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Intermediate Grade Salivary Gland Mucoepidermoid Carcinoma

MedGen UID:
76023
Concept ID:
C0279742
Neoplastic Process
Synonyms: Grade II Mucoepidermoid Carcinoma of Salivary Gland; Grade II Mucoepidermoid Carcinoma of the Salivary Gland; Grade II Salivary Gland Mucoepidermoid Carcinoma

Definition

A salivary gland mucoepidermoid carcinoma with intermediate grade histopathologic features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntermediate Grade Salivary Gland Mucoepidermoid Carcinoma

Professional guidelines

PubMed

Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Kalhor N, Moran CA
Expert Rev Respir Med 2018 Mar;12(3):249-255. Epub 2018 Jan 17 doi: 10.1080/17476348.2018.1428563. PMID: 29338644
Auclair PL, Goode RK, Ellis GL
Cancer 1992 Apr 15;69(8):2021-30. doi: 10.1002/1097-0142(19920415)69:8<2021::aid-cncr2820690803>3.0.co;2-7. PMID: 1544111

Recent clinical studies

Etiology

Venetis K, Sajjadi E, Ivanova M, Andaloro S, Pessina S, Zanetti C, Ranghiero A, Citelli G, Rossi C, Lucioni M, Malapelle U, Pagni F, Barberis M, Guerini-Rocco E, Viale G, Fusco N
Cancer Med 2023 May;12(9):10725-10737. Epub 2023 Mar 14 doi: 10.1002/cam4.5754. PMID: 36916425Free PMC Article
Richards HW, Bertelsen C, Hamilton B, Sauer D, Schindler J
Ann Otol Rhinol Laryngol 2022 Dec;131(12):1398-1403. Epub 2022 Jan 6 doi: 10.1177/00034894211069459. PMID: 34991344
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Stenman G
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S12-9. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0462-z. PMID: 23821214Free PMC Article

Diagnosis

Murase T, Nakano S, Sakane T, Domen H, Chiyo M, Nagasaka S, Tanaka M, Kawahara Y, Toishi M, Tanaka T, Nakamura S, Sawabata N, Okami J, Mukaida H, Tzankov A, Szolkowska M, Porubsky S, Marx A, Roden AC, Inagaki H
Am J Surg Pathol 2022 Aug 1;46(8):1160-1169. Epub 2022 Mar 22 doi: 10.1097/PAS.0000000000001886. PMID: 35319525
Richards HW, Bertelsen C, Hamilton B, Sauer D, Schindler J
Ann Otol Rhinol Laryngol 2022 Dec;131(12):1398-1403. Epub 2022 Jan 6 doi: 10.1177/00034894211069459. PMID: 34991344
Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article
Peraza A, Gómez R, Beltran J, Amarista FJ
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):713-720. Epub 2020 Jun 18 doi: 10.1016/j.jormas.2020.06.003. PMID: 32565266
Kalhor N, Moran CA
Expert Rev Respir Med 2018 Mar;12(3):249-255. Epub 2018 Jan 17 doi: 10.1080/17476348.2018.1428563. PMID: 29338644

Therapy

Mayer M, Nachtsheim L, Hoffmann F, von Eggeling F, Guntinas-Lichius O, Prinz J, Klußmann JP, Quaas A, Arolt C, Wolber P
Int J Mol Sci 2022 Aug 12;23(16) doi: 10.3390/ijms23169037. PMID: 36012301Free PMC Article
Dahan LS, Giorgi R, Vergez S, Le Taillandier de Gabory L, Costes-Martineau V, Herman P, Poissonnet G, Mauvais O, Malard O, Garrel R, Uro-Coste E, Barry B, Bach C, Chevalier D, Mouawad F, Merol JC, Bastit V, Thariat J, Gilain L, Dufour X, Righini CA, Moya-Plana A, Even C, Radulesco T, Michel J, Baujat B, Fakhry N; REFCOR members
Eur J Surg Oncol 2021 Jun;47(6):1376-1383. Epub 2020 Nov 21 doi: 10.1016/j.ejso.2020.11.123. PMID: 33248902
Richter SM, Friedmann P, Mourad WF, Hu KS, Persky MS, Harrison LB
Head Neck 2012 Jul;34(7):953-5. Epub 2011 Aug 17 doi: 10.1002/hed.21843. PMID: 21850698

Prognosis

Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article
Stenman G
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S12-9. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0462-z. PMID: 23821214Free PMC Article
Bell D, El-Naggar AK
Head Neck Pathol 2013 Mar;7(1):23-7. Epub 2013 Mar 5 doi: 10.1007/s12105-013-0432-5. PMID: 23459841Free PMC Article
Seethala RR
Adv Anat Pathol 2011 Jan;18(1):29-45. doi: 10.1097/PAP.0b013e318202645a. PMID: 21169736
Luna MA
Adv Anat Pathol 2006 Nov;13(6):293-307. doi: 10.1097/01.pap.0000213058.74509.d3. PMID: 17075295

Clinical prediction guides

Venetis K, Sajjadi E, Ivanova M, Andaloro S, Pessina S, Zanetti C, Ranghiero A, Citelli G, Rossi C, Lucioni M, Malapelle U, Pagni F, Barberis M, Guerini-Rocco E, Viale G, Fusco N
Cancer Med 2023 May;12(9):10725-10737. Epub 2023 Mar 14 doi: 10.1002/cam4.5754. PMID: 36916425Free PMC Article
Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article
Rajasekaran K, Stubbs V, Chen J, Yalamanchi P, Cannady S, Brant J, Newman J
Am J Otolaryngol 2018 May-Jun;39(3):321-326. Epub 2018 Mar 14 doi: 10.1016/j.amjoto.2018.03.022. PMID: 29559174
Seethala RR
Adv Anat Pathol 2011 Jan;18(1):29-45. doi: 10.1097/PAP.0b013e318202645a. PMID: 21169736
Rapidis AD, Givalos N, Gakiopoulou H, Stavrianos SD, Faratzis G, Lagogiannis GA, Katsilieris I, Patsouris E
Oral Oncol 2007 Feb;43(2):130-6. Epub 2006 Jul 20 doi: 10.1016/j.oraloncology.2006.03.001. PMID: 16857410

Recent systematic reviews

Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810

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