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Childhood Leiomyosarcoma

MedGen UID:
76054
•Concept ID:
C0279986
•
Neoplastic Process
Synonym: Pediatric Leiomyosarcoma

Definition

An aggressive malignant smooth muscle neoplasm, occurring in children. It is characterized by a proliferation of neoplastic spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Leiomyosarcoma

Professional guidelines

PubMed

Treatment for leiomyosarcoma and leiomyoma in children with HIV infection.
Yin X, Wu T, Yan Y, Zhang H, Bu H
Cochrane Database Syst Rev 2010 May 12;(5):CD007665. doi: 10.1002/14651858.CD007665.pub2. PMID: 20464756

Recent clinical studies

Etiology

Childhood leiomyosarcoma: a report from the soft tissue sarcoma Italian Cooperative Group.
Ferrari A, Bisogno G, Casanova M, Meazza C, Cecchetto G, Mancini MA, Zanetti I, Alaggio R, Ninfo V, Carli M
Ann Oncol 2001 Aug;12(8):1163-8. doi: 10.1023/a:1011676813582. PMID: 11583201
AIDS-related cancers in Africa: maturation of the epidemic in Uganda.
Parkin DM, Wabinga H, Nambooze S, Wabwire-Mangen F
AIDS 1999 Dec 24;13(18):2563-70. doi: 10.1097/00002030-199912240-00010. PMID: 10630526
Overview of the epidemiology of immunodeficiency-associated cancers.
Beral V, Newton R
J Natl Cancer Inst Monogr 1998;(23):1-6. doi: 10.1093/oxfordjournals.jncimonographs.a024164. PMID: 9709294

Diagnosis

Primary leiomyosarcoma of brain in an adolescent with common variable immunodeficiency syndrome.
Mierau GW, Greffe BS, Weeks DA
Ultrastruct Pathol 1997 May-Jun;21(3):301-5. doi: 10.3109/01913129709021926. PMID: 9183831

Prognosis

Childhood leiomyosarcoma: a report from the soft tissue sarcoma Italian Cooperative Group.
Ferrari A, Bisogno G, Casanova M, Meazza C, Cecchetto G, Mancini MA, Zanetti I, Alaggio R, Ninfo V, Carli M
Ann Oncol 2001 Aug;12(8):1163-8. doi: 10.1023/a:1011676813582. PMID: 11583201
AIDS-related cancers in Africa: maturation of the epidemic in Uganda.
Parkin DM, Wabinga H, Nambooze S, Wabwire-Mangen F
AIDS 1999 Dec 24;13(18):2563-70. doi: 10.1097/00002030-199912240-00010. PMID: 10630526

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