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In situ carcinoma

MedGen UID:
763
Concept ID:
C0007099
Neoplastic Process
Synonyms: Carcinoma in Situ; Carcinoma, Intraepithelial; Carcinoma, Preinvasive; Intraepithelial Carcinoma; Preinvasive Carcinoma
SNOMED CT: Carcinoma in situ (109355002); Cancer in situ (109355002); Non-invasive carcinoma (1187138006); Intraepithelial carcinoma (1187138006); Carcinoma in situ (1187138006)
 
Monarch Initiative: MONDO:0004647

Definition

A malignant epithelial neoplasm which is confined to the epithelial layer without evidence of further tissue invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIn situ carcinoma

Professional guidelines

PubMed

Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Trayes KP, Cokenakes SEH
Am Fam Physician 2021 Aug 1;104(2):171-178. PMID: 34383430
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Recent clinical studies

Etiology

Bandyopadhyay S, Bluth MH, Ali-Fehmi R
Clin Lab Med 2018 Jun;38(2):401-420. doi: 10.1016/j.cll.2018.02.006. PMID: 29776638
Kohn EC, Ivy SP
Am Soc Clin Oncol Educ Book 2017;37:443-448. doi: 10.1200/EDBK_174718. PMID: 28561656
Bandyopadhyay S, Ali-Fehmi R
Clin Lab Med 2013 Dec;33(4):891-909. doi: 10.1016/j.cll.2013.08.009. PMID: 24267194
Lantuéjoul S, Salameire D, Salon C, Brambilla E
Histopathology 2009 Jan;54(1):43-54. doi: 10.1111/j.1365-2559.2008.03182.x. PMID: 19187179
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560

Diagnosis

Li Z, Dabbs DJ
Pathobiology 2022;89(5):309-323. Epub 2022 Mar 4 doi: 10.1159/000521682. PMID: 35249034
Quinn CM, D'Arcy C, Wells C
Virchows Arch 2022 Jan;480(1):177-189. Epub 2021 Sep 18 doi: 10.1007/s00428-021-03185-4. PMID: 34537861Free PMC Article
Bandyopadhyay S, Bluth MH, Ali-Fehmi R
Clin Lab Med 2018 Jun;38(2):401-420. doi: 10.1016/j.cll.2018.02.006. PMID: 29776638
Rakha EA, Ellis IO
Pathology 2018 Jan;50(1):100-110. Epub 2017 Nov 26 doi: 10.1016/j.pathol.2017.10.005. PMID: 29179906
Hadziselimovic F
Urol Int 2016;96(3):249-54. Epub 2016 Jan 30 doi: 10.1159/000443741. PMID: 26824668

Therapy

Cramer P, Stockfleth E
Expert Opin Emerg Drugs 2020 Mar;25(1):49-58. Epub 2020 Feb 20 doi: 10.1080/14728214.2020.1730810. PMID: 32067498
Hadziselimovic F
Urol Int 2016;96(3):249-54. Epub 2016 Jan 30 doi: 10.1159/000443741. PMID: 26824668
Ahmed N, Abubaker K, Findlay J, Quinn M
J Cell Biochem 2013 Jan;114(1):21-34. doi: 10.1002/jcb.24317. PMID: 22887554
Horn LC, Meinel A, Handzel R, Einenkel J
Ann Diagn Pathol 2007 Aug;11(4):297-311. doi: 10.1016/j.anndiagpath.2007.05.002. PMID: 17630117
Stern JL, Lacey CG
Baillieres Clin Obstet Gynaecol 1987 Jun;1(2):277-92. doi: 10.1016/s0950-3552(87)80055-x. PMID: 3319336

Prognosis

Li Z, Dabbs DJ
Pathobiology 2022;89(5):309-323. Epub 2022 Mar 4 doi: 10.1159/000521682. PMID: 35249034
Rakha EA, Ellis IO
Pathology 2018 Jan;50(1):100-110. Epub 2017 Nov 26 doi: 10.1016/j.pathol.2017.10.005. PMID: 29179906
Kohn EC, Ivy SP
Am Soc Clin Oncol Educ Book 2017;37:443-448. doi: 10.1200/EDBK_174718. PMID: 28561656
Bandyopadhyay S, Ali-Fehmi R
Clin Lab Med 2013 Dec;33(4):891-909. doi: 10.1016/j.cll.2013.08.009. PMID: 24267194
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560

Clinical prediction guides

Li Z, Dabbs DJ
Pathobiology 2022;89(5):309-323. Epub 2022 Mar 4 doi: 10.1159/000521682. PMID: 35249034
Caziuc A, Andras D, Fagarasan V, Dindelegan GC
J BUON 2021 Sep-Oct;26(5):1970-1974. PMID: 34761607
Rakha EA, Ellis IO
Pathology 2018 Jan;50(1):100-110. Epub 2017 Nov 26 doi: 10.1016/j.pathol.2017.10.005. PMID: 29179906
Kohn EC, Ivy SP
Am Soc Clin Oncol Educ Book 2017;37:443-448. doi: 10.1200/EDBK_174718. PMID: 28561656
Bandyopadhyay S, Ali-Fehmi R
Clin Lab Med 2013 Dec;33(4):891-909. doi: 10.1016/j.cll.2013.08.009. PMID: 24267194

Recent systematic reviews

Mocellin S, Goodwin A, Pasquali S
Cochrane Database Syst Rev 2019 Apr 29;4(4):CD012191. doi: 10.1002/14651858.CD012191.pub2. PMID: 31032883Free PMC Article
Verschuur-Maes AH, van Deurzen CH, Monninkhof EM, van Diest PJ
Ann Surg 2012 Feb;255(2):259-65. doi: 10.1097/SLA.0b013e318233523f. PMID: 21989373

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