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Multiple chronic diseases

MedGen UID:
781391
Concept ID:
C3266262
Disease or Syndrome
Synonyms: Chronic Conditions, Multiple; Chronic Illnesses, Multiple; Multiple Chronic Conditions; Multiple Chronic Health Conditions; Multiple Chronic Illnesses; Multiple Chronic Medical Conditions
SNOMED CT: Multiple chronic diseases (2081000124103)

Definition

Two or more concurrent chronic physical, mental, or behavioral health problems in an individual. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple chronic diseases

Professional guidelines

PubMed

Stober MJ, Hager K, Rinker G
Home Healthc Now 2022 May-Jun 01;40(3):159-166. doi: 10.1097/NHH.0000000000001076. PMID: 35510971
Croci S, D'Apolito LI, Gasperi V, Catani MV, Savini I
Nutrients 2021 Apr 21;13(5) doi: 10.3390/nu13051389. PMID: 33919016Free PMC Article
Warsi A, Wang PS, LaValley MP, Avorn J, Solomon DH
Arch Intern Med 2004 Aug 9-23;164(15):1641-9. doi: 10.1001/archinte.164.15.1641. PMID: 15302634

Recent clinical studies

Etiology

Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Hustedde C
Prim Care 2021 Sep;48(3):493-504. Epub 2021 Jul 10 doi: 10.1016/j.pop.2021.05.005. PMID: 34311853
Ferrucci L, Gonzalez-Freire M, Fabbri E, Simonsick E, Tanaka T, Moore Z, Salimi S, Sierra F, de Cabo R
Aging Cell 2020 Feb;19(2):e13080. Epub 2019 Dec 12 doi: 10.1111/acel.13080. PMID: 31833194Free PMC Article
Tosti V, Bertozzi B, Fontana L
J Gerontol A Biol Sci Med Sci 2018 Mar 2;73(3):318-326. doi: 10.1093/gerona/glx227. PMID: 29244059Free PMC Article
Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, Meinow B, Fratiglioni L
Ageing Res Rev 2011 Sep;10(4):430-9. Epub 2011 Mar 23 doi: 10.1016/j.arr.2011.03.003. PMID: 21402176

Diagnosis

Chuang YN, Chen CC, Wang CJ, Chang YS, Liu YH
Psychogeriatrics 2023 Mar;23(2):337-344. Epub 2023 Jan 30 doi: 10.1111/psyg.12936. PMID: 36717278
Hustedde C
Prim Care 2021 Sep;48(3):493-504. Epub 2021 Jul 10 doi: 10.1016/j.pop.2021.05.005. PMID: 34311853
Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Zhu Y, Tchkonia T, Kirkland JL
EBioMedicine 2019 Sep;47:446-456. Epub 2019 Sep 18 doi: 10.1016/j.ebiom.2019.08.069. PMID: 31542391Free PMC Article
Jaul E, Barron J, Rosenzweig JP, Menczel J
BMC Geriatr 2018 Dec 11;18(1):305. doi: 10.1186/s12877-018-0997-7. PMID: 30537947Free PMC Article
Suls J, Green PA, Davidson KW
Psychosom Med 2016 Apr;78(3):281-9. doi: 10.1097/PSY.0000000000000294. PMID: 26867072Free PMC Article

Therapy

Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Ferrucci L, Gonzalez-Freire M, Fabbri E, Simonsick E, Tanaka T, Moore Z, Salimi S, Sierra F, de Cabo R
Aging Cell 2020 Feb;19(2):e13080. Epub 2019 Dec 12 doi: 10.1111/acel.13080. PMID: 31833194Free PMC Article
Lim BG, Lee IO
Korean J Anesthesiol 2020 Feb;73(1):8-29. Epub 2019 Oct 22 doi: 10.4097/kja.19391. PMID: 31636241Free PMC Article
Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Zhu Y, Tchkonia T, Kirkland JL
EBioMedicine 2019 Sep;47:446-456. Epub 2019 Sep 18 doi: 10.1016/j.ebiom.2019.08.069. PMID: 31542391Free PMC Article
Tosti V, Bertozzi B, Fontana L
J Gerontol A Biol Sci Med Sci 2018 Mar 2;73(3):318-326. doi: 10.1093/gerona/glx227. PMID: 29244059Free PMC Article

Prognosis

Li S, Xiao X, Zhang X
Nutrients 2023 Jun 2;15(11) doi: 10.3390/nu15112609. PMID: 37299572Free PMC Article
Watanabe K, Wilmanski T, Diener C, Earls JC, Zimmer A, Lincoln B, Hadlock JJ, Lovejoy JC, Gibbons SM, Magis AT, Hood L, Price ND, Rappaport N
Nat Med 2023 Apr;29(4):996-1008. Epub 2023 Mar 20 doi: 10.1038/s41591-023-02248-0. PMID: 36941332Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Meyer EJ, Wittert G
Asian J Androl 2018 Mar-Apr;20(2):115-119. doi: 10.4103/aja.aja_70_17. PMID: 29384142Free PMC Article
Snyder JM, Ward JM, Treuting PM
Vet Pathol 2016 Mar;53(2):233-43. Epub 2015 Oct 27 doi: 10.1177/0300985815610391. PMID: 26508696

Clinical prediction guides

Watanabe K, Wilmanski T, Diener C, Earls JC, Zimmer A, Lincoln B, Hadlock JJ, Lovejoy JC, Gibbons SM, Magis AT, Hood L, Price ND, Rappaport N
Nat Med 2023 Apr;29(4):996-1008. Epub 2023 Mar 20 doi: 10.1038/s41591-023-02248-0. PMID: 36941332Free PMC Article
Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Stober MJ, Hager K, Rinker G
Home Healthc Now 2022 May-Jun 01;40(3):159-166. doi: 10.1097/NHH.0000000000001076. PMID: 35510971
Liu D, Meng X, Tian Q, Cao W, Fan X, Wu L, Song M, Meng Q, Wang W, Wang Y
Adv Nutr 2022 Aug 1;13(4):1044-1062. doi: 10.1093/advances/nmab142. PMID: 34999745Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article

Recent systematic reviews

Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Palmu J, Lahti L, Niiranen T
Int J Environ Res Public Health 2021 Jan 30;18(3) doi: 10.3390/ijerph18031248. PMID: 33561095Free PMC Article
Xu X, Mishra GD, Jones M
Ageing Res Rev 2017 Aug;37:53-68. Epub 2017 May 13 doi: 10.1016/j.arr.2017.05.003. PMID: 28511964
Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, Meinow B, Fratiglioni L
Ageing Res Rev 2011 Sep;10(4):430-9. Epub 2011 Mar 23 doi: 10.1016/j.arr.2011.03.003. PMID: 21402176

Supplemental Content

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    Practice guidelines

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    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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