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Epinephrine-Secreting

MedGen UID:
770308
•Concept ID:
C3641668
•
Finding
Synonym: Epinephrine Secreting

Definition

A finding indicating that an excess amount of epinephrine is secreted by a tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpinephrine-Secreting

Recent clinical studies

Etiology

Genetics and biology of pheochromocytoma.
Mannelli M, Simi L, Gaglianò MS, Opocher G, Ercolino T, Becherini L, Parenti G
Exp Clin Endocrinol Diabetes 2007 Mar;115(3):160-5. doi: 10.1055/s-2007-970407. PMID: 17427103
Pheochromocytomas: tendency to degenerate and cause paroxysmal hypertension.
Ito Y, Obara T, Yamashita T, Kanbe M, Iihara M
World J Surg 1996 Sep;20(7):923-6; discussion 927. doi: 10.1007/s002689900140. PMID: 8678972
Overnight excretion of urinary catecholamines and metabolites in the detection of pheochromocytoma.
Peaston RT, Lennard TW, Lai LC
J Clin Endocrinol Metab 1996 Apr;81(4):1378-84. doi: 10.1210/jcem.81.4.8636337. PMID: 8636337
Quantitation of iodine-123 MIBG uptake by normal adrenal medulla in hypertensive patients.
Bomanji J, Flatman WD, Horne T, Fettich J, Britton KE, Ross G, Besser GM
J Nucl Med 1987 Mar;28(3):319-24. PMID: 3819850
Use of labetalol during anesthesia for pheochromocytoma removal.
Van Stratum M, Levarlet M, Lambilliotte JP, Lignian H, de Rood M
Acta Anaesthesiol Belg 1983 Dec;34(4):233-40. PMID: 6673473

Diagnosis

Cardiovascular complications in patients with pheochromocytoma: a mini-review.
Galetta F, Franzoni F, Bernini G, Poupak F, Carpi A, Cini G, Tocchini L, Antonelli A, Santoro G
Biomed Pharmacother 2010 Sep;64(7):505-9. Epub 2009 Nov 17 doi: 10.1016/j.biopha.2009.09.014. PMID: 20580187
Epinephrine-secreting cystic pheochromocytoma presenting with an incidental adrenal mass: a case report and a review of the literature.
Erem C, Kocak M, Onder Ersoz H, Ersoz S, Yucel Y
Endocrine 2005 Nov;28(2):225-30. doi: 10.1385/endo:28:2:225. PMID: 16388097
Dopamine-secreting pheochromocytomas: in search of a syndrome.
Dubois LA, Gray DK
World J Surg 2005 Jul;29(7):909-13. doi: 10.1007/s00268-005-7860-7. PMID: 15951922
Overnight excretion of urinary catecholamines and metabolites in the detection of pheochromocytoma.
Peaston RT, Lennard TW, Lai LC
J Clin Endocrinol Metab 1996 Apr;81(4):1378-84. doi: 10.1210/jcem.81.4.8636337. PMID: 8636337
Biochemical diagnosis of pheochromocytoma by simultaneous measurement of urinary excretion of epinephrine and norepinephrine.
Smythe GA, Edwards G, Graham P, Lazarus L
Clin Chem 1992 Apr;38(4):486-92. PMID: 1568311

Therapy

Use of labetalol during anesthesia for pheochromocytoma removal.
Van Stratum M, Levarlet M, Lambilliotte JP, Lignian H, de Rood M
Acta Anaesthesiol Belg 1983 Dec;34(4):233-40. PMID: 6673473
Norepinephrine and epinephrine secretion from a clinically epinephrine-secreting pheochromocytoma.
Aronoff SL, Passamani E, Borowsky BA, Weiss AN, Roberts R, Cryer PE
Am J Med 1980 Aug;69(2):321-4. doi: 10.1016/0002-9343(80)90392-7. PMID: 6105823
Norepinephrine-secreting tumor of the organ of Zuckerkandl. Response to propranolol alone.
Newsome HH Jr, Weir GC, Daniel TM
JAMA 1979 Aug 10;242(6):540-2. PMID: 448987

Prognosis

Pseudohypoxia in paraganglioma and pheochromocytoma is associated with an immunosuppressive phenotype.
Celada L, Cubiella T, San-Juan-Guardado J, Gutiérrez G, Beiguela B, Rodriguez R, Poch M, Astudillo A, Grijalba A, Sánchez-Sobrino P, Tous M, Navarro E, Serrano T, Paja M, Valdés N, Chiara MD
J Pathol 2023 Jan;259(1):103-114. Epub 2022 Dec 1 doi: 10.1002/path.6026. PMID: 36314599Free PMC Article
Cardiac failure due to epinephrine-secreting pheochromocytoma: clinical, laboratory and pathological findings in a sudden death.
D'Errico S, Pomara C, Riezzo I, Neri M, Turillazzi E, Fineschi V
Forensic Sci Int 2009 May 30;187(1-3):e13-7. Epub 2009 Mar 3 doi: 10.1016/j.forsciint.2009.01.021. PMID: 19261400
Dopamine-secreting pheochromocytomas: in search of a syndrome.
Dubois LA, Gray DK
World J Surg 2005 Jul;29(7):909-13. doi: 10.1007/s00268-005-7860-7. PMID: 15951922

Clinical prediction guides

Genetics and biology of pheochromocytoma.
Mannelli M, Simi L, Gaglianò MS, Opocher G, Ercolino T, Becherini L, Parenti G
Exp Clin Endocrinol Diabetes 2007 Mar;115(3):160-5. doi: 10.1055/s-2007-970407. PMID: 17427103
Quantitation of iodine-123 MIBG uptake by normal adrenal medulla in hypertensive patients.
Bomanji J, Flatman WD, Horne T, Fettich J, Britton KE, Ross G, Besser GM
J Nucl Med 1987 Mar;28(3):319-24. PMID: 3819850

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