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Prostatic obstruction

MedGen UID:
78703
•Concept ID:
C0268889
•
Disease or Syndrome
Synonym: Prostatic Obstruction
SNOMED CT: Prostatic obstruction (4127004)

Definition

Squeezing of the urethra secondary to enlargement of the prostate gland, resulting in voiding symptoms (straining to void, slow urine stream, and incomplete emptying of the bladder). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstatic obstruction

Professional guidelines

PubMed

Surgical treatment options for benign prostatic obstruction: beyond prostate volume.
Deyirmendjian C, Elterman D, Chughtai B, Zorn KC, Bhojani N
Curr Opin Urol 2022 Jan 1;32(1):102-108. doi: 10.1097/MOU.0000000000000937. PMID: 34669611
Treatment of Concomitant OAB and BPH.
Moss MC, Rezan T, Karaman UR, Gomelsky A
Curr Urol Rep 2017 Jan;18(1):1. doi: 10.1007/s11934-017-0649-z. PMID: 28092069
The management of prostatic obstruction with urethral stents.
Peyton CC, Badlani GH
Can J Urol 2015 Oct;22 Suppl 1:75-81. PMID: 26497347

Recent clinical studies

Etiology

Benefits and Harms of Benign Prostatic Obstruction Treatments in Renal Transplanted Patients.
Zakri RH, Hevia V, Bossier R, Rodriguez-Faba O, Garcia EL, Budde K, Breda A, Olsburgh J, Figueiredo A
Eur Urol Focus 2023 Nov;9(6):913-919. Epub 2023 Aug 16 doi: 10.1016/j.euf.2023.05.001. PMID: 37596113
Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis.
Cornu JN, Zantek P, Burtt G, Martin C, Martin A, Springate C, Chughtai B
Eur Urol 2023 Jun;83(6):534-547. Epub 2023 Mar 22 doi: 10.1016/j.eururo.2023.02.028. PMID: 36964042
Prostatic artery embolization for benign prostatic obstruction: assessment of safety and efficacy.
Christidis D, Clarebrough E, Ly V, Perera M, Woo H, Lawrentschuk N, Bolton D
World J Urol 2018 Apr;36(4):575-584. Epub 2018 Feb 14 doi: 10.1007/s00345-018-2220-z. PMID: 29445846
Voiding dysfunction in older men.
Chung A, Noguchi N, Chan L, Tse V
Curr Opin Urol 2016 Mar;26(2):177-83. doi: 10.1097/MOU.0000000000000265. PMID: 26765045
Epidemiology of nocturia.
Hunskaar S
BJU Int 2005 Sep;96 Suppl 1:4-7. doi: 10.1111/j.1464-410X.2005.05650.x. PMID: 16086673

Diagnosis

Prostatic Artery Embolisation: Do We Still Need It and for Whom?
Abt D, Lyatoshinsky P, Schmid HP, Müllhaupt G
Eur Urol Focus 2022 Mar;8(2):384-387. Epub 2022 Apr 26 doi: 10.1016/j.euf.2022.04.005. PMID: 35484049
Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: 2-yr Outcomes of a Randomised, Open-label, Single-centre Trial.
Abt D, Müllhaupt G, Hechelhammer L, Markart S, Güsewell S, Schmid HP, Mordasini L, Engeler DS
Eur Urol 2021 Jul;80(1):34-42. Epub 2021 Feb 19 doi: 10.1016/j.eururo.2021.02.008. PMID: 33612376
Voiding dysfunction in older men.
Chung A, Noguchi N, Chan L, Tse V
Curr Opin Urol 2016 Mar;26(2):177-83. doi: 10.1097/MOU.0000000000000265. PMID: 26765045
Epidemiology of nocturia.
Hunskaar S
BJU Int 2005 Sep;96 Suppl 1:4-7. doi: 10.1111/j.1464-410X.2005.05650.x. PMID: 16086673
Voiding dysfunction: definitions.
Chaikin DC, Blaivas JG
Curr Opin Urol 2001 Jul;11(4):395-8. doi: 10.1097/00042307-200107000-00010. PMID: 11429500

Therapy

Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis.
Cornu JN, Zantek P, Burtt G, Martin C, Martin A, Springate C, Chughtai B
Eur Urol 2023 Jun;83(6):534-547. Epub 2023 Mar 22 doi: 10.1016/j.eururo.2023.02.028. PMID: 36964042
Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: 2-yr Outcomes of a Randomised, Open-label, Single-centre Trial.
Abt D, Müllhaupt G, Hechelhammer L, Markart S, Güsewell S, Schmid HP, Mordasini L, Engeler DS
Eur Urol 2021 Jul;80(1):34-42. Epub 2021 Feb 19 doi: 10.1016/j.eururo.2021.02.008. PMID: 33612376
Treatment of Concomitant OAB and BPH.
Moss MC, Rezan T, Karaman UR, Gomelsky A
Curr Urol Rep 2017 Jan;18(1):1. doi: 10.1007/s11934-017-0649-z. PMID: 28092069
Enucleation is enucleation is enucleation is enucleation.
Herrmann TR
World J Urol 2016 Oct;34(10):1353-5. Epub 2016 Sep 1 doi: 10.1007/s00345-016-1922-3. PMID: 27585786
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S
Eur Urol 2015 Jun;67(6):1066-1096. Epub 2014 Jun 25 doi: 10.1016/j.eururo.2014.06.017. PMID: 24972732

Prognosis

Incidental prostate cancer after holmium laser enucleation of the prostate-A narrative review.
Yilmaz M, Toprak T, Suarez-Ibarrola R, Sigle A, Gratzke C, Miernik A
Andrologia 2022 Apr;54(3):e14332. Epub 2021 Nov 26 doi: 10.1111/and.14332. PMID: 34837229
Prostatic inflammation: a potential treatment target for male LUTS due to benign prostatic obstruction.
Samarinas M, Gacci M, de la Taille A, Gravas S
Prostate Cancer Prostatic Dis 2018 Jun;21(2):161-167. Epub 2018 Apr 24 doi: 10.1038/s41391-018-0039-8. PMID: 29686417
Holmium Laser Enucleation of the Prostate in Patients Requiring Anticoagulation.
Rivera M, Krambeck A, Lingeman J
Curr Urol Rep 2017 Oct;18(10):77. doi: 10.1007/s11934-017-0727-2. PMID: 28780634
Incidence and Management of Lower Urinary Tract Symptoms After Urethral Stricture Repair.
Chung ASJ, McCammon KA
Curr Urol Rep 2017 Sep;18(9):70. doi: 10.1007/s11934-017-0716-5. PMID: 28718163
The management of prostatic obstruction with urethral stents.
Peyton CC, Badlani GH
Can J Urol 2015 Oct;22 Suppl 1:75-81. PMID: 26497347

Clinical prediction guides

Benefits and Harms of Benign Prostatic Obstruction Treatments in Renal Transplanted Patients.
Zakri RH, Hevia V, Bossier R, Rodriguez-Faba O, Garcia EL, Budde K, Breda A, Olsburgh J, Figueiredo A
Eur Urol Focus 2023 Nov;9(6):913-919. Epub 2023 Aug 16 doi: 10.1016/j.euf.2023.05.001. PMID: 37596113
Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis.
Cornu JN, Zantek P, Burtt G, Martin C, Martin A, Springate C, Chughtai B
Eur Urol 2023 Jun;83(6):534-547. Epub 2023 Mar 22 doi: 10.1016/j.eururo.2023.02.028. PMID: 36964042
Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: 2-yr Outcomes of a Randomised, Open-label, Single-centre Trial.
Abt D, Müllhaupt G, Hechelhammer L, Markart S, Güsewell S, Schmid HP, Mordasini L, Engeler DS
Eur Urol 2021 Jul;80(1):34-42. Epub 2021 Feb 19 doi: 10.1016/j.eururo.2021.02.008. PMID: 33612376
Prostatic artery embolization for benign prostatic obstruction: assessment of safety and efficacy.
Christidis D, Clarebrough E, Ly V, Perera M, Woo H, Lawrentschuk N, Bolton D
World J Urol 2018 Apr;36(4):575-584. Epub 2018 Feb 14 doi: 10.1007/s00345-018-2220-z. PMID: 29445846
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S
Eur Urol 2015 Jun;67(6):1066-1096. Epub 2014 Jun 25 doi: 10.1016/j.eururo.2014.06.017. PMID: 24972732

Recent systematic reviews

Comparing prostatic artery embolization to surgical and minimally invasive procedures for the treatment of benign prostatic hyperplasia: a systematic review and meta-analysis.
Altman R, Ferreira R, Barragan C, Bhojani N, Lajkosz K, Zorn KC, Chughtai B, Annamalai G, Elterman DS
BMC Urol 2024 Jan 28;24(1):22. doi: 10.1186/s12894-023-01397-1. PMID: 38281906Free PMC Article
Enucleation of the prostate as retreatment for recurrent or residual benign prostatic obstruction: a systematic review and a meta-analysis.
Pyrgidis N, Mykoniatis I, Lusuardi L, Schulz GB, Sokolakis I, Stief C, Sountoulides P
Prostate Cancer Prostatic Dis 2023 Dec;26(4):693-701. Epub 2023 May 16 doi: 10.1038/s41391-023-00677-z. PMID: 37193777
Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis.
Cornu JN, Zantek P, Burtt G, Martin C, Martin A, Springate C, Chughtai B
Eur Urol 2023 Jun;83(6):534-547. Epub 2023 Mar 22 doi: 10.1016/j.eururo.2023.02.028. PMID: 36964042
Early results and complications of prostatic arterial embolization for benign prostatic hyperplasia.
Lebdai S, Delongchamps NB, Sapoval M, Robert G, Amouyal G, Thiounn N, Karsenty G, Ruffion A, de La Taille A, Descazeaud A, Mathieu R
World J Urol 2016 May;34(5):625-32. Epub 2015 Aug 15 doi: 10.1007/s00345-015-1665-6. PMID: 26276151
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S
Eur Urol 2015 Jun;67(6):1066-1096. Epub 2014 Jun 25 doi: 10.1016/j.eururo.2014.06.017. PMID: 24972732

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