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Sexual Dysfunction and Infertility

MedGen UID:
76197
•Concept ID:
C0280958
•
Disease or Syndrome
Synonym: dysfunction and infertility, sexual

Professional guidelines

PubMed

Genotype and clinical phenotype analysis of a Family with Kennedy disease.
Cai BC, Zhong LF, Liu YH, Sui ZY, Yang Q, Zeng DT, Li X, Xu WD, Chen T
Medicine (Baltimore) 2023 Apr 14;102(15):e33502. doi: 10.1097/MD.0000000000033502. PMID: 37058074Free PMC Article
Hypogonadism in male thalassemia major patients: pathophysiology, diagnosis and treatment.
De Sanctis V, Soliman AT, Yassin MA, Di Maio S, Daar S, Elsedfy H, Soliman N, Kattamis C
Acta Biomed 2018 Feb 16;89(2-S):6-15. doi: 10.23750/abm.v89i2-S.7082. PMID: 29451224Free PMC Article
Sexual function and fertility after treatment of testicular cancer.
Kuczyk M, Machtens S, Bokemeyer C, Schultheiss D, Jonas U
Curr Opin Urol 2000 Sep;10(5):473-7. doi: 10.1097/00042307-200009000-00018. PMID: 11005454

Recent clinical studies

Etiology

Investigation of the female infertility risk associated with anti-cancer therapy.
Lavafian A, Pezeshki PS, Rezaei N
Clin Transl Oncol 2023 Jul;25(7):1893-1905. Epub 2023 Jan 23 doi: 10.1007/s12094-023-03087-8. PMID: 36689055
Metabolically healthy and unhealthy obesity in erectile dysfunction and male infertility.
Rastrelli G, Lotti F, Reisman Y, Sforza A, Maggi M, Corona G
Expert Rev Endocrinol Metab 2019 Sep;14(5):321-334. Epub 2019 Aug 29 doi: 10.1080/17446651.2019.1657827. PMID: 31464531
Food with Influence in the Sexual and Reproductive Health.
Silva T, Jesus M, Cagigal C, Silva C
Curr Pharm Biotechnol 2019;20(2):114-122. doi: 10.2174/1389201019666180925140400. PMID: 30255750
Sexual and reproductive issues and inflammatory bowel disease: a neglected topic in men.
Allocca M, Gilardi D, Fiorino G, Furfaro F, Peyrin-Biroulet L, Danese S
Eur J Gastroenterol Hepatol 2018 Mar;30(3):316-322. doi: 10.1097/MEG.0000000000001074. PMID: 29351114
Sexual dysfunction in infertile women: A systematic review and meta-analysis.
Mendonça CR, Arruda JT, Noll M, Campoli PMO, Amaral WND
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:153-163. Epub 2017 Jun 7 doi: 10.1016/j.ejogrb.2017.06.013. PMID: 28628848

Diagnosis

Rare forms of genetic steroidogenic defects affecting the gonads and adrenals.
Boettcher C, Flück CE
Best Pract Res Clin Endocrinol Metab 2022 Jan;36(1):101593. Epub 2021 Oct 12 doi: 10.1016/j.beem.2021.101593. PMID: 34711511
Nonalcoholic Fatty Liver Disease, Male Sexual Dysfunction, and Infertility: Common Links, Common Problems.
Hawksworth DJ, Burnett AL
Sex Med Rev 2020 Apr;8(2):274-285. Epub 2019 Mar 19 doi: 10.1016/j.sxmr.2019.01.002. PMID: 30898592
Sexual and reproductive health in cancer survivors.
Goldfarb S, Mulhall J, Nelson C, Kelvin J, Dickler M, Carter J
Semin Oncol 2013 Dec;40(6):726-44. doi: 10.1053/j.seminoncol.2013.09.002. PMID: 24331193
Urological complications following inguinal hernioplasty.
Gulino G, Antonucci M, Palermo G, Sasso F, Tienforti D, D'Addessi A, Bassi PF
Arch Ital Urol Androl 2012 Sep;84(3):105-10. PMID: 23210400
Prolactin and male reproduction.
Hermanns U, Hafez ES
Arch Androl 1981 Mar;6(2):95-125. doi: 10.3109/01485018108987351. PMID: 6788004

Therapy

Investigation of the female infertility risk associated with anti-cancer therapy.
Lavafian A, Pezeshki PS, Rezaei N
Clin Transl Oncol 2023 Jul;25(7):1893-1905. Epub 2023 Jan 23 doi: 10.1007/s12094-023-03087-8. PMID: 36689055
Botanicals in health and disease of the testis and male fertility: A scoping review.
Shepherd A, Brunckhorst O, Ahmed K, Xu Q
Phytomedicine 2022 Nov;106:154398. Epub 2022 Aug 19 doi: 10.1016/j.phymed.2022.154398. PMID: 36049429
Sexual and reproductive issues and inflammatory bowel disease: a neglected topic in men.
Allocca M, Gilardi D, Fiorino G, Furfaro F, Peyrin-Biroulet L, Danese S
Eur J Gastroenterol Hepatol 2018 Mar;30(3):316-322. doi: 10.1097/MEG.0000000000001074. PMID: 29351114
Sexual dysfunction in infertile women: A systematic review and meta-analysis.
Mendonça CR, Arruda JT, Noll M, Campoli PMO, Amaral WND
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:153-163. Epub 2017 Jun 7 doi: 10.1016/j.ejogrb.2017.06.013. PMID: 28628848
Male sexual dysfunction and infertility associated with neurological disorders.
Fode M, Krogh-Jespersen S, Brackett NL, Ohl DA, Lynne CM, Sønksen J
Asian J Androl 2012 Jan;14(1):61-8. Epub 2011 Dec 5 doi: 10.1038/aja.2011.70. PMID: 22138899Free PMC Article

Prognosis

Transsphenoidal surgery for prolactinomas in male patients: a retrospective study.
Su WJ, Cai HC, Yang GC, He KJ, Wu HL, Yang YB, Tang HX, Yang LX, Deng CH
Asian J Androl 2023 Jan-Feb;25(1):113-118. doi: 10.4103/aja202233. PMID: 35645047Free PMC Article
Pituitary apoplexy of a giant prolactinoma during pregnancy.
Khaldi S, Saad G, Elfekih H, Ben Abdelkrim A, Ach T, Kacem M, Chaieb M, Maaroufi A, Hasni Y, Ach K
Gynecol Endocrinol 2021 Sep;37(9):863-866. Epub 2021 Jun 14 doi: 10.1080/09513590.2021.1938527. PMID: 34124989
Metabolically healthy and unhealthy obesity in erectile dysfunction and male infertility.
Rastrelli G, Lotti F, Reisman Y, Sforza A, Maggi M, Corona G
Expert Rev Endocrinol Metab 2019 Sep;14(5):321-334. Epub 2019 Aug 29 doi: 10.1080/17446651.2019.1657827. PMID: 31464531
Long-term effects on sexual function and fertility after treatment of testicular cancer.
Hartmann JT, Albrecht C, Schmoll HJ, Kuczyk MA, Kollmannsberger C, Bokemeyer C
Br J Cancer 1999 May;80(5-6):801-7. doi: 10.1038/sj.bjc.6690424. PMID: 10360658Free PMC Article
Sexual and marital relationships after radiotherapy for seminoma.
Schover LR, Gonzales M, von Eschenbach AC
Urology 1986 Feb;27(2):117-23. doi: 10.1016/0090-4295(86)90367-5. PMID: 3946034

Clinical prediction guides

Transsphenoidal surgery for prolactinomas in male patients: a retrospective study.
Su WJ, Cai HC, Yang GC, He KJ, Wu HL, Yang YB, Tang HX, Yang LX, Deng CH
Asian J Androl 2023 Jan-Feb;25(1):113-118. doi: 10.4103/aja202233. PMID: 35645047Free PMC Article
Male Gonadal Function After Pediatric Hematopoietic Stem Cell Transplantation: A Systematic Review.
Mathiesen S, Andrés-Jensen L, Nielsen MM, Sørensen K, Ifversen M, Jahnukainen K, Juul A, Müller K
Transplant Cell Ther 2022 Aug;28(8):503.e1-503.e15. Epub 2022 May 26 doi: 10.1016/j.jtct.2022.05.036. PMID: 35644480
Nonalcoholic Fatty Liver Disease, Male Sexual Dysfunction, and Infertility: Common Links, Common Problems.
Hawksworth DJ, Burnett AL
Sex Med Rev 2020 Apr;8(2):274-285. Epub 2019 Mar 19 doi: 10.1016/j.sxmr.2019.01.002. PMID: 30898592
Metabolically healthy and unhealthy obesity in erectile dysfunction and male infertility.
Rastrelli G, Lotti F, Reisman Y, Sforza A, Maggi M, Corona G
Expert Rev Endocrinol Metab 2019 Sep;14(5):321-334. Epub 2019 Aug 29 doi: 10.1080/17446651.2019.1657827. PMID: 31464531
Sexual dysfunction in infertile women: A systematic review and meta-analysis.
Mendonça CR, Arruda JT, Noll M, Campoli PMO, Amaral WND
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:153-163. Epub 2017 Jun 7 doi: 10.1016/j.ejogrb.2017.06.013. PMID: 28628848

Recent systematic reviews

Male Gonadal Function After Pediatric Hematopoietic Stem Cell Transplantation: A Systematic Review.
Mathiesen S, Andrés-Jensen L, Nielsen MM, Sørensen K, Ifversen M, Jahnukainen K, Juul A, Müller K
Transplant Cell Ther 2022 Aug;28(8):503.e1-503.e15. Epub 2022 May 26 doi: 10.1016/j.jtct.2022.05.036. PMID: 35644480
Sexual dysfunction in infertile women: A systematic review and meta-analysis.
Mendonça CR, Arruda JT, Noll M, Campoli PMO, Amaral WND
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:153-163. Epub 2017 Jun 7 doi: 10.1016/j.ejogrb.2017.06.013. PMID: 28628848
A systematic review of randomized controlled trials examining the effectiveness of saffron (Crocus sativus L.) on psychological and behavioral outcomes.
Hausenblas HA, Heekin K, Mutchie HL, Anton S
J Integr Med 2015 Jul;13(4):231-40. doi: 10.1016/S2095-4964(15)60176-5. PMID: 26165367Free PMC Article
Urological complications following inguinal hernioplasty.
Gulino G, Antonucci M, Palermo G, Sasso F, Tienforti D, D'Addessi A, Bassi PF
Arch Ital Urol Androl 2012 Sep;84(3):105-10. PMID: 23210400

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