U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Systemic Arterial Hypertensive Disorder

MedGen UID:
761998
•Concept ID:
C3541293
•
Disease or Syndrome

Definition

Any condition resulting in systemically elevated blood pressure that is attributed to an arterial source. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSystemic Arterial Hypertensive Disorder

Professional guidelines

PubMed

State-of-the-art evidence in the treatment of systemic sclerosis.
Pope JE, Denton CP, Johnson SR, Fernandez-Codina A, Hudson M, Nevskaya T
Nat Rev Rheumatol 2023 Apr;19(4):212-226. Epub 2023 Feb 27 doi: 10.1038/s41584-023-00909-5. PMID: 36849541Free PMC Article
Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Konstam MA, Kiernan MS, Bernstein D, Bozkurt B, Jacob M, Kapur NK, Kociol RD, Lewis EF, Mehra MR, Pagani FD, Raval AN, Ward C; American Heart Association Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular Surgery and Anesthesia
Circulation 2018 May 15;137(20):e578-e622. Epub 2018 Apr 12 doi: 10.1161/CIR.0000000000000560. PMID: 29650544
Update of EULAR recommendations for the treatment of systemic sclerosis.
Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U; EUSTAR Coauthors
Ann Rheum Dis 2017 Aug;76(8):1327-1339. Epub 2016 Nov 9 doi: 10.1136/annrheumdis-2016-209909. PMID: 27941129

Recent clinical studies

Etiology

Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia.
Qu H, Khalil RA
Am J Physiol Heart Circ Physiol 2020 Sep 1;319(3):H661-H681. Epub 2020 Aug 7 doi: 10.1152/ajpheart.00202.2020. PMID: 32762557Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
The pathophysiology of chronic thromboembolic pulmonary hypertension.
Simonneau G, Torbicki A, Dorfmüller P, Kim N
Eur Respir Rev 2017 Mar 31;26(143) Epub 2017 Mar 29 doi: 10.1183/16000617.0112-2016. PMID: 28356405Free PMC Article
Renal Ultrasound (and Doppler Sonography) in Hypertension: An Update.
Boddi M
Adv Exp Med Biol 2017;956:191-208. doi: 10.1007/5584_2016_170. PMID: 27966109
Definitions and diagnosis of pulmonary hypertension.
Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, Langleben D, Manes A, Satoh T, Torres F, Wilkins MR, Badesch DB
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D42-50. doi: 10.1016/j.jacc.2013.10.032. PMID: 24355641

Diagnosis

BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
Cuthbertson I, Morrell NW, Caruso P
Circ Res 2023 Jan 6;132(1):109-126. Epub 2023 Jan 5 doi: 10.1161/CIRCRESAHA.122.321554. PMID: 36603064
The physiological basis of pulmonary arterial hypertension.
Naeije R, Richter MJ, Rubin LJ
Eur Respir J 2022 Jun;59(6) Epub 2022 Jun 16 doi: 10.1183/13993003.02334-2021. PMID: 34737219Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
Definitions and diagnosis of pulmonary hypertension.
Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, Langleben D, Manes A, Satoh T, Torres F, Wilkins MR, Badesch DB
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D42-50. doi: 10.1016/j.jacc.2013.10.032. PMID: 24355641
Pediatric pulmonary hypertension.
Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Schulze Neick I, Steinhorn RH, Beghetti M
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D117-26. doi: 10.1016/j.jacc.2013.10.028. PMID: 24355636

Therapy

Different exercise training modalities produce similar endothelial function improvements in individuals with prehypertension or hypertension: a randomized clinical trial Exercise, endothelium and blood pressure.
Pedralli ML, Marschner RA, Kollet DP, Neto SG, Eibel B, Tanaka H, Lehnen AM
Sci Rep 2020 May 6;10(1):7628. doi: 10.1038/s41598-020-64365-x. PMID: 32376984Free PMC Article
Sodium Intake and Hypertension.
Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G
Nutrients 2019 Aug 21;11(9) doi: 10.3390/nu11091970. PMID: 31438636Free PMC Article
Phosphodiesterase 5 inhibitors for pulmonary hypertension.
Barnes H, Brown Z, Burns A, Williams T
Cochrane Database Syst Rev 2019 Jan 31;1(1):CD012621. doi: 10.1002/14651858.CD012621.pub2. PMID: 30701543Free PMC Article
Microvascular injury and the kidney in hypertension.
Ruiz-Hurtado G, Ruilope LM
Hipertens Riesgo Vasc 2018 Jan-Mar;35(1):24-29. Epub 2017 Apr 18 doi: 10.1016/j.hipert.2017.03.002. PMID: 28431922
Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome.
Drager LF, Togeiro SM, Polotsky VY, Lorenzi-Filho G
J Am Coll Cardiol 2013 Aug 13;62(7):569-76. Epub 2013 Jun 12 doi: 10.1016/j.jacc.2013.05.045. PMID: 23770180Free PMC Article

Prognosis

Acute Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension: Clinical and Serial CT Pulmonary Angiographic Features.
An J, Nam Y, Cho H, Chang J, Kim DK, Lee KS
J Korean Med Sci 2022 Mar 14;37(10):e76. doi: 10.3346/jkms.2022.37.e76. PMID: 35289137Free PMC Article
Exertional dyspnoea in pulmonary arterial hypertension.
Dumitrescu D, Sitbon O, Weatherald J, Howard LS
Eur Respir Rev 2017 Sep 30;26(145) Epub 2017 Sep 6 doi: 10.1183/16000617.0039-2017. PMID: 28877974Free PMC Article
The pathophysiology of chronic thromboembolic pulmonary hypertension.
Simonneau G, Torbicki A, Dorfmüller P, Kim N
Eur Respir Rev 2017 Mar 31;26(143) Epub 2017 Mar 29 doi: 10.1183/16000617.0112-2016. PMID: 28356405Free PMC Article
Renal Ultrasound (and Doppler Sonography) in Hypertension: An Update.
Boddi M
Adv Exp Med Biol 2017;956:191-208. doi: 10.1007/5584_2016_170. PMID: 27966109
Pediatric pulmonary hypertension.
Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Schulze Neick I, Steinhorn RH, Beghetti M
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D117-26. doi: 10.1016/j.jacc.2013.10.028. PMID: 24355636

Clinical prediction guides

BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension.
Cuthbertson I, Morrell NW, Caruso P
Circ Res 2023 Jan 6;132(1):109-126. Epub 2023 Jan 5 doi: 10.1161/CIRCRESAHA.122.321554. PMID: 36603064
Acute Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension: Clinical and Serial CT Pulmonary Angiographic Features.
An J, Nam Y, Cho H, Chang J, Kim DK, Lee KS
J Korean Med Sci 2022 Mar 14;37(10):e76. doi: 10.3346/jkms.2022.37.e76. PMID: 35289137Free PMC Article
The pathophysiology of chronic thromboembolic pulmonary hypertension.
Simonneau G, Torbicki A, Dorfmüller P, Kim N
Eur Respir Rev 2017 Mar 31;26(143) Epub 2017 Mar 29 doi: 10.1183/16000617.0112-2016. PMID: 28356405Free PMC Article
Renal Ultrasound (and Doppler Sonography) in Hypertension: An Update.
Boddi M
Adv Exp Med Biol 2017;956:191-208. doi: 10.1007/5584_2016_170. PMID: 27966109
Definitions and diagnosis of pulmonary hypertension.
Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, Langleben D, Manes A, Satoh T, Torres F, Wilkins MR, Badesch DB
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D42-50. doi: 10.1016/j.jacc.2013.10.032. PMID: 24355641

Recent systematic reviews

Pregnancy in patients with systemic lupus erythematosus: a systematic review.
Zhang S, Han X, Liu W, Wen Q, Wang J
Arch Gynecol Obstet 2023 Jul;308(1):63-71. Epub 2022 Aug 1 doi: 10.1007/s00404-022-06718-7. PMID: 35913558
Impact of stress and hypertension on the cerebrovasculature.
Elsaid N, Saied A, Kandil H, Soliman A, Taher F, Hadi M, Giridharan G, Jennings R, Casanova M, Keynton R, El-Baz A
Front Biosci (Landmark Ed) 2021 Dec 30;26(12):1643-1652. doi: 10.52586/5057. PMID: 34994178
Cardiovascular Changes in Menopause.
Nair AR, Pillai AJ, Nair N
Curr Cardiol Rev 2021;17(4):e230421187681. doi: 10.2174/1573403X16666201106141811. PMID: 33155924Free PMC Article
Drug-associated pulmonary arterial hypertension.
McGee M, Whitehead N, Martin J, Collins N
Clin Toxicol (Phila) 2018 Sep;56(9):801-809. Epub 2018 Mar 6 doi: 10.1080/15563650.2018.1447119. PMID: 29508628
Update of EULAR recommendations for the treatment of systemic sclerosis.
Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U; EUSTAR Coauthors
Ann Rheum Dis 2017 Aug;76(8):1327-1339. Epub 2016 Nov 9 doi: 10.1136/annrheumdis-2016-209909. PMID: 27941129

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...