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Classic Kaposi sarcoma

MedGen UID:
78931
Concept ID:
C0279084
Neoplastic Process
Synonyms: Classic Kaposi Sarcoma; classic Kaposi sarcoma; Classic Kaposi's Sarcoma; classic Kaposi's sarcoma; Kaposi Sarcoma Classical Type; Kaposi sarcoma classical type; Kaposi Sarcoma, Classic; Kaposi sarcoma, classic; Kaposi's Sarcoma, Classical Type; Kaposi's sarcoma, classical type
 
Monarch Initiative: MONDO:0022772

Definition

A vascular sarcoma that commonly occurs in the lower extremities. It occurs predominantly in elderly male patients of southern European ancestry. It is characterized by the presence of purple, red-blue, or dark brown macular lesions, plaques and nodules. This disease is usually slow growing, although it can spread to the lungs and the gastrointestinal tract. If necessary, cutaneous lesions can be treated with radiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVClassic Kaposi sarcoma

Professional guidelines

PubMed

Paksoy N, Khanmammadov N, Doğan İ, Ferhatoğlu F, Ahmed MA, Karaman S, Aydiner A
Medicine (Baltimore) 2023 Feb 3;102(5):e32866. doi: 10.1097/MD.0000000000032866. PMID: 36749246Free PMC Article
Requena C, Alsina M, Morgado-Carrasco D, Cruz J, Sanmartín O, Serra-Guillén C, Llombart B
Actas Dermosifiliogr (Engl Ed) 2018 Dec;109(10):878-887. Epub 2018 Sep 24 doi: 10.1016/j.ad.2018.06.013. PMID: 30262126
Pantanowitz L, Dezube BJ
Curr Opin Oncol 2004 Sep;16(5):443-9. doi: 10.1097/00001622-200409000-00006. PMID: 15314513

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Kaposi Sarcoma, 2022

Recent clinical studies

Etiology

Oyucu Orhan S, Bilgehan Sahin A, Cubukcu E, Deligonul A, Ocak B, Orhan B, Evrensel T
Bosn J Basic Med Sci 2021 Dec 1;21(6):746-751. doi: 10.17305/bjbms.2020.5329. PMID: 33596402Free PMC Article
Séverin D, Bessaoud F, Meftah N, Du Thanh A, Tretarre B, Guillot B, Makinson A
AIDS 2021 Mar 1;35(3):399-405. doi: 10.1097/QAD.0000000000002744. PMID: 33181532
Odyakmaz Demirsoy E, Bayramgürler D, Çağlayan Ç, Bilen N, Şikar Aktürk A, Kıran R
J Cutan Med Surg 2019 Sep/Oct;23(5):488-495. Epub 2019 May 9 doi: 10.1177/1203475419847954. PMID: 31072133
Kandaz M, Bahat Z, Guler OC, Canyilmaz E, Melikoglu M, Yoney A
Dermatol Ther 2018 Jul;31(4):e12605. Epub 2018 Apr 6 doi: 10.1111/dth.12605. PMID: 29633477
Iscovich J, Boffetta P, Franceschi S, Azizi E, Sarid R
Cancer 2000 Feb 1;88(3):500-17. PMID: 10649240

Diagnosis

Oyucu Orhan S, Bilgehan Sahin A, Cubukcu E, Deligonul A, Ocak B, Orhan B, Evrensel T
Bosn J Basic Med Sci 2021 Dec 1;21(6):746-751. doi: 10.17305/bjbms.2020.5329. PMID: 33596402Free PMC Article
Requena C, Alsina M, Morgado-Carrasco D, Cruz J, Sanmartín O, Serra-Guillén C, Llombart B
Actas Dermosifiliogr (Engl Ed) 2018 Dec;109(10):878-887. Epub 2018 Sep 24 doi: 10.1016/j.ad.2018.06.013. PMID: 30262126
Vincenzi B, D'Onofrio L, Frezza AM, Grasso RF, Fausti V, Santini D, Dei Tos AP, Tonini G
BMC Res Notes 2015 Apr 10;8:138. doi: 10.1186/s13104-015-1076-1. PMID: 25889316Free PMC Article
Solivetti FM, Elia F, Latini A, Cota C, Cordiali-Fei P, Di Carlo A
J Exp Clin Cancer Res 2011 Apr 13;30(1):40. doi: 10.1186/1756-9966-30-40. PMID: 21489270Free PMC Article
Pantanowitz L, Dezube BJ
Curr Opin Oncol 2004 Sep;16(5):443-9. doi: 10.1097/00001622-200409000-00006. PMID: 15314513

Therapy

Paksoy N, Khanmammadov N, Doğan İ, Ferhatoğlu F, Ahmed MA, Karaman S, Aydiner A
Medicine (Baltimore) 2023 Feb 3;102(5):e32866. doi: 10.1097/MD.0000000000032866. PMID: 36749246Free PMC Article
Oyucu Orhan S, Bilgehan Sahin A, Cubukcu E, Deligonul A, Ocak B, Orhan B, Evrensel T
Bosn J Basic Med Sci 2021 Dec 1;21(6):746-751. doi: 10.17305/bjbms.2020.5329. PMID: 33596402Free PMC Article
Requena C, Alsina M, Morgado-Carrasco D, Cruz J, Sanmartín O, Serra-Guillén C, Llombart B
Actas Dermosifiliogr (Engl Ed) 2018 Dec;109(10):878-887. Epub 2018 Sep 24 doi: 10.1016/j.ad.2018.06.013. PMID: 30262126
Régnier-Rosencher E, Guillot B, Dupin N
J Am Acad Dermatol 2013 Feb;68(2):313-31. Epub 2012 Jun 12 doi: 10.1016/j.jaad.2012.04.018. PMID: 22695100
Di Lorenzo G
Crit Rev Oncol Hematol 2008 Dec;68(3):242-9. Epub 2008 Jul 25 doi: 10.1016/j.critrevonc.2008.06.007. PMID: 18657433

Prognosis

Oyucu Orhan S, Bilgehan Sahin A, Cubukcu E, Deligonul A, Ocak B, Orhan B, Evrensel T
Bosn J Basic Med Sci 2021 Dec 1;21(6):746-751. doi: 10.17305/bjbms.2020.5329. PMID: 33596402Free PMC Article
Requena C, Alsina M, Morgado-Carrasco D, Cruz J, Sanmartín O, Serra-Guillén C, Llombart B
Actas Dermosifiliogr (Engl Ed) 2018 Dec;109(10):878-887. Epub 2018 Sep 24 doi: 10.1016/j.ad.2018.06.013. PMID: 30262126
Di Lorenzo G
Crit Rev Oncol Hematol 2008 Dec;68(3):242-9. Epub 2008 Jul 25 doi: 10.1016/j.critrevonc.2008.06.007. PMID: 18657433
Pantanowitz L, Dezube BJ
Curr Opin Oncol 2004 Sep;16(5):443-9. doi: 10.1097/00001622-200409000-00006. PMID: 15314513
Iscovich J, Boffetta P, Franceschi S, Azizi E, Sarid R
Cancer 2000 Feb 1;88(3):500-17. PMID: 10649240

Clinical prediction guides

Oyucu Orhan S, Bilgehan Sahin A, Cubukcu E, Deligonul A, Ocak B, Orhan B, Evrensel T
Bosn J Basic Med Sci 2021 Dec 1;21(6):746-751. doi: 10.17305/bjbms.2020.5329. PMID: 33596402Free PMC Article
Séverin D, Bessaoud F, Meftah N, Du Thanh A, Tretarre B, Guillot B, Makinson A
AIDS 2021 Mar 1;35(3):399-405. doi: 10.1097/QAD.0000000000002744. PMID: 33181532
Odyakmaz Demirsoy E, Bayramgürler D, Çağlayan Ç, Bilen N, Şikar Aktürk A, Kıran R
J Cutan Med Surg 2019 Sep/Oct;23(5):488-495. Epub 2019 May 9 doi: 10.1177/1203475419847954. PMID: 31072133
Goedert JJ, Martin MP, Vitale F, Lauria C, Whitby D, Qi Y, Gao X, Carrington M
J Infect Dis 2016 Feb 1;213(3):432-8. Epub 2015 Aug 12 doi: 10.1093/infdis/jiv413. PMID: 26268853Free PMC Article
Solivetti FM, Elia F, Latini A, Cota C, Cordiali-Fei P, Di Carlo A
J Exp Clin Cancer Res 2011 Apr 13;30(1):40. doi: 10.1186/1756-9966-30-40. PMID: 21489270Free PMC Article

Recent systematic reviews

Saerens M, Brusselaers N, Rottey S, Decruyenaere A, Creytens D, Lapeire L
Eur J Cancer 2021 Jul;152:165-182. Epub 2021 Jun 6 doi: 10.1016/j.ejca.2021.04.034. PMID: 34107450
Régnier-Rosencher E, Guillot B, Dupin N
J Am Acad Dermatol 2013 Feb;68(2):313-31. Epub 2012 Jun 12 doi: 10.1016/j.jaad.2012.04.018. PMID: 22695100

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2022
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Kaposi Sarcoma, 2022

    Consumer resources

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