. PMID: 35255875Free PMC Article
Diagnosis of Middle Cerebral Artery Stenosis Using Transcranial Doppler Images Based on Convolutional Neural Network.
Mei YJ, Hu RT, Lin J, Xu HY, Wu LY, Li HP, Ye ZM, Qin C
World Neurosurg 2022 May;161:e118-e125. Epub 2022 Jan 22 doi: 10.1016/j.wneu.2022.01.068. PMID: 35077885
Prevalence and outcome of young stroke patients with middle cerebral artery stenosis.
Xu W, Zhang X, Chen H, Zhao Z, Zhu M
BMC Neurol 2021 Mar 4;21(1):99. doi: 10.1186/s12883-021-02125-8. PMID: 33663425Free PMC Article
Intracranial arterial stenosis.
Carvalho M, Oliveira A, Azevedo E, Bastos-Leite AJ
J Stroke Cerebrovasc Dis 2014 Apr;23(4):599-609. Epub 2013 Jul 11 doi: 10.1016/j.jstrokecerebrovasdis.2013.06.006. PMID: 23850084

Diagnosis

Diagnosis of Middle Cerebral Artery Stenosis Using Transcranial Doppler Images Based on Convolutional Neural Network.
Mei YJ, Hu RT, Lin J, Xu HY, Wu LY, Li HP, Ye ZM, Qin C
World Neurosurg 2022 May;161:e118-e125. Epub 2022 Jan 22 doi: 10.1016/j.wneu.2022.01.068. PMID: 35077885
Transcranial Color-Coded Sonography Criteria for Moderate and Severe Middle Cerebral Artery Stenosis.
Liu R, Li J, Hua Y, Yang J, Zhao Y, Tian X, Ma Y, Zhao W
Ultrasound Med Biol 2021 Jan;47(1):25-32. Epub 2020 Oct 14 doi: 10.1016/j.ultrasmedbio.2020.09.008. PMID: 33069442
Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.
Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW, Liu L
J Stroke Cerebrovasc Dis 2017 Aug;26(8):1760-1765. Epub 2017 May 15 doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. PMID: 28522230
Isolated symptomatic middle cerebral artery stenosis in young adults: clinical prognosis and vascular change.
Song X, Xue S, Wu J, Ren Y
Int J Neurosci 2017 Jul;127(7):573-578. Epub 2016 Aug 2 doi: 10.1080/00207454.2016.1212856. PMID: 27412642
Intracranial arterial stenosis.
Carvalho M, Oliveira A, Azevedo E, Bastos-Leite AJ
J Stroke Cerebrovasc Dis 2014 Apr;23(4):599-609. Epub 2013 Jul 11 doi: 10.1016/j.jstrokecerebrovasdis.2013.06.006. PMID: 23850084

Therapy

Radiographic evidence of cerebral hyperperfusion and reversal following angioplasty and stenting of intracranial carotid and middle cerebral artery stenosis: case report and review of the literature.
Brus-Ramer M, Starke RM, Komotar RJ, Meyers PM
J Neuroimaging 2010 Jul;20(3):280-3. Epub 2009 Feb 13 doi: 10.1111/j.1552-6569.2009.00361.x. PMID: 19226337
Statins for asymptomatic middle cerebral artery stenosis: The Regression of Cerebral Artery Stenosis study.
Mok VC, Lam WW, Chen XY, Wong A, Ng PW, Tsoi TH, Yeung V, Liu R, Soo Y, Leung TW, Wong KS
Cerebrovasc Dis 2009;28(1):18-25. Epub 2009 May 6 doi: 10.1159/000215939. PMID: 19420918
Treatment of symptomatic middle cerebral artery stenosis with balloon-mounted stents: long-term follow-up at a single center.
Miao ZR, Feng L, Li S, Zhu F, Ji X, Jiao L, Ling F
Neurosurgery 2009 Jan;64(1):79-84; discussion 84-5. doi: 10.1227/01.NEU.0000335648.31874.37. PMID: 19050657
Middle cerebral artery stenosis: stenting is one of the options: yes.
Liu M, Li W, Liu ZQ
Stroke 2007 Apr;38(4):1418-9. Epub 2007 Mar 1 doi: 10.1161/01.STR.0000259844.15195.e3. PMID: 17332459
Symptomatic middle cerebral artery stenosis.
Hinton RC, Mohr JP, Ackerman RH, Adair LB, Fisher CM
Ann Neurol 1979 Feb;5(2):152-7. doi: 10.1002/ana.410050208. PMID: 426478

Prognosis

Prevalence and outcome of young stroke patients with middle cerebral artery stenosis.
Xu W, Zhang X, Chen H, Zhao Z, Zhu M
BMC Neurol 2021 Mar 4;21(1):99. doi: 10.1186/s12883-021-02125-8. PMID: 33663425Free PMC Article
Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.
Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, Liu J, Abrigo J, Soo YOY, Liebeskind DS, Wong KS, Leung TW
Eur J Neurol 2018 Feb;25(2):404-410. Epub 2017 Dec 18 doi: 10.1111/ene.13521. PMID: 29171118
Stenosis length of middle cerebral artery and branch atheromatous disease associated infarct.
Wang J, Wang Y, Chai Z, Xin Y, Wang J, Qiu J
Int J Neurosci 2018 Feb;128(2):133-139. Epub 2017 Sep 22 doi: 10.1080/00207454.2017.1377710. PMID: 28882090
Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.
Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW, Liu L
J Stroke Cerebrovasc Dis 2017 Aug;26(8):1760-1765. Epub 2017 May 15 doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. PMID: 28522230
Isolated symptomatic middle cerebral artery stenosis in young adults: clinical prognosis and vascular change.
Song X, Xue S, Wu J, Ren Y
Int J Neurosci 2017 Jul;127(7):573-578. Epub 2016 Aug 2 doi: 10.1080/00207454.2016.1212856. PMID: 27412642

Clinical prediction guides

Microsurgical treatment of middle cerebral artery stenosis or occlusion: a single center experience and literature review.
Zhang L, Wu C, Wang H, Mao L
BMC Surg 2022 Mar 7;22(1):87. doi: 10.1186/s12893-022-01539-6. PMID: 35255875Free PMC Article
Prevalence and outcome of young stroke patients with middle cerebral artery stenosis.
Xu W, Zhang X, Chen H, Zhao Z, Zhu M
BMC Neurol 2021 Mar 4;21(1):99. doi: 10.1186/s12883-021-02125-8. PMID: 33663425Free PMC Article
Stenosis length of middle cerebral artery and branch atheromatous disease associated infarct.
Wang J, Wang Y, Chai Z, Xin Y, Wang J, Qiu J
Int J Neurosci 2018 Feb;128(2):133-139. Epub 2017 Sep 22 doi: 10.1080/00207454.2017.1377710. PMID: 28882090
Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.
Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW, Liu L
J Stroke Cerebrovasc Dis 2017 Aug;26(8):1760-1765. Epub 2017 May 15 doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. PMID: 28522230
Clinical utilization of microembolus detection by transcranial Doppler sonography in intracranial stenosis-occlusive disease.
Wu XJ, Xing YQ, Wang J, Liu KD
Chin Med J (Engl) 2013 Apr;126(7):1355-9. PMID: 23557571

Recent systematic reviews

Statin treatment and accrual of covert cerebral ischaemia on neuroimaging: a systematic review and meta-analysis of randomized trials.
Katsanos AH, Lioutas VA, Charidimou A, Catanese L, Ng KKH, Perera K, de Sa Boasquevisque D, Tsivgoulis G, Smith EE, Sharma M, Selim MH, Shoamanesh A
Eur J Neurol 2020 Jun;27(6):1023-1027. Epub 2020 Mar 23 doi: 10.1111/ene.14196. PMID: 32133735
The accuracy of transcranial Doppler in the diagnosis of middle cerebral artery stenosis.
Navarro JC, Lao AY, Sharma VK, Tsivgoulis G, Alexandrov AV
Cerebrovasc Dis 2007;23(5-6):325-30. Epub 2007 Jan 30 doi: 10.1159/000099130. PMID: 17268162
Outcome in patients with symptomatic occlusion of the internal carotid artery or intracranial arterial lesions: a meta-analysis of the role of baseline characteristics and type of antithrombotic treatment.
Klijn CJ, Kappelle LJ, Algra A, van Gijn J
Cerebrovasc Dis 2001;12(3):228-34. doi: 10.1159/000047708. PMID: 11641588

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