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Unresectable Extrahepatic Bile Duct Carcinoma

MedGen UID:
78887
•Concept ID:
C0278811
•
Neoplastic Process
Synonyms: Non-Resectable Extrahepatic Bile Duct Carcinoma; Unresectable Cancer of Extrahepatic Bile Duct; Unresectable Cancer of the Extrahepatic Bile Duct; Unresectable Extrahepatic Bile Duct Cancer

Definition

Extrahepatic bile duct carcinoma that is not amenable to surgical removal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Extrahepatic Bile Duct Carcinoma

Professional guidelines

PubMed

Clinical treatment of cholangiocarcinoma: an updated comprehensive review.
Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Cholangiocarcinoma: Diagnosis and Management.
Buckholz AP, Brown RS Jr
Clin Liver Dis 2020 Aug;24(3):421-436. Epub 2020 May 29 doi: 10.1016/j.cld.2020.04.005. PMID: 32620281

Recent clinical studies

Therapy

Intraluminal low-dose-rate 192Ir brachytherapy combined with external beam radiotherapy and biliary stenting for unresectable extrahepatic bile duct carcinoma.
Takamura A, Saito H, Kamada T, Hiramatsu K, Takeuchi S, Hasegawa M, Miyamoto N
Int J Radiat Oncol Biol Phys 2003 Dec 1;57(5):1357-65. doi: 10.1016/s0360-3016(03)00770-3. PMID: 14630274

Prognosis

Intraluminal low-dose-rate 192Ir brachytherapy combined with external beam radiotherapy and biliary stenting for unresectable extrahepatic bile duct carcinoma.
Takamura A, Saito H, Kamada T, Hiramatsu K, Takeuchi S, Hasegawa M, Miyamoto N
Int J Radiat Oncol Biol Phys 2003 Dec 1;57(5):1357-65. doi: 10.1016/s0360-3016(03)00770-3. PMID: 14630274

Clinical prediction guides

Intraluminal low-dose-rate 192Ir brachytherapy combined with external beam radiotherapy and biliary stenting for unresectable extrahepatic bile duct carcinoma.
Takamura A, Saito H, Kamada T, Hiramatsu K, Takeuchi S, Hasegawa M, Miyamoto N
Int J Radiat Oncol Biol Phys 2003 Dec 1;57(5):1357-65. doi: 10.1016/s0360-3016(03)00770-3. PMID: 14630274

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