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High Grade Atrioventricular Block by ECG Finding

MedGen UID:
760522
•Concept ID:
C2363939
•
Finding
Synonyms: Advanced Atrioventricular Block; High Grade Atrioventricular Block; High Grade Atrioventricular Block by EKG Finding

Definition

An electrocardiographic finding of intermittent failure of atrial electrical impulse conduction to the ventricles, characterized by two or more consecutive non-conducted P waves. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHigh Grade Atrioventricular Block by ECG Finding

Professional guidelines

PubMed

Epidemiology, evaluation, and management of conduction disturbances after transcatheter aortic valve replacement.
Aymond JD, Benn F, Williams CM, Bernard ML, Hiltbold AE, Khatib S, Polin GM, Rogers PA, Tafur Soto JD, Ramee SR, Parrino PE, Falterman JB, Al-Khatib SM, Morin DP
Prog Cardiovasc Dis 2021 May-Jun;66:37-45. doi: 10.1016/j.pcad.2021.06.004. PMID: 34332660
2020 ACC Expert Consensus Decision Pathway on Management of Conduction Disturbances in Patients Undergoing Transcatheter Aortic Valve Replacement: A Report of the American College of Cardiology Solution Set Oversight Committee.
Lilly SM, Deshmukh AJ, Epstein AE, Ricciardi MJ, Shreenivas S, Velagapudi P, Wyman JF
J Am Coll Cardiol 2020 Nov 17;76(20):2391-2411. Epub 2020 Oct 21 doi: 10.1016/j.jacc.2020.08.050. PMID: 33190683
Variant angina and coronary artery spasm: the clinical spectrum, pathophysiology, and management.
Kusama Y, Kodani E, Nakagomi A, Otsuka T, Atarashi H, Kishida H, Mizuno K
J Nippon Med Sch 2011;78(1):4-12. doi: 10.1272/jnms.78.4. PMID: 21389642

Recent clinical studies

Etiology

Obesity and Cardiac Conduction Block Disease in China.
Liu P, Wang Y, Zhang X, Zhang Z, Zhao N, Ou W, Wang G, Yang X, Li M, Zhang Y, Yang X, Wu S
JAMA Netw Open 2023 Nov 1;6(11):e2342831. doi: 10.1001/jamanetworkopen.2023.42831. PMID: 37955899Free PMC Article
High-grade atrioventricular block in acute coronary syndrome: Portuguese experience.
Santos H, Santos M, Almeida I, Paula SB, Chin J, Almeida S, Almeida L; Portuguese Registry of Acute Coronary Syndromes
J Electrocardiol 2021 Sep-Oct;68:130-134. Epub 2021 Aug 16 doi: 10.1016/j.jelectrocard.2021.08.002. PMID: 34419648
Meningitis and high-grade, second-degree atrioventricular block in an adolescent: causal effect or coincidence?
Murphy LD, Florez AR, Czosek RJ, Cooper DS, Mah KE
Cardiol Young 2021 Nov;31(11):1873-1875. Epub 2021 May 10 doi: 10.1017/S1047951121001785. PMID: 33966681
Temporal Incidence and Predictors of High-Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.
El-Sabawi B, Welle GA, Cha YM, Espinosa RE, Gulati R, Sandhu GS, Greason KL, Crestanello JA, Friedman PA, Munger TM, Rihal CS, Eleid MF
J Am Heart Assoc 2021 May 18;10(10):e020033. Epub 2021 May 7 doi: 10.1161/JAHA.120.020033. PMID: 33960210Free PMC Article
Incidence, Predictors, and Implications of Permanent Pacemaker Requirement After Transcatheter Aortic Valve Replacement.
Sammour Y, Krishnaswamy A, Kumar A, Puri R, Tarakji KG, Bazarbashi N, Harb S, Griffin B, Svensson L, Wazni O, Kapadia SR
JACC Cardiovasc Interv 2021 Jan 25;14(2):115-134. doi: 10.1016/j.jcin.2020.09.063. PMID: 33478630

Diagnosis

Obesity and Cardiac Conduction Block Disease in China.
Liu P, Wang Y, Zhang X, Zhang Z, Zhao N, Ou W, Wang G, Yang X, Li M, Zhang Y, Yang X, Wu S
JAMA Netw Open 2023 Nov 1;6(11):e2342831. doi: 10.1001/jamanetworkopen.2023.42831. PMID: 37955899Free PMC Article
High-grade atrioventricular block in acute coronary syndrome: Portuguese experience.
Santos H, Santos M, Almeida I, Paula SB, Chin J, Almeida S, Almeida L; Portuguese Registry of Acute Coronary Syndromes
J Electrocardiol 2021 Sep-Oct;68:130-134. Epub 2021 Aug 16 doi: 10.1016/j.jelectrocard.2021.08.002. PMID: 34419648
Meningitis and high-grade, second-degree atrioventricular block in an adolescent: causal effect or coincidence?
Murphy LD, Florez AR, Czosek RJ, Cooper DS, Mah KE
Cardiol Young 2021 Nov;31(11):1873-1875. Epub 2021 May 10 doi: 10.1017/S1047951121001785. PMID: 33966681
High-Grade Atrioventricular Block Associated With Acute Influenza.
Ergle K, Gooden JY, Ahmed MM
Tex Heart Inst J 2020 Jun 1;47(3):220-223. doi: 10.14503/THIJ-18-6658. PMID: 32997780Free PMC Article
High-grade atrioventricular block.
Lim Y, Singh D, Poh KK
Singapore Med J 2018 Jul;59(7):346-350. doi: 10.11622/smedj.2018086. PMID: 30109349Free PMC Article

Therapy

The future of cardioneuroablation in cardiovascular medicine.
Aksu T, Khan A, Huang H
Expert Rev Cardiovasc Ther 2022 Nov;20(11):861-870. Epub 2022 Nov 15 doi: 10.1080/14779072.2022.2147926. PMID: 36376271
Epidemiology, evaluation, and management of conduction disturbances after transcatheter aortic valve replacement.
Aymond JD, Benn F, Williams CM, Bernard ML, Hiltbold AE, Khatib S, Polin GM, Rogers PA, Tafur Soto JD, Ramee SR, Parrino PE, Falterman JB, Al-Khatib SM, Morin DP
Prog Cardiovasc Dis 2021 May-Jun;66:37-45. doi: 10.1016/j.pcad.2021.06.004. PMID: 34332660
Temporal Incidence and Predictors of High-Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.
El-Sabawi B, Welle GA, Cha YM, Espinosa RE, Gulati R, Sandhu GS, Greason KL, Crestanello JA, Friedman PA, Munger TM, Rihal CS, Eleid MF
J Am Heart Assoc 2021 May 18;10(10):e020033. Epub 2021 May 7 doi: 10.1161/JAHA.120.020033. PMID: 33960210Free PMC Article
Transcatheter aortic valve replacement and cardiac conduction.
Shreenivas S, Schloss E, Choo J, Sarembock I, Lilly S, Kereiakes D
Expert Rev Cardiovasc Ther 2019 Apr;17(4):293-304. doi: 10.1080/14779072.2019.1598264. PMID: 30912984
Impact of high-grade atrioventricular block and cumulative frequent pacing on atrial arrhythmias.
Wali E, Deshmukh A, Bukari A, Broman M, Aziz Z, Beaser A, Upadhyay G, Nayak HM, Tung R, Ozcan C
Pacing Clin Electrophysiol 2018 Sep;41(9):1158-1164. Epub 2018 Jul 16 doi: 10.1111/pace.13425. PMID: 29931776Free PMC Article

Prognosis

High-grade atrioventricular block in acute coronary syndrome: Portuguese experience.
Santos H, Santos M, Almeida I, Paula SB, Chin J, Almeida S, Almeida L; Portuguese Registry of Acute Coronary Syndromes
J Electrocardiol 2021 Sep-Oct;68:130-134. Epub 2021 Aug 16 doi: 10.1016/j.jelectrocard.2021.08.002. PMID: 34419648
Temporal Incidence and Predictors of High-Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.
El-Sabawi B, Welle GA, Cha YM, Espinosa RE, Gulati R, Sandhu GS, Greason KL, Crestanello JA, Friedman PA, Munger TM, Rihal CS, Eleid MF
J Am Heart Assoc 2021 May 18;10(10):e020033. Epub 2021 May 7 doi: 10.1161/JAHA.120.020033. PMID: 33960210Free PMC Article
Incidence, Predictors, and Implications of Permanent Pacemaker Requirement After Transcatheter Aortic Valve Replacement.
Sammour Y, Krishnaswamy A, Kumar A, Puri R, Tarakji KG, Bazarbashi N, Harb S, Griffin B, Svensson L, Wazni O, Kapadia SR
JACC Cardiovasc Interv 2021 Jan 25;14(2):115-134. doi: 10.1016/j.jcin.2020.09.063. PMID: 33478630
Transcatheter aortic valve replacement and cardiac conduction.
Shreenivas S, Schloss E, Choo J, Sarembock I, Lilly S, Kereiakes D
Expert Rev Cardiovasc Ther 2019 Apr;17(4):293-304. doi: 10.1080/14779072.2019.1598264. PMID: 30912984
Impact of high-grade atrioventricular block and cumulative frequent pacing on atrial arrhythmias.
Wali E, Deshmukh A, Bukari A, Broman M, Aziz Z, Beaser A, Upadhyay G, Nayak HM, Tung R, Ozcan C
Pacing Clin Electrophysiol 2018 Sep;41(9):1158-1164. Epub 2018 Jul 16 doi: 10.1111/pace.13425. PMID: 29931776Free PMC Article

Clinical prediction guides

High-grade atrioventricular block in acute coronary syndrome: Portuguese experience.
Santos H, Santos M, Almeida I, Paula SB, Chin J, Almeida S, Almeida L; Portuguese Registry of Acute Coronary Syndromes
J Electrocardiol 2021 Sep-Oct;68:130-134. Epub 2021 Aug 16 doi: 10.1016/j.jelectrocard.2021.08.002. PMID: 34419648
Temporal Incidence and Predictors of High-Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.
El-Sabawi B, Welle GA, Cha YM, Espinosa RE, Gulati R, Sandhu GS, Greason KL, Crestanello JA, Friedman PA, Munger TM, Rihal CS, Eleid MF
J Am Heart Assoc 2021 May 18;10(10):e020033. Epub 2021 May 7 doi: 10.1161/JAHA.120.020033. PMID: 33960210Free PMC Article
Incidence, Predictors, and Implications of Permanent Pacemaker Requirement After Transcatheter Aortic Valve Replacement.
Sammour Y, Krishnaswamy A, Kumar A, Puri R, Tarakji KG, Bazarbashi N, Harb S, Griffin B, Svensson L, Wazni O, Kapadia SR
JACC Cardiovasc Interv 2021 Jan 25;14(2):115-134. doi: 10.1016/j.jcin.2020.09.063. PMID: 33478630
Impact of high-grade atrioventricular block and cumulative frequent pacing on atrial arrhythmias.
Wali E, Deshmukh A, Bukari A, Broman M, Aziz Z, Beaser A, Upadhyay G, Nayak HM, Tung R, Ozcan C
Pacing Clin Electrophysiol 2018 Sep;41(9):1158-1164. Epub 2018 Jul 16 doi: 10.1111/pace.13425. PMID: 29931776Free PMC Article
Intramyocardial block in patients with atrioventricular block.
Li G, Saguner AM, Akdis D, Fontaine GH
J Investig Med 2018 Jun;66(5):1-4. Epub 2018 Mar 7 doi: 10.1136/jim-2017-000682. PMID: 29514866

Recent systematic reviews

Effect of shenmai injection on anthracycline-induced cardiotoxicity: A systematic review and meta-analysis.
Yang L, Liu X, Yang W, Wang S, Li Z, Lei Y, Liu D
Complement Ther Med 2024 Aug;83:103053. Epub 2024 May 25 doi: 10.1016/j.ctim.2024.103053. PMID: 38801910

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