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Kandori fleck retina

MedGen UID:
78764
•Concept ID:
C0271257
•
Disease or Syndrome
Synonyms: Fleck retina of Kandori; Kandori's syndrome
SNOMED CT: Kandori fleck retina syndrome (765191009); Fleck retina of Kandori (765191009)
 
Monarch Initiative: MONDO:0009236
OMIM®: 228990
Orphanet: ORPHA99179

Definition

A rare genetic retinal dystrophy with characteristics of irregular, sharply defined, yellowish-white lesions of variable size that are distributed mainly in the nasal equatorial region of the retina, with a tendency to confluence, that are not associated with any vascular or optic nerve abnormalities. They frequently manifest as mild and stationary night blindness. [from SNOMEDCT_US]

Recent clinical studies

Etiology

Flecked retina disorders.
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338

Diagnosis

Late-onset night blindness with peripheral flecks accompanied by progressive trickle-like macular degeneration.
Tsunoda K, Fujinami K, Yoshitake K, Iwata T
Doc Ophthalmol 2019 Dec;139(3):171-184. Epub 2019 Jul 8 doi: 10.1007/s10633-019-09705-7. PMID: 31286363
Flecked retina disorders.
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338
Fleck retina.
Kandori F, Tamai A, Kurimoto S, Fukunaga K
Am J Ophthalmol 1972 May;73(5):673-85. doi: 10.1016/0002-9394(72)90385-6. PMID: 4537354
Electroretinographical studies on "fleck retina with congenital nonprogressive nightblindness".
Kandori F, Setogawa T, Tamai A
Yonago Acta Med 1966 Jul;10(2):98-108. PMID: 5298813

Clinical prediction guides

Flecked retina disorders.
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338

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