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Colorectal cancer, early onset

MedGen UID:
767686
•Concept ID:
C3554772
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Colorectal cancer, early onset

Professional guidelines

PubMed

Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.
Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, Kühn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, Møller P, Monahan KJ, Möslein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM; Associazione Italiana Familiarità Ereditarietà Tumori; Collaborative Group of the Americas on Inherited Gastrointestinal Cancer; European Hereditary Tumour Group, and the International Society for Gastrointestinal Hereditary Tumours
Clin Gastroenterol Hepatol 2023 Mar;21(3):581-603.e33. Epub 2022 Dec 20 doi: 10.1016/j.cgh.2022.12.006. PMID: 36549470
Trends, clinicopathological features, surgical treatment patterns and prognoses of early-onset versus late-onset colorectal cancer: A retrospective cohort study on 34067 patients managed from 2000 to 2021 in a Chinese tertiary center.
Gao XH, Li J, Liu LJ, Zheng NX, Zheng K, Mei Z, Bai CG, Zhang W
Int J Surg 2022 Aug;104:106780. Epub 2022 Jul 16 doi: 10.1016/j.ijsu.2022.106780. PMID: 35850466
An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer.
Burnett-Hartman AN, Lee JK, Demb J, Gupta S
Gastroenterology 2021 Mar;160(4):1041-1049. Epub 2021 Jan 5 doi: 10.1053/j.gastro.2020.12.068. PMID: 33417940Free PMC Article

Recent clinical studies

Etiology

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Screening and prevention of colorectal cancer.
Kanth P, Inadomi JM
BMJ 2021 Sep 15;374:n1855. doi: 10.1136/bmj.n1855. PMID: 34526356
An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer.
Burnett-Hartman AN, Lee JK, Demb J, Gupta S
Gastroenterology 2021 Mar;160(4):1041-1049. Epub 2021 Jan 5 doi: 10.1053/j.gastro.2020.12.068. PMID: 33417940Free PMC Article
Early-onset colorectal cancer in young individuals.
Mauri G, Sartore-Bianchi A, Russo AG, Marsoni S, Bardelli A, Siena S
Mol Oncol 2019 Feb;13(2):109-131. Epub 2018 Dec 22 doi: 10.1002/1878-0261.12417. PMID: 30520562Free PMC Article

Diagnosis

Increasing Incidence of Early-Onset Colorectal Cancer.
Sinicrope FA
N Engl J Med 2022 Apr 21;386(16):1547-1558. doi: 10.1056/NEJMra2200869. PMID: 35443109
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Screening and prevention of colorectal cancer.
Kanth P, Inadomi JM
BMJ 2021 Sep 15;374:n1855. doi: 10.1136/bmj.n1855. PMID: 34526356
An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer.
Burnett-Hartman AN, Lee JK, Demb J, Gupta S
Gastroenterology 2021 Mar;160(4):1041-1049. Epub 2021 Jan 5 doi: 10.1053/j.gastro.2020.12.068. PMID: 33417940Free PMC Article
Early-onset colorectal cancer in young individuals.
Mauri G, Sartore-Bianchi A, Russo AG, Marsoni S, Bardelli A, Siena S
Mol Oncol 2019 Feb;13(2):109-131. Epub 2018 Dec 22 doi: 10.1002/1878-0261.12417. PMID: 30520562Free PMC Article

Therapy

Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Rising incidence of early-onset colorectal cancer - a call to action.
Akimoto N, Ugai T, Zhong R, Hamada T, Fujiyoshi K, Giannakis M, Wu K, Cao Y, Ng K, Ogino S
Nat Rev Clin Oncol 2021 Apr;18(4):230-243. Epub 2020 Nov 20 doi: 10.1038/s41571-020-00445-1. PMID: 33219329Free PMC Article
Early-onset colorectal cancer: initial clues and current views.
Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG
Nat Rev Gastroenterol Hepatol 2020 Jun;17(6):352-364. Epub 2020 Feb 21 doi: 10.1038/s41575-019-0253-4. PMID: 32086499
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Keum N, Giovannucci E
Nat Rev Gastroenterol Hepatol 2019 Dec;16(12):713-732. Epub 2019 Aug 27 doi: 10.1038/s41575-019-0189-8. PMID: 31455888
Colorectal Cancer in the Young.
Patel SG, Ahnen DJ
Curr Gastroenterol Rep 2018 Mar 28;20(4):15. doi: 10.1007/s11894-018-0618-9. PMID: 29616330

Prognosis

Increasing Incidence of Early-Onset Colorectal Cancer.
Sinicrope FA
N Engl J Med 2022 Apr 21;386(16):1547-1558. doi: 10.1056/NEJMra2200869. PMID: 35443109
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Keum N, Giovannucci E
Nat Rev Gastroenterol Hepatol 2019 Dec;16(12):713-732. Epub 2019 Aug 27 doi: 10.1038/s41575-019-0189-8. PMID: 31455888
Early-onset colorectal cancer in young individuals.
Mauri G, Sartore-Bianchi A, Russo AG, Marsoni S, Bardelli A, Siena S
Mol Oncol 2019 Feb;13(2):109-131. Epub 2018 Dec 22 doi: 10.1002/1878-0261.12417. PMID: 30520562Free PMC Article

Clinical prediction guides

Young-onset colorectal cancer.
Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987
Integrated metagenomic and metabolomic analysis reveals distinct gut-microbiome-derived phenotypes in early-onset colorectal cancer.
Kong C, Liang L, Liu G, Du L, Yang Y, Liu J, Shi D, Li X, Ma Y
Gut 2023 Jun;72(6):1129-1142. Epub 2022 Aug 11 doi: 10.1136/gutjnl-2022-327156. PMID: 35953094
A comprehensive framework for early-onset colorectal cancer research.
Eng C, Jácome AA, Agarwal R, Hayat MH, Byndloss MX, Holowatyj AN, Bailey C, Lieu CH
Lancet Oncol 2022 Mar;23(3):e116-e128. Epub 2022 Jan 31 doi: 10.1016/S1470-2045(21)00588-X. PMID: 35090673
Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review.
REACCT Collaborative, Zaborowski AM, Abdile A, Adamina M, Aigner F, d'Allens L, Allmer C, Álvarez A, Anula R, Andric M, Atallah S, Bach S, Bala M, Barussaud M, Bausys A, Bebington B, Beggs A, Bellolio F, Bennett MR, Berdinskikh A, Bevan V, Biondo S, Bislenghi G, Bludau M, Boutall A, Brouwer N, Brown C, Bruns C, Buchanan DD, Buchwald P, Burger JWA, Burlov N, Campanelli M, Capdepont M, Carvello M, Chew HH, Christoforidis D, Clark D, Climent M, Cologne KG, Contreras T, Croner R, Daniels IR, Dapri G, Davies J, Delrio P, Denost Q, Deutsch M, Dias A, D'Hoore A, Drozdov E, Duek D, Dunlop M, Dziki A, Edmundson A, Efetov S, El-Hussuna A, Elliot B, Emile S, Espin E, Evans M, Faes S, Faiz O, Fleming F, Foppa C, Fowler G, Frasson M, Figueiredo N, Forgan T, Frizelle F, Gadaev S, Gellona J, Glyn T, Gong J, Goran B, Greenwood E, Guren MG, Guillon S, Gutlic I, Hahnloser D, Hampel H, Hanly A, Hasegawa H, Iversen LH, Hill A, Hill J, Hoch J, Hoffmeister M, Hompes R, Hurtado L, Iaquinandi F, Imbrasaite U, Islam R, Jafari MD, Kanemitsu Y, Karachun A, Karimuddin AA, Keller DS, Kelly J, Kennelly R, Khrykov G, Kocian P, Koh C, Kok N, Knight KA, Knol J, Kontovounisios C, Korner H, Krivokapic Z, Kronberger I, Kroon HM, Kryzauskas M, Kural S, Kusters M, Lakkis Z, Lankov T, Larson D, Lázár G, Lee KY, Lee SH, Lefèvre JH, Lepisto A, Lieu C, Loi L, Lynch C, Maillou-Martinaud H, Maroli A, Martin S, Martling A, Matzel KE, Mayol J, McDermott F, Meurette G, Millan M, Mitteregger M, Moiseenko A, Monson JRT, Morarasu S, Moritani K, Möslein G, Munini M, Nahas C, Nahas S, Negoi I, Novikova A, Ocares M, Okabayashi K, Olkina A, Oñate-Ocaña L, Otero J, Ozen C, Pace U, São Julião GP, Panaiotti L, Panis Y, Papamichael D, Park J, Patel S, Patrón Uriburu JC, Pera M, Perez RO, Petrov A, Pfeffer F, Phang PT, Poskus T, Pringle H, Proud D, Raguz I, Rama N, Rasheed S, Raval MJ, Rega D, Reissfelder C, Reyes Meneses JC, Ris F, Riss S, Rodriguez-Zentner H, Roxburgh CS, Saklani A, Salido AJ, Sammour T, Saraste D, Schneider M, Seishima R, Sekulic A, Seppala T, Sheahan K, Shine R, Shlomina A, Sica GS, Singnomklao T, Siragusa L, Smart N, Solis A, Spinelli A, Staiger RD, Stamos MJ, Steele S, Sunderland M, Tan KK, Tanis PJ, Tekkis P, Teklay B, Tengku S, Jiménez-Toscano M, Tsarkov P, Turina M, Ulrich A, Vailati BB, van Harten M, Verhoef C, Warrier S, Wexner S, de Wilt H, Weinberg BA, Wells C, Wolthuis A, Xynos E, You N, Zakharenko A, Zeballos J, Winter DC
JAMA Surg 2021 Sep 1;156(9):865-874. doi: 10.1001/jamasurg.2021.2380. PMID: 34190968
Early age onset colorectal cancer.
Patel SG, Murphy CC, Lieu CH, Hampel H
Adv Cancer Res 2021;151:1-37. Epub 2021 May 15 doi: 10.1016/bs.acr.2021.03.001. PMID: 34148611

Recent systematic reviews

Quality of life in early-onset colorectal cancer patients: systematic review.
Waddell O, Mclauchlan J, McCombie A, Glyn T, Frizelle F
BJS Open 2023 May 5;7(3) doi: 10.1093/bjsopen/zrad030. PMID: 37151082Free PMC Article
Vitamin D as a chemopreventive agent in colorectal neoplasms. A systematic review and meta-analysis of randomized controlled trials.
Emmanouilidou G, Kalopitas G, Bakaloudi DR, Karanika E, Theocharidou E, Germanidis G, Chourdakis M
Pharmacol Ther 2022 Sep;237:108252. Epub 2022 Aug 1 doi: 10.1016/j.pharmthera.2022.108252. PMID: 35926664
Impact of the COVID-19 Pandemic on Colorectal Cancer Screening: a Systematic Review.
Mazidimoradi A, Tiznobaik A, Salehiniya H
J Gastrointest Cancer 2022 Sep;53(3):730-744. Epub 2021 Aug 18 doi: 10.1007/s12029-021-00679-x. PMID: 34406626Free PMC Article
Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Systematic Review of Prevalence, Risk Factors, and Risk for Metachronous Advanced Neoplasia in Patients With Young-Onset Colorectal Adenoma.
Enwerem N, Cho MY, Demb J, Earles A, Heskett KM, Liu L, Singh S, Gupta S
Clin Gastroenterol Hepatol 2021 Apr;19(4):680-689.e12. Epub 2020 May 16 doi: 10.1016/j.cgh.2020.04.092. PMID: 32428708Free PMC Article

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