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Substance Adverse Event

MedGen UID:
768686
•Concept ID:
C3640046
•
Finding

Definition

An unexpected or dangerous reaction to a substance (e.g., food, environmental agent). (ACC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance Adverse Event

Professional guidelines

PubMed

Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial.
Raison CL, Sanacora G, Woolley J, Heinzerling K, Dunlop BW, Brown RT, Kakar R, Hassman M, Trivedi RP, Robison R, Gukasyan N, Nayak SM, Hu X, O'Donnell KC, Kelmendi B, Sloshower J, Penn AD, Bradley E, Kelly DF, Mletzko T, Nicholas CR, Hutson PR, Tarpley G, Utzinger M, Lenoch K, Warchol K, Gapasin T, Davis MC, Nelson-Douthit C, Wilson S, Brown C, Linton W, Ross S, Griffiths RR
JAMA 2023 Sep 5;330(9):843-853. doi: 10.1001/jama.2023.14530. PMID: 37651119Free PMC Article
Perioperative Anaphylaxis: Evaluation and Management.
Manian DV, Volcheck GW
Clin Rev Allergy Immunol 2022 Jun;62(3):383-399. Epub 2021 Jul 10 doi: 10.1007/s12016-021-08874-1. PMID: 34247332
Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence.
Krinzinger H, Hall CL, Groom MJ, Ansari MT, Banaschewski T, Buitelaar JK, Carucci S, Coghill D, Danckaerts M, Dittmann RW, Falissard B, Garas P, Inglis SK, Kovshoff H, Kochhar P, McCarthy S, Nagy P, Neubert A, Roberts S, Sayal K, Sonuga-Barke E, Wong ICK, Xia J, Zuddas A, Hollis C, Konrad K, Liddle EB; ADDUCE Consortium
Neurosci Biobehav Rev 2019 Dec;107:945-968. Epub 2019 Sep 20 doi: 10.1016/j.neubiorev.2019.09.023. PMID: 31545988

Recent clinical studies

Etiology

Mindfulness-based interventions for substance use disorders.
Goldberg SB, Pace B, Griskaitis M, Willutzki R, Skoetz N, Thoenes S, Zgierska AE, Rösner S
Cochrane Database Syst Rev 2021 Oct 20;10(10):CD011723. doi: 10.1002/14651858.CD011723.pub2. PMID: 34668188Free PMC Article
United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA).
Oketch-Rabah HA, Madden EF, Roe AL, Betz JM
Nutrients 2021 Aug 10;13(8) doi: 10.3390/nu13082742. PMID: 34444905Free PMC Article
Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial.
Grebely J, Dalgard O, Conway B, Cunningham EB, Bruggmann P, Hajarizadeh B, Amin J, Bruneau J, Hellard M, Litwin AH, Marks P, Quiene S, Siriragavan S, Applegate TL, Swan T, Byrne J, Lacalamita M, Dunlop A, Matthews GV, Powis J, Shaw D, Thurnheer MC, Weltman M, Kronborg I, Cooper C, Feld JJ, Fraser C, Dillon JF, Read P, Gane E, Dore GJ; SIMPLIFY Study Group
Lancet Gastroenterol Hepatol 2018 Mar;3(3):153-161. Epub 2018 Jan 6 doi: 10.1016/S2468-1253(17)30404-1. PMID: 29310928
Energy drinks and their adverse health effects: A systematic review of the current evidence.
Ali F, Rehman H, Babayan Z, Stapleton D, Joshi DD
Postgrad Med 2015 Apr;127(3):308-22. Epub 2015 Jan 6 doi: 10.1080/00325481.2015.1001712. PMID: 25560302
Atomoxetine: a review of its use in attention-deficit hyperactivity disorder in children and adolescents.
Garnock-Jones KP, Keating GM
Paediatr Drugs 2009;11(3):203-26. doi: 10.2165/00148581-200911030-00005. PMID: 19445548

Diagnosis

Perioperative Anaphylaxis: Evaluation and Management.
Manian DV, Volcheck GW
Clin Rev Allergy Immunol 2022 Jun;62(3):383-399. Epub 2021 Jul 10 doi: 10.1007/s12016-021-08874-1. PMID: 34247332
Mindfulness-based interventions for substance use disorders.
Goldberg SB, Pace B, Griskaitis M, Willutzki R, Skoetz N, Thoenes S, Zgierska AE, Rösner S
Cochrane Database Syst Rev 2021 Oct 20;10(10):CD011723. doi: 10.1002/14651858.CD011723.pub2. PMID: 34668188Free PMC Article
Withdrawal Symptoms after Serotonin-Noradrenaline Reuptake Inhibitor Discontinuation: Systematic Review.
Fava GA, Benasi G, Lucente M, Offidani E, Cosci F, Guidi J
Psychother Psychosom 2018;87(4):195-203. Epub 2018 Jul 17 doi: 10.1159/000491524. PMID: 30016772
Adverse childhood experiences and behavioral problems in middle childhood.
Hunt TKA, Slack KS, Berger LM
Child Abuse Negl 2017 May;67:391-402. Epub 2016 Nov 21 doi: 10.1016/j.chiabu.2016.11.005. PMID: 27884508Free PMC Article
Consequences of misdiagnosis: inaccurate treatment and poor patient outcomes in bipolar disorder.
Nasrallah HA
J Clin Psychiatry 2015 Oct;76(10):e1328. doi: 10.4088/JCP.14016tx2c. PMID: 26528666

Therapy

Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.
Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Mindfulness-based interventions for substance use disorders.
Goldberg SB, Pace B, Griskaitis M, Willutzki R, Skoetz N, Thoenes S, Zgierska AE, Rösner S
Cochrane Database Syst Rev 2021 Oct 20;10(10):CD011723. doi: 10.1002/14651858.CD011723.pub2. PMID: 34668188Free PMC Article
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P
Cochrane Database Syst Rev 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. PMID: 33075160Free PMC Article
Current use and abuse of anabolic steroids.
Reyes-Vallejo L
Actas Urol Esp (Engl Ed) 2020 Jun;44(5):309-313. Epub 2020 Feb 26 doi: 10.1016/j.acuro.2019.10.011. PMID: 32113828
Cannabis-based medicines for chronic neuropathic pain in adults.
Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W
Cochrane Database Syst Rev 2018 Mar 7;3(3):CD012182. doi: 10.1002/14651858.CD012182.pub2. PMID: 29513392Free PMC Article

Prognosis

Microplastics and Nanoplastics in Atheromas and Cardiovascular Events.
Marfella R, Prattichizzo F, Sardu C, Fulgenzi G, Graciotti L, Spadoni T, D'Onofrio N, Scisciola L, La Grotta R, Frigé C, Pellegrini V, Municinò M, Siniscalchi M, Spinetti F, Vigliotti G, Vecchione C, Carrizzo A, Accarino G, Squillante A, Spaziano G, Mirra D, Esposito R, Altieri S, Falco G, Fenti A, Galoppo S, Canzano S, Sasso FC, Matacchione G, Olivieri F, Ferraraccio F, Panarese I, Paolisso P, Barbato E, Lubritto C, Balestrieri ML, Mauro C, Caballero AE, Rajagopalan S, Ceriello A, D'Agostino B, Iovino P, Paolisso G
N Engl J Med 2024 Mar 7;390(10):900-910. doi: 10.1056/NEJMoa2309822. PMID: 38446676Free PMC Article
Borderline Personality Disorder: Clinical Guidelines for Treatment.
Stone MH
Psychodyn Psychiatry 2019 Spring;47(1):5-26. doi: 10.1521/pdps.2019.47.1.5. PMID: 30840560
Toxic stress and child refugees.
Murray JS
J Spec Pediatr Nurs 2018 Jan;23(1) Epub 2017 Nov 20 doi: 10.1111/jspn.12200. PMID: 29155486
Early adverse experience and substance addiction: dopamine, oxytocin, and glucocorticoid pathways.
Kim S, Kwok S, Mayes LC, Potenza MN, Rutherford HJV, Strathearn L
Ann N Y Acad Sci 2017 Apr;1394(1):74-91. Epub 2016 Aug 10 doi: 10.1111/nyas.13140. PMID: 27508337Free PMC Article
Drug induced pancreatitis.
Nitsche CJ, Jamieson N, Lerch MM, Mayerle JV
Best Pract Res Clin Gastroenterol 2010 Apr;24(2):143-55. doi: 10.1016/j.bpg.2010.02.002. PMID: 20227028

Clinical prediction guides

Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis.
Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
Creatine supplementation improves performance, but is it safe? Double-blind placebo-controlled study.
Almeida D, Colombini A, Machado M
J Sports Med Phys Fitness 2020 Jul;60(7):1034-1039. doi: 10.23736/S0022-4707.20.10437-7. PMID: 32597619
Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial.
Grebely J, Dalgard O, Conway B, Cunningham EB, Bruggmann P, Hajarizadeh B, Amin J, Bruneau J, Hellard M, Litwin AH, Marks P, Quiene S, Siriragavan S, Applegate TL, Swan T, Byrne J, Lacalamita M, Dunlop A, Matthews GV, Powis J, Shaw D, Thurnheer MC, Weltman M, Kronborg I, Cooper C, Feld JJ, Fraser C, Dillon JF, Read P, Gane E, Dore GJ; SIMPLIFY Study Group
Lancet Gastroenterol Hepatol 2018 Mar;3(3):153-161. Epub 2018 Jan 6 doi: 10.1016/S2468-1253(17)30404-1. PMID: 29310928
Associations Between Adverse Childhood Experiences, High-Risk Behaviors, and Morbidity in Adulthood.
Campbell JA, Walker RJ, Egede LE
Am J Prev Med 2016 Mar;50(3):344-352. Epub 2015 Oct 21 doi: 10.1016/j.amepre.2015.07.022. PMID: 26474668Free PMC Article
Atomoxetine: a review of its use in attention-deficit hyperactivity disorder in children and adolescents.
Garnock-Jones KP, Keating GM
Paediatr Drugs 2009;11(3):203-26. doi: 10.2165/00148581-200911030-00005. PMID: 19445548

Recent systematic reviews

Comparative efficacy and tolerability of pharmacological interventions for acute bipolar depression in adults: a systematic review and network meta-analysis.
Yildiz A, Siafis S, Mavridis D, Vieta E, Leucht S
Lancet Psychiatry 2023 Sep;10(9):693-705. doi: 10.1016/S2215-0366(23)00199-2. PMID: 37595997
Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.
Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P
Cochrane Database Syst Rev 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. PMID: 33075160Free PMC Article
Cannabis-based medicines for chronic neuropathic pain in adults.
Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W
Cochrane Database Syst Rev 2018 Mar 7;3(3):CD012182. doi: 10.1002/14651858.CD012182.pub2. PMID: 29513392Free PMC Article
The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis.
Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, Jones L, Dunne MP
Lancet Public Health 2017 Aug;2(8):e356-e366. Epub 2017 Jul 31 doi: 10.1016/S2468-2667(17)30118-4. PMID: 29253477

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