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Malignant Pancreatic Somatostatinoma

MedGen UID:
Concept ID:
Neoplastic Process
Synonyms: Pancreatic Delta Cell Carcinoma; Pancreatic Malignant Somatostatinoma


A neuroendocrine tumor that arises from the delta cells of the pancreas. It is characterized by inappropriate secretion of somatostatin and associated with diabetes mellitus, hypochlorhydria, gallbladder disease, diarrhea, steatorrhea, anemia, and weight loss. It displays vascular invasion and metastasizes to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Pancreatic Somatostatinoma

Professional guidelines


Mastoraki A, Schizas D, Papoutsi E, Ntella V, Kanavidis P, Sioulas A, Tsoli M, Charalampopoulos G, Vailas M, Felekouras E
In Vivo 2020 Nov-Dec;34(6):3573-3582. doi: 10.21873/invivo.12201. PMID: 33144470Free PMC Article
Parbhu SK, Adler DG
Hosp Pract (1995) 2016 Aug;44(3):109-19. Epub 2016 Jul 18 doi: 10.1080/21548331.2016.1210474. PMID: 27404266
Ito T, Igarashi H, Jensen RT
Best Pract Res Clin Gastroenterol 2012 Dec;26(6):737-53. doi: 10.1016/j.bpg.2012.12.003. PMID: 23582916Free PMC Article

Recent clinical studies


Abe T, Oshida K, Matsumoto K, Iida M, Sanno N
J Neurosurg 1996 Oct;85(4):681-4. doi: 10.3171/jns.1996.85.4.0681. PMID: 8814175


Levi S, Bjarnason I, Swinson CM, Polak JM, Murray W, Levi AJ
Digestion 1988;39(1):1-6. doi: 10.1159/000199601. PMID: 2899527

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