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Onycholysis of fingernails

MedGen UID:
765958
Concept ID:
C3553044
Finding
Synonym: Fingernail onycholysis
 
HPO: HP:0040039

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOnycholysis of fingernails

Conditions with this feature

Ectodermal dysplasia 9, hair/nail type
MedGen UID:
767041
Concept ID:
C3554127
Disease or Syndrome
Some ectodermal dysplasias are here classified as congenital disorders characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings. Ectodermal dysplasia of the hair/nail type is a rare congenital condition characterized by hypotrichosis and nail dystrophy without nonectodermal or other ectodermal manifestations. Hypotrichosis usually occurs after birth with varying degrees of severity, ranging from mild hair loss to complete atrichia, including the loss of scalp hair, beard, eyebrows, eyelashes, axillary hair, and pubic hair. Nail dystrophy affects all 20 digits by causing short fragile nails or spoon nails (koilonychia) (summary by Lin et al., 2012).

Professional guidelines

PubMed

Baran R, Richert B
Hand Surg Rehabil 2024 Apr;43S:101653. doi: 10.1016/j.hansur.2024.101653. PMID: 38879229
Lee DK, Lipner SR
Ann Med 2022 Dec;54(1):694-712. doi: 10.1080/07853890.2022.2044511. PMID: 35238267Free PMC Article
Filisio F, Busch S, Wickramage DJH, Hill R, Kabadi S, Van Pelt CL, Vlahovic TC
Clin Podiatr Med Surg 2021 Oct;38(4):521-527. doi: 10.1016/j.cpm.2021.06.001. PMID: 34538429

Recent clinical studies

Etiology

Wang S, Zhu J, Wang P, Dong J, Li Y, Shi D, Wang H, Huang X, Zhang X, Yu B, Yang Z, Chen R, Wang X, Li F, Bian K, Huo Y, Yu N, Li C, Xia X, Lu J, Li J, Lu Y, Xu Y, Ding Y, Li Y, Kang X, Li R
J Eur Acad Dermatol Venereol 2024 Mar;38(3):549-556. Epub 2023 Dec 15 doi: 10.1111/jdv.19684. PMID: 38100231
Reid CR, Charvat JM, Mcfarland SM, Norcross JR, Benson E, England S, Rajulu S
Hum Factors 2023 Sep;65(6):988-1000. Epub 2021 Dec 27 doi: 10.1177/00187208211062299. PMID: 34961336
Canal-García E, Bosch-Amate X, Belinchón I, Puig L
Actas Dermosifiliogr 2022 May;113(5):481-490. Epub 2022 Feb 2 doi: 10.1016/j.ad.2022.01.006. PMID: 35697407
Dinani N, George S
Clin Exp Dermatol 2019 Aug;44(6):599-605. Epub 2019 Feb 21 doi: 10.1111/ced.13929. PMID: 30793352
Shemer A, Daniel CR 3rd
Clin Dermatol 2013 Sep-Oct;31(5):578-86. doi: 10.1016/j.clindermatol.2013.06.015. PMID: 24079587

Diagnosis

Canal-García E, Bosch-Amate X, Belinchón I, Puig L
Actas Dermosifiliogr 2022 May;113(5):481-490. Epub 2022 Feb 2 doi: 10.1016/j.ad.2022.01.006. PMID: 35697407
Lee DK, Lipner SR
Ann Med 2022 Dec;54(1):694-712. doi: 10.1080/07853890.2022.2044511. PMID: 35238267Free PMC Article
Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Mello CDBF, Souza MDRE, Noriega LF, Chiacchio ND
An Bras Dermatol 2018 Sep-Oct;93(5):707-711. doi: 10.1590/abd1806-4841.20187908. PMID: 30156621Free PMC Article

Therapy

Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Dinani N, George S
Clin Exp Dermatol 2019 Aug;44(6):599-605. Epub 2019 Feb 21 doi: 10.1111/ced.13929. PMID: 30793352
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Baran R, Juhlin L
Photodermatol Photoimmunol Photomed 2002 Aug;18(4):202-7. doi: 10.1034/j.1600-0781.2002.00760.x. PMID: 12390677
Kechijian P
J Am Acad Dermatol 1985 Mar;12(3):552-60. doi: 10.1016/s0190-9622(85)70077-1. PMID: 3886720

Prognosis

Grover C, Jayasree P, Kaliyadan F
Int J Dermatol 2021 Jun;60(6):693-702. Epub 2020 Dec 17 doi: 10.1111/ijd.15358. PMID: 33332614
Chelidze K, Lipner SR
Int J Dermatol 2018 Jul;57(7):776-783. Epub 2018 Jan 10 doi: 10.1111/ijd.13866. PMID: 29318582
Baran R
Dermatology 2010;221 Suppl 1:1-5. Epub 2010 Aug 9 doi: 10.1159/000316169. PMID: 20733309
Sharquie IK, Al-Faham M, Karhoot JM, Sharquie KE, Al-Waiz MM, Al-Douri WS
Saudi Med J 2005 Sep;26(9):1439-41. PMID: 16155665
Lecha M, Effendy I, Feuilhade de Chauvin M, Di Chiacchio N, Baran R; Taskforce on Onychomycosis Education
J Eur Acad Dermatol Venereol 2005 Sep;19 Suppl 1:25-33. doi: 10.1111/j.1468-3083.2005.01284.x. PMID: 16120203

Clinical prediction guides

Grover C, Jayasree P, Kaliyadan F
Int J Dermatol 2021 Jun;60(6):693-702. Epub 2020 Dec 17 doi: 10.1111/ijd.15358. PMID: 33332614
Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Piraccini BM, Iorizzo M, Tosti A
Am J Clin Dermatol 2003;4(1):31-7. doi: 10.2165/00128071-200304010-00004. PMID: 12477371
Baran R, Juhlin L
Photodermatol Photoimmunol Photomed 2002 Aug;18(4):202-7. doi: 10.1034/j.1600-0781.2002.00760.x. PMID: 12390677

Recent systematic reviews

Rachadi H, Chiheb S
Int J Dermatol 2024 Aug;63(8):1013-1019. Epub 2024 Mar 22 doi: 10.1111/ijd.17138. PMID: 38520074
Golińska J, Sar-Pomian M, Rudnicka L
J Eur Acad Dermatol Venereol 2019 Apr;33(4):648-660. doi: 10.1111/jdv.15344. PMID: 30422349
Rouzaud M, Sevrain M, Villani AP, Barnetche T, Paul C, Richard MA, Jullien D, Misery L, Le Maître M, Aractingi S, Aubin F, Joly P, Cantagrel A, Ortonne JP, Beylot-Barry M
J Eur Acad Dermatol Venereol 2014 Aug;28 Suppl 5:17-26. doi: 10.1111/jdv.12562. PMID: 24985559

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