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AA amyloidosis

MedGen UID:
782429
Concept ID:
C3536715
Disease or Syndrome
Synonyms: Amyloid A amyloidosis; Secondary amyloidosis
SNOMED CT: Amyloid A amyloidosis (274945004); AA amyloidosis (274945004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:4000041
Monarch Initiative: MONDO:0019439
Orphanet: ORPHA85445

Definition

Extracellular tissue deposition of fibrils that are composed of fragments of and/or intact serum amyloid A protein, a hepatic acute phase reactant. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAA amyloidosis

Conditions with this feature

TNF receptor-associated periodic fever syndrome (TRAPS)
MedGen UID:
226899
Concept ID:
C1275126
Disease or Syndrome
Familial periodic fever (FPF) is an autoinflammatory disorder characterized by recurrent fever with localized myalgia and painful erythema. Febrile attacks may last 1 or 2 days but often last longer than 1 week. Arthralgia of large joints, abdominal pain, conjunctivitis, and periorbital edema are common features. During attacks, painless cutaneous lesions may develop on the trunk or extremities and may migrate distally (review by Drenth and van der Meer, 2001).

Professional guidelines

PubMed

Gurung R, Li T
Am J Med 2022 Apr;135 Suppl 1:S38-S43. Epub 2022 Jan 24 doi: 10.1016/j.amjmed.2022.01.003. PMID: 35085515
Ryšavá R
Nephrol Dial Transplant 2019 Sep 1;34(9):1460-1466. doi: 10.1093/ndt/gfy291. PMID: 30299492
Alkhawam H, Patel D, Nguyen J, Easaw SM, Al-Sadawi M, Syed U, Zaiem F, Homsi M, Vittorio TJ
Acta Cardiol 2017 Aug;72(4):380-389. Epub 2017 Jul 14 doi: 10.1080/00015385.2017.1335034. PMID: 28705053

Recent clinical studies

Etiology

Deshayes S, Aouba A, Grateau G, Georgin-Lavialle S
Int J Clin Pract 2021 Jun;75(6):e13966. Epub 2021 Jan 20 doi: 10.1111/ijcp.13966. PMID: 33368925
Spoladore R, Falasconi G, Marcatti M, Di Maio S, Fiore G, Slavich M, Margonato A, Turco A, Fragasso G
Expert Opin Pharmacother 2021 Mar;22(4):469-481. Epub 2020 Oct 31 doi: 10.1080/14656566.2020.1836159. PMID: 33043721
Ozdogan H, Ugurlu S
Presse Med 2019 Feb;48(1 Pt 2):e61-e76. Epub 2019 Jan 25 doi: 10.1016/j.lpm.2018.08.014. PMID: 30686512
Ryšavá R
Nephrol Dial Transplant 2019 Sep 1;34(9):1460-1466. doi: 10.1093/ndt/gfy291. PMID: 30299492
Bansal R, Syed U, Walfish J, Aron J, Walfish A
Curr Gastroenterol Rep 2018 Mar 26;20(3):11. doi: 10.1007/s11894-018-0616-y. PMID: 29582184

Diagnosis

Karam S, Haidous M, Royal V, Leung N
Kidney Int 2023 Mar;103(3):473-484. Epub 2022 Dec 9 doi: 10.1016/j.kint.2022.10.028. PMID: 36502873
Cudrici C, Deuitch N, Aksentijevich I
Int J Mol Sci 2020 May 5;21(9) doi: 10.3390/ijms21093263. PMID: 32380704Free PMC Article
Ryšavá R
Nephrol Dial Transplant 2019 Sep 1;34(9):1460-1466. doi: 10.1093/ndt/gfy291. PMID: 30299492
Papa R, Lachmann HJ
Rheum Dis Clin North Am 2018 Nov;44(4):585-603. Epub 2018 Sep 7 doi: 10.1016/j.rdc.2018.06.004. PMID: 30274625
Lachmann HJ
Best Pract Res Clin Rheumatol 2017 Aug;31(4):596-609. Epub 2018 Jan 11 doi: 10.1016/j.berh.2017.12.001. PMID: 29773275

Therapy

Hatemi G, Seyahi E, Fresko I, Talarico R, Uçar D, Hamuryudan V
Clin Exp Rheumatol 2023 Oct;41(10):1945-1954. Epub 2023 Oct 10 doi: 10.55563/clinexprheumatol/7kdo9x. PMID: 37877363
Gurung R, Li T
Am J Med 2022 Apr;135 Suppl 1:S38-S43. Epub 2022 Jan 24 doi: 10.1016/j.amjmed.2022.01.003. PMID: 35085515
Ozdogan H, Ugurlu S
Presse Med 2019 Feb;48(1 Pt 2):e61-e76. Epub 2019 Jan 25 doi: 10.1016/j.lpm.2018.08.014. PMID: 30686512
Lachmann HJ
Best Pract Res Clin Rheumatol 2017 Aug;31(4):596-609. Epub 2018 Jan 11 doi: 10.1016/j.berh.2017.12.001. PMID: 29773275
Pinney JH, Hawkins PN
Ann Clin Biochem 2012 May;49(Pt 3):229-41. Epub 2012 Mar 8 doi: 10.1258/acb.2011.011225. PMID: 22402917

Prognosis

Karam S, Haidous M, Royal V, Leung N
Kidney Int 2023 Mar;103(3):473-484. Epub 2022 Dec 9 doi: 10.1016/j.kint.2022.10.028. PMID: 36502873
Ryšavá R
Nephrol Dial Transplant 2019 Sep 1;34(9):1460-1466. doi: 10.1093/ndt/gfy291. PMID: 30299492
Bansal R, Syed U, Walfish J, Aron J, Walfish A
Curr Gastroenterol Rep 2018 Mar 26;20(3):11. doi: 10.1007/s11894-018-0616-y. PMID: 29582184
Pinney JH, Lachmann HJ
Subcell Biochem 2012;65:541-64. doi: 10.1007/978-94-007-5416-4_20. PMID: 23225016
Pinney JH, Hawkins PN
Ann Clin Biochem 2012 May;49(Pt 3):229-41. Epub 2012 Mar 8 doi: 10.1258/acb.2011.011225. PMID: 22402917

Clinical prediction guides

Ayed A, Salem MB, Letaief A, Salah MB, Handous I, Hamouda M, Aloui S, Skhiri H
Saudi J Kidney Dis Transpl 2022 May-Jun;33(3):432-439. doi: 10.4103/1319-2442.385967. PMID: 37843145
Khellaf G, Benziane A, Kaci L, Benabadji M
Clin Nephrol 2022 Mar;97(3):167-172. doi: 10.5414/CN110577. PMID: 34889732
Galkin AP
Prion 2021 Dec;15(1):53-55. doi: 10.1080/19336896.2021.1910468. PMID: 33876719Free PMC Article
Pinney JH, Lachmann HJ
Subcell Biochem 2012;65:541-64. doi: 10.1007/978-94-007-5416-4_20. PMID: 23225016
Obici L, Merlini G
Autoimmun Rev 2012 Nov;12(1):14-7. Epub 2012 Aug 2 doi: 10.1016/j.autrev.2012.07.016. PMID: 22878269

Recent systematic reviews

Karatemiz G, Esatoglu SN, Gurcan M, Ozguler Y, Yurdakul S, Hamuryudan V, Fresko I, Melikoglu M, Seyahi E, Ugurlu S, Ozdogan H, Yazici H, Hatemi G
Rheumatology (Oxford) 2022 Dec 23;62(1):9-18. doi: 10.1093/rheumatology/keac223. PMID: 35657376
Rodrigues F, Cuisset L, Cador-Rousseau B, Giurgea I, Neven B, Buob D, Quartier P, Hachulla E, Lequerré T, Cam G, Boursier G, Hervieu V, Grateau G, Georgin-Lavialle S
Rheumatology (Oxford) 2022 Nov 28;61(12):4827-4834. doi: 10.1093/rheumatology/keac145. PMID: 35262642
Delaleu J, Deshayes S, Rodrigues F, Savey L, Rivière E, Silva NM, Aouba A, Amselem S, Rabant M, Grateau G, Giurgea I, Georgin-Lavialle S
Rheumatology (Oxford) 2021 Dec 1;60(12):5775-5784. doi: 10.1093/rheumatology/keab252. PMID: 33715002
Brunger AF, Nienhuis HLA, Bijzet J, Hazenberg BPC
Amyloid 2020 Mar;27(1):1-12. Epub 2019 Nov 25 doi: 10.1080/13506129.2019.1693359. PMID: 31766892
Pettersson T, Konttinen YT, Maury CP
Expert Opin Pharmacother 2008 Aug;9(12):2117-28. doi: 10.1517/14656566.9.12.2117. PMID: 18671466

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