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Malignant Pancreatic Somatostatinoma

MedGen UID:
76021
Concept ID:
C0279727
Neoplastic Process
Synonyms: Pancreatic Delta Cell Carcinoma; Pancreatic Malignant Somatostatinoma

Definition

A neuroendocrine tumor that arises from the delta cells of the pancreas. It is characterized by inappropriate secretion of somatostatin and associated with diabetes mellitus, hypochlorhydria, gallbladder disease, diarrhea, steatorrhea, anemia, and weight loss. It displays vascular invasion and metastasizes to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Pancreatic Somatostatinoma

Professional guidelines

PubMed

Mastoraki A, Schizas D, Papoutsi E, Ntella V, Kanavidis P, Sioulas A, Tsoli M, Charalampopoulos G, Vailas M, Felekouras E
In Vivo 2020 Nov-Dec;34(6):3573-3582. doi: 10.21873/invivo.12201. PMID: 33144470Free PMC Article
Parbhu SK, Adler DG
Hosp Pract (1995) 2016 Aug;44(3):109-19. Epub 2016 Jul 18 doi: 10.1080/21548331.2016.1210474. PMID: 27404266
Ito T, Igarashi H, Jensen RT
Best Pract Res Clin Gastroenterol 2012 Dec;26(6):737-53. doi: 10.1016/j.bpg.2012.12.003. PMID: 23582916Free PMC Article

Recent clinical studies

Diagnosis

Abe T, Oshida K, Matsumoto K, Iida M, Sanno N
J Neurosurg 1996 Oct;85(4):681-4. doi: 10.3171/jns.1996.85.4.0681. PMID: 8814175

Therapy

Levi S, Bjarnason I, Swinson CM, Polak JM, Murray W, Levi AJ
Digestion 1988;39(1):1-6. doi: 10.1159/000199601. PMID: 2899527

Supplemental Content

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