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Multifocal nodular oncocytic hyperplasia of salivary gland

MedGen UID:
784287
•Concept ID:
C3697021
•
Disease or Syndrome
Synonyms: Multifocal nodular hyperplasia of salivary gland; Nodular oncocytic hyperplasia; Nodular Oncocytic Hyperplasia
SNOMED CT: Nodular oncocytic hyperplasia (698071008); Multifocal nodular hyperplasia of salivary gland (698071008); Multifocal nodular oncocytic hyperplasia of salivary gland (698071008)

Definition

A rare lesion characterized by multiple non-neoplastic nodular proliferations composed of cells with abundant granular eosinophilic cytoplasm (oncocytes) and/or clear cytoplasm (clear cells) in one or both parotid glands. (WHO 2017) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultifocal nodular oncocytic hyperplasia of salivary gland

Recent clinical studies

Etiology

Oncocytic adenomas and oncocytic hyperplasia of salivary glands: a clinicopathological study of 26 cases.
Palmer TJ, Gleeson MJ, Eveson JW, Cawson RA
Histopathology 1990 May;16(5):487-93. doi: 10.1111/j.1365-2559.1990.tb01549.x. PMID: 2361662

Diagnosis

Bilateral multifocal nodular oncocytic hyperplasia of the parotid gland: a rare entity.
Hammami B, Thabet W, Kallel R, Boudawara T, Mnejja M, Charfeddine I
Pathologica 2021 Apr;113(2):131-135. doi: 10.32074/1591-951X-140. PMID: 34042095Free PMC Article
Familial bilateral nodular oncocytic hyperplasia of the parotid gland in mother and son.
Zhu Y, Cresswell M, Charnock JM, Reece P
BMJ Case Rep 2021 Apr 19;14(4) doi: 10.1136/bcr-2020-240980. PMID: 33875504Free PMC Article
Metachronous bilateral multifocal nodular oncocytic hyperplasia of the parotid gland.
Akbulut A, Kaptan ZK, Yasaran M, Karadas H, Koca G, Korkmaz M
J Stomatol Oral Maxillofac Surg 2019 Dec;120(6):598-600. Epub 2018 Dec 16 doi: 10.1016/j.jormas.2018.12.009. PMID: 30562624
Multifocal nodular oncocytic hyperplasia in parotid gland: a case report.
Goyal R, Ahuja A, Gupta N, Singh G, Vaiphei K
Acta Cytol 2007 Jul-Aug;51(4):621-3. doi: 10.1159/000325811. PMID: 17718138
Oncocytic adenomas and oncocytic hyperplasia of salivary glands: a clinicopathological study of 26 cases.
Palmer TJ, Gleeson MJ, Eveson JW, Cawson RA
Histopathology 1990 May;16(5):487-93. doi: 10.1111/j.1365-2559.1990.tb01549.x. PMID: 2361662

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