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Multiple chronic diseases

MedGen UID:
781391
Concept ID:
C3266262
Disease or Syndrome
Synonyms: Chronic Conditions, Multiple; Chronic Illnesses, Multiple; Multiple Chronic Conditions; Multiple Chronic Health Conditions; Multiple Chronic Illnesses; Multiple Chronic Medical Conditions
SNOMED CT: Multiple chronic diseases (2081000124103)

Definition

Two or more concurrent chronic physical, mental, or behavioral health problems in an individual. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple chronic diseases

Professional guidelines

PubMed

van Onna M, Boonen A
Nat Rev Rheumatol 2022 Jun;18(6):326-334. Epub 2022 Mar 21 doi: 10.1038/s41584-022-00768-6. PMID: 35314796
Croci S, D'Apolito LI, Gasperi V, Catani MV, Savini I
Nutrients 2021 Apr 21;13(5) doi: 10.3390/nu13051389. PMID: 33919016Free PMC Article
Kang E, Kim S, Rhee YE, Lee J, Yun YH
Psychol Health Med 2021 Sep;26(8):1031-1043. Epub 2020 Oct 23 doi: 10.1080/13548506.2020.1838585. PMID: 33095059

Recent clinical studies

Etiology

Liu D, Meng X, Tian Q, Cao W, Fan X, Wu L, Song M, Meng Q, Wang W, Wang Y
Adv Nutr 2022 Aug 1;13(4):1044-1062. doi: 10.1093/advances/nmab142. PMID: 34999745Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Hustedde C
Prim Care 2021 Sep;48(3):493-504. Epub 2021 Jul 10 doi: 10.1016/j.pop.2021.05.005. PMID: 34311853
Jaul E, Barron J, Rosenzweig JP, Menczel J
BMC Geriatr 2018 Dec 11;18(1):305. doi: 10.1186/s12877-018-0997-7. PMID: 30537947Free PMC Article
Tosti V, Bertozzi B, Fontana L
J Gerontol A Biol Sci Med Sci 2018 Mar 2;73(3):318-326. doi: 10.1093/gerona/glx227. PMID: 29244059Free PMC Article

Diagnosis

Shang X, Zhang X, Huang Y, Zhu Z, Zhang X, Liu S, Liu J, Tang S, Wang W, Yu H, Ge Z, He M
BMC Med 2022 May 27;20(1):185. doi: 10.1186/s12916-022-02384-3. PMID: 35619136Free PMC Article
Hustedde C
Prim Care 2021 Sep;48(3):493-504. Epub 2021 Jul 10 doi: 10.1016/j.pop.2021.05.005. PMID: 34311853
Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Zhu Y, Tchkonia T, Kirkland JL
EBioMedicine 2019 Sep;47:446-456. Epub 2019 Sep 18 doi: 10.1016/j.ebiom.2019.08.069. PMID: 31542391Free PMC Article
Jaul E, Barron J, Rosenzweig JP, Menczel J
BMC Geriatr 2018 Dec 11;18(1):305. doi: 10.1186/s12877-018-0997-7. PMID: 30537947Free PMC Article
Cantarero-Prieto D, Pascual-Sáez M, Blázquez-Fernández C
PLoS One 2018;13(10):e0205062. Epub 2018 Oct 24 doi: 10.1371/journal.pone.0205062. PMID: 30356322Free PMC Article

Therapy

Liu D, Meng X, Tian Q, Cao W, Fan X, Wu L, Song M, Meng Q, Wang W, Wang Y
Adv Nutr 2022 Aug 1;13(4):1044-1062. doi: 10.1093/advances/nmab142. PMID: 34999745Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Lim BG, Lee IO
Korean J Anesthesiol 2020 Feb;73(1):8-29. Epub 2019 Oct 22 doi: 10.4097/kja.19391. PMID: 31636241Free PMC Article
Tosti V, Bertozzi B, Fontana L
J Gerontol A Biol Sci Med Sci 2018 Mar 2;73(3):318-326. doi: 10.1093/gerona/glx227. PMID: 29244059Free PMC Article
Kunnumakkara AB, Bordoloi D, Padmavathi G, Monisha J, Roy NK, Prasad S, Aggarwal BB
Br J Pharmacol 2017 Jun;174(11):1325-1348. Epub 2016 Oct 21 doi: 10.1111/bph.13621. PMID: 27638428Free PMC Article

Prognosis

Wu D, Gao X, Shi Y, Wang H, Wang W, Li Y, Zheng Z
Int J Environ Res Public Health 2022 Oct 20;19(20) doi: 10.3390/ijerph192013616. PMID: 36294194Free PMC Article
Shang X, Zhang X, Huang Y, Zhu Z, Zhang X, Liu S, Liu J, Tang S, Wang W, Yu H, Ge Z, He M
BMC Med 2022 May 27;20(1):185. doi: 10.1186/s12916-022-02384-3. PMID: 35619136Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Kang E, Kim S, Rhee YE, Lee J, Yun YH
Psychol Health Med 2021 Sep;26(8):1031-1043. Epub 2020 Oct 23 doi: 10.1080/13548506.2020.1838585. PMID: 33095059
Hang D, Zeleznik OA, He X, Guasch-Ferre M, Jiang X, Li J, Liang L, Eliassen AH, Clish CB, Chan AT, Hu Z, Shen H, Wilson KM, Mucci LA, Sun Q, Hu FB, Willett WC, Giovannucci EL, Song M
Diabetes Care 2020 Oct;43(10):2588-2596. Epub 2020 Aug 11 doi: 10.2337/dc20-0800. PMID: 32788283Free PMC Article

Clinical prediction guides

Wu D, Gao X, Shi Y, Wang H, Wang W, Li Y, Zheng Z
Int J Environ Res Public Health 2022 Oct 20;19(20) doi: 10.3390/ijerph192013616. PMID: 36294194Free PMC Article
Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Liu D, Meng X, Tian Q, Cao W, Fan X, Wu L, Song M, Meng Q, Wang W, Wang Y
Adv Nutr 2022 Aug 1;13(4):1044-1062. doi: 10.1093/advances/nmab142. PMID: 34999745Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Kang E, Kim S, Rhee YE, Lee J, Yun YH
Psychol Health Med 2021 Sep;26(8):1031-1043. Epub 2020 Oct 23 doi: 10.1080/13548506.2020.1838585. PMID: 33095059

Recent systematic reviews

Remelli F, Ceresini MG, Trevisan C, Noale M, Volpato S
Aging Clin Exp Res 2022 Sep;34(9):1969-1983. Epub 2022 Jun 20 doi: 10.1007/s40520-022-02165-1. PMID: 35723858Free PMC Article
Larsson SC, Burgess S
BMC Med 2021 Dec 15;19(1):320. doi: 10.1186/s12916-021-02188-x. PMID: 34906131Free PMC Article
Kastner M, Cardoso R, Lai Y, Treister V, Hamid JS, Hayden L, Wong G, Ivers NM, Liu B, Marr S, Holroyd-Leduc J, Straus SE
CMAJ 2018 Aug 27;190(34):E1004-E1012. doi: 10.1503/cmaj.171391. PMID: 30150242Free PMC Article
Xu X, Mishra GD, Jones M
Ageing Res Rev 2017 Aug;37:53-68. Epub 2017 May 13 doi: 10.1016/j.arr.2017.05.003. PMID: 28511964
Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, Meinow B, Fratiglioni L
Ageing Res Rev 2011 Sep;10(4):430-9. Epub 2011 Mar 23 doi: 10.1016/j.arr.2011.03.003. PMID: 21402176

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