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Cramp

MedGen UID:
7749
Concept ID:
C0026821
Sign or Symptom
Synonyms: Cramp, Muscle; Cramp, Muscular; Cramps; Cramps, Muscle; Cramps, Muscular; Muscle Cramp; Muscle Cramps; Muscular Cramp; Muscular Cramps
SNOMED CT: Muscle cramps (55300003); Cramp (55300003); Cramp in muscle (55300003); Muscle cramp (55300003)

Definition

A sustained, sudden and involuntary contraction of a muscle or group of muscles. [from NCI]

Professional guidelines

PubMed

Dijkstra JN, Boon E, Kruijt N, Brusse E, Ramdas S, Jungbluth H, van Engelen BGM, Walters J, Voermans NC
Pract Neurol 2023 Feb;23(1):23-34. Epub 2022 Dec 15 doi: 10.1136/pn-2022-003574. PMID: 36522175
Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K
J Gastroenterol 2021 Jul;56(7):593-619. Epub 2021 Jul 7 doi: 10.1007/s00535-021-01788-x. PMID: 34231046Free PMC Article
Swash M, Czesnik D, de Carvalho M
Eur J Neurol 2019 Feb;26(2):214-221. Epub 2018 Sep 19 doi: 10.1111/ene.13799. PMID: 30168894

Recent clinical studies

Etiology

Miller KC, McDermott BP, Yeargin SW, Fiol A, Schwellnus MP
J Athl Train 2022 Jan 1;57(1):5-15. doi: 10.4085/1062-6050-0696.20. PMID: 34185846Free PMC Article
Garrison SR, Korownyk CS, Kolber MR, Allan GM, Musini VM, Sekhon RK, Dugré N
Cochrane Database Syst Rev 2020 Sep 21;9(9):CD009402. doi: 10.1002/14651858.CD009402.pub3. PMID: 32956536Free PMC Article
Maughan RJ, Shirreffs SM
Sports Med 2019 Dec;49(Suppl 2):115-124. doi: 10.1007/s40279-019-01162-1. PMID: 31696455Free PMC Article
Sandoval Y, Bell MR, Gulati R
Circ Cardiovasc Interv 2019 Nov;12(11):e007386. Epub 2019 Nov 1 doi: 10.1161/CIRCINTERVENTIONS.119.007386. PMID: 31672030
Filippakis A, Jara J, Ventura N, Scala S, Scopa C, Ruthazer R, Karakis I, Srinivasan J, Russell JA, Ho DT
Muscle Nerve 2018 Dec;58(6):852-854. Epub 2018 Sep 11 doi: 10.1002/mus.26193. PMID: 30028521

Diagnosis

Dijkstra JN, Boon E, Kruijt N, Brusse E, Ramdas S, Jungbluth H, van Engelen BGM, Walters J, Voermans NC
Pract Neurol 2023 Feb;23(1):23-34. Epub 2022 Dec 15 doi: 10.1136/pn-2022-003574. PMID: 36522175
Comperat L, Pegat A, Honnorat J, Joubert B
Curr Opin Neurol 2022 Oct 1;35(5):597-603. Epub 2022 Aug 19 doi: 10.1097/WCO.0000000000001104. PMID: 35989569
De Wel B, Claeys KG
Curr Opin Neurol 2021 Oct 1;34(5):714-720. doi: 10.1097/WCO.0000000000000963. PMID: 34914668
Ng L, Khan F, Young CA, Galea M
Cochrane Database Syst Rev 2017 Jan 10;1(1):CD011776. doi: 10.1002/14651858.CD011776.pub2. PMID: 28072907Free PMC Article
Goldman JG
Toxicon 2015 Dec 1;107(Pt A):98-104. Epub 2015 Sep 21 doi: 10.1016/j.toxicon.2015.09.024. PMID: 26391286

Therapy

Tapper EB, Parikh ND
JAMA 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031Free PMC Article
Garrison SR, Korownyk CS, Kolber MR, Allan GM, Musini VM, Sekhon RK, Dugré N
Cochrane Database Syst Rev 2020 Sep 21;9(9):CD009402. doi: 10.1002/14651858.CD009402.pub3. PMID: 32956536Free PMC Article
Qu H, Guo M, Chai H, Wang WT, Gao ZY, Shi DZ
J Am Heart Assoc 2018 Oct 2;7(19):e009835. doi: 10.1161/JAHA.118.009835. PMID: 30371340Free PMC Article
Young G
BMJ Clin Evid 2015 May 13;2015 PMID: 25970567Free PMC Article
Cramp F, Byron-Daniel J
Cochrane Database Syst Rev 2012 Nov 14;11(11):CD006145. doi: 10.1002/14651858.CD006145.pub3. PMID: 23152233Free PMC Article

Prognosis

Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K
J Gastroenterol 2021 Jul;56(7):593-619. Epub 2021 Jul 7 doi: 10.1007/s00535-021-01788-x. PMID: 34231046Free PMC Article
Cordell HJ, Fryett JJ, Ueno K, Darlay R, Aiba Y, Hitomi Y, Kawashima M, Nishida N, Khor SS, Gervais O, Kawai Y, Nagasaki M, Tokunaga K, Tang R, Shi Y, Li Z, Juran BD, Atkinson EJ, Gerussi A, Carbone M, Asselta R, Cheung A, de Andrade M, Baras A, Horowitz J, Ferreira MAR, Sun D, Jones DE, Flack S, Spicer A, Mulcahy VL, Byan J, Han Y, Sandford RN, Lazaridis KN, Amos CI, Hirschfield GM, Seldin MF, Invernizzi P, Siminovitch KA, Ma X, Nakamura M, Mells GF; PBC Consortia; Canadian PBC Consortium; Chinese PBC Consortium; Italian PBC Study Group; Japan-PBC-GWAS Consortium; US PBC Consortium; UK-PBC Consortium
J Hepatol 2021 Sep;75(3):572-581. Epub 2021 May 23 doi: 10.1016/j.jhep.2021.04.055. PMID: 34033851Free PMC Article
RECOVERY Collaborative Group
Lancet 2021 May 1;397(10285):1637-1645. doi: 10.1016/S0140-6736(21)00676-0. PMID: 33933206Free PMC Article
Sandoval Y, Bell MR, Gulati R
Circ Cardiovasc Interv 2019 Nov;12(11):e007386. Epub 2019 Nov 1 doi: 10.1161/CIRCINTERVENTIONS.119.007386. PMID: 31672030
Filippakis A, Jara J, Ventura N, Scala S, Scopa C, Ruthazer R, Karakis I, Srinivasan J, Russell JA, Ho DT
Muscle Nerve 2018 Dec;58(6):852-854. Epub 2018 Sep 11 doi: 10.1002/mus.26193. PMID: 30028521

Clinical prediction guides

Tapper EB, Parikh ND
JAMA 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031Free PMC Article
Tapper EB, Salim N, Baki J, Zhao Z, Sundaram V, Patwardhan V, Nikirk SJ
Am J Gastroenterol 2022 Jun 1;117(6):895-901. Epub 2022 Apr 13 doi: 10.14309/ajg.0000000000001781. PMID: 35416793
Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K
J Gastroenterol 2021 Jul;56(7):593-619. Epub 2021 Jul 7 doi: 10.1007/s00535-021-01788-x. PMID: 34231046Free PMC Article
Qu H, Guo M, Chai H, Wang WT, Gao ZY, Shi DZ
J Am Heart Assoc 2018 Oct 2;7(19):e009835. doi: 10.1161/JAHA.118.009835. PMID: 30371340Free PMC Article
Cramp F, Byron-Daniel J
Cochrane Database Syst Rev 2012 Nov 14;11(11):CD006145. doi: 10.1002/14651858.CD006145.pub3. PMID: 23152233Free PMC Article

Recent systematic reviews

Johnson MI, Paley CA, Jones G, Mulvey MR, Wittkopf PG
BMJ Open 2022 Feb 10;12(2):e051073. doi: 10.1136/bmjopen-2021-051073. PMID: 35144946Free PMC Article
Garrison SR, Korownyk CS, Kolber MR, Allan GM, Musini VM, Sekhon RK, Dugré N
Cochrane Database Syst Rev 2020 Sep 21;9(9):CD009402. doi: 10.1002/14651858.CD009402.pub3. PMID: 32956536Free PMC Article
Ng L, Khan F, Young CA, Galea M
Cochrane Database Syst Rev 2017 Jan 10;1(1):CD011776. doi: 10.1002/14651858.CD011776.pub2. PMID: 28072907Free PMC Article
Young G
BMJ Clin Evid 2015 May 13;2015 PMID: 25970567Free PMC Article
Cramp F, Byron-Daniel J
Cochrane Database Syst Rev 2012 Nov 14;11(11):CD006145. doi: 10.1002/14651858.CD006145.pub3. PMID: 23152233Free PMC Article

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